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Select item 111588831.

Epidermal growth factor receptor intron 1 CA dinucleotide repeat polymorphism and survival of advanced gastric cancer patients treated with cetuximab plus modified FOLFOX6

Sae‐Won Han, Do‐Youn Oh, Seock‐Ah Im, Sook Ryun Park, Keun‐Wook Lee, Hong Suk Song, Nam‐Su Lee, Kyung Hee Lee, In Sil Choi, Moon Hee Lee, Min A Kim, Woo Ho Kim, Yung‐Jue Bang, Tae‐You Kim

Cancer Sci. 2010 Mar; 101(3): 793–799. Published online 2009 Nov 23. doi: 10.1111/j.1349-7006.2009.01447.x

PMCID:: PMC11158883

Abstract Article PDF–174K

Select item 111582092.

Clinical significance of pretreatment serum amphiregulin and transforming growth factor‐α, and an epidermal growth factor receptor somatic mutation in patients with advanced non‐squamous, non‐small cell lung cancer

Katsuhiro Masago, Shiro Fujita, Yukimasa Hatachi, Akiko Fukuhara, Keiichiro Sakuma, Masataka Ichikawa, Yung Haku Kim, Tadashi Mio, Michiaki Mishima

Cancer Sci. 2008 Nov; 99(11): 2295–2301. Published online 2008 Sep 22. doi: 10.1111/j.1349-7006.2008.00931.x

PMCID:: PMC11158209

Abstract Article PDF–175K

Select item 110310643.

TGF-alpha as a candidate tumor antigen for renal cell carcinomas

Sandy Pelletier, Simon Tanguay, Stephen Lee, Lakshman Gunaratnam, Nathalie Arbour, Réjean Lapointe

Cancer Immunol Immunother. 2009 Aug; 58(8): 1207–1218. Published online 2008 Dec 4. doi: 10.1007/s00262-008-0630-2

PMCID:: PMC11031064

Abstract Article PDF–493K

Select item 108446984.

TGFA expression is associated with poor prognosis and promotes the development of cervical cancer

Xiaoxuan Ma, Jingying Zheng, Kang He, Liangjia Wang, Zeyu Wang, Kai Wang, Zunlong Liu, Zhiqiang San, Lijing Zhao, Lisheng Wang

J Cell Mol Med. 2024 Feb; 28(3): e18086. Published online 2023 Dec 28. doi: 10.1111/jcmm.18086

PMCID:: PMC10844698

Abstract Article PDF–20M

Select item 104874845.

EGF, TGF-α and Amphiregulin Differently Regulate Endometrium-Derived Mesenchymal Stromal/Stem Cells

Rimma Sergeevna Kamentseva, Marianna Viktorovna Kharchenko, Gulnara Vladikovna Gabdrahmanova, Michael Alexandrovich Kotov, Vera Vladislavovna Kosheverova, Elena Sergeevna Kornilova

Int J Mol Sci. 2023 Sep; 24(17): 13408. Published online 2023 Aug 29. doi: 10.3390/ijms241713408

PMCID:: PMC10487484

Abstract Article PDF–26M

Select item 87868906.

Genetic markers for non-syndromic orofacial clefts in populations of European ancestry: a meta-analysis

Lara Slavec, Nataša Karas Kuželički, Igor Locatelli, Ksenija Geršak

Sci Rep. 2022; 12: 1214. Published online 2022 Jan 24. doi: 10.1038/s41598-021-02159-5

PMCID:: PMC8786890

Abstract Article PDF–1.9M

Select item 83659337.

Altered proTGFα/cleaved TGFα ratios offer new therapeutic strategies in renal carcinoma

Sara García-Alonso, Inés Romero-Pérez, Lucía Gandullo-Sánchez, Luis Chinchilla, Alberto Ocaña, Juan Carlos Montero, Atanasio Pandiella

J Exp Clin Cancer Res. 2021; 40: 256. Published online 2021 Aug 16. doi: 10.1186/s13046-021-02051-0

PMCID:: PMC8365933

Abstract Article PDF–1.7M

Select item 83122798.

The Aryl Hydrocarbon Receptor–Dependent TGF-α/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis

Ana Cirac, Thanos Tsaktanis, Tobias Beyer, Mathias Linnerbauer, Till Andlauer, Verena Grummel, Lucy Nirschl, Lena Loesslein, Francisco J. Quintana, Bernhard Hemmer, Veit Rothhammer

Neurol Neuroimmunol Neuroinflamm. 2021 Sep; 8(5): e1043. Published online 2021 Jul 23. doi: 10.1212/NXI.0000000000001043

PMCID:: PMC8312279

Abstract Article PDF–771K

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 808677010.

MicroRNA-374b inhibits breast cancer progression through regulating CCND1 and TGFA genes

Yan Liu, Ai Zhang, Ping-Ping Bao, Li Lin, Yina Wang, Haijian Wu, Xiao-Ou Shu, Aiguo Liu, Qiuyin Cai

Carcinogenesis. 2021 Apr; 42(4): 528–536. Published online 2021 Jan 22. doi: 10.1093/carcin/bgab005

PMCID:: PMC8086770

Abstract Article PDF–813K

Select item 793207611.

LncRNA LINC00857 strengthens the malignancy behaviors of pancreatic adenocarcinoma cells by serving as a competing endogenous RNA for miR-340-5p to upregulate TGFA expression

Tingfu Li, Hongbo Zhao, Hua Zhou, Tingting Geng

PLoS One. 2021; 16(3): e0247817. Published online 2021 Mar 4. doi: 10.1371/journal.pone.0247817

PMCID:: PMC7932076

Abstract Article PDF–2.9M

Select item 756842212.

Ovarian cancer cells direct monocyte differentiation through a non-canonical pathway

Kaitlin C. Fogg, Andrew E. Miller, Ying Li, Will Flanigan, Alyssa Walker, Andrea O’Shea, Christina Kendziorski, Pamela K. Kreeger

BMC Cancer. 2020; 20: 1008. Published online 2020 Oct 17. doi: 10.1186/s12885-020-07513-w

PMCID:: PMC7568422

Abstract Article PDF–1.6M

Select item 716998313.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 698120614.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS^G13D

Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch

Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9

PMCID:: PMC6981206

Abstract Article PDF–3.7M

Select item 639806015.

Blockage of TGF-α Induced by Spherical Silica Nanoparticles Inhibits Epithelial-Mesenchymal Transition and Proliferation of Human Lung Epithelial Cells

YiXun Li, Huan Li, Yong Duan, XueMei Cai, DingYun You, Feng Zhou, ChuanQi Yang, XiaoYu Tuo, ZiJie Liu

Biomed Res Int. 2019; 2019: 8231267. Published online 2019 Feb 18. doi: 10.1155/2019/8231267

PMCID:: PMC6398060

Abstract Article PDF–3.8M

Select item 565092116.

EGFR ligands differentially stabilize receptor dimers to specify signaling kinetics

Daniel M. Freed, Nicholas J. Bessman, Anatoly Kiyatkin, Emanuel Salazar-Cavazos, Patrick O. Byrne, Jason O. Moore, Christopher C. Valley, Kathryn M. Ferguson, Daniel J. Leahy, Diane S. Lidke, Mark A. Lemmon

Cell. Author manuscript; available in PMC 2018 Oct 19.

Published in final edited form as: Cell. 2017 Oct 19; 171(3): 683–695.e18. Published online 2017 Oct 5. doi: 10.1016/j.cell.2017.09.017

PMCID:: PMC5650921

Abstract Article PDF–1.6M

Select item 548518117.

A loop of cancer-stroma-cancer interaction promotes peritoneal metastasis of ovarian cancer via TNFα-TGFα-EGFR

T-S Lau, L K-Y Chan, E C-H Wong, C W-C Hui, K Sneddon, T-H Cheung, S-F Yim, J H-S Lee, C S-Y Yeung, T K-H Chung, J Kwong

Oncogene. 2017 Jun 22; 36(25): 3576–3587. Published online 2017 Feb 6. doi: 10.1038/onc.2016.509

PMCID:: PMC5485181

Abstract Article PDF–4.8M

Select item 541915818.

G Protein-Coupled Receptor 30 Expression Is Up-Regulated by EGF and TGFα in Estrogen Receptor α-Positive Cancer Cells

Adele Vivacqua, Rosamaria Lappano, Paola De Marco, Diego Sisci, Saveria Aquila, Francesca De Amicis, Suzanne A. W. Fuqua, Sebastiano Andò, Marcello Maggiolini

Mol Endocrinol. November 1, 2009; 23(11): 1815–1826. doi: 10.1210/me.2009-0120

PMCID:: PMC5419158

Abstract Article

Select item 534237719.

MALAT1 promotes osteosarcoma development by targeting TGFA via MIR376A

Wei Luo, Hongbo He, Wenfeng Xiao, Qing Liu, Zhenhan Deng, Yaojuan Lu, Qian Wang, Qiping Zheng, Yusheng Li

Oncotarget. 2016 Aug 23; 7(34): 54733–54743. Published online 2016 Jul 21. doi: 10.18632/oncotarget.10752

PMCID:: PMC5342377

Abstract Article PDF–6.9M

Select item 504976320.

Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis

Martha C. Castaño-Betancourt, Dan S. Evans, Yolande F. M. Ramos, Cindy G. Boer, Sarah Metrustry, Youfang Liu, Wouter den Hollander, Jeroen van Rooij, Virginia B. Kraus, Michelle S. Yau, Braxton D. Mitchell, Kenneth Muir, Albert Hofman, Michael Doherty, Sally Doherty, Weiya Zhang, Robert Kraaij, Fernando Rivadeneira, Elizabeth Barrett-Connor, Rose A. Maciewicz, Nigel Arden, Rob G. H. H. Nelissen, Margreet Kloppenburg, Joanne M. Jordan, Michael C. Nevitt, Eline P. Slagboom, Deborah J. Hart, Floris Lafeber, Unnur Styrkarsdottir, Eleftheria Zeggini, Evangelos Evangelou, Tim D. Spector, Andre G. Uitterlinden, Nancy E. Lane, Ingrid Meulenbelt, Ana M. Valdes, Joyce B. J. van Meurs

PLoS Genet. 2016 Oct; 12(10): e1006260. Published online 2016 Oct 4. doi: 10.1371/journal.pgen.1006260

PMCID:: PMC5049763

Abstract Article PDF–2.3M

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