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Select item 98534791.

Opioid Precursor Gene Expression in the Human Hypothalamus

RENAT R. SUKHOV, LARY C. WALKER, NAOMI E. RANCE, DONALD L. PRICE, W. SCOTT YOUNG, III

J Comp Neurol. Author manuscript; available in PMC 2023 Jan 20.

Published in final edited form as: J Comp Neurol. 1995 Mar 20; 353(4): 604–622. doi: 10.1002/cne.903530410

PMCID:: PMC9853479

Abstract Article PDF–3.1M

Select item 83590162.

PDYN, a gene implicated in brain/mental disorders, is targeted by REST in the adult human brain

Richard Henriksson, Cristina M. Bäckman, Brandon K. Harvey, Helena Kadyrova, Igor Bazov, Toni S. Shippenberg, Georgy Bakalkin

Biochim Biophys Acta. Author manuscript; available in PMC 2021 Aug 12.

Published in final edited form as: Biochim Biophys Acta. 2014 Nov; 1839(11): 1226–1232. Published online 2014 Sep 8. doi: 10.1016/j.bbagrm.2014.09.001

PMCID:: PMC8359016

Abstract Article PDF–481K

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 68877404.

Neuronal Expression of Opioid Gene is Controlled by Dual Epigenetic and Transcriptional Mechanism in Human Brain

Igor Bazov, Daniil Sarkisyan, Olga Kononenko, Hiroyuki Watanabe, Mumtaz Malik Taqi, Lada Stålhandske, Dineke S Verbeek, Jan Mulder, Grazyna Rajkowska, Donna Sheedy, Jillian Kril, Xueguang Sun, Ann-Christine Syvänen, Tatiana Yakovleva, Georgy Bakalkin

Cereb Cortex. 2018 Sep; 28(9): 3129–3142. Published online 2017 Jul 28. doi: 10.1093/cercor/bhx181

PMCID:: PMC6887740

Abstract Article PDF–1.1M

Select item 67377175.

Association between prodynorphin gene polymorphisms and opioid dependence susceptibility: a meta-analysis

Chang-wang Wang, Min Ma, Wei-guang Lu, Ru-qin Luo

BMC Psychiatry. 2019; 19: 281. Published online 2019 Sep 11. doi: 10.1186/s12888-019-2272-7

PMCID:: PMC6737717

Abstract Article PDF–517K

Select item 66222246.

Dynorphins Regulate Fear Memory: from Mice to Men

Andras Bilkei-Gorzo, Susanne Erk, Britta Schürmann, Daniela Mauer, Kerstin Michel, Henning Boecker, Lukas Scheef, Henrik Walter, Andreas Zimmer

J Neurosci. 2012 Jul 4; 32(27): 9335–9343. doi: 10.1523/JNEUROSCI.1034-12.2012

PMCID:: PMC6622224

Abstract Article PDF–944K

Select item 65948597.

Association of variants of prodynorphin promoter 68-bp repeats in Caucasians with opioid dependence diagnosis: Effect on age trajectory of heroin use

Vadim Yuferov, Matthew Randesi, Eduardo R Butelman, Wim van den Brink, Peter Blanken, Jan M van Ree, Jürg Ott, Mary Jeanne Kreek

Neurosci Lett. Author manuscript; available in PMC 2020 Jun 21.

Published in final edited form as: Neurosci Lett. 2019 Jun 21; 704: 100–105. Published online 2019 Mar 29. doi: 10.1016/j.neulet.2019.03.038

PMCID:: PMC6594859

Abstract Article PDF–422K

Select item 61487558.

Potentially Functional Polymorphism in the Promoter Region of Prodynorphin Gene May Be Associated With Protection Against Cocaine Dependence or Abuse

Andrew C.H. Chen, K. Steven LaForge, Ann Ho, Pauline F. McHugh, Scott Kellogg, Kathy Bell, Rosemary P. Schluger, Suzanne M. Leal, Mary Jeanne Kreek

Am J Med Genet. Author manuscript; available in PMC 2018 Sep 21.

Published in final edited form as: Am J Med Genet. 2002 May 8; 114(4): 429–435. doi: 10.1002/ajmg.10362

PMCID:: PMC6148755

Abstract Article PDF–473K

Select item 60611619.

Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics

Igor Bazov, Daniil Sarkisyan, Olga Kononenko, Hiroyuki Watanabe, Tatiana Yakovleva, Anita C. Hansson, Wolfgang H. Sommer, Rainer Spanagel, Georgy Bakalkin

Mol Neurobiol. 2018; 55(8): 7049–7061. Published online 2018 Jan 30. doi: 10.1007/s12035-017-0844-4

PMCID:: PMC6061161

Abstract Article PDF–2.5M

Select item 601043410.

Downregulation of the neuronal opioid gene expression concomitantly with neuronal decline in dorsolateral prefrontal cortex of human alcoholics

Igor Bazov, Daniil Sarkisyan, Olga Kononenko, Hiroyuki Watanabe, Victor M. Karpyak, Tatiana Yakovleva, Georgy Bakalkin

Transl Psychiatry. 2018; 8: 122. Published online 2018 Jun 20. doi: 10.1038/s41398-017-0075-5

PMCID:: PMC6010434

Abstract Article PDF–1.3M

Select item 585956611.

Regulation of gene transcription in bipolar disorders: Role of DNA methylation in the relationship between prodynorphin and brain derived neurotrophic factor

Claudio D’Addario, Maria Carlotta Palazzo, Beatrice Benatti, Benedetta Grancini, Mariangela Pucci, Andrea Di Francesco, Giulia Camuri, Daniela Galimberti, Chiara Fenoglio, Elio Scarpini, A. Carlo Altamura, Mauro Maccarrone, Bernardo Dell’Osso

Prog Neuropsychopharmacol Biol Psychiatry. Author manuscript; available in PMC 2018 Apr 2.

Published in final edited form as: Prog Neuropsychopharmacol Biol Psychiatry. 2018 Mar 2; 82: 314–321. Published online 2017 Aug 19. doi: 10.1016/j.pnpbp.2017.08.011

PMCID:: PMC5859566

Abstract Article PDF–597K

Select item 553161112.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 491015013.

F-box only protein 9 is an E3 ubiquitin ligase of PPARγ

Kyeong Won Lee, Soo Heon Kwak, Young Do Koo, Yun-Kyung Cho, Hak Mo Lee, Hye Seung Jung, Young Min Cho, Young Joo Park, Sung Soo Chung, Kyong Soo Park

Exp Mol Med. 2016 May; 48(5): e234. Published online 2016 May 20. doi: 10.1038/emm.2016.31

PMCID:: PMC4910150

Abstract Article PDF–1.1M

Select item 482444414.

Dynorphin 1-17 and Its N-Terminal Biotransformation Fragments Modulate Lipopolysaccharide-Stimulated Nuclear Factor-kappa B Nuclear Translocation, Interleukin-1beta and Tumor Necrosis Factor-alpha in Differentiated THP-1 Cells

Siti Sarah Fazalul Rahiman, Michael Morgan, Paul Gray, Paul Nicholas Shaw, Peter John Cabot

PLoS One. 2016; 11(4): e0153005. Published online 2016 Apr 7. doi: 10.1371/journal.pone.0153005

PMCID:: PMC4824444

Abstract Article PDF–4.2M

Select item 462153015.

Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent

Stacey J. Winham, Ulrich W. Preuss, Jennifer R. Geske, Peter Zill, John A. Heit, Georgy Bakalkin, Joanna M. Biernacka, Victor M. Karpyak

Sci Rep. 2015; 5: 15670. Published online 2015 Oct 27. doi: 10.1038/srep15670

PMCID:: PMC4621530

Abstract Article PDF–382K

Select item 461721116.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 409604817.

Genome-wide SNP Associations with Rubella-Specific Cytokine Responses in Measles-Mumps-Rubella Vaccine Recipients

Richard B. Kennedy, Inna G. Ovsyannikova, Iana H. Haralambieva, Nathaniel D. Lambert, V. Shane Pankratz, Gregory A. Poland

Immunogenetics. Author manuscript; available in PMC 2015 Aug 1.

Published in final edited form as: Immunogenetics. 2014 Aug; 66(0): 493–499. Published online 2014 May 9. doi: 10.1007/s00251-014-0776-3

PMCID:: PMC4096048

Abstract Article PDF–279K

Select item 393497818.

A Genetic Polymorphism of the Endogenous Opioid Dynorphin Modulates Monetary Reward Anticipation in the Corticostriatal Loop

Mikhail Votinov, Juergen Pripfl, Christian Windischberger, Klaudius Kalcher, Alexander Zimprich, Fritz Zimprich, Ewald Moser, Claus Lamm, Uta Sailer

PLoS One. 2014; 9(2): e89954. Published online 2014 Feb 25. doi: 10.1371/journal.pone.0089954

PMCID:: PMC3934978

Abstract Article PDF–1.1M

Select item 390131819.

Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states

Victor M. Karpyak, Stacey J. Winham, Ulrich W. Preuss, Peter Zill, Julie M. Cunningham, Denise L. Walker, Kriste A. Lewis, Jennifer R. Geske, Colin L. Colby, Osama A. Abulseoud, Daniel K. Hall-Flavin, Larissa L. Loukianova, Terry D. Schneekloth, Mark A Frye, Igor Bazov, John A. Heit, Georgy Bakalkin, David A. Mrazek, Joanna M. Biernacka

Int J Neuropsychopharmacol. Author manuscript; available in PMC 2014 Jan 24.

Published in final edited form as: Int J Neuropsychopharmacol. 2013 Jun; 16(5): 975–985. Published online 2012 Oct 29. doi: 10.1017/S1461145712001137

PMCID:: PMC3901318

Abstract Article PDF–568K

Select item 389667620.

Neurocognitive and neuroinflammatory correlates of PDYN and OPRK1 mRNA expression in the anterior cingulate in postmortem brain of HIV-infected subjects

Vadim Yuferov, Eduardo R Butelman, Ann Ho, Susan Morgello, Mary Jeanne Kreek

J Neuroinflammation. 2014; 11: 5. Published online 2014 Jan 9. doi: 10.1186/1742-2094-11-5

PMCID:: PMC3896676

Abstract Article PDF–381K

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