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Items: 1 to 20 of 129

1.
The CRL3KCTD10 ubiquitin ligase–USP18 axis coordinately regulates cystine uptake and ferroptosis by modulating SLC7A11
Qiyin Zhou, Hongfei Yu, Yongxia Chen, Jiayi Ren, Yan Lu, Yi Sun
Proc Natl Acad Sci U S A. 2024 Jul 9; 121(28): e2320655121. Published online 2024 Jul 3. doi: 10.1073/pnas.2320655121
PMCID:
PMC11252818
AbstractArticlePDF–6.8M
2.
LPCAT2 inhibits colorectal cancer progression via the PRMT1/SLC7A11 axis
Nan Cao, Fangmei Zhang, Jiang Yin, Jianlei Zhang, Xiqing Bian, Guopei Zheng, Nan Li, Ying Lin, Liyun Luo
Oncogene. 2024; 43(22): 1714–1725. Published online 2024 Apr 11. doi: 10.1038/s41388-024-02996-4
PMCID:
PMC11136653
AbstractArticlePDF–6.7M
3.
SLC7A11-ROS/αKG-AMPK axis regulates liver inflammation through mitophagy and impairs liver fibrosis and NASH progression
Tingting Lv, Xiude Fan, Chang He, Suwei Zhu, Xiaofeng Xiong, Wei Yan, Mei Liu, Hongwei Xu, Ruihua Shi, Qin He
Redox Biol. 2024 Jun; 72: 103159. Published online 2024 Apr 16. doi: 10.1016/j.redox.2024.103159
PMCID:
PMC11047786
AbstractArticlePDF–22M
4.
SLC7A11 inhibits ferroptosis and downregulates PD-L1 levels in lung adenocarcinoma
Zhenyao Huang, Xia Chen, Yun Wang, Jiali Yuan, Jing Li, Wenlu Hang, Hao Meng
Front Immunol. 2024; 15: 1372215. Published online 2024 Apr 9. doi: 10.3389/fimmu.2024.1372215
PMCID:
PMC11035808
AbstractArticlePDF–7.0M
5.
The E3 ligase TRIM7 suppresses the tumorigenesis of gastric cancer by targeting SLC7A11
Qishuai Chen, Tongtong Zhang, Runzhi Zeng, Kunmiao Zhang, Bingjun Li, Zhenguo Zhu, Xiaomin Ma, Yun Zhang, Linchuan Li, Jiankang Zhu, Guangyong Zhang
Sci Rep. 2024; 14: 6655. Published online 2024 Mar 20. doi: 10.1038/s41598-024-56746-3
PMCID:
PMC10954695
AbstractArticlePDF–15M
6.
IL-13 facilitates ferroptotic death in asthmatic epithelial cells via SOCS1-mediated ubiquitinated degradation of SLC7A11
Manli Miao, Min Pan, Xu Chen, Jiapan Shen, Ling Zhang, Xiaoxia Feng, Mengting Chen, Guofeng Cui, Huaiyuan Zong, Wen Zhang, Shuang Chang, Fangzhou Xu, Zixi Wang, Dapeng Li, Weiwei Liu, Zhao Ding, Shengquan Zhang, Biao Chen, Xiaojun Zha, Xiaoyun Fan
Redox Biol. 2024 May; 71: 103100. Published online 2024 Mar 8. doi: 10.1016/j.redox.2024.103100
PMCID:
PMC10950698
AbstractArticlePDF–25M
7.
Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma
Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn
Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255
PMCID:
PMC10916866
AbstractArticlePDF–4.7M
8.
Targeting SIRT3 sensitizes glioblastoma to ferroptosis by promoting mitophagy and inhibiting SLC7A11
Xiaohe Li, Wenlong Zhang, Zhengcao Xing, Shuming Hu, Geqiang Zhang, Tiange Wang, Tianshi Wang, Qiuju Fan, Guoqiang Chen, Jinke Cheng, Xianguo Jiang, Rong Cai
Cell Death Dis. 2024 Feb; 15(2): 168. Published online 2024 Feb 23. doi: 10.1038/s41419-024-06558-0
PMCID:
PMC10891132
AbstractArticlePDF–7.1M
9.
SPTBN2 suppresses ferroptosis in NSCLC cells by facilitating SLC7A11 membrane trafficking and localization
Jun Deng, Xu Lin, Jiajia Qin, Qi Li, Yingqiong Zhang, Qingyi Zhang, Cong Ji, Shuying Shen, Yangling Li, Bo Zhang, Nengming Lin
Redox Biol. 2024 Apr; 70: 103039. Published online 2024 Jan 14. doi: 10.1016/j.redox.2024.103039
PMCID:
PMC10825533
AbstractArticlePDF–16M
10.
Expression and Prognostic Significance of Ferroptosis-related Proteins SLC7A11 and GPX4 in Renal Cell Carcinoma
Zongtao Ren, Xiaoyu Zhang, Jingya Han
Protein Pept Lett. 2023 Dec 6; 30(10): 868–876. Published online 2023 Dec 6. doi: 10.2174/0109298665255704230920063254
PMCID:
PMC10788919
AbstractArticlePDF–8.5M
11.
The amino acid transporter SLC7A11 expression in breast cancer
Preyanka Nath, Lutfi H. Alfarsi, Rokaya El-Ansari, Brendah K. Masisi, Busra Erkan, Ali Fakroun, Ian O. Ellis, Emad A. Rakha, Andrew R. Green
Cancer Biol Ther. 2024; 25(1): 2291855. Published online 2023 Dec 10. doi: 10.1080/15384047.2023.2291855
PMCID:
PMC10761065
AbstractArticlePDF–2.1M
12.
KIAA1429 protects hepatocellular carcinoma cells from ferroptotic cell death with a m6A‐dependent posttranscriptional modification of SLC7A11
Houhong Wang, Wenli Chen, Yayun Cui, Huihui Gong, Heng Li
J Cell Mol Med. 2023 Dec; 27(24): 4118–4132. Published online 2023 Oct 13. doi: 10.1111/jcmm.17997
PMCID:
PMC10746954
AbstractArticlePDF–36M
13.
Upregulating miR-181b promotes ferroptosis in osteoarthritic chondrocytes by inhibiting SLC7A11
Dexin Wang, Yu Fang, Liang Lin, Wensuo Long, Lei Wang, Liwei Yu, Huaiming Deng, Dan Wang
BMC Musculoskelet Disord. 2023; 24: 862. Published online 2023 Nov 7. doi: 10.1186/s12891-023-07003-7
PMCID:
PMC10629093
AbstractArticlePDF–9.9M
14.
SLC7A11, a potential immunotherapeutic target in lung adenocarcinoma
Qingqing Shan, Chi Zhang, Yangke Li, Qunying Li, Yifan Zhang, Xue Li, Junqing Shi, Fengying Hu
Sci Rep. 2023; 13: 18302. Published online 2023 Oct 25. doi: 10.1038/s41598-023-45284-z
PMCID:
PMC10600206
AbstractArticlePDF–4.8M
15.
Bulk RNA-seq and scRNA-seq reveal SLC7A11, a key regulatory molecule of ferroptosis, is a prognostic-related biomarker and highly related to the immune system in lung adenocarcinoma
Xiaoyu Wu, Sheng Wang, Kaifang Chen
Medicine (Baltimore) 2023 Sep 15; 102(37): e34876. Published online 2023 Sep 15. doi: 10.1097/MD.0000000000034876
PMCID:
PMC10508384
AbstractArticlePDF–5.3M
16.
Loss of PERK function promotes ferroptosis by downregulating SLC7A11 (System Xc⁻) in colorectal cancer
Krishan Kumar Saini, Priyank Chaturvedi, Abhipsa Sinha, Manish Pratap Singh, Muqtada Ali Khan, Ayushi Verma, Mushtaq Ahmad Nengroo, Saumya Ranjan Satrusal, Sanjeev Meena, Akhilesh Singh, Sameer Srivastava, Jayanta Sarkar, Dipak Datta
Redox Biol. 2023 Sep; 65: 102833. Published online 2023 Jul 28. doi: 10.1016/j.redox.2023.102833
PMCID:
PMC10412847
AbstractArticlePDF–11M
17.
LRP8‐mediated selenocysteine uptake is a targetable vulnerability in MYCN‐amplified neuroblastoma
Hamed Alborzinia, Zhiyi Chen, Umut Yildiz, Florencio Porto Freitas, Felix C E Vogel, Julianna Patricia Varga, Jasmin Batani, Christoph Bartenhagen, Werner Schmitz, Gabriele Büchel, Bernhard Michalke, Jashuo Zheng, Svenja Meierjohann, Enrico Girardi, Elisa Espinet, Andrés F Flórez, Ancely Ferreira dos Santos, Nesrine Aroua, Tasneem Cheytan, Julie Haenlin, Lisa Schlicker, Thamara N Xavier da Silva, Adriana Przybylla, Petra Zeisberger, Giulio Superti‐Furga, Martin Eilers, Marcus Conrad, Marietta Fabiano, Ulrich Schweizer, Matthias Fischer, Almut Schulze, Andreas Trumpp, José Pedro Friedmann Angeli
EMBO Mol Med. 2023 Aug; 15(8): e18014. Published online 2023 Jul 12. doi: 10.15252/emmm.202318014
PMCID:
PMC10405063
AbstractArticlePDF–2.5M
18.
Homocysteine induces ferroptosis in endothelial cells through the systemXc−/GPX4 signaling pathway
Jiahao Shi, Di Chen, Zilin Wang, Shaolin Li, Shuying Zhang
BMC Cardiovasc Disord. 2023; 23: 316. Published online 2023 Jun 24. doi: 10.1186/s12872-023-03342-4
Correction in:
BMC Cardiovasc Disord. 2023; 23: 356.
PMCID:
PMC10290364
AbstractArticlePDF–1.2M
19.
Loss of LncRNA DUXAP8 synergistically enhanced sorafenib induced ferroptosis in hepatocellular carcinoma via SLC7A11 de‐palmitoylation
Zhehao Shi, Zhiming Li, Bin Jin, Wen Ye, Luhui Wang, Sina Zhang, Jiuyi Zheng, Zixia Lin, Bo Chen, Fangting Liu, Baofu Zhang, Xiwei Ding, Zhen Yang, Yunfeng Shan, Zhengping Yu, Yi Wang, Jicai Chen, Qiang Chen, Lewis R. Roberts, Gang Chen
Clin Transl Med. 2023 Jun; 13(6): e1300. Published online 2023 Jun 19. doi: 10.1002/ctm2.1300
PMCID:
PMC10280000
AbstractArticlePDF–4.5M
20.
High co‐expression of SLC7A11 and GPX4 as a predictor of platinum resistance and poor prognosis in patients with epithelial ovarian cancer
Xiaodong Wu, Shizhen Shen, Jiale Qin, Weidong Fei, Fengyun Fan, Jiaxin Gu, Tao Shen, Tao Zhang, Xiaodong Cheng
BJOG. 2022 Nov; 129(Suppl 2): 40–49. Published online 2022 Dec 9. doi: 10.1111/1471-0528.17327
PMCID:
PMC10108211
AbstractArticlePDF–1.2M

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