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Select item 111695021.

Deletion of Tmem268 in mice suppresses anti-infectious immune responses by downregulating CD11b signaling

Mengyuan Duan, Xuan Zhang, Yaxin Lou, Jinqiu Feng, Pengli Guo, Shufang Ye, Ping Lv, Yingyu Chen

EMBO Rep. 2024 Jun; 25(6): 2550–2570. Published online 2024 May 10. doi: 10.1038/s44319-024-00141-6

PMCID:: PMC11169502

Abstract Article PDF–7.9M

Select item 111658542.

The integrin CD11b inhibits MSU-induced NLRP3 inflammasome activation in macrophages and protects mice against MSU-induced joint inflammation

Driss Ehirchiou, Ilaria Bernabei, Vishnuprabu Durairaj Pandian, Sonia Nasi, Veronique Chobaz, Mariela Castelblanco, Alexander So, Fabio Martinon, Xiaoyun Li, Hans Acha-Orbea, Thomas Hugle, Li Zhang, Nathalie Busso

Arthritis Res Ther. 2024; 26: 119. Published online 2024 Jun 11. doi: 10.1186/s13075-024-03350-5

PMCID:: PMC11165854

Abstract Article PDF–1.6M

Select item 110167583.

A LTB₄/CD11b self-amplifying loop drives pyogranuloma formation in chronic granulomatous disease

Kelsey C. Haist, Sophie L. Gibbings, Jordan Jacobelli, Kara J. Mould, Peter M. Henson, Donna L. Bratton

iScience. 2024 Apr 19; 27(4): 109589. Published online 2024 Mar 27. doi: 10.1016/j.isci.2024.109589

PMCID:: PMC11016758

Abstract Article PDF–5.3M

Select item 109499534.

Phagocytosis via complement receptor 3 enables microbes to evade killing by neutrophils

Asya Smirnov, Kylene P. Daily, Mary C. Gray, Stephanie A. Ragland, Lacie M. Werner, M. Brittany Johnson, Joshua C. Eby, Erik L. Hewlett, Ronald P. Taylor, Alison K. Criss

J Leukoc Biol. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: J Leukoc Biol. 2023 Jul 1; 114(1): 1–20. doi: 10.1093/jleuko/qiad028

PMCID:: PMC10949953

Abstract Article PDF–2.1M

Select item 109176605.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108691396.

Microglia maintain structural integrity during fetal brain morphogenesis

Akindé René Lawrence, Alice Canzi, Cécile Bridlance, Nicolas Olivié, Claire Lansonneur, Clarissa Catale, Lara Pizzamiglio, Benoit Kloeckner, Aymeric Silvin, David A.D. Munro, Aurélien Fortoul, Davide Boido, Feriel Zehani, Hugues Cartonnet, Sarah Viguier, Guillaume Oller, Paola Squarzoni, Adrien Candat, Julie Helft, Cécile Allet, Francoise Watrin, Jean-Bernard Manent, Pierre Paoletti, Denis Thieffry, Laura Cantini, Clare Pridans, Josef Priller, Antoinette Gélot, Paolo Giacobini, Luisa Ciobanu, Florent Ginhoux, Morgane Sonia Thion, Ludmilla Lokmane, Sonia Garel

Cell. 2024 Feb 15; 187(4): 962–980.e19. doi: 10.1016/j.cell.2024.01.012

PMCID:: PMC10869139

Abstract Article

Select item 107908237.

Impact of surface receptors TLR2, CR3, and FcγRIII on Rhodococcus equi phagocytosis and intracellular survival in macrophages

Bibiana Petri da Silveira, Rola Barhoumi, Jocelyne M. Bray, Hannah M. Cole-Pfeiffer, Cory J. Mabry, Robert C. Burghardt, Noah D. Cohen, Angela I. Bordin

Infect Immun. 2024 Jan; 92(1): e00383-23. Published online 2023 Nov 29. doi: 10.1128/iai.00383-23

PMCID:: PMC10790823

Abstract Article PDF–4.6M

Select item 107701128.

CD11b mediates hypertensive cardiac remodeling by regulating macrophage infiltration and polarization

Yun-Long Zhang, Jie Bai, Wei-Jia Yu, Qiu-Yue Lin, Hui-Hua Li

J Adv Res. 2024 Jan; 55: 17–31. Published online 2023 Feb 21. doi: 10.1016/j.jare.2023.02.010

PMCID:: PMC10770112

Abstract Article PDF–10M

Select item 107538539.

Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis

Yifan Wu, Shuqi Du, Lynn H. Bimler, Kelsey E. Mauk, Léa Lortal, Nessim Kichik, James S. Griffiths, Radim Osicka, Lizhen Song, Katherine Polsky, Lydia Kasper, Peter Sebo, Jill Weatherhead, J. Morgan Knight, Farrah Kheradmand, Hui Zheng, Jonathan P. Richardson, Bernhard Hube, Julian R. Naglik, David B. Corry

Cell Rep. Author manuscript; available in PMC 2023 Dec 28.

Published in final edited form as: Cell Rep. 2023 Oct 31; 42(10): 113240. Published online 2023 Oct 17. doi: 10.1016/j.celrep.2023.113240

PMCID:: PMC10753853

Abstract Article PDF–1.6M

Select item 1070318010.

Escherichia coli adhesion protein FimH exacerbates colitis via CD11b⁺CD103^- dendritic cell activation

Wei Zhang, Eun-Koung An, So-Jung Kim, Hae-Bin Park, Peter C. W. Lee, Jun-O Jin

Front Immunol. 2023; 14: 1284770. Published online 2023 Nov 22. doi: 10.3389/fimmu.2023.1284770

PMCID:: PMC10703180

Abstract Article PDF–7.5M

Select item 1070278411.

Ontogenesis of the Mouse Ocular Surface Lymphatic Vascular Network

Mariela Subileau, Daniel Vittet

Invest Ophthalmol Vis Sci. 2023 Dec; 64(15): 7. Published online 2023 Dec 6. doi: 10.1167/iovs.64.15.7

PMCID:: PMC10702784

Abstract Article PDF–12M

Select item 1053794112.

CD11a regulates hematopoietic stem and progenitor cells

Lifei Hou, Koichi Yuki

Front Immunol. 2023; 14: 1219953. Published online 2023 Sep 14. doi: 10.3389/fimmu.2023.1219953

PMCID:: PMC10537941

Abstract Article PDF–1.3M

Select item 1052487913.

The complement-targeted inhibitor mini-FH protects against experimental periodontitis via both C3–dependent and C3–independent mechanisms

Xiaofei Li, Hui Wang, Christoph Q. Schmidt, Viviana P. Ferreira, Despina Yancopoulou, Dimitrios C. Mastellos, John D. Lambris, George Hajishengallis

J Immunol. Author manuscript; available in PMC 2024 Aug 1.

Published in final edited form as: J Immunol. 2023 Aug 1; 211(3): 453–461. doi: 10.4049/jimmunol.2300242

PMCID:: PMC10524879

Abstract Article PDF–1.8M

Select item 1048047714.

Notch and retinoic acid signals regulate macrophage formation from endocardium downstream of Nkx2-5

Norika Liu, Naofumi Kawahira, Yasuhiro Nakashima, Haruko Nakano, Akiyasu Iwase, Yasunobu Uchijima, Mei Wang, Sean M. Wu, Susumu Minamisawa, Hiroki Kurihara, Atsushi Nakano

Nat Commun. 2023; 14: 5398. Published online 2023 Sep 5. doi: 10.1038/s41467-023-41039-6

PMCID:: PMC10480477

Abstract Article PDF–2.4M

Select item 1041552715.

Complement C3 Enhances LPS-Elicited Neuroinflammation and Neurodegeneration Via the Mac1/NOX2 Pathway

Ran Zhou, Shih-Heng Chen, Zhan Zhao, Dezhen Tu, Sheng Song, Yubao Wang, Qingshan Wang, Jing Feng, Jau-Shyong Hong

Mol Neurobiol. 2023; 60(9): 5167–5183. Published online 2023 Jun 3. doi: 10.1007/s12035-023-03393-w

PMCID:: PMC10415527

Abstract Article PDF–1.6M

Select item 1033004616.

Age-dependent differences in efferocytosis determine the outcome of opsonophagocytic protection from invasive pathogens

Gavyn Chern Wei Bee, Kristen L. Lokken-Toyli, Stephen T. Yeung, Lucie Rodriguez, Tonia Zangari, Exene E. Anderson, Sourav Ghosh, Carla V. Rothlin, Petter Brodin, Kamal M. Khanna, Jeffrey N. Weiser

Immunity. Author manuscript; available in PMC 2024 Jun 13.

Published in final edited form as: Immunity. 2023 Jun 13; 56(6): 1255–1268.e5. Published online 2023 Apr 13. doi: 10.1016/j.immuni.2023.03.018

PMCID:: PMC10330046

Abstract Article PDF–1.8M

Select item 1025393517.

CD11b Deficiency Favors Cartilage Calcification via Increased Matrix Vesicles, Apoptosis, and Lysyl Oxidase Activity

Ilaria Bernabei, Uwe Hansen, Driss Ehirchiou, Jürgen Brinckmann, Veronique Chobaz, Nathalie Busso, Sonia Nasi

Int J Mol Sci. 2023 Jun; 24(11): 9776. Published online 2023 Jun 5. doi: 10.3390/ijms24119776

PMCID:: PMC10253935

Abstract Article PDF–4.7M

Select item 1016800818.

Microglial CD11b Knockout Contributes to Axonal Debris Clearance and Axonal Degradation Attenuation via IGF-1 After Acute Optic Nerve Injury

Jiaxing Zhou, Sen Lin, Qiumei Hu, Xue Li, Xi Chen, Linlin Luo, Shiyang Ye, Wei Liu, Jian Ye

Invest Ophthalmol Vis Sci. 2023 May; 64(5): 7. Published online 2023 May 5. doi: 10.1167/iovs.64.5.7

PMCID:: PMC10168008

Abstract Article PDF–2.1M

Select item 1011041819.

Microglia refine developing retinal astrocytic and vascular networks through the complement C3/C3aR axis

Gopalan Gnanaguru, Steven J. Tabor, Gracia M. Bonilla, Ruslan Sadreyev, Kentaro Yuda, Jörg Köhl, Kip M. Connor

Development. 2023 Mar 1; 150(5): dev201047. Published online 2023 Mar 1. doi: 10.1242/dev.201047

PMCID:: PMC10110418

Abstract Article

Select item 1003129820.

MAC-1 marks a quiescent and functionally superior HSC subset during regeneration

Anna Rydström, Els Mansell, Valgardur Sigurdsson, Julia Sjöberg, Shamit Soneji, Kenichi Miharada, Jonas Larsson

Stem Cell Reports. 2023 Mar 14; 18(3): 736–748. Published online 2023 Mar 2. doi: 10.1016/j.stemcr.2023.01.014

PMCID:: PMC10031298

Abstract Article PDF–2.0M

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