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Select item 112174911.

Chromatin modifier Hmga2 promotes adult hematopoietic stem cell function and blood regeneration in stress conditions

Sho Kubota, Yuqi Sun, Mariko Morii, Jie Bai, Takako Ideue, Mayumi Hirayama, Supannika Sorin, Eerdunduleng, Takako Yokomizo-Nakano, Motomi Osato, Ai Hamashima, Mihoko Iimori, Kimi Araki, Terumasa Umemoto, Goro Sashida

EMBO J. 2024 Jul; 43(13): 2661–2684. Published online 2024 May 29. doi: 10.1038/s44318-024-00122-4

PMCID:: PMC11217491

Abstract Article PDF–4.0M

Select item 111313192.

Association of deletion polymorphism rs10573247 in the HMGA2 gene with the risk of breast cancer: bioinformatic and experimental analyses

Kolsoom Najibi, Mehdi Moghanibashi, Sirous Naeimi

World J Surg Oncol. 2024; 22: 142. Published online 2024 May 28. doi: 10.1186/s12957-024-03415-4

PMCID:: PMC11131319

Abstract Article PDF–2.3M

Select item 110639323.

Characterization of HMGA2 variants expands the spectrum of Silver-Russell syndrome

Avinaash V. Maharaj, Emily Cottrell, Thatchawan Thanasupawat, Sjoerd D. Joustra, Barbara Triggs-Raine, Masanobu Fujimoto, Sarina G. Kant, Danielle van der Kaay, Agnes Clement-de Boers, Alice S. Brooks, Gabriel Amador Aguirre, Irene Martín del Estal, María Inmaculada Castilla de Cortázar Larrea, Ahmed Massoud, Hermine A. van Duyvenvoorde, Christiaan De Bruin, Vivian Hwa, Thomas Klonisch, Sabine Hombach-Klonisch, Helen L. Storr

JCI Insight. 2024 Mar 22; 9(6): e169425. Published online 2024 Mar 22. doi: 10.1172/jci.insight.169425

PMCID:: PMC11063932

Abstract Article PDF–2.7M

Select item 107814644.

LncRNA HAGLROS contribute to papillary thyroid cancer progression by modulating miR-206/HMGA2 expression

Zhaohui Zeng, Shengtao Tang, Liping Chen, Haiwen Hou, Yuan Liu, Juhui Li

Aging (Albany NY) 2023 Dec 31; 15(24): 14930–14944. Published online 2023 Dec 18. doi: 10.18632/aging.205321

PMCID:: PMC10781464

Abstract Article PDF–1.9M

Select item 105658765.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 105270486.

ELAC2 is a functional prostate cancer risk allele

Steven Blinka, Rashmi Mishra, Andrew C. Hsieh

Trends Mol Med. Author manuscript; available in PMC 2024 Aug 1.

Published in final edited form as: Trends Mol Med. 2023 Aug; 29(8): 586–588. Published online 2023 Jun 21. doi: 10.1016/j.molmed.2023.06.002

PMCID:: PMC10527048

Abstract Article PDF–312K

Select item 103582037.

Proteomic analysis identifies HMGA2 as a novel biomarker of overall survival in papillary renal cell carcinoma

Tian Wei, Huiya Xu, Huishan Liang, Yating Lian, Huiyu Chen, Zhangyi Zheng, Minghui Zhong, Junfeng Liu, Ran Wang, Fen Wang

Cancer Med. 2023 Jul; 12(13): 14851–14864. Published online 2023 Jun 7. doi: 10.1002/cam4.6077

PMCID:: PMC10358203

Abstract Article PDF–21M

Select item 103415548.

Unraveling the Roles of miR-204-5p and HMGA2 in Papillary Thyroid Cancer Tumorigenesis

Cindy Van Branteghem, Alice Augenlicht, Pieter Demetter, Ligia Craciun, Carine Maenhaut

Int J Mol Sci. 2023 Jul; 24(13): 10764. Published online 2023 Jun 28. doi: 10.3390/ijms241310764

PMCID:: PMC10341554

Abstract Article PDF–8.4M

Select item 102799139.

AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity

Mario Ruiz, Ranjan Devkota, Delaney Kaper, Hanna Ruhanen, Kiran Busayavalasa, Uroš Radović, Marcus Henricsson, Reijo Käkelä, Jan Borén, Marc Pilon

J Biol Chem. 2023 Jun; 299(6): 104799. Published online 2023 May 8. doi: 10.1016/j.jbc.2023.104799

PMCID:: PMC10279913

Abstract Article PDF–4.1M

Select item 1023742210.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1015161511.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 1002663812.

Fusion of the High-mobility Group AT-Hook 2 (HMGA2) and the Gelsolin (GSN) Genes in Lipomas With t(9;12)(q33;q14) Chromosomal Translocation

IOANNIS PANAGOPOULOS, KRISTIN ANDERSEN, MARTA BRUNETTI, LUDMILA GORUNOVA, MARIUS LUND-IVERSEN, FRANCESCA MICCI, SVERRE HEIM

In Vivo. 2023 Mar-Apr; 37(2): 524–530. Published online 2023 Mar 3. doi: 10.21873/invivo.13110

PMCID:: PMC10026638

Abstract Article PDF–2.2M

Select item 996687513.

Nuclear High Mobility Group A2 (HMGA2) Interactome Revealed by Biotin Proximity Labeling

Antoine Gaudreau-Lapierre, Thomas Klonisch, Hannah Nicolas, Thatchawan Thanasupawat, Laura Trinkle-Mulcahy, Sabine Hombach-Klonisch

Int J Mol Sci. 2023 Feb; 24(4): 4246. Published online 2023 Feb 20. doi: 10.3390/ijms24044246

PMCID:: PMC9966875

Abstract Article PDF–2.4M

Select item 980751914.

HMGA2 drives the IGFBP1/AKT pathway to counteract the increase in P27KIP1 protein levels in mtDNA/RNA‐less cancer cells

Tsuyoshi Maruyama, Koji Saito, Masato Higurashi, Fumihiro Ishikawa, Yohko Kohno, Kazunori Mori, Motoko Shibanuma

Cancer Sci. 2023 Jan; 114(1): 152–163. Published online 2022 Sep 26. doi: 10.1111/cas.15582

PMCID:: PMC9807519

Abstract Article PDF–1.9M

Select item 966758615.

ARPC1B promotes mesenchymal phenotype maintenance and radiotherapy resistance by blocking TRIM21-mediated degradation of IFI16 and HuR in glioma stem cells

Zijie Gao, Jianye Xu, Yang Fan, Zongpu Zhang, Huizhi Wang, Mingyu Qian, Ping Zhang, Lin Deng, Jie Shen, Hao Xue, Rongrong Zhao, Teng Zhou, Xing Guo, Gang Li

J Exp Clin Cancer Res. 2022; 41: 323. Published online 2022 Nov 16. doi: 10.1186/s13046-022-02526-8

PMCID:: PMC9667586

Abstract Article PDF–11M

Select item 957659616.

Exosomal HMGA2 protein from EBV-positive NPC cells destroys vascular endothelial barriers and induces endothelial-to-mesenchymal transition to promote metastasis

Deng-Ke Li, Xing-Rui Chen, Li-Na Wang, Jia-Hong Wang, Ji-Ke Li, Zi-Ying Zhou, Xin Li, Lin-Bo Cai, Shui-Sheng Zhong, Jing-Jing Zhang, Yu-Mei Zeng, Qian-Bing Zhang, Xiao-Yan Fu, Xiao-Ming Lyu, Min-Ying Li, Zhong-Xi Huang, Kai-Tai Yao

Cancer Gene Ther. 2022; 29(10): 1439–1451. Published online 2022 Apr 6. doi: 10.1038/s41417-022-00453-6