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Select item 111520581.

Antagonism Between PEDF and TGF-β Contributes to Type VI Osteogenesis Imperfecta Bone and Vascular Pathogenesis

Heeseog Kang, Smriti Aryal AC, Aileen M Barnes, Aline Martin, Valentin David, Susan E Crawford, Joan C Marini

J Bone Miner Res. Author manuscript; available in PMC 2024 Jun 5.

Published in final edited form as: J Bone Miner Res. 2022 May; 37(5): 925–937. Published online 2022 Apr 13. doi: 10.1002/jbmr.4540

PMCID:: PMC11152058

Abstract Article PDF–1.8M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108282833.

PEDF protects retinal pigment epithelium from ferroptosis and ameliorates dry AMD-like pathology in a murine model

Wei Xiang, Longhui Li, Qin Zhao, Yongcheng Zeng, Jinhui Shi, Zitong Chen, Guoquan Gao, Kunbei Lai

GeroScience. 2024 Apr; 46(2): 2697–2714. Published online 2023 Dec 28. doi: 10.1007/s11357-023-01038-3

PMCID:: PMC10828283

Abstract Article PDF–13M

Select item 93160024.

PEDF Deletion Induces Senescence and Defects in Phagocytosis in the RPE

Ivan T. Rebustini, Susan E. Crawford, S. Patricia Becerra

Int J Mol Sci. 2022 Jul; 23(14): 7745. Published online 2022 Jul 13. doi: 10.3390/ijms23147745

PMCID:: PMC9316002

Abstract Article PDF–3.0M

Select item 83132395.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 82124346.

PEDF Gene Deletion Disrupts Corneal Innervation and Ocular Surface Function

Zhenying Shang, Chenxi Li, Xuemei Liu, Manhong Xu, Xiaomin Zhang, Xiaorong Li, Colin J. Barnstable, Shaozhen Zhao, Joyce Tombran-Tink

Invest Ophthalmol Vis Sci. 2021 Jun; 62(7): 18. Published online 2021 Jun 16. doi: 10.1167/iovs.62.7.18

PMCID:: PMC8212434

Abstract Article PDF–12M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78657668.

The Expression Levels and Cellular Localization of Pigment Epithelium Derived Factor (PEDF) in Mouse Testis: Its Possible Involvement in the Differentiation of Spermatogonial Cells

Noy Bagdadi, Alaa Sawaied, Ali AbuMadighem, Eitan Lunenfeld, Mahmoud Huleihel

Int J Mol Sci. 2021 Feb; 22(3): 1147. Published online 2021 Jan 24. doi: 10.3390/ijms22031147

PMCID:: PMC7865766

Abstract Article PDF–7.1M

Select item 75827759.

Pigment Epithelium-Derived Factor (PEDF) Fragments Prevent Mouse Cone Photoreceptor Cell Loss Induced by Focal Phototoxicity In Vivo

Francisco J. Valiente-Soriano, Johnny Di Pierdomenico, Diego García-Ayuso, Arturo Ortín-Martínez, Juan A. Miralles de Imperial-Ollero, Alejandro Gallego-Ortega, Manuel Jiménez-López, M. Paz Villegas-Pérez, S. Patricia Becerra, Manuel Vidal-Sanz

Int J Mol Sci. 2020 Oct; 21(19): 7242. Published online 2020 Sep 30. doi: 10.3390/ijms21197242

PMCID:: PMC7582775

Abstract Article PDF–1.5M

Select item 726094110.

Spatiotemporal regulation of PEDF signaling by type I collagen remodeling

Kazuki Kawahara, Takuya Yoshida, Takahiro Maruno, Hiroya Oki, Tadayasu Ohkubo, Takaki Koide, Yuji Kobayashi

Proc Natl Acad Sci U S A. 2020 May 26; 117(21): 11450–11458. Published online 2020 May 8. doi: 10.1073/pnas.2004034117

PMCID:: PMC7260941

Abstract Article PDF–1.9M

Select item 701956511.

Decreased PEDF Promotes Hepatic Fatty Acid Uptake and Lipid Droplet Formation in the Pathogenesis of NAFLD

Kuang-Tzu Huang, Kuang-Den Chen, Li-Wen Hsu, Chao-Pin Kung, Shu-Rong Li, Chien-Chih Chen, King-Wah Chiu, Shigeru Goto, Chao-Long Chen

Nutrients. 2020 Jan; 12(1): 270. Published online 2020 Jan 20. doi: 10.3390/nu12010270

PMCID:: PMC7019565

Abstract Article PDF–2.1M

Select item 691526012.

Pigment Epithelial‐Derived Factor Deficiency Accelerates Atherosclerosis Development via Promoting Endothelial Fatty Acid Uptake in Mice With Hyperlipidemia

Haiping Wang, Yanfang Yang, Ming Yang, Xinghui Li, Jing Tan, Yandi Wu, Yuling Zhang, Yuanlong Li, Bo Hu, Shijie Deng, Fengmin Yang, Saifei Gao, Hui Li, Zhenyu Yang, Hui Chen, Weibin Cai

J Am Heart Assoc. 2019 Nov 19; 8(22): e013028. Published online 2019 Nov 12. doi: 10.1161/JAHA.119.013028

PMCID:: PMC6915260

Abstract Article PDF–11M

Select item 669277013.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 653221014.

Natural killer cells and pigment epithelial-derived factor control the infiltrative and nodular growth of hepatic metastases in an Orthotopic murine model of ocular melanoma

Nyasia M. Jones, Hua Yang, Qing Zhang, Vanessa M. Morales-Tirado, Hans E. Grossniklaus

BMC Cancer. 2019; 19: 484. Published online 2019 May 22. doi: 10.1186/s12885-019-5712-3

PMCID:: PMC6532210

Abstract Article PDF–2.2M

Select item 645693315.

Obesity and High-Fat Diet Induce Distinct Changes in Placental Gene Expression and Pregnancy Outcome

Erica B Mahany, Xingfa Han, Beatriz C Borges, Sanseray da Silveira Cruz-Machado, Susan J Allen, David Garcia-Galiano, Mark J Hoenerhoff, Nicole H Bellefontaine, Carol F Elias

Endocrinology. 2018 Apr; 159(4): 1718–1733. Published online 2018 Feb 9. doi: 10.1210/en.2017-03053

PMCID:: PMC6456933

Abstract Article

Select item 638372816.

Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea

Justin Ma, Peter Lwigale

Invest Ophthalmol Vis Sci. 2019 Feb; 60(2): 661–676. doi: 10.1167/iovs.18-26018

PMCID:: PMC6383728

Abstract Article PDF–2.1M

Select item 620136317.

Polarized retinal pigment epithelium generates electrical signals that diminish with age and regulate retinal pathology

Lin Cao, Jie Liu, Jin Pu, Gillian Milne, Mei Chen, Heping Xu, Alan Shipley, John V Forrester, Colin D McCaig, Noemi Lois

J Cell Mol Med. 2018 Nov; 22(11): 5552–5564. Published online 2018 Aug 30. doi: 10.1111/jcmm.13829

PMCID:: PMC6201363

Abstract Article PDF–1.7M

Select item 609577818.

Pigment Epithelium-Derived Factor Plays a Role in Alzheimer’s Disease by Negatively Regulating Aβ42

Mao Huang, Weiwei Qi, Shuhuan Fang, Ping Jiang, Cong Yang, Yousheng Mo, Chang Dong, Yan Li, Jun Zhong, Weibin Cai, Zhonghan Yang, Ti Zhou, Qi Wang, Xia Yang, Guoquan Gao

Neurotherapeutics. 2018 Jul; 15(3): 728–741. Published online 2018 May 7. doi: 10.1007/s13311-018-0628-1

PMCID:: PMC6095778

Abstract Article PDF–5.3M

Select item 605796219.

Pigment Epithelium-Derived Factor (PEDF) as a Regulator of Wound Angiogenesis

Elizabeth R. Michalczyk, Lin Chen, David Fine, Yan Zhao, Emman Mascarinas, Paul J. Grippo, Luisa A. DiPietro

Sci Rep. 2018; 8: 11142. Published online 2018 Jul 24. doi: 10.1038/s41598-018-29465-9

PMCID:: PMC6057962

Abstract Article PDF–10M

Select item 603470820.

Matrix metalloproteinase-9 mediates the deleterious effects of α2-antiplasmin on blood brain barrier breakdown and ischemic brain injury in experimental stroke

Satish Singh, Aiilyan K. Houng, Guy L. Reed

Neuroscience. Author manuscript; available in PMC 2019 Apr 15.

Published in final edited form as: Neuroscience. 2018 Apr 15; 376: 40–47. Published online 2017 Dec 30. doi: 10.1016/j.neuroscience.2017.12.021

PMCID:: PMC6034708

Abstract Article PDF–833K

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