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Select item 93460021.

PILRA polymorphism modifies the effect of APOE4 and GM17 on Alzheimer’s disease risk

Karin Lopatko Lindman, Caroline Jonsson, Bodil Weidung, Jan Olsson, Janardan P. Pandey, Dmitry Prokopenko, Rudolph E. Tanzi, Göran Hallmans, Sture Eriksson, Fredrik Elgh, Hugo Lövheim

Sci Rep. 2022; 12: 13264. Published online 2022 Aug 2. doi: 10.1038/s41598-022-17058-6

PMCID:: PMC9346002

Abstract Article PDF–1.1M

Select item 90591702.

Inhibitory Fcγ Receptor and Paired Immunoglobulin Type 2 Receptor Alpha Genotypes in Alzheimer’s Disease

Janardan P. Pandey, Aryan M. Namboodiri, Paul J. Nietert, Lisa L. Barnes, David A. Bennett

J Alzheimers Dis. Author manuscript; available in PMC 2022 May 2.

Published in final edited form as: J Alzheimers Dis. 2021; 84(3): 965–968. doi: 10.3233/JAD-215174

PMCID:: PMC9059170

Abstract Article PDF–302K

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 73220674.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 71699835.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 62354026.

Paired Immunoglobulin-like Type 2 Receptor Alpha G78R variant alters ligand binding and confers protection to Alzheimer's disease

Nisha Rathore, Sree Ranjani Ramani, Homer Pantua, Jian Payandeh, Tushar Bhangale, Arthur Wuster, Manav Kapoor, Yonglian Sun, Sharookh B. Kapadia, Lino Gonzalez, Ali A. Zarrin, Alison Goate, David V. Hansen, Timothy W. Behrens, Robert R. Graham

PLoS Genet. 2018 Nov; 14(11): e1007427. Published online 2018 Nov 2. doi: 10.1371/journal.pgen.1007427

PMCID:: PMC6235402

Abstract Article PDF–2.5M

Select item 60057347.

Whole-exome sequencing of the BDR cohort: evidence to support the role of the PILRA gene in Alzheimer’s disease

T. Patel, K. J. Brookes, J. Turton, S. Chaudhury, T. Guetta-Baranes, R. Guerreiro, J. Bras, D. Hernandez, A. Singleton, P. T. Francis, J. Hardy, K. Morgan

Neuropathol Appl Neurobiol. Author manuscript; available in PMC 2019 Mar 28.

Published in final edited form as: Neuropathol Appl Neurobiol. 2018 Aug; 44(5): 506–521. Published online 2018 Jan 7. doi: 10.1111/nan.12452

PMCID:: PMC6005734

Abstract Article PDF–405K

Select item 57430858.

Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILRα immune cell receptor

Atsushi Furukawa, Kosuke Kakita, Tomoki Yamada, Mikihiro Ishizuka, Jiro Sakamoto, Nanao Hatori, Naoyoshi Maeda, Fumina Ohsaka, Takashi Saitoh, Takao Nomura, Kimiko Kuroki, Hisanori Nambu, Hisashi Arase, Shigeki Matsunaga, Masahiro Anada, Toyoyuki Ose, Shunichi Hashimoto, Katsumi Maenaka

J Biol Chem. 2017 Dec 22; 292(51): 21128–21136. Published online 2017 Oct 18. doi: 10.1074/jbc.M117.799239

PMCID:: PMC5743085

Abstract Article PDF–1.7M

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 517303410.

PILRα binds an unknown receptor expressed primarily on CD56^bright and decidual-NK cells and activates NK cell functions

Yael Ophir, Alexandra Duev-Cohen, Rachel Yamin, Pini Tsukerman, Yoav Bauman, Moriya Gamliel, Ofer Mandelboim

Oncotarget. 2016 Jul 5; 7(27): 40953–40964. Published online 2016 Mar 27. doi: 10.18632/oncotarget.8397

PMCID:: PMC5173034

Abstract Article PDF–995K

Select item 461721111.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 408986512.

PANP is a novel O-glycosylated PILRα ligand expressed in neural tissues

Amane Kogure, Ikuo Shiratori, Jing Wang, Lewis L. Lanier, Hisashi Arase

Biochem Biophys Res Commun. Author manuscript; available in PMC 2014 Jul 9.

Published in final edited form as: Biochem Biophys Res Commun. 2011 Feb 18; 405(3): 428–433. Published online 2011 Jan 15. doi: 10.1016/j.bbrc.2011.01.047

PMCID:: PMC4089865

Abstract Article PDF–723K

Select item 406649413.

Structural basis for simultaneous recognition of an O-glycan and its attached peptide of mucin family by immune receptor PILRα

Kimiko Kuroki, Jing Wang, Toyoyuki Ose, Munechika Yamaguchi, Shigekazu Tabata, Nobuo Maita, Seiko Nakamura, Mizuho Kajikawa, Amane Kogure, Takeshi Satoh, Hisashi Arase, Katsumi Maenaka

Proc Natl Acad Sci U S A. 2014 Jun 17; 111(24): 8877–8882. Published online 2014 Jun 2. doi: 10.1073/pnas.1324105111

PMCID:: PMC4066494

Abstract Article PDF–1.1M

Select item 405056714.

PILRα and PILRβ have a siglec fold and provide the basis of binding to sialic acid

Qiong Lu, Guangwen Lu, Jianxun Qi, Han Wang, Yifang Xuan, Qihui Wang, Yan Li, Yanfang Zhang, Chunfu Zheng, Zheng Fan, Jinghua Yan, George F. Gao

Proc Natl Acad Sci U S A. 2014 Jun 3; 111(22): 8221–8226. Published online 2014 May 19. doi: 10.1073/pnas.1320716111

PMCID:: PMC4050567

Abstract Article PDF–1.0M

Select item 359215415.

The Amino Terminus of Herpes Simplex Virus 1 Glycoprotein K Is Required for Virion Entry via the Paired Immunoglobulin-Like Type-2 Receptor Alpha

Sona Chowdhury, Vladimir N. Chouljenko, Misagh Naderi, Konstantin G. Kousoulas

J Virol. 2013 Mar; 87(6): 3305–3313. doi: 10.1128/JVI.02982-12

PMCID:: PMC3592154

Abstract Article PDF–2.7M

Select item 340299016.

Amino acid differences in glycoproteins B (gB), C (gC), H (gH) and L(gL) are associated with enhanced herpes simplex virus type-1 (McKrae) entry via the paired immunoglobulin-like type-2 receptor α

Sona Chowdhury, Misagh Naderi, Vladimir N Chouljenko, Jason D Walker, Konstantin G Kousoulas

Virol J. 2012; 9: 112. Published online 2012 Jun 13. doi: 10.1186/1743-422X-9-112

PMCID:: PMC3402990

Abstract Article PDF–1.0M

Select item 334607117.

Evolutionarily Conserved Paired Immunoglobulin-like Receptor α (PILRα) Domain Mediates Its Interaction with Diverse Sialylated Ligands

Yonglian Sun, Kate Senger, Tomasz K. Baginski, Anita Mazloom, Yvonne Chinn, Homer Pantua, Kajal Hamidzadeh, Sree Ranjani Ramani, Elizabeth Luis, Irene Tom, Andrew Sebrell, Gabriel Quinones, Yan Ma, Kiran Mukhyala, Tao Sai, Jiabing Ding, Benjamin Haley, Hooman Shadnia, Sharookh B. Kapadia, Lino C. Gonzalez, Philip E. Hass, Ali A. Zarrin

J Biol Chem. 2012 May 4; 287(19): 15837–15850. Published online 2012 Mar 6. doi: 10.1074/jbc.M111.286633

PMCID:: PMC3346071

Abstract Article PDF–2.4M

Select item 326170818.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67

Correction in:: Mol Syst Biol. 2017 Dec; 13(12): 965.

PMCID:: PMC3261708

Abstract Article PDF–2.0M

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 288296120.

Human Chromosome 7: DNA Sequence and Biology

Stephen W. Scherer, Joseph Cheung, Jeffrey R. MacDonald, Lucy R. Osborne, Kazuhiko Nakabayashi, Jo-Anne Herbrick, Andrew R. Carson, Layla Parker-Katiraee, Jennifer Skaug, Razi Khaja, Junjun Zhang, Alexander K. Hudek, Martin Li, May Haddad, Gavin E. Duggan, Bridget A. Fernandez, Emiko Kanematsu, Simone Gentles, Constantine C. Christopoulos, Sanaa Choufani, Dorota Kwasnicka, Xiangqun H. Zheng, Zhongwu Lai, Deborah Nusskern, Qing Zhang, Zhiping Gu, Fu Lu, Susan Zeesman, Malgorzata J. Nowaczyk, Ikuko Teshima, David Chitayat, Cheryl Shuman, Rosanna Weksberg, Elaine H. Zackai, Theresa A. Grebe, Sarah R. Cox, Susan J. Kirkpatrick, Nazneen Rahman, Jan M. Friedman, Henry H. Q. Heng, Pier Giuseppe Pelicci, Francesco Lo-Coco, Elena Belloni, Lisa G. Shaffer, Barbara Pober, Cynthia C. Morton, James F. Gusella, Gail A. P. Bruns, Bruce R. Korf, Bradley J. Quade, Azra H. Ligon, Heather Ferguson, Anne W. Higgins, Natalia T. Leach, Steven R. Herrick, Emmanuelle Lemyre, Chantal G. Farra, Hyung-Goo Kim, Anne M. Summers, Karen W. Gripp, Wendy Roberts, Peter Szatmari, Elizabeth J. T. Winsor, Karl-Heinz Grzeschik, Ahmed Teebi, Berge A. Minassian, Juha Kere, Lluis Armengol, Miguel Angel Pujana, Xavier Estivill, Michael D. Wilson, Ben F. Koop, Sabrina Tosi, Gudrun E. Moore, Andrew P. Boright, Eitan Zlotorynski, Batsheva Kerem, Peter M. Kroisel, Erwin Petek, David G. Oscier, Sarah J. Mould, Hartmut Döhner, Konstanze Döhner, Johanna M. Rommens, John B. Vincent, J. Craig Venter, Peter W. Li, Richard J. Mural, Mark D. Adams, Lap-Chee Tsui

Science. Author manuscript; available in PMC 2010 Jun 9.

Published in final edited form as: Science. 2003 May 2; 300(5620): 767–772. Published online 2003 Apr 10. doi: 10.1126/science.1083423