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Items: 1 to 20 of 44

1.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
2.
Alternative splicing of HSPA12A pre‐RNA by SRSF11 contributes to metastasis potential of colorectal cancer
Yao‐Jie Pan, Fu‐Chun Huo, Meng‐Jie Kang, Bo‐Wen Liu, Meng‐Di Wu, Dong‐Sheng Pei
Clin Transl Med. 2022 Nov; 12(11): e1113. Published online 2022 Nov 17. doi: 10.1002/ctm2.1113
PMCID:
PMC9670187
AbstractArticlePDF–4.6M
3.
Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis
Xi Ling, Jiayi Lu, Xiaoyun Wang, Lan Liu, Lu Liu, Yadi Wang, Yujun Sun, Chune Ren, Chao Lu, Zhenhai Yu
iScience. 2022 Nov 18; 25(11): 105363. Published online 2022 Oct 14. doi: 10.1016/j.isci.2022.105363
PMCID:
PMC9626688
AbstractArticlePDF–6.0M
4.
The Predictive Value of PAK7 Mutation for Immune Checkpoint Inhibitors Therapy in Non-Small Cell Cancer
Hao Zeng, Fan Tong, Yawen Bin, Ling Peng, Xuan Gao, Xuefeng Xia, Xin Yi, Xiaorong Dong
Front Immunol. 2022; 13: 834142. Published online 2022 Feb 3. doi: 10.3389/fimmu.2022.834142
PMCID:
PMC8886445
AbstractArticlePDF–2.5M
5.
PAK5‐stabilized Smuc confers renal cell carcinoma metastasis
Fu‐Chun Huo, Zhi‐Man Zhu, Qiu‐Ying Du, Dong‐Sheng Pei
Clin Transl Med. 2021 Sep; 11(9): e559. Published online 2021 Sep 16. doi: 10.1002/ctm2.559
PMCID:
PMC8444558
ArticlePDF–1.9M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
P21-activated kinase 5 potentiates the chemoresistant phenotype of liver cancer
Ding-Guo Zhang, Chan-Chan Gong, Xiao-Jin Wu, Xin Ren, Randee S. Sedaka, Wei-Cong Chen, Fu-Chun Huo, Cheng Chen, Wen-Qi Du, Dong-Sheng Pei
Signal Transduct Target Ther. 2021; 6: 47. Published online 2021 Feb 5. doi: 10.1038/s41392-020-00409-y
PMCID:
PMC7862393
ArticlePDF–1.2M
8.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
9.
Bioinformatic analysis of the potential molecular mechanism of PAK7 expression in glioblastoma
Xuefeng Wang, Shuang Liu, Zhengkai Shao, Penghai Zhang
Mol Med Rep. 2020 Aug; 22(2): 1362–1372. Published online 2020 Jun 3. doi: 10.3892/mmr.2020.11206
PMCID:
PMC7339666
AbstractArticlePDF–1.4M
10.
PAK5 facilitates the proliferation, invasion and migration in colorectal cancer cells
Silin Huang, Ying Zhu, Chunfei Wang, Xiaxi Li, Xiaobing Cui, Sufang Tu, Lijuan You, JingWen Fu, Zemin Chen, Wei Hu, Wei Gong
Cancer Med. 2020 Jul; 9(13): 4777–4790. Published online 2020 May 8. doi: 10.1002/cam4.3084
PMCID:
PMC7333859
AbstractArticlePDF–2.2M
11.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
12.
PAK5 promotes the migration and invasion of cervical cancer cells by phosphorylating SATB1
Fu-Chun Huo, Yao-Jie Pan, Tong-Tong Li, Jie Mou, Dong-Sheng Pei
Cell Death Differ. 2019 Jun; 26(6): 994–1006. Published online 2018 Aug 6. doi: 10.1038/s41418-018-0178-4
PMCID:
PMC6748095
AbstractArticlePDF–7.2M
13.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
14.
PAK5 Induces EMT and Promotes Cell Migration and Invasion by Activating the PI3K/AKT Pathway in Ovarian Cancer
Diyou Li, Yinglin Pan, Yating Huang, Ping Zhang, Xuhong Fang
Anal Cell Pathol (Amst) 2018; 2018: 8073124. Published online 2018 Sep 2. doi: 10.1155/2018/8073124
PMCID:
PMC6139229
AbstractArticlePDF–5.1M
15.
MiR-106a-5p inhibits the cell migration and invasion of renal cell carcinoma through targeting PAK5
Yao-Jie Pan, Lu-Lu Wei, Xiao-Jin Wu, Fu-Chun Huo, Jie Mou, Dong-Sheng Pei
Cell Death Dis. 2017 Oct; 8(10): e3155. Published online 2017 Oct 26. doi: 10.1038/cddis.2017.561
PMCID:
PMC5680926
AbstractArticlePDF–4.7M
16.
PAK5-mediated phosphorylation and nuclear translocation of NF-κB-p65 promotes breast cancer cell proliferation in vitro and in vivo
Ying-Chun Zhang, Fu-Chun Huo, Lu-Lu Wei, Chan-Chan Gong, Yao-Jie Pan, Jie Mou, Dong-Sheng Pei
J Exp Clin Cancer Res. 2017; 36: 146. Published online 2017 Oct 17. doi: 10.1186/s13046-017-0610-5
PMCID:
PMC5645986
AbstractArticlePDF–6.9M
17.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
18.
High-level expression of P21-Cdc/Rac-activated kinase 7 is closely related to metastatic potential and poor prognosis of colon carcinoma
Chao Li, Jian Chen, Yupeng Wang, Guohe Song, Chao Xiao, Dongwang Yan, Lin Zhong, Xing Sun, Xiaoliang Wang, Fudong Yu, Yang Yu, Huamei Tang, Zhihai Peng
Oncotarget. 2016 Jul 19; 7(29): 46042–46055. Published online 2016 Jun 14. doi: 10.18632/oncotarget.10017
Correction in:
Oncotarget. 2017 Jul 4; 8(27): 45031.
PMCID:
PMC5216780
AbstractArticlePDF–10M
19.
Mitochondrial protein interaction mapping identifies new regulators of respiratory chain function
Brendan J. Floyd, Emily M. Wilkerson, Mike T. Veling, Catie E. Minogue, Chuanwu Xia, Emily T. Beebe, Russell L. Wrobel, Holly Cho, Laura S. Kremer, Charlotte L. Alston, Katarzyna A. Gromek, Brendan K. Dolan, Arne Ulbrich, Jonathan A. Stefely, Sarah L. Bohl, Kelly M. Werner, Adam Jochem, Michael S. Westphall, Jarred W. Rensvold, Robert W. Taylor, Holger Prokisch, Jung-Ja P. Kim, Joshua J. Coon, David J. Pagliarini
Mol Cell. Author manuscript; available in PMC 2017 Aug 18.
Published in final edited form as: Mol Cell. 2016 Aug 18; 63(4): 621–632. Published online 2016 Aug 4. doi: 10.1016/j.molcel.2016.06.033
PMCID:
PMC4992456
AbstractArticlePDF–1.7M
20.
An inter‐species protein–protein interaction network across vast evolutionary distance
Quan Zhong, Samuel J Pevzner, Tong Hao, Yang Wang, Roberto Mosca, Jörg Menche, Mikko Taipale, Murat Taşan, Changyu Fan, Xinping Yang, Patrick Haley, Ryan R Murray, Flora Mer, Fana Gebreab, Stanley Tam, Andrew MacWilliams, Amélie Dricot, Patrick Reichert, Balaji Santhanam, Lila Ghamsari, Michael A Calderwood, Thomas Rolland, Benoit Charloteaux, Susan Lindquist, Albert‐László Barabási, David E Hill, Patrick Aloy, Michael E Cusick, Yu Xia, Frederick P Roth, Marc Vidal
Mol Syst Biol. 2016 Apr; 12(4): 865. Published online 2016 Apr 23. doi: 10.15252/msb.20156484
PMCID:
PMC4848758
AbstractArticlePDF–2.1M

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