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Select item 111602861.

Synergistic decline in expressions of p73 and p21 with invasion in esophageal cancers

Norihiro Masuda, Hiroyuki Kato, Takashi Nakajima, Takaaki Sano, Kenji Kashiwabara, Tetsunari Oyama, Hiroyuki Kuwano

Cancer Sci. 2003 Jul; 94(7): 612–617. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01491.x

PMCID:: PMC11160286

Abstract Article PDF–589K

Select item 111598462.

DIXDC1 targets p21 and cyclin D1 via PI3K pathway activation to promote colon cancer cell proliferation

Lei Wang, Xi‐Xi Cao, Qi Chen, Teng‐Fang Zhu, Hong‐Guang Zhu, Li Zheng

Cancer Sci. 2009 Oct; 100(10): 1801–1808. Published online 2009 Jun 17. doi: 10.1111/j.1349-7006.2009.01246.x

PMCID:: PMC11159846

Abstract Article PDF–6.3M

Select item 111318553.

Progesterone inhibits human endothelial cell proliferation through a p53-dependent pathway

S.-P. Hsu, P.-Y. Ho, S.-H. Juan, Y.-C. Liang, W.-S. Lee

Cell Mol Life Sci. 2008 Dec; 65(23): 3839–3850. Published online 2008 Oct 14. doi: 10.1007/s00018-008-8441-3

PMCID:: PMC11131855

Abstract Article PDF–1.2M

Select item 111148924.

Role of p21 in SP600125-induced cell cycle arrest, endoreduplication, and apoptosis

Dong-Oh Moon, Yung Hyun Choi, Gi-Young Kim

Cell Mol Life Sci. 2011 Oct; 68(19): 3249–3260. Published online 2011 Feb 11. doi: 10.1007/s00018-011-0626-5

PMCID:: PMC11114892

Abstract Article PDF–769K

Select item 109791135.

Transcriptome analysis of polyploid giant cancer cells and their progeny reveals a functional role for p21 in polyploidization and depolyploidization

Shai White-Gilbertson, Ping Lu, Ozge Saatci, Ozgur Sahin, Joe R. Delaney, Besim Ogretmen, Christina Voelkel-Johnson

J Biol Chem. 2024 Apr; 300(4): 107136. Published online 2024 Mar 4. doi: 10.1016/j.jbc.2024.107136

PMCID:: PMC10979113

Abstract Article PDF–3.4M

Select item 108994066.

ATM-Mediated translocation of RanBPM regulates DNA damage response by stabilizing p21 in non-small cell lung cancer cells

Tanggang Deng, Lin Xie, Chen Xiaofang, Zhenbin Zhang, Yugang Xiao, Yuchong Peng, Linglong Yin, Yongming Fu, Xiong Li

Cell Oncol (Dordr) 2024; 47(1): 245–258. Published online 2023 Sep 7. doi: 10.1007/s13402-023-00866-x

PMCID:: PMC10899406

Abstract Article PDF–8.3M

Select item 107700817.

CLIC3 interacts with NAT10 to inhibit N4-acetylcytidine modification of p21 mRNA and promote bladder cancer progression

Yujun Shuai, Hui Zhang, Changhao Liu, Junting Wang, Yangkai Jiang, Jiayin Sun, Xincheng Gao, Xiaochen Bo, Xingyuan Xiao, Xin Liao, Chao Huang, Hebing Chen, Guosong Jiang

Cell Death Dis. 2024 Jan; 15(1): 9. Published online 2024 Jan 5. doi: 10.1038/s41419-023-06373-z

PMCID:: PMC10770081

Abstract Article PDF–6.9M

Select item 107438488.

CDKN1A/p21 in Breast Cancer: Part of the Problem, or Part of the Solution?

Evangelos Manousakis, Clàudia Martinez Miralles, Maria Guimerà Esquerda, Roni H. G. Wright

Int J Mol Sci. 2023 Dec; 24(24): 17488. Published online 2023 Dec 14. doi: 10.3390/ijms242417488

PMCID:: PMC10743848

Abstract Article PDF–2.2M

Select item 106851729.

Elevated CDKN1A (P21) mediates β-thalassemia erythroid apoptosis, but its loss does not improve β-thalassemic erythropoiesis

Raymond Liang, Miao Lin, Vijay Menon, Jiajing Qiu, Anagha Menon, Laura Breda, Tasleem Arif, Stefano Rivella, Saghi Ghaffari

Blood Adv. 2023 Nov 28; 7(22): 6873–6885. Published online 2023 Sep 9. doi: 10.1182/bloodadvances.2022007655

PMCID:: PMC10685172

Abstract Article PDF–1.5M

Select item 1068173010.

Long non-coding RNA generated from CDKN1A gene by alternative polyadenylation regulates p21 expression during DNA damage response

Michael R Murphy, Anthony Ramadei, Ahmet Doymaz, Sophia Varriano, Devorah M Natelson, Amy Yu, Sera Aktas, Marie Mazzeo, Michael Mazzeo, George Zakusilo, Frida E Kleiman

Nucleic Acids Res. 2023 Nov 27; 51(21): 11911–11926. Published online 2023 Oct 23. doi: 10.1093/nar/gkad899

PMCID:: PMC10681730

Abstract Article PDF–1.8M

Select item 1051027411.

Polymorphism at codon 31 of CDKN1A (p21) as a predictive factor for bevacizumab therapy in glioblastoma multiforme

Wen-Yu Cheng, Chiung-Chyi Shen, Yea-Jiuen Liang, Ming-Tsang Chiao, Yi-Chin Yang, Wan-Yu Hsieh, Cheng-Hui Lin, Jun-Peng Chen

BMC Cancer. 2023; 23: 886. Published online 2023 Sep 20. doi: 10.1186/s12885-023-11400-5

PMCID:: PMC10510274

Abstract Article PDF–2.3M

Select item 1049589512.

TP53 (rs1042522, rs28934571) and TP21 (rs1801270, rs1059234) Polymorphisms and Risk of Breast Cancer among Rural Women of Maharashtra: Findings from a Hospital Based Case- Control Study

Kailas D Datkhile, Suresh J Bhosale, Pratik P Durgawale, Nilam J Jagdale, Ashwini L More, Rashmi A Gudur, Anand K Gudur, Satish R Patil

Asian Pac J Cancer Prev. 2023; 24(5): 1611–1619. doi: 10.31557/APJCP.2023.24.5.1611

PMCID:: PMC10495895

Abstract Article PDF–401K

Select item 1033919613.

A genome-wide screen reveals that Dyrk1A kinase promotes nucleotide excision repair by preventing aberrant overexpression of cyclin D1 and p21

François Bélanger, Cassandra Roussel, Christina Sawchyn, Edlie St-Hilaire, Sari Gezzar-Dandashi, Aimé Boris Kimenyi Ishimwe, Frédérick Antoine Mallette, Hugo Wurtele, Elliot Drobetsky

J Biol Chem. 2023 Jul; 299(7): 104900. Published online 2023 Jun 9. doi: 10.1016/j.jbc.2023.104900

PMCID:: PMC10339196

Abstract Article PDF–2.2M

Select item 1018192914.

N6-methyladenosine reader YTHDF2 promotes multiple myeloma cell proliferation through EGR1/p21^cip1/waf1/CDK2-Cyclin E1 axis-mediated cell cycle transition

Rui Liu, Jiyu Miao, Yachun Jia, Guangyao Kong, Fei Hong, Fangmei Li, Meng Zhai, Ru Zhang, Jiaxi Liu, Xuezhu Xu, Ting Wang, Hui Liu, Jinsong Hu, Yun Yang, Aili He

Oncogene. 2023; 42(20): 1607–1619. Published online 2023 Apr 3. doi: 10.1038/s41388-023-02675-w

PMCID:: PMC10181929

Abstract Article PDF–6.7M

Select item 1011960215.

Latent CSN-CRL complexes are crucial for curcumin-induced apoptosis and recruited during adipogenesis to lipid droplets via small GTPase RAB18

Dawadschargal Dubiel, Jing Wang, Roland Hartig, Supattra Chaithongyot, Wolfgang Dubiel, Michael Naumann

iScience. 2023 Apr 21; 26(4): 106468. Published online 2023 Mar 22. doi: 10.1016/j.isci.2023.106468

PMCID:: PMC10119602

Abstract Article PDF–6.6M

Select item 993386216.

Proximity Labeling Reveals Spatial Regulation of the Anaphase-Promoting Complex/Cyclosome by a Microtubule Adaptor

Xiaofu Cao, Adnan Shami Shah, Ethan J. Sanford, Marcus B. Smolka, Jeremy M. Baskin

ACS Chem Biol. Author manuscript; available in PMC 2023 Sep 16.

Published in final edited form as: ACS Chem Biol. 2022 Sep 16; 17(9): 2605–2618. Published online 2022 Aug 11. doi: 10.1021/acschembio.2c00527

PMCID:: PMC9933862

Abstract Article PDF–2.5M

Select item 975522917.

Inhibition of p21 activates Akt kinase to trigger ROS-induced autophagy and impacts on tumor growth rate

Mayank Maheshwari, Nisha Yadav, Mohammad Hasanain, Praveen Pandey, Rohit Sahai, Kuldeep Choyal, Akhilesh Singh, Mushtaq A. Nengroo, Krishan K. Saini, Deepak Kumar, Kalyan Mitra, Dipak Datta, Jayanta Sarkar

Cell Death Dis. 2022 Dec; 13(12): 1045. Published online 2022 Dec 15. doi: 10.1038/s41419-022-05486-1

PMCID:: PMC9755229

Abstract Article PDF–5.1M

Select item 974755018.

Gene polymorphisms of cyclin‐dependent kinase inhibitor and matrix metalloproteinase‐9 in Sudanese patients with esophageal squamous cell carcinoma

Majdolin Mohammed Eltayeb, Mohamed M. Ali, Saeed M. Omar, Nouh Saad Mohamed, Ishag Adam, Hamdan Z. Hamdan

Mol Genet Genomic Med. 2022 Dec; 10(12): e2074. Published online 2022 Oct 19. doi: 10.1002/mgg3.2074

PMCID:: PMC9747550

Abstract Article PDF–415K

Select item 973769619.

Genome-Wide Association Study Identifies CDKN1A as a Novel Locus Associated with Muscle Fiber Composition

Ekaterina A. Semenova, Hirofumi Zempo, Eri Miyamoto-Mikami, Hiroshi Kumagai, Andrey K. Larin, Rinat I. Sultanov, Konstantin A. Babalyan, Andrey V. Zhelankin, Takuro Tobina, Keisuke Shiose, Ryo Kakigi, Takamasa Tsuzuki, Noriko Ichinoseki-Sekine, Hiroyuki Kobayashi, Hisashi Naito, Jatin Burniston, Edward V. Generozov, Noriyuki Fuku, Ildus I. Ahmetov

Cells. 2022 Dec; 11(23): 3910. Published online 2022 Dec 2. doi: 10.3390/cells11233910