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Items: 1 to 20 of 41

1.
The Role of SLIT3–ROBO4 Signaling in Endoplasmic Reticulum Stress–Induced Delayed Corneal Epithelial and Nerve Regeneration
Rong Chen, Yao Wang, Zhenzhen Zhang, Xiaolei Wang, Ya Li, Min Wang, Huifeng Wang, Muchen Dong, Qingjun Zhou, Lingling Yang
Invest Ophthalmol Vis Sci. 2024 May; 65(5): 8. Published online 2024 May 3. doi: 10.1167/iovs.65.5.8
PMCID:
PMC11077912
AbstractArticlePDF–8.7M
2.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
3.
The role of TET2-mediated ROBO4 hypomethylation in the development of diabetic retinopathy
Liangliang Zhao, Haitao Xu, Xin Liu, Yan Cheng, Jia’nan Xie
J Transl Med. 2023; 21: 455. Published online 2023 Jul 10. doi: 10.1186/s12967-023-04310-4
PMCID:
PMC10332081
AbstractArticlePDF–6.8M
4.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
5.
Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1
Xiahui Li, Shujing Li, Bowen Li, Yanan Li, Sattout Aman, Kangkai Xia, Yuxi Yang, Bashir Ahmad, Huijian Wu
NPJ Precis Oncol. 2021; 5: 20. Published online 2021 Mar 19. doi: 10.1038/s41698-021-00158-3
PMCID:
PMC7979705
AbstractArticlePDF–6.8M
6.
miR-140-5p regulates vascular smooth muscle cell viability, migration and apoptosis by targeting ROBO4 gene expression in atherosclerosis
Yi Luo, Yangmin Li, Hong Peng, Yu Zhao
Mol Med Rep. 2021 Mar; 23(3): 213. Published online 2021 Jan 19. doi: 10.3892/mmr.2021.11852
PMCID:
PMC7845623
AbstractArticlePDF–6.7M
7.
Structural insights and evaluation of the potential impact of missense variants on the interactions of SLIT2 with ROBO1/4 in cancer progression
Debmalya Sengupta, Gairika Bhattacharya, Sayak Ganguli, Mainak Sengupta
Sci Rep. 2020; 10: 21909. Published online 2020 Dec 14. doi: 10.1038/s41598-020-78882-2
PMCID:
PMC7736846
AbstractArticlePDF–9.2M
8.
Rare deleterious variants of NOTCH1, GATA4, SMAD6, and ROBO4 are enriched in BAV with early onset complications but not in BAV with heritable thoracic aortic disease
Fadi I. Musfee, Dongchuan Guo, Amélie C. Pinard, Ellen M. Hostetler, Elizabeth E. Blue, Deborah A. Nickerson, University of Washington Center for Mendelian Genomics (UW‐CMG), Michael J. Bamshad, Dianna M. Milewicz, Siddharth K. Prakash
Mol Genet Genomic Med. 2020 Oct; 8(10): e1406. Published online 2020 Aug 3. doi: 10.1002/mgg3.1406
PMCID:
PMC7549564
AbstractArticlePDF–250K
9.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
10.
Annexin A2 is a Robo4 ligand that modulates ARF6 activation-associated cerebral trans-endothelial permeability
Wenlu Li, Zhigang Chen, Jing Yuan, Zhanyang Yu, Chongjie Cheng, Qiuchen Zhao, Lena Huang, Katherine A Hajjar, Zhong Chen, Eng H Lo, Haibin Dai, Xiaoying Wang
J Cereb Blood Flow Metab. 2019 Oct; 39(10): 2048–2060. Published online 2018 May 22. doi: 10.1177/0271678X18777916
PMCID:
PMC6775579
AbstractArticlePDF–2.0M
11.
Regulatory mechanisms of Robo4 and their effects on angiogenesis
Chang Dai, Qiaoyun Gong, Yan Cheng, Guanfang Su
Biosci Rep. 2019 Jul 31; 39(7): BSR20190513. Prepublished online 2019 Jun 3. Published online 2019 Jul 10. doi: 10.1042/BSR20190513
PMCID:
PMC6620384
AbstractArticlePDF–1.2M
12.
Upregulated VEGF and Robo4 correlate with the reduction of miR-15a in the development of diabetic retinopathy
Qiaoyun Gong, Fuqiang Li, Jia’nan Xie, Guanfang Su
Endocrine. 2019; 65(1): 35–45. Published online 2019 Apr 12. doi: 10.1007/s12020-019-01921-0
PMCID:
PMC6606763
AbstractArticlePDF–1.5M
13.
TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile
Karen Dendoncker, Steven Timmermans, Jolien Vandewalle, Melanie Eggermont, Joanna Lempiäinen, Evelien Van Hamme, Sylviane Dewaele, Sofie Vandevyver, Marlies Ballegeer, Jolien Souffriau, Lise Van Wyngene, Kelly Van Looveren, Tineke Vanderhaeghen, Rudi Beyaert, Karolien De Bosscher, Jorma J. Palvimo, Marc Van Montagu, Claude Libert
Proc Natl Acad Sci U S A. 2019 Jun 25; 116(26): 12942–12951. Published online 2019 Jun 10. doi: 10.1073/pnas.1821565116
Correction in:
Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15745.
PMCID:
PMC6600915
AbstractArticlePDF–1.7M
14.
Robo 4 - the double-edged sword in prostate cancer: impact on cancer cell aggressiveness and tumor vasculature
Andreas Pircher, Georg Schäfer, Andrea Eigentler, Renate Pichler, Martin Puhr, Eberhard Steiner, Wolfgang Horninger, Eberhard Gunsilius, Helmut Klocker, Isabel Heidegger
Int J Med Sci. 2019; 16(1): 115–124. Published online 2019 Jan 1. doi: 10.7150/ijms.28735
PMCID:
PMC6332478
AbstractArticlePDF–1.1M
15.
ROBO4 Variants Predispose Individuals to Bicuspid Aortic Valve and Thoracic Aortic Aneurysm
Russell A Gould, Hamza Aziz, Courtney E Woods, Manuel Alejandro Seman-Senderos, Elizabeth Sparks, Christoph Preuss, Florian Wünnemann, Djahida Bedja, Cassandra R Moats, Sarah A McClymont, Rebecca Rose, Nara Sobeira, Hua Ling, Gretchen MacCarrick, Ajay Anand Kumar, Ilse Luyckx, Elyssa Cannaerts, Aline Verstraeten, Hanna M Björk, Ann-Cathrin Lehsau, Vinod Jaskula-Ranga, Henrik Lauridsen, Asad A Shah, Christopher L Bennett, Patrick T Ellinor, Honghuang Lin, Eric M Isselbacher, Christian Lacks Lino Cardenas, Jonathan T Butcher, G. Chad Hughes, Mark E. Lindsay, Center for Mendelian Genomics, MIBAVA Leducq Consortium, Luc Mertens, Anders Franco-Cereceda, Judith MA Verhagen, Marja Wessels, Salah A Mohamed, Eriksson Per, Seema Mital, Lut Van Laer, Bart L Loeys, Gregor Andelfinger, Andrew S McCallion, Harry C Dietz
Nat Genet. Author manuscript; available in PMC 2019 May 19.
Published in final edited form as: Nat Genet. 2019 Jan; 51(1): 42–50. Published online 2018 Nov 19. doi: 10.1038/s41588-018-0265-y
PMCID:
PMC6309588
AbstractArticlePDF–2.0M
16.
A Global Analysis of The Receptor Tyrosine Kinase – Protein Phosphatase Interactome
Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar
Mol Cell. Author manuscript; available in PMC 2017 Oct 31.
Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 347–360. Published online 2017 Jan 5. doi: 10.1016/j.molcel.2016.12.004
PMCID:
PMC5663465
AbstractArticlePDF–2.1M
17.
Endothelial Cell–Specific Expression of Roundabout 4 Is Regulated by Differential DNA Methylation of the Proximal Promoter
Yoshiaki Okada, Nobuaki Funahashi, Toru Tanaka, Yuji Nishiyama, Lei Yuan, Keisuke Shirakura, Alexis S. Turjman, Yoshihiro Kano, Hiroki Naruse, Ayano Suzuki, Miki Sakai, Jiang Zhixia, Kenji Kitajima, Kenji Ishimoto, Nobumasa Hino, Masuo Kondoh, Yohei Mukai, Shinsaku Nakagawa, Guillermo García-Cardeña, William C. Aird, Takefumi Doi
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Apr 3.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2014 Jul; 34(7): 1531–1538. Published online 2014 May 22. doi: 10.1161/ATVBAHA.114.303818
PMCID:
PMC5378492
AbstractArticlePDF–1.3M
18.
Biomarkers of evasive resistance predict disease progression in cancer patients treated with antiangiogenic therapies
Andreas Pircher, Karin Jöhrer, Florian Kocher, Normann Steiner, Ivo Graziadei, Isabel Heidegger, Renate Pichler, Nicolai Leonhartsberger, Christian Kremser, Johann Kern, Gerold Untergasser, Eberhard Gunsilius, Wolfgang Hilbe
Oncotarget. 2016 Apr 12; 7(15): 20109–20123. Published online 2016 Mar 4. doi: 10.18632/oncotarget.7915
PMCID:
PMC4991441
AbstractArticlePDF–4.8M
19.
Clinical and Prognostic Implications of Roundabout 4 (Robo4) in Adult Patients with Acute Myeloid Leukemia
Yin-Kai Chen, Hsin-An Hou, Jih-Luh Tang, Jie-Yang Jhuang, Yan-Jun Lai, Ming-Cheng Lee, Yuan-Yeh Kuo, Wen-Chien Chou, Chieh-Yu Liu, Chung-Wu Lin, Shih-Sung Chuang, Chien-Yuan Chen, Mei-Hsuan Tseng, Chi-Fei Huang, Ying-Chieh Chiang, Fen-Yu Lee, Ming-Chih Liu, Chia-Wen Liu, Ming Yao, Shang-Yi Huang, Bor-Sheng Ko, Szu-Chun Hsu, Shang-Ju Wu, Woei Tsay, Yao-Chang Chen, Hwei-Fang Tien
PLoS One. 2015; 10(3): e0119831. Published online 2015 Mar 20. doi: 10.1371/journal.pone.0119831
PMCID:
PMC4368775
AbstractArticlePDF–366K
20.
Raised Plasma Robo4 and Cardiac Surgery-Associated Acute Kidney Injury
Anne Burke-Gaffney, Tatiana Svermova, Sharon Mumby, Simon J. Finney, Timothy W. Evans
PLoS One. 2014; 9(10): e111459. Published online 2014 Oct 31. doi: 10.1371/journal.pone.0111459
PMCID:
PMC4216014
AbstractArticlePDF–542K

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