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Items: 1 to 20 of 58

1.
Phosphorylated CPI-17 and MLC2 as Biomarkers of Coronary Artery Spasm–Induced Sudden Cardiac Death
Yiming Dong, Jianfeng Wang, Chenteng Yang, Junxia Bao, Xia Liu, Hao Chen, Xiaojing Zhang, Weibo Shi, Lihua Zhang, Qian Qi, Yingmin Li, Songjun Wang, Rufei Ma, Bin Cong, Guozhong Zhang
Int J Mol Sci. 2024 Mar; 25(5): 2941. Published online 2024 Mar 3. doi: 10.3390/ijms25052941
PMCID:
PMC10932290
AbstractArticlePDF–23M
2.
A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins
Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux
Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611
PMCID:
PMC8951556
AbstractArticlePDF–4.4M
3.
Molecular basis of force-pCa relation in MYL2 cardiomyopathy mice: Role of the super-relaxed state of myosin
Chen-Ching Yuan, Katarzyna Kazmierczak, Jingsheng Liang, Weikang Ma, Thomas C. Irving, Danuta Szczesna-Cordary
Proc Natl Acad Sci U S A. 2022 Feb 22; 119(8): e2110328119. Published online 2022 Feb 17. doi: 10.1073/pnas.2110328119
PMCID:
PMC8872785
AbstractArticlePDF–1.3M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Novel circular RNA circSOBP governs amoeboid migration through the regulation of the miR‐141‐3p/MYPT1/p‐MLC2 axis in prostate cancer
Fan Chao, Zhenyu Song, Shiyu Wang, Zhe Ma, Zhiyuan Zhuo, Ting Meng, Guoxiong Xu, Gang Chen
Clin Transl Med. 2021 Mar; 11(3): e360. Published online 2021 Mar 26. doi: 10.1002/ctm2.360
PMCID:
PMC8002909
AbstractArticlePDF–8.2M
6.
Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis
Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D. Malihi, Mincheol Park, Ruth M. Alvarez, Li Peng Yap, Parag Mallick, Jonathan E. Katz, Mitchell E. Gross, Kian Kani
Oncogene. Author manuscript; available in PMC 2020 Sep 29.
Published in final edited form as: Oncogene. 2019 Apr; 38(16): 3003–3018. Published online 2018 Dec 21. doi: 10.1038/s41388-018-0638-9
PMCID:
PMC7523706
AbstractArticlePDF–2.3M
7.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
8.
Upregulation of RIN3 induces endosomal dysfunction in Alzheimer’s disease
Ruinan Shen, Xiaobei Zhao, Lu He, Yongbo Ding, Wei Xu, Suzhen Lin, Savannah Fang, Wanlin Yang, Kijung Sung, Brian Spencer, Robert A. Rissman, Ming Lei, Jianqing Ding, Chengbiao Wu
Transl Neurodegener. 2020; 9: 26. Published online 2020 Jun 18. doi: 10.1186/s40035-020-00206-1
PMCID:
PMC7301499
AbstractArticlePDF–14M
9.
Novel frameshift variant in MYL2 reveals molecular differences between dominant and recessive forms of hypertrophic cardiomyopathy
Sathiya N. Manivannan, Sihem Darouich, Aida Masmoudi, David Gordon, Gloria Zender, Zhe Han, Sara Fitzgerald-Butt, Peter White, Kim L. McBride, Maher Kharrat, Vidu Garg
PLoS Genet. 2020 May; 16(5): e1008639. Published online 2020 May 26. doi: 10.1371/journal.pgen.1008639
PMCID:
PMC7274480
AbstractArticlePDF–2.9M
10.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
11.
Cardiac MLC2 kinase is localized to the Z-disc and interacts with α-actinin2
Lawrence X. Cai, Yohei Tanada, Gregory D. Bello, James C. Fleming, Fariz F. Alkassis, Thomas Ladd, Todd Golde, Jin Koh, Sixue Chen, Hideko Kasahara
Sci Rep. 2019; 9: 12580. Published online 2019 Aug 29. doi: 10.1038/s41598-019-48884-w
PMCID:
PMC6715661
AbstractArticlePDF–5.4M
12.
Slow Cardiac Myosin Regulatory Light Chain 2 (MYL2) was Down‐Expressed in Chronic Heart Failure Patients
Yuanhong Li, Gang Wu, Qizhu Tang, MD Qizhu Tang, Congxin Huang, Hong Jiang, Lisong Shi, Xin Tu, Jinqi Huang, Xiaoqing Zhu, Hongli Wang
Clin Cardiol. 2011 Jan; 34(1): 30–34. Published online 2010 Dec 10. doi: 10.1002/clc.20832
PMCID:
PMC6652384
AbstractArticlePDF–2.8M
13.
Myosin regulatory light chain mutation found in hypertrophic cardiomyopathy patients increases isometric force production in transgenic mice
Katarzyna Kazmierczak, Priya Muthu, Wenrui Huang, Michelle Jones, Yingcai Wang, Danuta Szczesna-Cordary
Biochem J. Author manuscript; available in PMC 2019 Jun 23.
Published in final edited form as: Biochem J. 2012 Feb 15; 442(1): 95–103. doi: 10.1042/BJ20111145
PMCID:
PMC6589164
AbstractArticlePDF–1016K
14.
Slow-twitch skeletal muscle defects accompany cardiac dysfunction in transgenic mice with a mutation in the myosin regulatory light chain
Katarzyna Kazmierczak, Jingsheng Liang, Chen-Ching Yuan, Sunil Yadav, Yoel H. Sitbon, Katherina Walz, Weikang Ma, Thomas C. Irving, Jenice X. Cheah, Aldrin V. Gomes, Danuta Szczesna-Cordary
FASEB J. 2019 Mar; 33(3): 3152–3166. Published online 2018 Oct 26. doi: 10.1096/fj.201801402R
PMCID:
PMC6404564
AbstractArticle
15.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
16.
Hypertrophic cardiomyopathy mutation R58Q in the myosin regulatory light chain perturbs thick filament-based regulation in cardiac muscle
Thomas Kampourakis, Saraswathi Ponnam, Malcolm Irving
J Mol Cell Cardiol. 2018 Apr; 117: 72–81. doi: 10.1016/j.yjmcc.2018.02.009
PMCID:
PMC5883317
AbstractArticlePDF–962K
17.
Sarcomeric perturbations of myosin motors lead to dilated cardiomyopathy in genetically modified MYL2 mice
Chen-Ching Yuan, Katarzyna Kazmierczak, Jingsheng Liang, Zhiqun Zhou, Sunil Yadav, Aldrin V. Gomes, Thomas C. Irving, Danuta Szczesna-Cordary
Proc Natl Acad Sci U S A. 2018 Mar 6; 115(10): E2338–E2347. Published online 2018 Feb 20. doi: 10.1073/pnas.1716925115
PMCID:
PMC5877945
AbstractArticlePDF–1.5M
18.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
19.
A Cardiomyopathy Mutation in the Myosin Essential Light Chain Alters Actomyosin Structure
Piyali Guhathakurta, Ewa Prochniewicz, Osha Roopnarine, John A. Rohde, David D. Thomas
Biophys J. 2017 Jul 11; 113(1): 91–100. Published online 2017 Jul 11. doi: 10.1016/j.bpj.2017.05.027
PMCID:
PMC5510710
AbstractArticlePDF–1.1M
20.
Cardiac Contractility, Motor Function and Cross-Bridge Kinetics in N47K-RLC Mutant Mice
Li Wang, Katarzyna Kazmierczak, Chen-Ching Yuan, Sunil Yadav, Masataka Kawai, Danuta Szczesna-Cordary
FEBS J. Author manuscript; available in PMC 2018 Jun 1.
Published in final edited form as: FEBS J. 2017 Jun; 284(12): 1897–1913. Published online 2017 May 25. doi: 10.1111/febs.14096
PMCID:
PMC5490660
AbstractArticlePDF–858K

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