PMC Links for GEO Profiles (Select 108370057) - PMC

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79489644.

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1

Lee D. Harris, Janic Le Pen, Nico Scholz, Juliusz Mieszczanek, Natalie Vaughan, Simon Davis, Georgina Berridge, Benedikt M. Kessler, Mariann Bienz, Julien D.F. Licchesi

J Biol Chem. 2021 Jan-Jun; 296: 100246. Published online 2021 Jan 8. doi: 10.1074/jbc.RA120.015162

PMCID:: PMC7948964

Abstract Article PDF–2.7M

Select item 77588365.

USP15 deubiquitinates CARD9 to downregulate C-type lectin receptor-mediated signaling

Wenting Xu, Jason S. Rush, Daniel B. Graham, Zhifang Cao, Ramnik J. Xavier

Immunohorizons. Author manuscript; available in PMC 2020 Dec 24.

Published in final edited form as: Immunohorizons. 2020 Oct 22; 4(10): 670–678. Published online 2020 Oct 22. doi: 10.4049/immunohorizons.2000036

PMCID:: PMC7758836

Abstract Article PDF–801K

Select item 71699836.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 56645027.

Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease

Elizaveta S. Leshchiner, Jason S. Rush, Michael A. Durney, Zhifang Cao, Vlado Dančík, Benjamin Chittick, Huixian Wu, Adam Petrone, Joshua A. Bittker, Andrew Phillips, Jose R. Perez, Alykhan F. Shamji, Virendar K. Kaushik, Mark J. Daly, Daniel B. Graham, Stuart L. Schreiber, Ramnik J. Xavier

Proc Natl Acad Sci U S A. 2017 Oct 24; 114(43): 11392–11397. Published online 2017 Oct 9. doi: 10.1073/pnas.1705748114

PMCID:: PMC5664502

Abstract Article PDF–1.3M

Select item 55316118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 50893749.

A dynamic protein interaction landscape of the human centrosome-cilium interface

Gagan D. Gupta, Étienne Coyaud, João Gonçalves, Bahareh A. Mojarad, Yi Liu, Qianzhu Wu, Ladan Gheiratmand, David Comartin, Johnny M. Tkach, Sally W.T. Cheung, Mikhail Bashkurov, Monica Hasegan, James D. Knight, Zhen-Yuan Lin, Markus Schueler, Friedhelm Hildebrandt, Jason Moffat, Anne-Claude Gingras, Brian Raught, Laurence Pelletier

Cell. Author manuscript; available in PMC 2016 Dec 3.

Published in final edited form as: Cell. 2015 Dec 3; 163(6): 1484–1499. doi: 10.1016/j.cell.2015.10.065

PMCID:: PMC5089374

Abstract Article PDF–1.5M

Select item 508441610.

Tripartite motif containing 62 is a novel prognostic marker and suppresses tumor metastasis via c-Jun/Slug signaling-mediated epithelial-mesenchymal transition in cervical cancer

Tian-Yu Liu, Jian Chen, Chun-Liang Shang, Hong-Wei Shen, Jia-Ming Huang, Yan-Chun Liang, Wei Wang, Yun-He Zhao, Duo Liu, Man Shu, Lu-Yan Guo, Zheng Hu, Shu-Zhong Yao

J Exp Clin Cancer Res. 2016; 35: 170. Published online 2016 Oct 28. doi: 10.1186/s13046-016-0445-5

PMCID:: PMC5084416

Abstract Article PDF–5.8M

Select item 467273311.

The Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-Fungal Immunity and Intestinal Inflammation

Zhifang Cao, Kara L. Conway, Robert J. Heath, Jason S. Rush, Elizaveta S. Leshchiner, Zaida G. Ramirez-Ortez, Natalia B. Nedelsky, Hailiang Huang, Aylwin Ng, Agnès Gardet, Shih-Chin Cheng, Alykhan F. Shamji, John D. Rioux, Cisca Wijmenga, Mihai G. Netea, Terry K. Means, Mark J. Daly, Ramnik J. Xavier

Immunity. Author manuscript; available in PMC 2016 Oct 20.

Published in final edited form as: Immunity. 2015 Oct 20; 43(4): 715–726. doi: 10.1016/j.immuni.2015.10.005

PMCID:: PMC4672733

Abstract Article PDF–1.5M

Select item 461721112.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 456025513.

Loss of TRIM62 Expression Is an Independent Adverse Prognostic Factor in Acute Myeloid Leukemia

Alfonso Quintás-Cardama, Nianxiang Zhang, Yi Hua Qiu, Sean Post, Chad J. Creighton, Jorge Cortes, Kevin R. Coombes, Steven M. Kornblau

Clin Lymphoma Myeloma Leuk. Author manuscript; available in PMC 2015 Sep 4.

Published in final edited form as: Clin Lymphoma Myeloma Leuk. 2015 Feb; 15(2): 115–127.e15. Published online 2014 Aug 12. doi: 10.1016/j.clml.2014.07.011

PMCID:: PMC4560255

Abstract Article PDF–1.4M

Select item 421426714.

DEAR1, a Novel Tumor Suppressor that Regulates Cell Polarity and Epithelial Plasticity

Nanyue Chen, Seetharaman Balasenthil, Jacquelyn Reuther, Ann McNeill Killary

Cancer Res. Author manuscript; available in PMC 2015 Oct 15.

Published in final edited form as: Cancer Res. 2014 Oct 15; 74(20): 5683–5689. Published online 2014 Sep 26. doi: 10.1158/0008-5472.CAN-14-1171

PMCID:: PMC4214267

Abstract Article PDF–995K

Select item 410792715.

DEAR1 is a Chromosome 1p35 Tumor Suppressor and Master Regulator of TGFβ-Driven Epithelial-Mesenchymal Transition

Nanyue Chen, Seetharaman Balasenthil, Jacquelyn Reuther, Aileen Frayna, Ying Wang, Dawn S. Chandler, Lynne V. Abruzzo, Asif Rashid, Jaime Rodriguez, Guillermina Lozano, Yu Cao, Erica Lokken, Jinyun Chen, Marsha L. Frazier, Aysegul A. Sahin, Ignacio I. Wistuba, Subrata Sen, Steven T. Lott, Ann McNeill Killary

Cancer Discov. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Cancer Discov. 2013 Oct; 3(10): 1172–1189. Published online 2013 Jul 9. doi: 10.1158/2159-8290.CD-12-0499

PMCID:: PMC4107927

Abstract Article PDF–3.4M

Select item 353641816.

TRIM Protein-Mediated Regulation of Inflammatory and Innate Immune Signaling and Its Association with Antiretroviral Activity

Pradeep D. Uchil, Angelika Hinz, Steven Siegel, Anna Coenen-Stass, Thomas Pertel, Jeremy Luban, Walther Mothes

J Virol. 2013 Jan; 87(1): 257–272. doi: 10.1128/JVI.01804-12

PMCID:: PMC3536418

Abstract Article PDF–3.8M

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 289646418.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

Select item 267304219.

DEAR1 Is a Dominant Regulator of Acinar Morphogenesis and an Independent Predictor of Local Recurrence-Free Survival in Early-Onset Breast Cancer

Steven T. Lott, Nanyue Chen, Dawn S. Chandler, Qifeng Yang, Luo Wang, Marivonne Rodriguez, Hongyan Xie, Seetharaman Balasenthil, Thomas A. Buchholz, Aysegul A. Sahin, Katrina Chaung, Baili Zhang, Shodimu-Emmanu Olufemi, Jinyun Chen, Henry Adams, Vimla Band, Adel K. El-Naggar, Marsha L. Frazier, Khandan Keyomarsi, Kelly K. Hunt, Subrata Sen, Bruce Haffty, Stephen M. Hewitt, Ralf Krahe, Ann McNeill Killary

PLoS Med. 2009 May; 6(5): e1000068. Published online 2009 May 5. doi: 10.1371/journal.pmed.1000068

PMCID:: PMC2673042

Abstract Article PDF–4.3M

Select item 266971320.

A New Tumor Suppressor That Regulates Tissue Architecture

Senthil K. Muthuswamy

PLoS Med. 2009 May; 6(5): e1000073. Published online 2009 May 5. doi: 10.1371/journal.pmed.1000073

PMCID:: PMC2669713

Article PDF–72K

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