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Select item 108507811.

Paxillin family proteins Hic-5 and LPXN promote lipid storage by regulating the ubiquitination degradation of CIDEC

Mingyu Fang, Xu Liu, Wenbo Xu, Xing Wang, Lin Xu, Tong-jin Zhao, Peng Li, Hui Yang

J Biol Chem. 2024 Feb; 300(2): 105610. Published online 2023 Dec 28. doi: 10.1016/j.jbc.2023.105610

PMCID:: PMC10850781

Abstract Article PDF–2.7M

Select item 105658762.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 103338843.

Large‐scale phosphomimetic screening identifies phospho‐modulated motif‐based protein interactions

Johanna Kliche, Dimitriya Hristoforova Garvanska, Leandro Simonetti, Dilip Badgujar, Doreen Dobritzsch, Jakob Nilsson, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2023 Jul; 19(7): e11164. Published online 2023 May 23. doi: 10.15252/msb.202211164

PMCID:: PMC10333884

Abstract Article PDF–5.0M

Select item 102374224.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 91052355.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 87690726.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

Select item 78737017.

Global proteomics of Ubqln2-based murine models of ALS

Alexandra M. Whiteley, Miguel A. Prado, Stefanie A.H. de Poot, Joao A. Paulo, Marissa Ashton, Sara Dominguez, Martin Weber, Hai Ngu, John Szpyt, Mark P. Jedrychowski, Amy Easton, Steven P. Gygi, Thimo Kurz, Mervyn J. Monteiro, Eric J. Brown, Daniel Finley

J Biol Chem. 2021 Jan-Jun; 296: 100153. Published online 2020 Dec 10. doi: 10.1074/jbc.RA120.015960

PMCID:: PMC7873701

Abstract Article PDF–3.0M

Select item 77624608.

Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway

Liansheng Sha, Deying Ma, Cuili Chen

Aging (Albany NY) 2020 Dec 15; 12(23): 23598–23608. Published online 2020 Dec 13. doi: 10.18632/aging.103546

PMCID:: PMC7762460

Abstract Article PDF–1.7M

Select item 77370989.

Paxillin family of focal adhesion adaptor proteins and regulation of cancer cell invasion

Kyle M. Alpha, Weiyi Xu, Christopher E. Turner

Int Rev Cell Mol Biol. Author manuscript; available in PMC 2021 Aug 6.

Published in final edited form as: Int Rev Cell Mol Biol. 2020; 355: 1–52. Published online 2020 Aug 6. doi: 10.1016/bs.ircmb.2020.05.003

PMCID:: PMC7737098

Abstract Article PDF–1.9M

Select item 742732710.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 737961711.

A mitochondrial ROS pathway controls matrix metalloproteinase 9 levels and invasive properties in RAS‐activated cancer cells

Kazunori Mori, Tetsu Uchida, Toshihiko Yoshie, Yuko Mizote, Fumihiro Ishikawa, Masato Katsuyama, Motoko Shibanuma

FEBS J. 2019 Feb; 286(3): 459–478. Published online 2018 Oct 13. doi: 10.1111/febs.14671

PMCID:: PMC7379617

Abstract Article PDF–1.2M

Select item 688088012.

The focal adhesion scaffold protein Hic-5 regulates vimentin organization in fibroblasts

Rishel B. Vohnoutka, Anushree C. Gulvady, Gregory Goreczny, Kyle Alpha, Samuel K. Handelman, Jonathan Z. Sexton, Christopher E. Turner

Mol Biol Cell. 2019 Dec 1; 30(25): 3037–3056. doi: 10.1091/mbc.E19-08-0442

PMCID:: PMC6880880

Abstract Article PDF–7.8M

Select item 686124813.

HIC-5 in cancer-associated fibroblasts contributes to esophageal squamous cell carcinoma progression

Xuanling Du, Qiping Xu, Duyi Pan, Dongke Xu, Baolin Niu, Wenting Hong, Rui Zhang, Xiaobo Li, Shiyao Chen

Cell Death Dis. 2019 Dec; 10(12): 873. Published online 2019 Nov 18. doi: 10.1038/s41419-019-2114-z

PMCID:: PMC6861248

Abstract Article PDF–3.4M

Select item 685063414.

Regulation of mitochondrial ROS production by HIC‐5: a common feature of oncogene‐induced senescence and tumor invasiveness?

Wolfgang Doppler, Pidder Jansen‐Dürr

FEBS J. 2019 Feb; 286(3): 456–458. Published online 2019 Jan 25. doi: 10.1111/febs.14746

PMCID:: PMC6850634

Abstract Article PDF–161K

Select item 676993015.

Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners

Eunate Gallardo-Vara, Lidia Ruiz-Llorente, Juan Casado-Vela, María J. Ruiz-Rodríguez, Natalia López-Andrés, Asit K. Pattnaik, Miguel Quintanilla, Carmelo Bernabeu

Cells. 2019 Sep; 8(9): 1082. Published online 2019 Sep 13. doi: 10.3390/cells8091082

PMCID:: PMC6769930

Abstract Article PDF–4.3M

Select item 675788816.

The Multiple LIM Domain-Containing Adaptor Protein Hic-5 Synaptically Colocalizes and Interacts with the Dopamine Transporter

Ana M. Carneiro, Susan L. Ingram, Jean-Martin Beaulieu, Ava Sweeney, Susan G. Amara, Sheila M. Thomas, Marc G. Caron, Gonzalo E. Torres

J Neurosci. 2002 Aug 15; 22(16): 7045–7054. doi: 10.1523/JNEUROSCI.22-16-07045.2002

PMCID:: PMC6757888

Abstract Article PDF–1.1M

Select item 608070617.

Hic-5 expression is a major indicator of cancer cell morphology, migration, and plasticity in three-dimensional matrices

Anushree C. Gulvady, Fatemeh Dubois, Nicholas O. Deakin, Gregory J. Goreczny, Christopher E. Turner

Mol Biol Cell. 2018 Jul 15; 29(14): 1704–1717. doi: 10.1091/mbc.E18-02-0092

PMCID:: PMC6080706

Abstract Article PDF–3.0M

Select item 594018718.

Different chromatin and DNA sequence characteristics define glucocorticoid receptor binding sites that are blocked or not blocked by coregulator Hic-5

Brian H. Lee, Michael R. Stallcup

PLoS One. 2018; 13(5): e0196965. Published online 2018 May 8. doi: 10.1371/journal.pone.0196965

PMCID:: PMC5940187

Abstract Article PDF–6.2M

Select item 587608319.

Hic-5 Regulates Fibrillar Adhesion Formation to Control Tumor Extracellular Matrix Remodeling through Interaction with Tensin1

Gregory J. Goreczny, Ian J. Forsythe, Christopher E. Turner

Oncogene. Author manuscript; available in PMC 2018 Jul 19.

Published in final edited form as: Oncogene. 2018 Mar; 37(13): 1699–1713. Published online 2018 Jan 19. doi: 10.1038/s41388-017-0074-2

PMCID:: PMC5876083

Abstract Article PDF–3.8M

Select item 563060020.

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism

Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell

Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8