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Items: 1 to 20 of 27

1.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
2.
Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma
Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li
Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x
PMCID:
PMC9950447
AbstractArticlePDF–8.4M
3.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
4.
Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology
Nikhil J. Pandya, Congwei Wang, Veronica Costa, Paul Lopatta, Sonja Meier, F. Isabella Zampeta, A. Mattijs Punt, Edwin Mientjes, Philip Grossen, Tania Distler, Manuel Tzouros, Yasmina Martí, Balazs Banfai, Christoph Patsch, Soren Rasmussen, Marius Hoener, Marco Berrera, Thomas Kremer, Tom Dunkley, Martin Ebeling, Ben Distel, Ype Elgersma, Ravi Jagasia
Cell Rep Med. 2021 Aug 17; 2(8): 100360. Published online 2021 Aug 17. doi: 10.1016/j.xcrm.2021.100360
PMCID:
PMC8385294
AbstractArticlePDF–4.5M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2
Fei Xu, Jiajia Li, Mengdong Ni, Jingyi Cheng, Haiyun Zhao, Shanshan Wang, Xiang Zhou, Xiaohua Wu
Mol Cancer. 2021; 20: 45. Published online 2021 Mar 3. doi: 10.1186/s12943-021-01340-8
PMCID:
PMC7927415
AbstractArticlePDF–2.9M
7.
LncRNAs-directed PTEN enzymatic switch governs epithelial–mesenchymal transition
Qingsong Hu, Chunlai Li, Shouyu Wang, Yajuan Li, Bo Wen, Yanyan Zhang, Ke Liang, Jun Yao, Youqiong Ye, Heidi Hsiao, Tina K. Nguyen, Peter K. Park, Sergey D. Egranov, David H. Hawke, Jeffrey R. Marks, Leng Han, Mien-Chie Hung, Bing Zhang, Chunru Lin, Liuqing Yang
Cell Res. 2019 Apr; 29(4): 286–304. Published online 2019 Jan 10. doi: 10.1038/s41422-018-0134-3
PMCID:
PMC6461864
AbstractArticlePDF–11M
8.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
9.
SRGAP1, a crucial target of miR-340 and miR-124, functions as a potential oncogene in gastric tumorigenesis
Tingting Huang, Yuhang Zhou, Jinglin Zhang, Chi Chun Wong, Weilin Li, Johnny S. H. Kwan, Rui Yang, Aden K. Y. Chan, Yujuan Dong, Feng Wu, Bin Zhang, Alvin H. K. Cheung, William K. K. Wu, Alfred S. L. Cheng, Jun Yu, Nathalie Wong, Wei Kang, Ka Fai To
Oncogene. 2018; 37(9): 1159–1174. Published online 2017 Dec 13. doi: 10.1038/s41388-017-0029-7
PMCID:
PMC5861093
AbstractArticlePDF–6.1M
10.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M
11.
The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer
Madhumitha Rengasamy, Fan Zhang, Ajay Vashisht, Won-Min Song, Francesca Aguilo, Yifei Sun, SiDe Li, Weijia Zhang, Bin Zhang, James A. Wohlschlegel, Martin J. Walsh
Nucleic Acids Res. 2017 Nov 2; 45(19): 11106–11120. Published online 2017 Aug 21. doi: 10.1093/nar/gkx727
PMCID:
PMC5737218
AbstractArticlePDF–4.1M
12.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
13.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
14.
srGAP1 mediates the migration inhibition effect of Slit2-Robo1 in colorectal cancer
Yuyang Feng, Lei Feng, Di Yu, Jian Zou, Zhaohui Huang
J Exp Clin Cancer Res. 2016; 35: 191. Published online 2016 Dec 7. doi: 10.1186/s13046-016-0469-x
PMCID:
PMC5142155
AbstractArticlePDF–2.5M
15.
Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 Confer Risk for Congenital Anomalies of the Kidney and Urinary Tract
Daw-Yang Hwang, Stefan Kohl, Xueping Fan, Asaf Vivante, Stefanie Chan, Gabriel C Dworschak, Julian Schulz, Albertien M van Eerde, Alina C Hilger, Heon Yung Gee, Tracie Pennimpede, Bernhard G Herrmann, Glenn van de Hoek, Kirsten Y Renkema, Christoph Schell, Tobias B Huber, Heiko M Reutter, Neveen A Soliman, Natasa Stajic, Radovan Bogdanovic, Elijah O Kehinde, Richard P Lifton, Velibor Tasic, Weining Lu, Friedhelm Hildebrandt
Hum Genet. Author manuscript; available in PMC 2016 Aug 1.
Published in final edited form as: Hum Genet. 2015 Aug; 134(8): 905–916. Published online 2015 May 31. doi: 10.1007/s00439-015-1570-5
PMCID:
PMC4497857
AbstractArticlePDF–2.5M
16.
An extracellular matrix-specific GEF-GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration
Matthew L. Kutys, Kenneth M. Yamada
Nat Cell Biol. Author manuscript; available in PMC 2015 Mar 1.
Published in final edited form as: Nat Cell Biol. 2014 Sep; 16(9): 909–917. Published online 2014 Aug 24. doi: 10.1038/ncb3026
PMCID:
PMC4150836
ArticlePDF–2.6M
17.
srGAP1 regulates lamellipodial dynamics and cell migratory behavior by modulating Rac1 activity
Daisuke Yamazaki, Toshiki Itoh, Hiroaki Miki, Tadaomi Takenawa
Mol Biol Cell. 2013 Nov 1; 24(21): 3393–3405. doi: 10.1091/mbc.E13-04-0178
PMCID:
PMC3814155
AbstractArticlePDF–2.2M
18.
SRGAP1 Is a Candidate Gene for Papillary Thyroid Carcinoma Susceptibility
Huiling He, Agnieszka Bronisz, Sandya Liyanarachchi, Rebecca Nagy, Wei Li, Yungui Huang, Keiko Akagi, Motoyasu Saji, Dorota Kula, Anna Wojcicka, Nikhil Sebastian, Bernard Wen, Zbigniew Puch, Michal Kalemba, Elzbieta Stachlewska, Malgorzata Czetwertynska, Joanna Dlugosinska, Kinga Dymecka, Rafal Ploski, Marek Krawczyk, Patrick J. Morrison, Matthew D. Ringel, Richard T. Kloos, Krystian Jazdzewski, David E. Symer, Veronica J. Vieland, Michael Ostrowski, Barbara Jarząb, Albert de la Chapelle
J Clin Endocrinol Metab. 2013 May; 98(5): E973–E980. Published online 2013 Mar 28. doi: 10.1210/jc.2012-3823
PMCID:
PMC3644596
AbstractArticle
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
The Corticofugal Neuron-Associated Genes ROBO1, SRGAP1, and CTIP2 Exhibit an Anterior to Posterior Gradient of Expression in Early Fetal Human Neocortex Development
Bui Kar Ip, Nadhim Bayatti, Nicholas J. Howard, Susan Lindsay, Gavin J. Clowry
Cereb Cortex. 2011 Jun; 21(6): 1395–1407. Published online 2010 Nov 8. doi: 10.1093/cercor/bhq219
PMCID:
PMC3097990
AbstractArticlePDF–1.4M

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