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Select item 111137061.

Protease-activated-receptor-2 affects protease-activated-receptor-1-driven breast cancer

Mohammad Jaber, Miriam Maoz, Arun Kancharla, Daniel Agranovich, Tamar Peretz, Sorina Grisaru-Granovsky, Beatrice Uziely, Rachel Bar-Shavit

Cell Mol Life Sci. 2014 Jul; 71(13): 2517–2533. Published online 2013 Nov 1. doi: 10.1007/s00018-013-1498-7

Correction in:: Cell Mol Life Sci. 2017 Feb; 74(3): 571–577.

PMCID:: PMC11113706

Abstract Article PDF–1.6M

Select item 107864042.

A novel trypsin of Trichinella spiralis mediates larval invasion of gut epithelium via binding to PAR2 and activating ERK1/2 pathway

Lu Lu Han, Qi Qi Lu, Wen Wen Zheng, Yang Li Li, Yan Yan Song, Xin Zhuo Zhang, Shao Rong Long, Ruo Dan Liu, Zhong Quan Wang, Jing Cui

PLoS Negl Trop Dis. 2024 Jan; 18(1): e0011874. Published online 2024 Jan 2. doi: 10.1371/journal.pntd.0011874

PMCID:: PMC10786404

Abstract Article PDF–6.5M

Select item 107441993.

Single-Nucleotide Polymorphisms of the PAR2 and IL-17A Genes Are Significantly Associated with Chronic Pain

Moe Soeda, Seii Ohka, Daisuke Nishizawa, Masako Iseki, Keisuke Yamaguchi, Hideko Arita, Kazuo Hanaoka, Jitsu Kato, Setsuro Ogawa, Ayako Hiranuma, Junko Hasegawa, Kyoko Nakayama, Yuko Ebata, Masakazu Hayashida, Tatsuya Ichinohe, Ken-ichi Fukuda, Kazutaka Ikeda

Int J Mol Sci. 2023 Dec; 24(24): 17627. Published online 2023 Dec 18. doi: 10.3390/ijms242417627

PMCID:: PMC10744199

Abstract Article PDF–1.0M

Select item 104778934.

Shear Stress Drives the Cleavage Activation of Protease‐Activated Receptor 2 by PRSS3/Mesotrypsin to Promote Invasion and Metastasis of Circulating Lung Cancer Cells

Muya Zhou, Koukou Li, Kathy Qian Luo

Adv Sci (Weinh) 2023 Sep; 10(25): 2301059. Published online 2023 Jul 3. doi: 10.1002/advs.202301059

PMCID:: PMC10477893

Abstract Article PDF–6.3M

Select item 101054625.

Protease secretions by the invading blastocyst induce calcium oscillations in endometrial epithelial cells via the protease-activated receptor 2

Aurélie Hennes, Johanna Devroe, Katrien De Clercq, Martina Ciprietti, Katharina Held, Katrien Luyten, Nele Van Ranst, Nina Maenhoudt, Karen Peeraer, Hugo Vankelecom, Thomas Voets, Joris Vriens

Reprod Biol Endocrinol. 2023; 21: 37. Published online 2023 Apr 15. doi: 10.1186/s12958-023-01085-7

PMCID:: PMC10105462

Abstract Article PDF–7.7M

Select item 98418026.

PAR2: The Cornerstone of Pancreatic Diseases

Petr SUHAJ, Tomas OLEJAR, Radoslav MATEJ

Physiol Res. 2022 Oct; 71(5): 583–596. Published online 2022 Sep 8. doi: 10.33549/physiolres.934931

PMCID:: PMC9841802

Abstract Article PDF–1.6M

Select item 96136367.

GPR97 triggers inflammatory processes in human neutrophils via a macromolecular complex upstream of PAR2 activation

Tai-Ying Chu, Céline Zheng-Gérard, Kuan-Yeh Huang, Yu-Chi Chang, Ying-Wen Chen, Kuan-Yu I, Yu-Ling Lo, Nien-Yi Chiang, Hsin-Yi Chen, Martin Stacey, Siamon Gordon, Wen-Yi Tseng, Chiao-Yin Sun, Yen-Mu Wu, Yi-Shin Pan, Chien-Hao Huang, Chun-Yen Lin, Tse-Ching Chen, Kamel El Omari, Marilina Antonelou, Scott R. Henderson, Alan Salama, Elena Seiradake, Hsi-Hsien Lin

Nat Commun. 2022; 13: 6385. Published online 2022 Oct 27. doi: 10.1038/s41467-022-34083-1

PMCID:: PMC9613636

Abstract Article PDF–4.0M

Select item 95844198.

Trypsin may be associated with duodenal eosinophils through the expression of PAR2 in early chronic pancreatitis and functional dyspepsia with pancreatic enzyme abnormalities

Shuhei Agawa, Seiji Futagami, Hiroshi Yamawaki, Rina Tsushima, Kazutoshi Higuchi, Mayu Habiro, Rie Kawawa, Yasuhiro Kodaka, Nobue Ueki, Yoshiyuki Watanabe, Katya Gudis, Rhuji Ohashi, Katsuhiko Iwakiri

PLoS One. 2022; 17(10): e0275341. Published online 2022 Oct 20. doi: 10.1371/journal.pone.0275341

PMCID:: PMC9584419

Abstract Article PDF–3.9M

Select item 92770609.

Candida albicans Sap6 Initiates Oral Mucosal Inflammation via the Protease Activated Receptor PAR2

Rohitashw Kumar, Isolde Gina Rojas, Mira Edgerton

Front Immunol. 2022; 13: 912748. Published online 2022 Jun 29. doi: 10.3389/fimmu.2022.912748

PMCID:: PMC9277060

Abstract Article PDF–7.7M

Select item 890959210.

Modulation of Intestinal Epithelial Permeability via Protease-Activated Receptor-2-Induced Autophagy

Yuju Kim, Yunna Lee, Gwangbeom Heo, Sihyun Jeong, Soyeong Park, Jin-Wook Yoo, Yunjin Jung, Eunok Im

Cells. 2022 Mar; 11(5): 878. Published online 2022 Mar 3. doi: 10.3390/cells11050878

PMCID:: PMC8909592

Abstract Article PDF–12M

Select item 882244811.

Cold pain sensitivity is associated with single-nucleotide polymorphisms of PAR2/F2RL1 and TRPM8

Moe Soeda, Seii Ohka, Daisuke Nishizawa, Junko Hasegawa, Kyoko Nakayama, Yuko Ebata, Tatsuya Ichinohe, Ken-ichi Fukuda, Kazutaka Ikeda

Mol Pain. 2021; 17: 17448069211002009. Published online 2021 Mar 25. doi: 10.1177/17448069211002009

PMCID:: PMC8822448

Abstract Article PDF–479K

Select item 879233412.

Alternaria alternata-induced airway epithelial signaling and inflammatory responses via protease-activated receptor-2 expression

Candy M. Rivas, Hillary Schiff, Aubin Moutal, Rajesh Khanna, Pawel R. Kiela, Gregory Dussor, Theodore J Price, Josef Vagner, Kathryn A. DeFea, Scott Boitano

Biochem Biophys Res Commun. Author manuscript; available in PMC 2023 Feb 5.

Published in final edited form as: Biochem Biophys Res Commun. 2022 Feb 5; 591: 13–19. Published online 2021 Dec 29. doi: 10.1016/j.bbrc.2021.12.090

PMCID:: PMC8792334

Abstract Article PDF–1.2M

Select item 868842113.

The activation fragment of PAR2 is elevated in serum from patients with rheumatoid arthritis and reduced in response to anti-IL6R treatment

Stefania Kalogera, Yi He, Anne-Christine Bay-Jensen, Thorbjørn Gantzel, Shu Sun, Tina Manon-Jensen, Morten Asser Karsdal, Christian S. Thudium

Sci Rep. 2021; 11: 24285. Published online 2021 Dec 20. doi: 10.1038/s41598-021-03346-0

PMCID:: PMC8688421

Abstract Article PDF–1.3M

Select item 865320714.

Disruption of the biological activity of protease‐activated receptors2/4 in adults rather than children in SARS CoV‐2 virus‐mediated mortality in COVID‐19 infection

Yogendra Singh, Neeraj Kumar Fuloria, Shivkanya Fuloria, Vetriselvan Subramaniyan, Waleed Hassan Almalki, Gaurav Gupta, Mohammad Arshad Javed Shaikh, Mahaveer Singh, Fahad A. Al‐Abbasi, Imran Kazmi

Drug Dev Res. 2021 Dec; 82(8): 1075–1078. Published online 2021 Sep 1. doi: 10.1002/ddr.21874

PMCID:: PMC8653207

Abstract Article PDF–823K

Select item 831259815.

Mast cell tryptase enhances wound healing by promoting migration in human bronchial epithelial cells

Sofia Mogren, Frida Berlin, Sangeetha Ramu, Asger Sverrild, Celeste Porsbjerg, Lena Uller, Cecilia K Andersson

Cell Adh Migr. 2021; 15(1): 202–214. Published online 2021 Jul 24. doi: 10.1080/19336918.2021.1950594

PMCID:: PMC8312598

Abstract Article PDF–1.5M

Select item 823607816.

Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs

Katherine M. Almasy, Jonathan P. Davies, Lars Plate

Mol Cell Proteomics. 2021; 20: 100120. Published online 2021 Jun 27. doi: 10.1016/j.mcpro.2021.100120

PMCID:: PMC8236078

Abstract Article PDF–4.6M

Select item 822972717.

The Role of Protease-Activated Receptor 2 in Hepatocellular Carcinoma after Hepatectomy

Ming-Chao Tsai, Chih-Che Lin, Ding-Wei Chen, Yueh-Wei Liu, Yi-Ju Wu, Yi-Hao Yen, Pao-Yuan Huang, Chih-Chien Yao, Ching-Hui Chuang, Chang-Chun Hsiao

Medicina (Kaunas) 2021 Jun; 57(6): 574. Published online 2021 Jun 4. doi: 10.3390/medicina57060574

PMCID:: PMC8229727

Abstract Article PDF–1.5M

Select item 816503018.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 808164219.

PAR2 Promoter Hypomethylation Regulates PAR2 Gene Expression and Promotes Lung Adenocarcinoma Cell Progression

Kuan Wu, Lei Xu, Ling Cheng

Comput Math Methods Med. 2021; 2021: 5542485. Published online 2021 Apr 15. doi: 10.1155/2021/5542485

PMCID:: PMC8081642

Abstract Article PDF–1.7M

Select item 799377120.

Expression of protease activated receptor-2 is reduced in renal cell carcinoma biopsies and cell lines

Christudas Morais, Retnagowri Rajandram, Jade S. Blakeney, Abishek Iyer, Jacky Y. Suen, David W. Johnson, Glenda C. Gobe, David P. Fairlie, David A. Vesey

PLoS One. 2021; 16(3): e0248983. Published online 2021 Mar 25. doi: 10.1371/journal.pone.0248983

PMCID:: PMC7993771

Abstract Article PDF–1.0M

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