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Items: 1 to 20 of 29

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Acinar ATP8b1/LPC pathway promotes macrophage efferocytosis and clearance of inflammation during chronic pancreatitis development
Wan-jun Yang, Rong-chang Cao, Wang Xiao, Xiao-lou Zhang, Hao Xu, Meng Wang, Zhi-tao Zhou, Huo-ji Chen, Jia Xu, Xue-mei Chen, Jun-ling Zeng, Shu-ji Li, Min Luo, Yan-jiang Han, Xiao-bing Yang, Guo-dong Feng, Yu-heng Lu, Yuan-yuan Ni, Chan-gui Wu, Jun-jie Bai, Zi-qi Yuan, Jin Jin, Guo-wei Zhang
Cell Death Dis. 2022 Oct; 13(10): 893. Published online 2022 Oct 22. doi: 10.1038/s41419-022-05322-6
Correction in:
Cell Death Dis. 2022 Nov; 13(11): 930.
PMCID:
PMC9588032
AbstractArticlePDF–6.1M
3.
Spatio-temporal expression pattern and role of the tight junction protein MarvelD3 in pancreas development and function
Charlotte Heymans, Ophélie Delcorte, Catherine Spourquet, Mylah Villacorte-Tabelin, Sébastien Dupasquier, Younes Achouri, Siam Mahibullah, Pascale Lemoine, Maria S. Balda, Karl Matter, Christophe E. Pierreux
Sci Rep. 2021; 11: 14519. Published online 2021 Jul 15. doi: 10.1038/s41598-021-93654-2
PMCID:
PMC8282860
AbstractArticlePDF–6.6M
4.
EMC6 regulates acinar apoptosis via APAF1 in acute and chronic pancreatitis
Jie-hui Tan, Rong-chang Cao, Lei Zhou, Zhi-tao Zhou, Huo-ji Chen, Jia Xu, Xue-mei Chen, Yang-chen Jin, Jia-yu Lin, Zhao-chang Qi, Jun-ling Zeng, Shu-ji Li, Min Luo, Guo-dong Hu, Jin Jin, Guo-wei Zhang
Cell Death Dis. 2020 Nov; 11(11): 966. Published online 2020 Nov 11. doi: 10.1038/s41419-020-03177-3
PMCID:
PMC7658364
AbstractArticlePDF–5.4M
5.
Hereditary pancreatitis model by blastocyst complementation in mouse
Ayumu Asai, Masamitsu Konno, Koichi Kawamoto, Ayako Isotani, Masaki Mori, Hidetoshi Eguchi, Yuichiro Doki, Takahiro Arai, Hideshi Ishii
Oncotarget. 2020 Jun 2; 11(22): 2061–2073. Published online 2020 Jun 2. doi: 10.18632/oncotarget.27595
PMCID:
PMC7275788
AbstractArticlePDF–5.1M
6.
Mutation That Promotes Activation of Trypsinogen Increases Severity of Secretagogue-Induced Pancreatitis in Mice
Zsanett Jancsó, Miklós Sahin-Tóth
Gastroenterology. Author manuscript; available in PMC 2021 Mar 1.
Published in final edited form as: Gastroenterology. 2020 Mar; 158(4): 1083–1094. Published online 2019 Nov 18. doi: 10.1053/j.gastro.2019.11.020
PMCID:
PMC7062587
AbstractArticlePDF–2.5M
7.
ATF6 regulates the development of chronic pancreatitis by inducing p53-mediated apoptosis
Lei Zhou, Jie-hui Tan, Rong-chang Cao, Jia Xu, Xue-mei Chen, Zhao-chang Qi, Su-ying Zhou, Su-bing Li, Qi-xin Mo, Zhi-wei Li, Guo-wei Zhang
Cell Death Dis. 2019 Sep; 10(9): 662. Published online 2019 Sep 10. doi: 10.1038/s41419-019-1919-0
PMCID:
PMC6737032
AbstractArticlePDF–3.9M
8.
A Specific CNOT1 Mutation Results in a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development
Elisa De Franco, Rachel A. Watson, Wolfgang J. Weninger, Chi C. Wong, Sarah E. Flanagan, Richard Caswell, Angela Green, Catherine Tudor, Christopher J. Lelliott, Stefan H. Geyer, Barbara Maurer-Gesek, Lukas F. Reissig, Hana Lango Allen, Almuth Caliebe, Reiner Siebert, Paul Martin Holterhus, Asma Deeb, Fabrice Prin, Robert Hilbrands, Harry Heimberg, Sian Ellard, Andrew T. Hattersley, Inês Barroso
Am J Hum Genet. 2019 May 2; 104(5): 985–989. Published online 2019 Apr 18. doi: 10.1016/j.ajhg.2019.03.018
PMCID:
PMC6506862
AbstractArticlePDF–1.2M
9.
A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies
David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury
Nat Genet. Author manuscript; available in PMC 2018 Aug 19.
Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7
PMCID:
PMC5862771
AbstractArticlePDF–2.5M
10.
An N-terminal motif unique to primate tau enables differential protein–protein interactions
Kristie Stefanoska, Alexander Volkerling, Josefine Bertz, Anne Poljak, Yazi D. Ke, Lars M. Ittner, Arne Ittner
J Biol Chem. 2018 Mar 9; 293(10): 3710–3719. Published online 2018 Jan 30. doi: 10.1074/jbc.RA118.001784
PMCID:
PMC5846163
AbstractArticlePDF–1.2M
11.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
12.
Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression
Alexandra Naba, Karl R. Clauser, D. R. Mani, Steven A. Carr, Richard O. Hynes
Sci Rep. 2017; 7: 40495. Published online 2017 Jan 10. doi: 10.1038/srep40495
PMCID:
PMC5223159
AbstractArticlePDF–2.3M
13.
Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis
Sebastian Gaiser, Jaroslaw Daniluk, Yan Liu, Lilian Tsou, Jun Chu, Woojin Lee, Daniel S Longnecker, Craig D Logsdon, Baoan Ji
Gut. Author manuscript; available in PMC 2015 Jan 23.
Published in final edited form as: Gut. 2011 Oct; 60(10): 1379–1388. Published online 2011 Apr 6. doi: 10.1136/gut.2010.226175
PMCID:
PMC4304390
AbstractArticlePDF–3.9M
14.
Mesotrypsin and Caspase-14 Participate in Prosaposin Processing: POTENTIAL RELEVANCE TO EPIDERMAL PERMEABILITY BARRIER FORMATION
Mami Yamamoto-Tanaka, Akira Motoyama, Masashi Miyai, Yukiko Matsunaga, Junko Matsuda, Ryoji Tsuboi, Toshihiko Hibino
J Biol Chem. 2014 Jul 18; 289(29): 20026–20038. Published online 2014 May 28. doi: 10.1074/jbc.M113.543421
PMCID:
PMC4106320
AbstractArticlePDF–3.0M
15.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
16.
Dysregulation of Protease and Protease Inhibitors in a Mouse Model of Human Pelvic Organ Prolapse
Madhusudhan Budatha, Simone Silva, Teodoro Ignacio Montoya, Ayako Suzuki, Sheena Shah-Simpson, Cecilia Karin Wieslander, Masashi Yanagisawa, Ruth Ann Word, Hiromi Yanagisawa
PLoS One. 2013; 8(2): e56376. Published online 2013 Feb 20. doi: 10.1371/journal.pone.0056376
PMCID:
PMC3577807
AbstractArticlePDF–1.1M
17.
Mapping the Nephronophthisis-Joubert-Meckel-Gruber Protein Network Reveals Ciliopathy Disease Genes and Pathways
Liyun Sang, Julie J. Miller, Kevin C. Corbit, Rachel H. Giles, Matthew J. Brauer, Edgar A. Otto, Lisa M. Baye, Xiaohui Wen, Suzie J. Scales, Mandy Kwong, Erik G. Huntzicker, Mindan K. Sfakianos, Wendy Sandoval, J. Fernando Bazan, Priya Kulkarni, Francesc R. Garcia-Gonzalo, Allen D. Seol, John F. O'Toole, Susanne Held, Heiko M. Reutter, William S. Lane, Muhammad Arshad Rafiq, Abdul Noor, Muhammad Ansar, Akella Radha Rama Devi, Val C. Sheffield, Diane C. Slusarski, John B. Vincent, Daniel A. Doherty, Friedhelm Hildebrandt, Jeremy F. Reiter, Peter K. Jackson
Cell. Author manuscript; available in PMC 2012 Jun 26.
Published in final edited form as: Cell. 2011 May 13; 145(4): 513–528. doi: 10.1016/j.cell.2011.04.019
PMCID:
PMC3383065
AbstractArticlePDF–2.0M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Up-regulation of ectopic trypsins in the myocardium by influenza A virus infection triggers acute myocarditis
Hai-Yan Pan, Hirotsugu Yamada, Junji Chida, Siye Wang, Mihiro Yano, Min Yao, Jianhua Zhu, Hiroshi Kido
Cardiovasc Res. 2011 Feb 15; 89(3): 595–603. Published online 2010 Nov 16. doi: 10.1093/cvr/cvq358
PMCID:
PMC3028976
AbstractArticlePDF–594K
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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