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Items: 1 to 20 of 43

1.
GABBR2 as a Downstream Effector of the Androgen Receptor Induces Cisplatin Resistance in Bladder Cancer
Mohammad Amin Elahi Najafi, Masato Yasui, Yuki Teramoto, Tomoyuki Tatenuma, Guiyang Jiang, Hiroshi Miyamoto
Int J Mol Sci. 2023 Sep; 24(18): 13733. Published online 2023 Sep 6. doi: 10.3390/ijms241813733
PMCID:
PMC10530579
AbstractArticlePDF–2.8M
2.
Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia
Yu-Han H. Hsu, Greta Pintacuda, Ruize Liu, Eugeniu Nacu, April Kim, Kalliopi Tsafou, Natalie Petrossian, William Crotty, Jung Min Suh, Jackson Riseman, Jacqueline M. Martin, Julia C. Biagini, Daya Mena, Joshua K.T. Ching, Edyta Malolepsza, Taibo Li, Tarjinder Singh, Tian Ge, Shawn B. Egri, Benjamin Tanenbaum, Caroline R. Stanclift, Annie M. Apffel, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Stanley Global Asia Initiatives, Steven A. Carr, Monica Schenone, Jake Jaffe, Nadine Fornelos, Hailiang Huang, Kevin C. Eggan, Kasper Lage
iScience. 2023 May 19; 26(5): 106701. Published online 2023 Apr 18. doi: 10.1016/j.isci.2023.106701
PMCID:
PMC10189495
AbstractArticlePDF–5.3M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
Structural basis of the activation of a metabotropic GABA receptor
Hamidreza Shaye, Andrii Ishchenko, Jordy Homing Lam, Gye Won Han, Li Xue, Philippe Rondard, Jean-Philippe Pin, Vsevolod Katritch, Cornelius Gati, Vadim Cherezov
Nature. Author manuscript; available in PMC 2021 Apr 5.
Published in final edited form as: Nature. 2020 Aug; 584(7820): 298–303. Published online 2020 Jun 17. doi: 10.1038/s41586-020-2408-4
PMCID:
PMC8020835
AbstractArticlePDF–2.7M
5.
Structure of human GABAB receptor in an inactive state
Jinseo Park, Ziao Fu, Aurel Frangaj, Jonathan Liu, Lidia Mosyak, Tong Shen, Vesna N. Slavkovich, Kimberly M. Ray, Jaume Taura, Baohua Cao, Yong Geng, Hao Zuo, Yongjun Kou, Robert Grassucci, Shaoxia Chen, Zheng Liu, Xin Lin, Justin P. Williams, William J. Rice, Edward T. Eng, Rick K. Huang, Rajesh K. Soni, Brian Kloss, Zhiheng Yu, Jonathan A. Javitch, Wayne A. Hendrickson, Paul A. Slesinger, Matthias Quick, Joseph Graziano, Hongtao Yu, Oliver Fiehn, Oliver B. Clarke, Joachim Frank, Qing R. Fan
Nature. Author manuscript; available in PMC 2020 Dec 24.
Published in final edited form as: Nature. 2020 Aug; 584(7820): 304–309. Published online 2020 Jun 24. doi: 10.1038/s41586-020-2452-0
Correction in:
Nature. 2020 Jul; 583(7818): E29.
PMCID:
PMC7725281
AbstractArticlePDF–5.3M
6.
Structures of metabotropic GABAB receptor
Makaía M. Papasergi-Scott, Michael J. Robertson, Alpay B. Seven, Ouliana Panova, Jesper M. Mathiesen, Georgios Skiniotis
Nature. Author manuscript; available in PMC 2020 Dec 24.
Published in final edited form as: Nature. 2020 Aug; 584(7820): 310–314. Published online 2020 Jun 24. doi: 10.1038/s41586-020-2469-4
PMCID:
PMC7429364
AbstractArticlePDF–6.1M
7.
Tamalin, a PDZ Domain-Containing Protein, Links a Protein Complex Formation of Group 1 Metabotropic Glutamate Receptors and the Guanine Nucleotide Exchange Factor Cytohesins
Jun Kitano, Kouji Kimura, Yoshimitsu Yamazaki, Takeshi Soda, Ryuichi Shigemoto, Yoshiaki Nakajima, Shigetada Nakanishi
J Neurosci. 2002 Feb 15; 22(4): 1280–1289. doi: 10.1523/JNEUROSCI.22-04-01280.2002
PMCID:
PMC6757580
AbstractArticlePDF–529K
8.
Structural basis for auxiliary subunit KCTD16 regulation of the GABAB receptor
Hao Zuo, Ian Glaaser, Yulin Zhao, Igor Kurinov, Lidia Mosyak, Haonan Wang, Jonathan Liu, Jinseo Park, Aurel Frangaj, Emmanuel Sturchler, Ming Zhou, Patricia McDonald, Yong Geng, Paul A. Slesinger, Qing R. Fan
Proc Natl Acad Sci U S A. 2019 Apr 23; 116(17): 8370–8379. Published online 2019 Apr 10. doi: 10.1073/pnas.1903024116
PMCID:
PMC6486783
AbstractArticlePDF–2.6M
9.
Spatial Clustering of de Novo Missense Mutations Identifies Candidate Neurodevelopmental Disorder-Associated Genes
Stefan H. Lelieveld, Laurens Wiel, Hanka Venselaar, Rolph Pfundt, Gerrit Vriend, Joris A. Veltman, Han G. Brunner, Lisenka E.L.M. Vissers, Christian Gilissen
Am J Hum Genet. 2017 Sep 7; 101(3): 478–484. Published online 2017 Aug 31. doi: 10.1016/j.ajhg.2017.08.004
PMCID:
PMC5591029
AbstractArticlePDF–785K
10.
The Identification of Novel Proteins That Interact With the GLP-1 Receptor and Restrain its Activity
X. Huang, F. F. Dai, G. Gaisano, K. Giglou, J. Han, M. Zhang, S. Kittanakom, V. Wong, L. Wei, A. D. Showalter, K. W. Sloop, I. Stagljar, M. B. Wheeler
Mol Endocrinol. September 1, 2013; 27(9): 1550–1563. Published online 2013 Jul 17. doi: 10.1210/me.2013-1047
PMCID:
PMC5415235
AbstractArticle
11.
Systematic protein–protein interaction mapping for clinically relevant human GPCRs
Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar
Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430
PMCID:
PMC5371730
AbstractArticlePDF–4.1M
12.
Ligand-guided homology modelling of the GABAB2 subunit of the GABAB receptor
Thibaud Freyd, Dawid Warszycki, Stefan Mordalski, Andrzej J. Bojarski, Ingebrigt Sylte, Mari Gabrielsen
PLoS One. 2017; 12(3): e0173889. Published online 2017 Mar 21. doi: 10.1371/journal.pone.0173889
PMCID:
PMC5360267
AbstractArticlePDF–2.0M
13.
Post-endocytotic Deubiquitination and Degradation of the Metabotropic γ-Aminobutyric Acid Receptor by the Ubiquitin-specific Protease 14
Nicolas Lahaie, Michaela Kralikova, Laurent Prézeau, Jaroslav Blahos, Michel Bouvier
J Biol Chem. 2016 Mar 25; 291(13): 7156–7170. Published online 2016 Jan 27. doi: 10.1074/jbc.M115.686907
PMCID:
PMC4807296
AbstractArticlePDF–2.2M
14.
The Contribution of Rare and Common Variants in 30 Genes to Risk Nicotine Dependence
Jiekun Yang, Shaolin Wang, Zhongli Yang, Colin A. Hodgkinson, Polina Iarikova, Jennie Z. Ma, Thomas J. Payne, David Goldman, Ming D. Li
Mol Psychiatry. Author manuscript; available in PMC 2016 May 1.
Published in final edited form as: Mol Psychiatry. 2015 Nov; 20(11): 1467–1478. Published online 2014 Dec 2. doi: 10.1038/mp.2014.156
PMCID:
PMC4452458
AbstractArticlePDF–753K
15.
Identification of a Novel Protein Complex Containing ASIC1a and GABAA Receptors and Their Interregulation
Dongbo Zhao, Nannan Ning, Zhen Lei, Hua Sun, Chuanfei Wei, Dawei Chen, Jingxin Li
PLoS One. 2014; 9(6): e99735. Published online 2014 Jun 12. doi: 10.1371/journal.pone.0099735
PMCID:
PMC4055689
AbstractArticlePDF–3.3M
16.
Heterodimeric coiled-coil interactions of human GABAB receptor
Svetlana Burmakina, Yong Geng, Yan Chen, Qing R. Fan
Proc Natl Acad Sci U S A. 2014 May 13; 111(19): 6958–6963. Published online 2014 Apr 28. doi: 10.1073/pnas.1400081111
PMCID:
PMC4024898
AbstractArticlePDF–1.3M
17.
Proteasomal Degradation of γ-Aminobutyric AcidB Receptors Is Mediated by the Interaction of the GABAB2 C Terminus with the Proteasomal ATPase Rtp6 and Regulated by Neuronal Activity
Khaled Zemoura, Dietmar Benke
J Biol Chem. 2014 Mar 14; 289(11): 7738–7746. Published online 2014 Jan 30. doi: 10.1074/jbc.M113.541987
PMCID:
PMC3953284
AbstractArticlePDF–1.9M
18.
Structural mechanism of ligand activation in human GABAB receptor
Yong Geng, Martin Bush, Lidia Mosyak, Feng Wang, Qing R. Fan
Nature. Author manuscript; available in PMC 2014 Jun 12.
Published in final edited form as: Nature. 2013 Dec 12; 504(7479): 254–259. Published online 2013 Dec 4. doi: 10.1038/nature12725
PMCID:
PMC3865065
AbstractArticlePDF–2.0M
19.
Genome-wide Association Study Identifies New Susceptibility Loci for Posttraumatic Stress Disorder
Pingxing Xie, Henry R. Kranzler, Can Yang, Hongyu Zhao, Lindsay A. Farrer, Joel Gelernter
Biol Psychiatry. Author manuscript; available in PMC 2013 Nov 1.
Published in final edited form as: Biol Psychiatry. 2013 Nov 1; 74(9): 10.1016/j.biopsych.2013.04.013. Published online 2013 May 28. doi: 10.1016/j.biopsych.2013.04.013
PMCID:
PMC3810148
AbstractArticlePDF–319K
20.
γ-Aminobutyric Acid Type B (GABAB) Receptor Expression Is Needed for Inhibition of N-type (Cav2.2) Calcium Channels by Analgesic α-Conotoxins
Hartmut Cuny, Andrew de Faoite, Thuan G. Huynh, Takahiro Yasuda, Géza Berecki, David J. Adams
J Biol Chem. 2012 Jul 6; 287(28): 23948–23957. Published online 2012 May 21. doi: 10.1074/jbc.M112.342998
PMCID:
PMC3390670
AbstractArticlePDF–1.2M

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