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Items: 1 to 20 of 23

1.
HILPDA promotes NASH-driven HCC development by restraining intracellular fatty acid flux in hypoxia
Davide Povero, Yongbin Chen, Scott M. Johnson, Cailin E. McMahon, Meixia Pan, Hanmei Bao, Xuan-Mai T. Petterson, Emily Blake, Kimberly P. Lauer, Daniel R. O’Brien, Yue Yu, Rondell P. Graham, Timucin Taner, Xianlin Han, Gina L. Razidlo, Jun Liu
J Hepatol. Author manuscript; available in PMC 2024 Jul 11.
Published in final edited form as: J Hepatol. 2023 Aug; 79(2): 378–393. Published online 2023 Apr 13. doi: 10.1016/j.jhep.2023.03.041
PMCID:
PMC11238876
AbstractArticlePDF–3.6M
2.
Hypoxia, Hypoxia-Inducible Gene 2 (HIG2)/HILPDA, and Intracellular Lipolysis in Cancer
Davide Povero, Scott M. Johnson, Jun Liu
Cancer Lett. Author manuscript; available in PMC 2024 Jul 2.
Published in final edited form as: Cancer Lett. 2020 Nov 28; 493: 71–79. Published online 2020 Aug 18. doi: 10.1016/j.canlet.2020.06.013
PMCID:
PMC11218043
AbstractArticlePDF–770K
3.
HILPDA-mediated lipidomic remodelling promotes radiotherapy resistance in nasopharyngeal carcinoma by accelerating mitophagy
Yue Zhang, Chen Pang, Chi Zhang, Yijie Wang, Peng Wang, Yanrong Chen, Junyi Wang, Ying Hu, Chengxiang Liu, Houjie Liang, Ganfeng Xie, Juanjuan Ou
Cell Mol Life Sci. 2023 Sep; 80(9): 242. Published online 2023 Aug 8. doi: 10.1007/s00018-023-04891-9
PMCID:
PMC11072511
AbstractArticlePDF–21M
4.
Targeting MYC induces lipid droplet accumulation by upregulation of HILPDA in clear cell renal cell carcinoma
Lourdes Sainero-Alcolado, Elisa Garde-Lapido, Marteinn Thor Snaebjörnsson, Sarah Schoch, Irene Stevens, María Victoria Ruiz-Pérez, Christine Dyrager, Vicent Pelechano, Håkan Axelson, Almut Schulze, Marie Arsenian-Henriksson
Proc Natl Acad Sci U S A. 2024 Feb 13; 121(7): e2310479121. Published online 2024 Feb 9. doi: 10.1073/pnas.2310479121
PMCID:
PMC10873620
AbstractArticlePDF–10M
5.
HILPDA regulates lipid metabolism, lipid droplet abundance, and response to microenvironmental stress in solid tumors.
Matthew J. VandeKopple, Jinghai Wu, Erich N. Auer, Amato J. Giaccia, Nicholas C. Denko, Ioanna Papandreou
Mol Cancer Res. Author manuscript; available in PMC 2020 Apr 1.
Published in final edited form as: Mol Cancer Res. 2019 Oct; 17(10): 2089–2101. Published online 2019 Jul 15. doi: 10.1158/1541-7786.MCR-18-1343
PMCID:
PMC6774878
AbstractArticlePDF–2.2M
6.
Hypoxia-inducible gene 2 promotes the immune escape of hepatocellular carcinoma from nature killer cells through the interleukin-10-STAT3 signaling pathway
Chuanbao Cui, Kaiwen Fu, Lu Yang, Shuzhi Wu, Zuojie Cen, Xingxing Meng, Qiongguang Huang, Zhichun Xie
J Exp Clin Cancer Res. 2019; 38: 229. Published online 2019 May 29. doi: 10.1186/s13046-019-1233-9
PMCID:
PMC6542136
AbstractArticlePDF–9.4M
7.
Key Genes of Lipid Metabolism and WNT-Signaling Are Downregulated in Subcutaneous Adipose Tissue with Moderate Weight Loss
Ruth Schübel, Disorn Sookthai, Judith Greimel, Theron S. Johnson, Mirja E. Grafetstätter, Romy Kirsten, Mario Kratz, Cornelia M. Ulrich, Rudolf Kaaks, Tilman Kühn
Nutrients. 2019 Mar; 11(3): 639. Published online 2019 Mar 16. doi: 10.3390/nu11030639
PMCID:
PMC6471921
AbstractArticlePDF–1.7M
8.
A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis
Yilong Zou, Michael J. Palte, Amy A. Deik, Haoxin Li, John K. Eaton, Wenyu Wang, Yuen-Yi Tseng, Rebecca Deasy, Maria Kost-Alimova, Vlado Dančík, Elizaveta S. Leshchiner, Vasanthi S. Viswanathan, Sabina Signoretti, Toni K. Choueiri, Jesse S. Boehm, Bridget K. Wagner, John G. Doench, Clary B. Clish, Paul A. Clemons, Stuart L. Schreiber
Nat Commun. 2019; 10: 1617. Published online 2019 Apr 8. doi: 10.1038/s41467-019-09277-9
PMCID:
PMC6453886
AbstractArticlePDF–2.2M
9.
Hypoxia-inducible lipid droplet-associated protein inhibits adipose triglyceride lipase
Krishna M. Padmanabha Das, Lisa Wechselberger, Márton Liziczai, Montserrat De la Rosa Rodriguez, Gernot F. Grabner, Christoph Heier, Roland Viertlmayr, Claudia Radler, Jörg Lichtenegger, Robert Zimmermann, Jan Willem Borst, Rudolf Zechner, Sander Kersten, Monika Oberer
J Lipid Res. 2018 Mar; 59(3): 531–541. Published online 2018 Jan 11. doi: 10.1194/jlr.M082388
PMCID:
PMC5832925
AbstractArticlePDF–1.2M
10.
Systematic protein–protein interaction mapping for clinically relevant human GPCRs
Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar
Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430
PMCID:
PMC5371730
AbstractArticlePDF–4.1M
11.
Hypoxia upregulates HIG2 expression and contributes to bevacizumab resistance in glioblastoma
Xing-gang Mao, Chao Wang, Dong-ye Liu, Xiang Zhang, Liang Wang, Ming Yan, Wei Zhang, Jun Zhu, Zi-chao Li, Chen Mi, Jing-yang Tian, Guang-dong Hou, Si-yu Miao, Zi-xuan Song, Jin-cheng Li, Xiao-yan Xue
Oncotarget. 2016 Jul 26; 7(30): 47808–47820. Published online 2016 Jun 14. doi: 10.18632/oncotarget.10029
PMCID:
PMC5216980
AbstractArticlePDF–3.5M
12.
High-throughput analyses of hnRNP H1 dissects its multi-functional aspect
Philip J. Uren, Emad Bahrami-Samani, Patricia Rosa de Araujo, Christine Vogel, Mei Qiao, Suzanne C. Burns, Andrew D. Smith, Luiz O. F. Penalva
RNA Biol. 2016 Apr; 13(4): 400–411. Published online 2016 Jan 13. doi: 10.1080/15476286.2015.1138030
PMCID:
PMC4841607
AbstractArticlePDF–1.6M
13.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
14.
Hypoxia-inducible Lipid Droplet-associated (HILPDA) Is a Novel Peroxisome Proliferator-activated Receptor (PPAR) Target Involved in Hepatic Triglyceride Secretion
Frits Mattijssen, Anastasia Georgiadi, Tresty Andasarie, Ewa Szalowska, Annika Zota, Anja Krones-Herzig, Christoph Heier, Dariusz Ratman, Karolien De Bosscher, Ling Qi, Rudolf Zechner, Stephan Herzig, Sander Kersten
J Biol Chem. 2014 Jul 11; 289(28): 19279–19293. Published online 2014 May 29. doi: 10.1074/jbc.M114.570044
PMCID:
PMC4094041
AbstractArticlePDF–3.3M
15.
HIG2 promotes colorectal cancer progression via hypoxia-dependent and independent pathways
Sun-Hee Kim, Dingzhi Wang, Yun-Yong Park, Hiroshi Katoh, Ofer Margalit, Michal Sheffer, Hong Wu, Vijaykumar R. Holla, Ju-Seog Lee, Raymond N. DuBois
Cancer Lett. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Cancer Lett. 2013 Dec 1; 341(2): 159–165. Published online 2013 Aug 2. doi: 10.1016/j.canlet.2013.07.028
PMCID:
PMC3928010
AbstractArticlePDF–1.0M
16.
Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein
Tory P. Johnson, Karan Patel, Kory R. Johnson, Dragan Maric, Peter A. Calabresi, Rodrigo Hasbun, Avindra Nath
Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33): 13588–13593. Published online 2013 Jul 29. doi: 10.1073/pnas.1308673110
PMCID:
PMC3746932
AbstractArticlePDF–1002K
17.
Image-Based Genome-Wide siRNA Screen Identifies Selective Autophagy Factors
Anthony Orvedahl, Rhea Sumpter, Jr., Guanghua Xiao, Aylwin Ng, Zhongju Zou, Yi Tang, Masahiro Narimatsu, Christopher Gilpin, Qihua Sun, Michael Roth, Christian V. Forst, Jeffrey L. Wrana, Ying E. Zhang, Katherine Luby-Phelps, Ramnik Xavier, Yang Xie, Beth Levine
Nature. Author manuscript; available in PMC 2012 Jun 1.
Published in final edited form as: Nature. 2011 Dec 1; 480(7375): 113–117. doi: 10.1038/nature10546
PMCID:
PMC3229641
AbstractArticlePDF–2.3M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Gene Expression Profiling and Chromatin Immunoprecipitation Identify DBN1, SETMAR and HIG2 as Direct Targets of SOX11 in Mantle Cell Lymphoma
Xiao Wang, Stefan Björklund, Agata M. Wasik, Alf Grandien, Patrik Andersson, Eva Kimby, Karin Dahlman-Wright, Chunyan Zhao, Birger Christensson, Birgitta Sander
PLoS One. 2010; 5(11): e14085. Published online 2010 Nov 22. doi: 10.1371/journal.pone.0014085
PMCID:
PMC2989913
AbstractArticlePDF–309K
20.
Human Chromosome 7: DNA Sequence and Biology
Stephen W. Scherer, Joseph Cheung, Jeffrey R. MacDonald, Lucy R. Osborne, Kazuhiko Nakabayashi, Jo-Anne Herbrick, Andrew R. Carson, Layla Parker-Katiraee, Jennifer Skaug, Razi Khaja, Junjun Zhang, Alexander K. Hudek, Martin Li, May Haddad, Gavin E. Duggan, Bridget A. Fernandez, Emiko Kanematsu, Simone Gentles, Constantine C. Christopoulos, Sanaa Choufani, Dorota Kwasnicka, Xiangqun H. Zheng, Zhongwu Lai, Deborah Nusskern, Qing Zhang, Zhiping Gu, Fu Lu, Susan Zeesman, Malgorzata J. Nowaczyk, Ikuko Teshima, David Chitayat, Cheryl Shuman, Rosanna Weksberg, Elaine H. Zackai, Theresa A. Grebe, Sarah R. Cox, Susan J. Kirkpatrick, Nazneen Rahman, Jan M. Friedman, Henry H. Q. Heng, Pier Giuseppe Pelicci, Francesco Lo-Coco, Elena Belloni, Lisa G. Shaffer, Barbara Pober, Cynthia C. Morton, James F. Gusella, Gail A. P. Bruns, Bruce R. Korf, Bradley J. Quade, Azra H. Ligon, Heather Ferguson, Anne W. Higgins, Natalia T. Leach, Steven R. Herrick, Emmanuelle Lemyre, Chantal G. Farra, Hyung-Goo Kim, Anne M. Summers, Karen W. Gripp, Wendy Roberts, Peter Szatmari, Elizabeth J. T. Winsor, Karl-Heinz Grzeschik, Ahmed Teebi, Berge A. Minassian, Juha Kere, Lluis Armengol, Miguel Angel Pujana, Xavier Estivill, Michael D. Wilson, Ben F. Koop, Sabrina Tosi, Gudrun E. Moore, Andrew P. Boright, Eitan Zlotorynski, Batsheva Kerem, Peter M. Kroisel, Erwin Petek, David G. Oscier, Sarah J. Mould, Hartmut Döhner, Konstanze Döhner, Johanna M. Rommens, John B. Vincent, J. Craig Venter, Peter W. Li, Richard J. Mural, Mark D. Adams, Lap-Chee Tsui
Science. Author manuscript; available in PMC 2010 Jun 9.
Published in final edited form as: Science. 2003 May 2; 300(5620): 767–772. Published online 2003 Apr 10. doi: 10.1126/science.1083423
PMCID:
PMC2882961
AbstractArticlePDF–1.2M

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