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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107693502.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 107591773.

Diacylglycerol kinase-ε is S-palmitoylated on cysteine in the cytoplasmic end of its N-terminal transmembrane fragment

Gabriela Traczyk, Aneta Hromada-Judycka, Anna Świątkowska, Julia Wiśniewska, Anna Ciesielska, Katarzyna Kwiatkowska

J Lipid Res. 2024 Jan; 65(1): 100480. Published online 2023 Nov 24. doi: 10.1016/j.jlr.2023.100480

PMCID:: PMC10759177

Abstract Article PDF–4.1M

Select item 91547604.

Diacylglycerol kinase epsilon protects against renal ischemia/reperfusion injury in mice through Krüppel-like factor 15/klotho pathway

Ziying Wang, Zhuanli Zhou, Yanan Zhang, Fuwen Zuo, Junyao Du, Mingwei Wang, Muchen Hu, Yu Sun, Xiaojie Wang, Min Liu, Yan Zhang, Wei Tang, Fan Yi

Ren Fail. 2022; 44(1): 902–913. Published online 2022 May 26. doi: 10.1080/0886022X.2022.2079524

PMCID:: PMC9154760

Abstract Article PDF–4.2M

Select item 82622935.

Loss of diacylglycerol kinase ε causes thrombotic microangiopathy by impairing endothelial VEGFA signaling

Dingxiao Liu, Qiong Ding, Dao-Fu Dai, Biswajit Padhy, Manasa K. Nayak, Can Li, Madison Purvis, Heng Jin, Chang Shu, Anil K. Chauhan, Chou-Long Huang, Massimo Attanasio

JCI Insight. 2021 May 10; 6(9): e146959. Published online 2021 May 10. doi: 10.1172/jci.insight.146959

PMCID:: PMC8262293

Abstract Article PDF–9.0M

Select item 74159916.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 72950337.

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant

Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely

Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089

PMCID:: PMC7295033

Abstract Article PDF–2.7M

Select item 54086098.

Diacylglycerol kinase ε deficiency preserves glucose tolerance and modulates lipid metabolism in obese mice

Louise Mannerås-Holm, Milena Schönke, Joseph T. Brozinick, Laurène Vetterli, Hai-Hoang Bui, Philip Sanders, Emmani B. M. Nascimento, Marie Björnholm, Alexander V. Chibalin, Juleen R. Zierath

J Lipid Res. 2017 May; 58(5): 907–915. Published online 2017 Apr 28. doi: 10.1194/jlr.M074443

PMCID:: PMC5408609

Abstract Article PDF–935K

Select item 53812269.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 506748610.

Diacylglycerol Kinase-ε: Properties and Biological Roles

Richard M. Epand, Vincent So, William Jennings, Bijendra Khadka, Radhey S. Gupta, Mathieu Lemaire

Front Cell Dev Biol. 2016; 4: 112. Published online 2016 Oct 18. doi: 10.3389/fcell.2016.00112

PMCID:: PMC5067486

Abstract Article PDF–3.4M

Select item 486731011.

Loss of diacylglycerol kinase epsilon in mice causes endothelial distress and impairs glomerular Cox-2 and PGE₂ production

Jili Zhu, Moumita Chaki, Dongmei Lu, Chongyu Ren, Shan-Shan Wang, Alysha Rauhauser, Binghua Li, Susan Zimmerman, Bokkyoo Jun, Yong Du, Komal Vadnagara, Hanquin Wang, Sarah Elhadi, Richard J. Quigg, Matthew K. Topham, Chandra Mohan, Fatih Ozaltin, Xin J. Zhou, Denise K. Marciano, Nicolas G. Bazan, Massimo Attanasio

Am J Physiol Renal Physiol. 2016 May 1; 310(9): F895–F908. Published online 2016 Feb 17. doi: 10.1152/ajprenal.00431.2015

PMCID:: PMC4867310

Abstract Article

Select item 422349112.

Progesterone Receptor Membrane Component 1 Is a Functional Part of the Glucagon-like Peptide-1 (GLP-1) Receptor Complex in Pancreatic β Cells

Ming Zhang, Mélanie Robitaille, Aaron D. Showalter, Xinyi Huang, Ying Liu, Alpana Bhattacharjee, Francis S. Willard, Junfeng Han, Sean Froese, Li Wei, Herbert Y. Gaisano, Stéphane Angers, Kyle W. Sloop, Feihan F. Dai, Michael B. Wheeler

Mol Cell Proteomics. 2014 Nov; 13(11): 3049–3062. Published online 2014 Jul 20. doi: 10.1074/mcp.M114.040196

PMCID:: PMC4223491

Abstract Article PDF–3.1M

Select item 357241013.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 337554214.

Inhibition of Lipid Signaling Enzyme Diacylglycerol Kinase ϵ Attenuates Mutant Huntingtin Toxicity

Ningzhe Zhang, Bensheng Li, Ismael Al-Ramahi, Xin Cong, Jason M. Held, Eugene Kim, Juan Botas, Bradford W. Gibson, Lisa M. Ellerby

J Biol Chem. 2012 Jun 15; 287(25): 21204–21213. Published online 2012 Apr 16. doi: 10.1074/jbc.M111.321661

PMCID:: PMC3375542

Abstract Article PDF–1.9M

Select item 319677315.

Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development

Alejandro López-Juárez, Sara Morales-Lázaro, Roberto Sánchez-Sánchez, Manjula Sunkara, Hilda Lomelí, Iván Velasco, Andrew J. Morris, Diana Escalante-Alcalde

Glia. Author manuscript; available in PMC 2012 Jul 6.

Published in final edited form as: Glia. 2011 Apr; 59(4): 577–589. Published online 2011 Jan 6. doi: 10.1002/glia.21126

PMCID:: PMC3196773

Abstract Article PDF–8.2M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 280576717.

Molecular Species of Phosphatidylinositol-Cycle Intermediates in the Endoplasmic Reticulum and Plasma Membrane

Yulia V. Shulga, David S. Myers, Pavlina T. Ivanova, Stephen B. Milne, H. Alex Brown, Matthew K. Topham, Richard M. Epand

Biochemistry. Author manuscript; available in PMC 2011 Jan 19.

Published in final edited form as: Biochemistry. 2010 Jan 19; 49(2): 312–317. doi: 10.1021/bi901551e

PMCID:: PMC2805767

Abstract Article PDF–1.4M

Select item 278150618.

Diacylglycerol Kinase ϵ Is Selective for Both Acyl Chains of Phosphatidic Acid or Diacylglycerol

Michael Lung, Yulia V. Shulga, Pavlina T. Ivanova, David S. Myers, Stephen B. Milne, H. Alex Brown, Matthew K. Topham, Richard M. Epand

J Biol Chem. 2009 Nov 6; 284(45): 31062–31073. Published online 2009 Sep 10. doi: 10.1074/jbc.M109.050617

PMCID:: PMC2781506

Abstract Article PDF–2.2M

Select item 274445819.

Dramatic Differences in the Roles in Lipid Metabolism Of Two Isoforms of Diacylglycerol Kinase

Stephen B. Milne, Pavlina T. Ivanova, Michelle D. Armstrong, David S. Myers, Jovana Lubarda, Yulia V. Shulga, Matthew K. Topham, H. Alex Brown, Richard M. Epand

Biochemistry. Author manuscript; available in PMC 2009 Sep 15.

Published in final edited form as: Biochemistry. 2008 Sep 9; 47(36): 9372–9379. Published online 2008 Aug 15. doi: 10.1021/bi800492c

PMCID:: PMC2744458

Abstract Article PDF–2.8M

Select item 255627020.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

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