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Items: 1 to 20 of 229

1.
Impact of aquaporin-4 and CD11c + microglia in the development of ependymal cells in the aqueduct: inferences to hydrocephalus
Francisco Mayo, Lourdes González-Vinceiro, Laura Hiraldo-González, Francisco D. Rodríguez-Gómez, Claudia Calle-Castillejo, Manuel Mayo, Vanina Netti, Reposo Ramírez-Lorca, Miriam Echevarría
Fluids Barriers CNS. 2024; 21: 53. Published online 2024 Jul 2. doi: 10.1186/s12987-024-00548-2
PMCID:
PMC11221146
AbstractArticlePDF–11M
2.
Macroscopic changes in aquaporin-4 underlie blast traumatic brain injury-related impairment in glymphatic function
Molly Braun, Mathew Sevao, Samantha A Keil, Elizabeth Gino, Marie X Wang, Janet Lee, Mariya A Haveliwala, Emily Klein, Sanjana Agarwal, Taylor Pedersen, C Harker Rhodes, Deidre Jansson, David Cook, Elaine Peskind, Daniel P Perl, Juan Piantino, Abigail G Schindler, Jeffrey J Iliff
Brain. 2024 Jun; 147(6): 2214–2229. Published online 2024 May 28. doi: 10.1093/brain/awae065
PMCID:
PMC11146423
AbstractArticlePDF–52M
3.
NHH promotes Sepsis-associated Encephalopathy with the expression of AQP4 in astrocytes through the gut-brain Axis
Lina Zhao, Zhen Zhang, Pei Wang, Nannan Zhang, Hao shen, Hening Wu, Zhiyong Wei, Fei Yang, Yunying Wang, Zhijie Yu, Haibo Li, Zhanfei Hu, Hongyan Zhai, Zhiwei Wang, Fuhong Su, Keliang Xie, Yun Li
J Neuroinflammation. 2024; 21: 138. Published online 2024 May 27. doi: 10.1186/s12974-024-03135-2
PMCID:
PMC11131257
AbstractArticlePDF–16M
4.
Role of aquaporin-4 polarization in extracellular solute clearance
Laura Bojarskaite, Sahar Nafari, Anne Katrine Ravnanger, Mina Martine Frey, Nadia Skauli, Knut Sindre Åbjørsbråten, Lena Catherine Roth, Mahmood Amiry-Moghaddam, Erlend A. Nagelhus, Ole Petter Ottersen, Inger Lise Bogen, Anna E. Thoren, Rune Enger
Fluids Barriers CNS. 2024; 21: 28. Published online 2024 Mar 26. doi: 10.1186/s12987-024-00527-7
PMCID:
PMC10964559
AbstractArticlePDF–2.4M
5.
Deletion of aquaporin‐4 improves capillary blood flow distribution in brain edema
Luca Bordoni, Anna E. Thoren, Eugenio Gutiérrez‐Jiménez, Knut S. Åbjørsbråten, Daniel M. Bjørnstad, Wannan Tang, Mette Stern, Leif Østergaard, Erlend A. Nagelhus, Sebastian Frische, Ole P. Ottersen, Rune Enger
Glia. 2023 Nov; 71(11): 2559–2572. Published online 2023 Jul 13. doi: 10.1002/glia.24439
PMCID:
PMC10952478
AbstractArticlePDF–5.3M
6.
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4
Ali Maisam Afzali, Lucy Nirschl, Christopher Sie, Monika Pfaller, Oleksii Ulianov, Tobias Hassler, Christine Federle, Elisabetta Petrozziello, Sudhakar Reddy Kalluri, Hsin Hsiang Chen, Sofia Tyystjärvi, Andreas Muschaweckh, Katja Lammens, Claire Delbridge, Andreas Büttner, Katja Steiger, Gönül Seyhan, Ole Petter Ottersen, Rupert Öllinger, Roland Rad, Sebastian Jarosch, Adrian Straub, Anton Mühlbauer, Simon Grassmann, Bernhard Hemmer, Jan P. Böttcher, Ingrid Wagner, Mario Kreutzfeldt, Doron Merkler, Irene Bonafonte Pardàs, Marc Schmidt Supprian, Veit R. Buchholz, Sylvia Heink, Dirk H. Busch, Ludger Klein, Thomas Korn
Nature. 2024; 627(8003): 407–415. Published online 2024 Feb 21. doi: 10.1038/s41586-024-07079-8
PMCID:
PMC10937377
AbstractArticlePDF–11M
7.
Water channel aquaporin 4 is required for T cell receptor mediated lymphocyte activation
Michael Nicosia, Juyeun Lee, Ashley Beavers, Danielle Kish, George W. Farr, Paul R. McGuirk, Marc F. Pelletier, Justin D. Lathia, Robert L. Fairchild, Anna Valujskikh
J Leukoc Biol. Author manuscript; available in PMC 2024 Feb 7.
Published in final edited form as: J Leukoc Biol. 2023 Jun 1; 113(6): 544–554. doi: 10.1093/jleuko/qiad010
PMCID:
PMC10848298
AbstractArticlePDF–2.0M
8.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
9.
Evaluation of gliovascular functions of AQP4 readthrough isoforms
Shayna M. Mueller, Kelli McFarland White, Stuart B. Fass, Siyu Chen, Zhan Shi, Xia Ge, John A. Engelbach, Seana H. Gaines, Annie R. Bice, Michael J. Vasek, Joel R. Garbow, Joseph P. Culver, Zila Martinez-Lozada, Martine Cohen-Salmon, Joseph D. Dougherty, Darshan Sapkota
Front Cell Neurosci. 2023; 17: 1272391. Published online 2023 Nov 23. doi: 10.3389/fncel.2023.1272391
PMCID:
PMC10701521
AbstractArticlePDF–3.7M
10.
PRELP secreted from mural cells protects the function of blood brain barrier through regulation of endothelial cell-cell integrity
Hongorzul Davaapil, Jack Hopkins, Nadia Bonnin, Vasiliki Papadaki, Alex Leung, Hirofumi Kosuge, Takumi Tashima, Makoto Nakakido, Ryohei Sekido, Kouhei Tsumoto, Mandeep S. Sagoo, Shin-Ichi Ohnuma
Front Cell Dev Biol. 2023; 11: 1147625. Published online 2023 Oct 23. doi: 10.3389/fcell.2023.1147625
PMCID:
PMC10626469
AbstractArticlePDF–4.5M
11.
Preconditioned extracellular vesicles from hypoxic microglia reduce poststroke AQP4 depolarization, disturbed cerebrospinal fluid flow, astrogliosis, and neuroinflammation
Wenqiang Xin, Yongli Pan, Wei Wei, Lars Tatenhorst, Irina Graf, Aurel Popa-Wagner, Stefan T Gerner, Sabine Huber, Ertugrul Kilic, Dirk M Hermann, Mathias Bähr, Hagen B Huttner, Thorsten R Doeppner
Theranostics. 2023; 13(12): 4197–4216. Published online 2023 Jul 24. doi: 10.7150/thno.84059
PMCID:
PMC10405850
AbstractArticlePDF–13M
12.
Evaluation of gliovascular functions of Aqp4 readthrough isoforms
Shayna M. Mueller, Kelli McFarland White, Stuart B. Fass, Siyu Chen, Zhan Shi, Xia Ge, John A. Engelbach, Seana H Gaines, Annie R Bice, Michael J. Vasek, Joel R. Garbow, Joseph P. Culver, Zila Martinez-Lozada, Martine Cohen-Salmon, Joseph D. Dougherty, Darshan Sapkota
Version 1. bioRxiv. Preprint. 2023 Jul 25. doi: 10.1101/2023.07.21.549379
Published in:
Front Cell Neurosci. 2023; 17: 1272391.
PMCID:
PMC10401933
AbstractArticlePDF–38M
13.
Stimulated Raman scattering microscopy reveals a unique and steady nature of brain water dynamics
Takanori Shinotsuka, Tsuyoshi Miyazawa, Keiko Karasawa, Yasuyuki Ozeki, Masato Yasui, Mutsuo Nuriya
Cell Rep Methods. 2023 Jul 24; 3(7): 100519. Published online 2023 Jul 5. doi: 10.1016/j.crmeth.2023.100519
PMCID:
PMC10391342
AbstractArticlePDF–7.4M
14.
T cell deletional tolerance restricts AQP4 but not MOG CNS autoimmunity
Sharon A. Sagan, Zahra Moinfar, Carson E. Moseley, Ravi Dandekar, Collin M. Spencer, Alan S. Verkman, Ole Petter Ottersen, Raymond A. Sobel, John Sidney, Alessandro Sette, Mark S. Anderson, Lawrence Steinman, Michael R. Wilson, Joseph J. Sabatino, Jr., Scott S. Zamvil
Proc Natl Acad Sci U S A. 2023 Jul 25; 120(30): e2306572120. Published online 2023 Jul 18. doi: 10.1073/pnas.2306572120
PMCID:
PMC10372680
AbstractArticlePDF–1.3M
15.
High-intensity interval training ameliorates Alzheimer's disease-like pathology by regulating astrocyte phenotype-associated AQP4 polarization
Shu Feng, Chongyun Wu, Peibin Zou, Qianting Deng, Zhe Chen, Meng Li, Ling Zhu, Fanghui Li, Timon Cheng-Yi Liu, Rui Duan, Luodan Yang
Theranostics. 2023; 13(10): 3434–3450. Published online 2023 Jun 4. doi: 10.7150/thno.81951
PMCID:
PMC10283053
AbstractArticlePDF–14M
16.
Aqp4 stop codon readthrough facilitates amyloid-β clearance from the brain
Darshan Sapkota, Colin Florian, Brookelyn M Doherty, Kelli M White, Kate M Reardon, Xia Ge, Joel R Garbow, Carla M Yuede, John R Cirrito, Joseph D Dougherty
Brain. 2022 Sep; 145(9): 2982–2990. Published online 2022 Aug 18. doi: 10.1093/brain/awac199
PMCID:
PMC10233234
AbstractArticlePDF–1.2M
17.
AQP4 Aggravates Cognitive Impairment in Sepsis‐Associated Encephalopathy through Inhibiting Nav1.6‐Mediated Astrocyte Autophagy
Dan‐Dan Zhu, Yue‐Lin Huang, Song‐Yu Guo, Na Li, Xue‐Wei Yang, Ao‐Ran Sui, Qiong Wu, Yue Zhang, Yue Kong, Qi‐Fa Li, Ting Zhang, Wen‐Fei Zheng, Ai‐Ping Li, Jian Yu, Tong‐Hui Ma, Shao Li
Adv Sci (Weinh) 2023 May; 10(14): 2205862. Published online 2023 Mar 15. doi: 10.1002/advs.202205862
Correction in:
Adv Sci (Weinh). 2023 Oct; 10(30): 2306241.
PMCID:
PMC10190498
AbstractArticlePDF–22M
18.
Loss of aquaporin-4 results in glymphatic system dysfunction via brain-wide interstitial fluid stagnation
Ryszard Stefan Gomolka, Lauren M Hablitz, Humberto Mestre, Michael Giannetto, Ting Du, Natalie Linea Hauglund, Lulu Xie, Weiguo Peng, Paula Melero Martinez, Maiken Nedergaard, Yuki Mori
eLife. 2023; 12: e82232. Published online 2023 Feb 9. doi: 10.7554/eLife.82232
PMCID:
PMC9995113
AbstractArticlePDF–6.0M
19.
In utero exposure to maternal anti–aquaporin-4 antibodies alters brain vasculature and neural dynamics in male mouse offspring
Simone Mader, Lior Brimberg, An Vo, Joshua J. Strohl, James M. Crawford, Alexandre Bonnin, Joseph Carrión, Delcora Campbell, Tomás S. Huerta, Andrea La Bella, Roseann Berlin, Stephen L. Dewey, Matthew Hellman, David Eidelberg, Irena Dujmovic, Jelena Drulovic, Jeffrey L. Bennett, Bruce T. Volpe, Patricio T. Huerta, Betty Diamond
Sci Transl Med. Author manuscript; available in PMC 2023 Feb 28.
Published in final edited form as: Sci Transl Med. 2022 Apr 20; 14(641): eabe9726. Published online 2022 Apr 20. doi: 10.1126/scitranslmed.abe9726
PMCID:
PMC9973562
AbstractArticlePDF–2.3M
20.
Aquaporin-4 Expression Switches from White to Gray Matter Regions during Postnatal Development of the Central Nervous System
Francisco Mayo, Lourdes González-Vinceiro, Laura Hiraldo-González, Claudia Calle-Castillejo, Sara Morales-Alvarez, Reposo Ramírez-Lorca, Miriam Echevarría
Int J Mol Sci. 2023 Feb; 24(3): 3048. Published online 2023 Feb 3. doi: 10.3390/ijms24033048
PMCID:
PMC9917791
AbstractArticlePDF–4.4M

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