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Select item 107177211.

Cardioprotective responses to aerobic exercise-induced physiological hypertrophy in zebrafish heart

Zhanglin Chen, Zuoqiong Zhou, Xiyang Peng, Chenchen Sun, Dong Yang, Chengli Li, Runkang Zhu, Ping Zhang, Lan Zheng, Changfa Tang

J Physiol Sci. 2021; 71: 33. Published online 2021 Nov 8. doi: 10.1186/s12576-021-00818-w

PMCID:: PMC10717721

Abstract Article PDF–5.2M

Select item 102188382.

Deletion of the foxO4 Gene Increases Hypoxia Tolerance in Zebrafish

Linlin Shi, Axin Zhang, Hong Liu, Huanling Wang

Int J Mol Sci. 2023 May; 24(10): 8942. Published online 2023 May 18. doi: 10.3390/ijms24108942

PMCID:: PMC10218838

Abstract Article PDF–3.3M

Select item 100660513.

Zebrafish ELL-associated factors Eaf1/2 modulate erythropoiesis via regulating gata1a expression and WNT signaling to facilitate hypoxia tolerance

WenYe Liu, ShuHui Lin, LingYa Li, ZhiPeng Tai, Jing-Xia Liu

Cell Regen. 2023 Dec; 12: 10. Published online 2023 Apr 1. doi: 10.1186/s13619-022-00154-3

PMCID:: PMC10066051

Abstract Article PDF–12M

Select item 94402944.

Ercc2/Xpd deficiency results in failure of digestive organ growth in zebrafish with elevated nucleolar stress

Jinmin Ma, Xuelian Shao, Fang Geng, Shuzhang Liang, Chunxiao Yu, Ruilin Zhang

iScience. 2022 Sep 16; 25(9): 104957. Published online 2022 Aug 17. doi: 10.1016/j.isci.2022.104957

PMCID:: PMC9440294

Abstract Article PDF–7.2M

Select item 92958025.

Reduced physiological plasticity in a fish adapted to stable temperatures

Rachael Morgan, Anna H. Andreassen, Eirik R. Åsheim, Mette H. Finnøen, Gunnar Dresler, Tore Brembu, Adrian Loh, Joanna J. Miest, Fredrik Jutfelt

Proc Natl Acad Sci U S A. 2022 May 31; 119(22): e2201919119. Published online 2022 May 26. doi: 10.1073/pnas.2201919119

PMCID:: PMC9295802

Abstract Article PDF–4.1M

Select item 92884326.

Estrogens revert neutrophil hyperplasia by inhibiting Hif1α-cMyb pathway in zebrafish myelodysplastic syndromes models

Xuexiao Li, Luping Wang, Xun Qin, Xiaohui Chen, Li Li, Zhibin Huang, Wenqing Zhang, Wei Liu

Cell Death Discov. 2022; 8: 323. Published online 2022 Jul 16. doi: 10.1038/s41420-022-01121-2

PMCID:: PMC9288432

Abstract Article PDF–4.9M

Select item 87531527.

Aquatic surface respiration improves survival during hypoxia in zebrafish (Danio rerio) lacking hypoxia-inducible factor 1-α

Milica Mandic, Kaitlyn Flear, Pearl Qiu, Yihang K. Pan, Steve F. Perry, Kathleen M. Gilmour

Proc Biol Sci. January 12, 2022; 289(1966): 20211863. Published online January 12, 2022. doi: 10.1098/rspb.2021.1863

PMCID:: PMC8753152

Abstract Article PDF–583K

Select item 86042728.

Accelerated loss of hypoxia response in zebrafish with familial Alzheimer’s disease-like mutation of presenilin 1

Morgan Newman, Hani Moussavi Nik, Greg T Sutherland, Nhi Hin, Woojin S Kim, Glenda M Halliday, Suman Jayadev, Carole Smith, Angela S Laird, Caitlin W Lucas, Thaksaon Kittipassorn, Dan J Peet, Michael Lardelli

Hum Mol Genet. 2020 Jul 15; 29(14): 2379–2394. Published online 2020 Jun 26. doi: 10.1093/hmg/ddaa119

PMCID:: PMC8604272

Abstract Article PDF–1.1M

Select item 85769579.

A lysosome-targeted dextran-doxorubicin nanodrug overcomes doxorubicin-induced chemoresistance of myeloid leukemia

Yunxin Zeng, Xinyu Zhang, Dongjun Lin, Xiaohui Feng, Yuye Liu, Zhengwen Fang, Weijian Zhang, Yu Chen, Meng Zhao, Jun Wu, Linjia Jiang

J Hematol Oncol. 2021; 14: 189. Published online 2021 Nov 8. doi: 10.1186/s13045-021-01199-8

PMCID:: PMC8576957

Abstract Article PDF–5.5M

Select item 852435810.

Targeted Degradation of Transcription Factors by TRAFTACs: TRAnscription Factor Targeting Chimeras

Kusal T. G. Samarasinghe, Saul Jaime-Figueroa, Michael Burgess, Dhanusha A. Nalawansha, Katherine Dai, Zhenyi Hu, Adrian Bebenek, Scott A. Holley, Craig M. Crews

Cell Chem Biol. Author manuscript; available in PMC 2021 Oct 19.

Published in final edited form as: Cell Chem Biol. 2021 May 20; 28(5): 648–661.e5. Published online 2021 Apr 8. doi: 10.1016/j.chembiol.2021.03.011

PMCID:: PMC8524358

Abstract Article PDF–2.1M

Select item 792992811.

Quantitative intravital imaging in zebrafish reveals in vivo dynamics of physiological-stress-induced mitophagy

Paul J. Wrighton, Arkadi Shwartz, Jin-Mi Heo, Eleanor D. Quenzer, Kyle A. LaBella, J. Wade Harper, Wolfram Goessling

J Cell Sci. 2021 Feb 15; 134(4): jcs256255. Published online 2021 Feb 22. doi: 10.1242/jcs.256255

PMCID:: PMC7929928

Abstract Article

Select item 756072312.

Specific cyprinid HIF isoforms contribute to cellular mitochondrial regulation

Jing Chen, Lihong Guan, Ming Zou, Shunping He, Dapeng Li, Wei Chi

Sci Rep. 2020; 10: 17246. Published online 2020 Oct 14. doi: 10.1038/s41598-020-74210-w

PMCID:: PMC7560723

Abstract Article PDF–2.6M

Select item 746480613.

Integrated Hypoxia Signaling and Oxidative Stress in Developmental Neurotoxicity of Benzo[a]Pyrene in Zebrafish Embryos

Yi-Chen Lin, Chang-Yi Wu, Chin-Hwa Hu, Tun-Wen Pai, Yet-Ran Chen, Wen-Der Wang

Antioxidants (Basel) 2020 Aug; 9(8): 731. Published online 2020 Aug 11. doi: 10.3390/antiox9080731

PMCID:: PMC7464806

Abstract Article PDF–4.2M

Select item 745845314.

Cystathione β-synthase regulates HIF-1α stability through persulfidation of PHD2

Anindya Dey, Shubhangi Prabhudesai, Yushan Zhang, Geeta Rao, Karthikeyan Thirugnanam, Md. Nazir Hossen, Shailendra Kumar Dhar Dwivedi, Ramani Ramchandran, Priyabrata Mukherjee, Resham Bhattacharya

Sci Adv. 2020 Jul; 6(27): eaaz8534. Published online 2020 Jul 3. doi: 10.1126/sciadv.aaz8534

PMCID:: PMC7458453

Abstract Article PDF–3.7M

Select item 742304915.

Hypoxia inducible factor-1α knockout does not impair acute thermal tolerance or heat hardening in zebrafish

William Joyce, Steve F. Perry

Biol Lett. 2020 Jul; 16(7): 20200292. Published online 2020 Jul 15. doi: 10.1098/rsbl.2020.0292

PMCID:: PMC7423049

Abstract Article PDF–538K

Select item 728736016.

Loss of hypoxia-inducible factor 1α affects hypoxia tolerance in larval and adult zebrafish (Danio rerio)

Milica Mandic, Carol Best, Steve F. Perry

Proc Biol Sci. 2020 May 27; 287(1927): 20200798. Published online 2020 May 27. doi: 10.1098/rspb.2020.0798

PMCID:: PMC7287360

Abstract Article PDF–435K

Select item 692013317.

Deletion of narfl leads to increased oxidative stress mediated abnormal angiogenesis and digestive organ defects in zebrafish

Jing Luo, Xiaokang Zhang, Siying He, Qiyong Lou, Gang Zhai, Chuang Shi, Zhan Yin, Fang Zheng

Redox Biol. 2020 Jan; 28: 101355. Published online 2019 Oct 23. doi: 10.1016/j.redox.2019.101355

PMCID:: PMC6920133

Abstract Article PDF–2.2M

Select item 681200718.

The NOTCH1-dependent HIF1α/VGLL4/IRF2BP2 oxygen sensing pathway triggers erythropoiesis terminal differentiation

Yiqin Wang, Xiaohui Liu, Baoshu Xie, Hao Yuan, Yiyue Zhang, Jun Zhu

Redox Biol. 2020 Jan; 28: 101313. Published online 2019 Sep 2. doi: 10.1016/j.redox.2019.101313

PMCID:: PMC6812007

Abstract Article PDF–5.3M

Select item 670782719.

Genetic compensation triggered by mutant mRNA degradation

Mohamed A. El-Brolosy, Zacharias Kontarakis, Andrea Rossi, Carsten Kuenne, Stefan Günther, Nana Fukuda, Khrievono Kikhi, Giulia L.M. Boezio, Carter Takacs, Shih-Lei Lai, Ryuichi Fukuda, Claudia Gerri, Antonio J. Giraldez, Didier Y.R. Stainier

Nature. Author manuscript; available in PMC 2019 Oct 3.

Published in final edited form as: Nature. 2019 May 7; 568(7751): 193–197. Published online 2019 Apr 3. doi: 10.1038/s41586-019-1064-z