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Select item 111481871.

TLR7-dependent eosinophil degranulation links psoriatic skin inflammation to small intestinal inflammatory changes in mice

Hee Joo Kim, Jinsun Jang, Kunhee Na, Eun-Hui Lee, Hyeon-Jung Gu, Yoon Hee Lim, Seul-A Joo, Seung Eun Baek, Joo-Young Roh, Han-Joo Maeng, Yun Hak Kim, Young-Jae Lee, Byung-Chul Oh, YunJae Jung

Exp Mol Med. 2024 May; 56(5): 1164–1177. Published online 2024 May 1. doi: 10.1038/s12276-024-01225-y

PMCID:: PMC11148187

Abstract Article PDF–7.7M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 104780073.

Migration-induced cell shattering due to DOCK8-deficiency causes a type-2 biased helper T cell response

Caitlin Schneider, Connie Shen, Angelica A. Gopal, Todd Douglas, Benjamin Forestell, Keith D. Kauffman, Dakota Rogers, Patricio Artusa, Qian Zhang, Huie Jing, Alexandra F. Freeman, Daniel L. Barber, Irah L. King, Maya Saleh, Paul W. Wiseman, Helen C. Su, Judith N. Mandl

Nat Immunol. Author manuscript; available in PMC 2023 Sep 5.

Published in final edited form as: Nat Immunol. 2020 Dec; 21(12): 1528–1539. Published online 2020 Oct 5. doi: 10.1038/s41590-020-0795-1

PMCID:: PMC10478007

Abstract Article PDF–2.2M

Select item 99296084.

Obesity control by SHIP inhibition requires pan-paralog inhibition and an intact eosinophil compartment

Sandra Fernandes, Neetu Srivastava, Chiara Pedicone, Raki Sudan, Elizabeth A. Luke, Otto M. Dungan, Angela Pacherille, Shea T. Meyer, Shawn Dormann, Stéphane Schurmans, Benedict J. Chambers, John D. Chisholm, William G. Kerr

iScience. 2023 Feb 17; 26(2): 106071. Published online 2023 Jan 28. doi: 10.1016/j.isci.2023.106071

PMCID:: PMC9929608

Abstract Article PDF–2.4M

Select item 89178235.

Thymic stromal lymphopoietin induces adipose loss through sebum hypersecretion

Ruth Choa, Junichiro Tohyama, Shogo Wada, Hu Meng, Jian Hu, Mariko Okumura, Rebecca M. May, Tanner F. Robertson, Ruth-Anne Langan Pai, Arben Nace, Christian Hopkins, Elizabeth A. Jacobsen, Malay Haldar, Garret A. FitzGerald, Edward M. Behrens, Andy J. Minn, Patrick Seale, George Cotsarelis, Brian Kim, John T. Seykora, Mingyao Li, Zoltan Arany, Taku Kambayashi

Science. Author manuscript; available in PMC 2022 Mar 12.

Published in final edited form as: Science. 2021 Jul 30; 373(6554): eabd2893. doi: 10.1126/science.abd2893

PMCID:: PMC8917823

Abstract Article PDF–1.8M

Select item 85957556.

Enteric pathogens induce tissue tolerance and prevent neuronal loss from subsequent infections

Tomasz Ahrends, Begüm Aydin, Fanny Matheis, Cajsa H. Classon, François Marchildon, Gláucia C. Furtado, Sérgio A. Lira, Daniel Mucida

Cell. Author manuscript; available in PMC 2022 Nov 11.

Published in final edited form as: Cell. 2021 Nov 11; 184(23): 5715–5727.e12. Published online 2021 Oct 29. doi: 10.1016/j.cell.2021.10.004

PMCID:: PMC8595755

Abstract Article PDF–2.4M

Select item 84108977.

Basophils promote barrier dysfunction and resolution in the atopic skin

Christophe Pellefigues, Karmella Naidoo, Palak Mehta, Alfonso J. Schmidt, Ferdinand Jagot, Elsa Roussel, Alissa Cait, Bibek Yumnam, Sally Chappell, Kimberley Meijlink, Mali Camberis, Jean X. Jiang, Gavin Painter, Kara Filbey, Özge Uluçkan, Olivier Gasser, Graham Le Gros

J Allergy Clin Immunol. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: J Allergy Clin Immunol. 2021 Sep; 148(3): 799–812.e10. Published online 2021 Mar 2. doi: 10.1016/j.jaci.2021.02.018

PMCID:: PMC8410897

Abstract Article PDF–3.1M

Select item 81605048.

ATG5 promotes eosinopoiesis but inhibits eosinophil effector functions

Nina Germic, Aref Hosseini, Darko Stojkov, Kevin Oberson, Meike Claus, Charaf Benarafa, Sara Calzavarini, Anne Angelillo-Scherrer, Isabelle C. Arnold, Anne Müller, Carsten Riether, Shida Yousefi, Hans-Uwe Simon

Blood. 2021 May 27; 137(21): 2958–2969. Prepublished online 2021 Feb 17. doi: 10.1182/blood.2020010208

PMCID:: PMC8160504

Abstract Article

Select item 80118879.

UDP-glucose and P2Y₁₄ receptor amplify allergen-induced airway eosinophilia

Tadeusz P. Karcz, Gregory S. Whitehead, Keiko Nakano, Hideki Nakano, Sara A. Grimm, Jason G. Williams, Leesa J. Deterding, Kenneth A. Jacobson, Donald N. Cook

J Clin Invest. 2021 Apr 1; 131(7): e140709. Published online 2021 Apr 1. doi: 10.1172/JCI140709

PMCID:: PMC8011887

Abstract Article PDF–4.0M

Select item 793877010.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 774502011.

Eosinophils improve cardiac function after myocardial infarction

Jing Liu, Chongzhe Yang, Tianxiao Liu, Zhiyong Deng, Wenqian Fang, Xian Zhang, Jie Li, Qin Huang, Conglin Liu, Yunzhe Wang, Dafeng Yang, Galina K. Sukhova, Jes S. Lindholt, Axel Diederichsen, Lars M. Rasmussen, Dazhu Li, Gail Newton, Francis W. Luscinskas, Lijun Liu, Peter Libby, Jing Wang, Junli Guo, Guo-Ping Shi

Nat Commun. 2020; 11: 6396. Published online 2020 Dec 16. doi: 10.1038/s41467-020-19297-5

PMCID:: PMC7745020

Abstract Article PDF–11M

Select item 690992812.

TLR-7 stress signaling in differentiating and mature eosinophils is mediated by the prolyl isomerase Pin1

Zhong-Jian Shen, Jie Hu, Venkatesh Kashi, Yury A Bochkov, James E. Gern, James S. Malter

J Immunol. Author manuscript; available in PMC 2019 Dec 15.

Published in final edited form as: J Immunol. 2018 Dec 15; 201(12): 3503–3513. Published online 2018 Nov 5. doi: 10.4049/jimmunol.1800881

PMCID:: PMC6909928

Abstract Article PDF–840K

Select item 690880613.

Eosinophil-platelet interactions promote atherosclerosis and stabilize thrombosis with eosinophil extracellular traps

Charlotte Marx, Julia Novotny, Danby Salbeck, Katie R. Zellner, Leo Nicolai, Kami Pekayvaz, Badr Kilani, Sven Stockhausen, Niklas Bürgener, Danny Kupka, Thomas J. Stocker, Ludwig T. Weckbach, Joachim Pircher, Markus Moser, Michael Joner, Walter Desmet, Tom Adriaenssens, Franz-Josef Neumann, Anthony H. Gerschlick, Jurrien M. ten Berg, Michael Lorenz, Konstantin Stark

Blood. 2019 Nov 21; 134(21): 1859–1872. Prepublished online 2019 Sep 3. doi: 10.1182/blood.2019000518

PMCID:: PMC6908806

Abstract Article

Select item 654351814.

Trib1 regulates eosinophil lineage commitment and identity by restraining the neutrophil program

Ethan A. Mack, Sarah J. Stein, Kelly S. Rome, Lanwei Xu, Gerald B. Wertheim, Rossana C. N. Melo, Warren S. Pear

Blood. 2019 May 30; 133(22): 2413–2426. Prepublished online 2019 Mar 27. doi: 10.1182/blood.2018872218

PMCID:: PMC6543518

Abstract Article

Select item 651387115.

Intravital imaging allows real-time characterization of tissue resident eosinophils

Andrew Chojnacki, Katarzyna Wojcik, Björn Petri, Gurpreet Aulakh, Elizabeth A. Jacobsen, William E. LeSuer, Pina Colarusso, Kamala D. Patel

Commun Biol. 2019; 2: 181. Published online 2019 May 13. doi: 10.1038/s42003-019-0425-3

PMCID:: PMC6513871

Abstract Article PDF–6.2M

Select item 639737716.

Peroxidasin and eosinophil peroxidase, but not myeloperoxidase, contribute to renal fibrosis in the murine unilateral ureteral obstruction model

Selene Colon, Haiyan Luan, Yan Liu, Cameron Meyer, Leslie Gewin, Gautam Bhave

Am J Physiol Renal Physiol. 2019 Feb 1; 316(2): F360–F371. Published online 2018 Dec 19. doi: 10.1152/ajprenal.00291.2018

PMCID:: PMC6397377

Abstract Article

Select item 631008517.

Impact of eosinophil-peroxidase (EPX) deficiency on eosinophil structure and function in mouse airways

Caroline M. Percopo, Julia O. Krumholz, Elizabeth R. Fischer, Laura S. Kraemer, Michelle Ma, Karen Laky, Helene F. Rosenberg

J Leukoc Biol. Author manuscript; available in PMC 2020 Jan 1.

Published in final edited form as: J Leukoc Biol. 2019 Jan; 105(1): 151–161. Published online 2018 Oct 4. doi: 10.1002/JLB.3AB0318-090RR

PMCID:: PMC6310085

Abstract Article PDF–767K

Select item 612377418.

Vesicle-associated membrane protein 7-mediated eosinophil degranulation promotes allergic airway inflammation in mice

Lian Willetts, Lindsey C. Felix, Elizabeth A. Jacobsen, Lakshmi Puttagunta, Rachel M. Condjella, Katie R. Zellner, Sergei I. Ochkur, John D. Kim, Huijun Luo, Nancy A. Lee, James J. Lee, Redwan Moqbel, Paige Lacy

Commun Biol. 2018; 1: 83. Published online 2018 Jun 29. doi: 10.1038/s42003-018-0081-z

PMCID:: PMC6123774

Abstract Article PDF–1.4M

Select item 608090719.

Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation

Isabelle C. Arnold, Mariela Artola-Borán, Paulino Tallón de Lara, Andreas Kyburz, Christian Taube, Karen Ottemann, Maries van den Broek, Shida Yousefi, Hans-Uwe Simon, Anne Müller

J Exp Med. 2018 Aug 6; 215(8): 2055–2072. doi: 10.1084/jem.20172049

PMCID:: PMC6080907

Abstract Article PDF–4.0M

Select item 601336120.

Characterization of a novel mouse strain expressing human Siglec-8 only on eosinophils

Jeremy A. O’Sullivan, Yadong Wei, Daniela J. Carroll, Liliana Moreno-Vinasco, Yun Cao, Fengrui Zhang, James. J. Lee, Zhou Zhu, Bruce S. Bochner

J Leukoc Biol. Author manuscript; available in PMC 2019 Jul 1.

Published in final edited form as: J Leukoc Biol. 2018 Jul; 104(1): 11–19. Published online 2018 Mar 30. doi: 10.1002/JLB.2HI0917-391R

PMCID:: PMC6013361

Abstract Article PDF–1.0M

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