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Select item 111139631.

Directed structural modification of Clostridium perfringens enterotoxin to enhance binding to claudin-5

Jonas Protze, Miriam Eichner, Anna Piontek, Stefan Dinter, Jan Rossa, Kinga Grażyna Blecharz, Peter Vajkoczy, Joerg Piontek, Gerd Krause

Cell Mol Life Sci. 2015 Apr; 72(7): 1417–1432. Published online 2014 Oct 24. doi: 10.1007/s00018-014-1761-6

PMCID:: PMC11113963

Abstract Article PDF–3.4M

Select item 111053302.

Tight junction proteins at the blood–brain barrier: far more than claudin-5

Philipp Berndt, Lars Winkler, Jimmi Cording, Olga Breitkreuz-Korff, André Rex, Sophie Dithmer, Valentina Rausch, Rosel Blasig, Matthias Richter, Anje Sporbert, Hartwig Wolburg, Ingolf E. Blasig, Reiner F. Haseloff

Cell Mol Life Sci. 2019 May; 76(10): 1987–2002. Published online 2019 Feb 7. doi: 10.1007/s00018-019-03030-7

PMCID:: PMC11105330

Abstract Article PDF–2.4M

Select item 110930693.

MiRNA‐224‐5p regulates the defective permeability barrier in sensitive skin by targeting claudin‐5

Li Yang, Wen‐Juan Wu, Le‐Chun Lyu, Ying Tu, Hua Gu, Xiang‐Feng Chen, Yan‐Jie Chai, Mao‐Qiang Man, Li He

Skin Res Technol. 2024 May; 30(5): e13720. Published online 2024 May 14. doi: 10.1111/srt.13720

PMCID:: PMC11093069

Abstract Article PDF–4.3M

Select item 108554094.

Association of Plasma Claudin-5 with Age and Alzheimer Disease

Keisuke Tachibana, Ryuichi Hirayama, Naoyuki Sato, Kotaro Hattori, Takashi Kato, Hiroyuki Takeda, Masuo Kondoh

Int J Mol Sci. 2024 Feb; 25(3): 1419. Published online 2024 Jan 24. doi: 10.3390/ijms25031419

PMCID:: PMC10855409

Abstract Article PDF–1.2M

Select item 102578375.

Downregulation of Claudin5 promotes malignant progression and radioresistance through Beclin1-mediated autophagy in esophageal squamous cell carcinoma

Shan Huang, Jiayi Zhang, Yi Li, Yaqiong Xu, Hui Jia, Lei An, Xiaotan Wang, Yuting Yang

J Transl Med. 2023; 21: 379. Published online 2023 Jun 11. doi: 10.1186/s12967-023-04248-7

PMCID:: PMC10257837

Abstract Article PDF–7.8M

Select item 100448256.

The CLDN5 gene at the blood-brain barrier in health and disease

Yosuke Hashimoto, Chris Greene, Arnold Munnich, Matthew Campbell

Fluids Barriers CNS. 2023; 20: 22. Published online 2023 Mar 28. doi: 10.1186/s12987-023-00424-5

PMCID:: PMC10044825

Abstract Article PDF–6.7M

Select item 100323047.

Inflammation and Blood-Brain Barrier in Depression: Interaction of CLDN5 and IL6 Gene Variants in Stress-Induced Depression

Zsofia Gal, Dora Torok, Xenia Gonda, Nora Eszlari, Ian Muir Anderson, Bill Deakin, Gabriella Juhasz, Gyorgy Bagdy, Peter Petschner

Int J Neuropsychopharmacol. 2023 Mar; 26(3): 189–197. Published online 2022 Dec 6. doi: 10.1093/ijnp/pyac079

PMCID:: PMC10032304

Abstract Article PDF–3.1M

Select item 95865458.

Recurrent de novo mutations in CLDN5 induce an anion-selective blood–brain barrier and alternating hemiplegia

Yosuke Hashimoto, Karine Poirier, Nathalie Boddaert, Laurence Hubert, Melodie Aubart, Anna Kaminska, Marianne Alison, Isabelle Desguerre, Arnold Munnich, Matthew Campbell

Brain. 2022 Oct; 145(10): 3374–3382. Published online 2022 Jun 17. doi: 10.1093/brain/awac215

PMCID:: PMC9586545

Abstract Article PDF–1.0M

Select item 94917269.

SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression

Rina Hashimoto, Junya Takahashi, Keisuke Shirakura, Risa Funatsu, Kaori Kosugi, Sayaka Deguchi, Masaki Yamamoto, Yugo Tsunoda, Maaya Morita, Kosuke Muraoka, Masato Tanaka, Tomoaki Kanbara, Shota Tanaka, Shigeyuki Tamiya, Nagisa Tokunoh, Atsushi Kawai, Masahito Ikawa, Chikako Ono, Keisuke Tachibana, Masuo Kondoh, Masanori Obana, Yoshiharu Matsuura, Akihiro Ohsumi, Takeshi Noda, Takuya Yamamoto, Yasuo Yoshioka, Yu-suke Torisawa, Hiroshi Date, Yasushi Fujio, Miki Nagao, Kazuo Takayama, Yoshiaki Okada

Sci Adv. 2022 Sep; 8(38): eabo6783. Published online 2022 Sep 21. doi: 10.1126/sciadv.abo6783

PMCID:: PMC9491726

Abstract Article PDF–11M

Select item 934765110.

Zonulin and claudin‐5 levels in multisystem inflammatory syndrome and SARS‐CoV‐2 infection in children

Ahmet O Kılıç, Fatih Akın, Abdullah Yazar, Özge Metin Akcan, Cemile Topcu, Orkun Aydın

J Paediatr Child Health. 2022 May 30 : 10.1111/jpc.16033. doi: 10.1111/jpc.16033 [Epub ahead of print]

Correction in:: J Paediatr Child Health. 2023 Jun 28; 59(8): 1010.

PMCID:: PMC9347651

Abstract Article PDF–179K

Select item 906039411.

Hypoxia-induced blood-brain barrier dysfunction is prevented by pericyte-conditioned media via attenuated actomyosin contractility and claudin-5 stabilization

John J. Jamieson, YingYu Lin, Nicholas Malloy, Daniel Soto, Peter C. Searson, Sharon Gerecht

FASEB J. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: FASEB J. 2022 May; 36(5): e22331. doi: 10.1096/fj.202200010RR

PMCID:: PMC9060394

Abstract Article PDF–2.0M

Select item 852601212.

Autophagy alleviates hypoxia-induced blood-brain barrier injury via regulation of CLDN5 (claudin 5)

Zhenguo Yang, Panpan Lin, Bing Chen, Xiaoqi Zhang, Wei Xiao, Shuilong Wu, Chunnian Huang, Du Feng, Wenqing Zhang, Jingjing Zhang

Autophagy. 2021; 17(10): 3048–3067. Published online 2020 Dec 7. doi: 10.1080/15548627.2020.1851897

PMCID:: PMC8526012

Abstract Article PDF–30M

Select item 849765313.

A novel role of claudin-5 in prevention of mitochondrial fission against ischemic/hypoxic stress in cardiomyocytes

Tao Luo, Haiqiong Liu, Baihe Chen, Han Liu, Ahmed Abdel-Latif, Masafumi Kitakaze, Xianbao Wang, Yuanzhou Wu, Dylan Chou, Jin Kyung Kim

Can J Cardiol. Author manuscript; available in PMC 2022 Oct 1.

Published in final edited form as: Can J Cardiol. 2021 Oct; 37(10): 1593–1606. Published online 2021 Apr 8. doi: 10.1016/j.cjca.2021.03.021

PMCID:: PMC8497653

Abstract Article PDF–2.0M

Select item 835887114.

Super‐resolved local recruitment of CLDN5 to filtration slits implicates a direct relationship with podocyte foot process effacement

Florian Tesch, Florian Siegerist, Eleonora Hay, Nadine Artelt, Christoph Daniel, Kerstin Amann, Uwe Zimmermann, Panagiotis Kavvadas, Olaf Grisk, Christos Chadjichristos, Karlhans Endlich, Christos Chatziantoniou, Nicole Endlich

J Cell Mol Med. 2021 Aug; 25(16): 7631–7641. Published online 2021 Jun 22. doi: 10.1111/jcmm.16519

PMCID:: PMC8358871

Abstract Article PDF–2.0M

Select item 832910515.

Brain DNA Methylation Patterns in CLDN5 Associated with Cognitive Decline

Anke Hüls, Chloe Robins, Karen N. Conneely, Rachel Edgar, Philip L. De Jager, David A. Bennett, Aliza P. Wingo, Michael P. Epstein, Thomas S. Wingo

Biol Psychiatry. Author manuscript; available in PMC 2023 Feb 15.

Published in final edited form as: Biol Psychiatry. 2022 Feb 15; 91(4): 389–398. Published online 2021 Feb 3. doi: 10.1016/j.biopsych.2021.01.015

PMCID:: PMC8329105

Abstract Article PDF–674K

Select item 756688116.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z