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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108867742.

Differential Role of the RAC1-Binding Proteins FAM49b (CYRI-B) and CYFIP1 in Platelets

Dmitri Sisario, Markus Spindler, Katharina J. Ermer, Noah Grütz, Leo Nicolai, Florian Gaertner, Laura M. Machesky, Markus Bender

Cells. 2024 Feb; 13(4): 299. Published online 2024 Feb 6. doi: 10.3390/cells13040299

PMCID:: PMC10886774

Abstract Article PDF–5.7M

Select item 103992323.

Overexpression of the autism candidate gene Cyfip1 pathologically enhances olivo-cerebellar signaling in mice

Silas E. Busch, Dana H. Simmons, Eric Gama, Xiaofei Du, Francesco Longo, Christopher M. Gomez, Eric Klann, Christian Hansel

Front Cell Neurosci. 2023; 17: 1219270. Published online 2023 Jul 20. doi: 10.3389/fncel.2023.1219270

PMCID:: PMC10399232

Abstract Article PDF–3.4M

Select item 94819334.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 88634195.

Deficiency of the neurodevelopmental disorder-associated gene Cyfip2 alters the retinal ganglion cell properties and visual acuity

Taro Chaya, Hiroshi Ishikane, Leah R Varner, Yuko Sugita, Yamato Maeda, Ryotaro Tsutsumi, Daisuke Motooka, Daisuke Okuzaki, Takahisa Furukawa

Hum Mol Genet. 2022 Feb 15; 31(4): 535–547. Published online 2021 Sep 11. doi: 10.1093/hmg/ddab268

PMCID:: PMC8863419

Abstract Article PDF–1.8M

Select item 85687346.

CYFIP1 dosages exhibit divergent behavioral impact via diametric regulation of NMDAR complex translation in mouse models of psychiatric disorders

Nam-Shik Kim, Francisca Rojas Ringeling, Ying Zhou, Ha Nam Nguyen, Stephanie J. Temme, Yu-Ting Lin, Stephen Eacker, Valina L. Dawson, Ted M. Dawson, Bo Xiao, Kuei-sen Hsu, Stefan Canzar, Weidong Li, Paul Worley, Kimberly M. Christian, Ki-Jun Yoon, Hongjun Song, Guo-li Ming

Biol Psychiatry. Author manuscript; available in PMC 2023 Nov 15.

Published in final edited form as: Biol Psychiatry. 2022 Nov 15; 92(10): 815–826. Published online 2021 May 5. doi: 10.1016/j.biopsych.2021.04.023

PMCID:: PMC8568734

Abstract Article PDF–2.6M

Select item 81444037.

Haploinsufficiency of the schizophrenia and autism risk gene Cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and Arp2/3 mediated actin dependent mechanisms

Niels Haan, Laura J. Westacott, Jenny Carter, Michael J. Owen, William P. Gray, Jeremy Hall, Lawrence S. Wilkinson

Transl Psychiatry. 2021; 11: 313. Published online 2021 May 24. doi: 10.1038/s41398-021-01415-6

PMCID:: PMC8144403

Abstract Article PDF–3.0M

Select item 79387708.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 76665829.

Vascular surveillance by haptotactic blood platelets in inflammation and infection

Leo Nicolai, Karin Schiefelbein, Silvia Lipsky, Alexander Leunig, Marie Hoffknecht, Kami Pekayvaz, Ben Raude, Charlotte Marx, Andreas Ehrlich, Joachim Pircher, Zhe Zhang, Inas Saleh, Anna-Kristina Marel, Achim Löf, Tobias Petzold, Michael Lorenz, Konstantin Stark, Robert Pick, Gerhild Rosenberger, Ludwig Weckbach, Bernd Uhl, Sheng Xia, Christoph Andreas Reichel, Barbara Walzog, Christian Schulz, Vanessa Zheden, Markus Bender, Rong Li, Steffen Massberg, Florian Gaertner

Nat Commun. 2020; 11: 5778. Published online 2020 Nov 13. doi: 10.1038/s41467-020-19515-0

Correction in:: Nat Commun. 2022; 13: 4645.

PMCID:: PMC7666582

Abstract Article PDF–6.8M

Select item 741853410.

Complex Interactions between Genes and Social Environment Cause Phenotypes Associated with Autism Spectrum Disorders in Mice

Monika Sledziowska, Shireene Kalbassi, Stéphane J. Baudouin

eNeuro. 2020 Jul-Aug; 7(4): ENEURO.0124-20.2020. Prepublished online 2020 Jul 15. Published online 2020 Aug 5. doi: 10.1523/ENEURO.0124-20.2020

PMCID:: PMC7418534

Abstract Article PDF–2.3M

Select item 741599111.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 705513412.

Persistent Cyfip1 Expression Is Required to Maintain the Adult Subventricular Zone Neurogenic Niche

Christa Whelan Habela, Ki-Jun Yoon, Nam-Shik Kim, Arens Taga, Kassidy Bell, Dwight E. Bergles, Nicholas J. Maragakis, Guo-li Ming, Hongjun Song

J Neurosci. 2020 Mar 4; 40(10): 2015–2024. doi: 10.1523/JNEUROSCI.2249-19.2020

PMCID:: PMC7055134

Abstract Article PDF–3.5M

Select item 691362413.

Differential cell-type-expression of CYFIP1 and CYFIP2 in the adult mouse hippocampus

Yinhua Zhang, Hyae Rim Kang, Kihoon Han

Anim Cells Syst (Seoul) 2019; 23(6): 380–383. Published online 2019 Nov 24. doi: 10.1080/19768354.2019.1696406

PMCID:: PMC6913624

Abstract Article PDF–1.0M

Select item 672312214.

Cyfip1 Haploinsufficiency Increases Compulsive-Like Behavior and Modulates Palatable Food Intake in Mice: Dependence on Cyfip2 Genetic Background, Parent-of Origin, and Sex

Richard K. Babbs, Jacob A. Beierle, Qiu T. Ruan, Julia C. Kelliher, Melanie M. Chen, Ashley X. Feng, Stacey L. Kirkpatrick, Fabiola A. Benitez, Fred A. Rodriguez, Johanne J. Pierre, Jeya Anandakumar, Vivek Kumar, Megan K. Mulligan, Camron D. Bryant

G3 (Bethesda) 2019 Sep; 9(9): 3009–3022. Published online 2019 Jul 19. doi: 10.1534/g3.119.400470

PMCID:: PMC6723122

Abstract Article PDF–1.8M

Select item 667200115.

The autism- and schizophrenia-associated protein CYFIP1 regulates bilateral brain connectivity and behaviour

Nuria Domínguez-Iturza, Adrian C. Lo, Disha Shah, Marcelo Armendáriz, Anna Vannelli, Valentina Mercaldo, Massimo Trusel, Ka Wan Li, Denise Gastaldo, Ana Rita Santos, Zsuzsanna Callaerts-Vegh, Rudi D’Hooge, Manuel Mameli, Annemie Van der Linden, August B. Smit, Tilmann Achsel, Claudia Bagni

Nat Commun. 2019; 10: 3454. Published online 2019 Aug 1. doi: 10.1038/s41467-019-11203-y

PMCID:: PMC6672001

Abstract Article PDF–3.8M

Select item 663581016.

Cyfip1 Haploinsufficiency Does Not Alter GABA_A Receptor δ-Subunit Expression and Tonic Inhibition in Dentate Gyrus PV⁺ Interneurons and Granule Cells

Simon Trent, Jeremy Hall, William M. Connelly, Adam C. Errington

eNeuro. 2019 May-Jun; 6(3): ENEURO.0364-18.2019. Prepublished online 2019 Jun 17. Published online 2019 Jun 28. doi: 10.1523/ENEURO.0364-18.2019

PMCID:: PMC6635810

Abstract Article PDF–3.8M

Select item 645951017.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 638178518.

Autism and Schizophrenia-Associated CYFIP1 Regulates the Balance of Synaptic Excitation and Inhibition

Elizabeth C. Davenport, Blanka R. Szulc, James Drew, James Taylor, Toby Morgan, Nathalie F. Higgs, Guillermo López-Doménech, Josef T. Kittler

Cell Rep. 2019 Feb 19; 26(8): 2037–2051.e6. Published online 2019 Feb 19. doi: 10.1016/j.celrep.2019.01.092

PMCID:: PMC6381785

Abstract Article

Select item 634110319.

Behavioral training rescues motor deficits in Cyfip1 haploinsufficiency mouse model of autism spectrum disorders

Sven O. Bachmann, Monika Sledziowska, Ellen Cross, Shireene Kalbassi, Sophie Waldron, Fangli Chen, Adam Ranson, Stéphane J. Baudouin

Transl Psychiatry. 2019; 9: 29. Published online 2019 Jan 21. doi: 10.1038/s41398-018-0338-9

PMCID:: PMC6341103

Abstract Article PDF–1.8M

Select item 633802420.

Smaller Body Size, Early Postnatal Lethality, and Cortical Extracellular Matrix-Related Gene Expression Changes of Cyfip2-Null Embryonic Mice

Yinhua Zhang, Hyojin Kang, Yeunkum Lee, Yoonhee Kim, Bokyoung Lee, Jin Yong Kim, Chunmei Jin, Shinhyun Kim, Hyun Kim, Kihoon Han

Front Mol Neurosci. 2018; 11: 482. Published online 2019 Jan 4. doi: 10.3389/fnmol.2018.00482

PMCID:: PMC6338024

Abstract Article PDF–2.8M

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