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Select item 103321211.

Gastric Cancer Growth Modulated by circSNTB2/miR-6938-5p/G0S2 and PDCD4

Baohai Rong, Xiqi Chen, Guangdong Xie, Letian Han, Hanhan Chen, Qingying Sun, Yongkun Zhou

Comb Chem High Throughput Screen. 2023 Jun 12; 26(11): 1990–2002. Published online 2023 Jun 12. doi: 10.2174/1386207326666221108112113

PMCID:: PMC10332121

Abstract Article PDF–6.4M

Select item 97635362.

Loss of G0/G1 switch gene 2 (G0S2) promotes disease progression and drug resistance in chronic myeloid leukaemia (CML) by disrupting glycerophospholipid metabolism

Mayra A. Gonzalez, Idaly M. Olivas, Alfonso E. Bencomo‐Alvarez, Andres J. Rubio, Christian Barreto‐Vargas, Jose L. Lopez, Sara K. Dang, Jonathan P. Solecki, Emily McCall, Gonzalo Astudillo, Vanessa V. Velazquez, Katherine Schenkel, Kelaiah Reffell, Mariah Perkins, Nhu Nguyen, Jehu N. Apaflo, Efren Alvidrez, James E. Young, Joshua J. Lara, Dongqing Yan, Anna Senina, Jonathan Ahmann, Katherine E. Varley, Clinton C. Mason, Christopher A. Eide, Brian J. Druker, Md Nurunnabi, Osvaldo Padilla, Sudip Bajpeyi, Anna M. Eiring

Clin Transl Med. 2022 Dec; 12(12): e1146. Published online 2022 Dec 19. doi: 10.1002/ctm2.1146

PMCID:: PMC9763536

Abstract Article PDF–1.9M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78378524.

Low G0S2 gene expression levels in peripheral blood may be a genetic marker of acute myocardial infarction in patients with stable coronary atherosclerotic disease: A retrospective clinical study

Xue Wang, Heyu Meng, Jianjun Ruan, Weiwei Chen, Fanbo Meng

Medicine (Baltimore) 2021 Jan 22; 100(3): e23468. Published online 2021 Jan 22. doi: 10.1097/MD.0000000000023468

PMCID:: PMC7837852

Abstract Article PDF–689K

Select item 71699835.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 71175456.

Targeted assessment of G0S2 methylation identifies a rapidly recurrent, routinely fatal molecular subtype of adrenocortical carcinoma

Dipika R. Mohan, Antonio Marcondes Lerario, Tobias Else, Bhramar Mukherjee, Madson Q. Almeida, Michelle Vinco, Juilee Rege, Beatriz M. P. Mariani, Maria Claudia N. Zerbini, Berenice B. Mendonca, Ana Claudia Latronico, Suely K. N. Marie, William E. Rainey, Thomas J. Giordano, Maria Candida B. V. Fragoso, Gary D. Hammer

Clin Cancer Res. Author manuscript; available in PMC 2020 Jun 1.

Published in final edited form as: Clin Cancer Res. 2019 Jun 1; 25(11): 3276–3288. Published online 2019 Feb 15. doi: 10.1158/1078-0432.CCR-18-2693

PMCID:: PMC7117545

Abstract Article PDF–2.0M

Select item 70716457.

An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci

Mark W. Logue, Mark W. Miller, Erika J. Wolf, Bertrand Russ Huber, Filomene G. Morrison, Zhenwei Zhou, Yuanchao Zheng, Alicia K. Smith, Nikolaos P. Daskalakis, Andrew Ratanatharathorn, Monica Uddin, Caroline M. Nievergelt, Allison E. Ashley-Koch, Dewleen G. Baker, Jean C. Beckham, Melanie E. Garrett, Marco P. Boks, Elbert Geuze, Gerald A. Grant, Michael A. Hauser, Ronald C. Kessler, Nathan A. Kimbrel, Adam X. Maihofer, Christine E. Marx, Xue-Jun Qin, Victoria B. Risbrough, Bart P. F. Rutten, Murray B. Stein, Robert J. Ursano, Eric Vermetten, Christiaan H. Vinkers, Erin B. Ware, Annjanette Stone, Steven A. Schichman, Regina E. McGlinchey, William P. Milberg, Jasmeet P. Hayes, Mieke Verfaellie, the Traumatic Stress Brain Study Group

Clin Epigenetics. 2020; 12: 46. Published online 2020 Mar 14. doi: 10.1186/s13148-020-0820-0

PMCID:: PMC7071645

Abstract Article PDF–1.5M

Select item 67794498.

A molecular triage process mediated by RING finger protein 126 and BCL2-associated athanogene 6 regulates degradation of G₀/G₁ switch gene 2

Kenta Kamikubo, Hisakazu Kato, Hidetaka Kioka, Satoru Yamazaki, Osamu Tsukamoto, Yuya Nishida, Yoshihiro Asano, Hiromi Imamura, Hiroyuki Kawahara, Yasunori Shintani, Seiji Takashima

J Biol Chem. 2019 Oct 4; 294(40): 14562–14573. Published online 2019 Aug 1. doi: 10.1074/jbc.RA119.008544

PMCID:: PMC6779449

Abstract Article PDF–2.5M

Select item 64639109.

Identification of an intrinsic lysophosphatidic acid acyltransferase activity in the lipolytic inhibitor G₀/G₁ switch gene 2 (G0S2)

Xiaodong Zhang, Xitao Xie, Bradlee L. Heckmann, Alicia M. Saarinen, Haiwei Gu, Rudolf Zechner, Jun Liu

FASEB J. 2019 May; 33(5): 6655–6666. Published online 2019 Feb 25. doi: 10.1096/fj.201802502R

PMCID:: PMC6463910

Abstract Article

Select item 645388610.

A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis

Yilong Zou, Michael J. Palte, Amy A. Deik, Haoxin Li, John K. Eaton, Wenyu Wang, Yuen-Yi Tseng, Rebecca Deasy, Maria Kost-Alimova, Vlado Dančík, Elizaveta S. Leshchiner, Vasanthi S. Viswanathan, Sabina Signoretti, Toni K. Choueiri, Jesse S. Boehm, Bridget K. Wagner, John G. Doench, Clary B. Clish, Paul A. Clemons, Stuart L. Schreiber

Nat Commun. 2019; 10: 1617. Published online 2019 Apr 8. doi: 10.1038/s41467-019-09277-9

PMCID:: PMC6453886

Abstract Article PDF–2.2M

Select item 589094011.

G0S2: a small giant controller of lipolysis and adipose-liver fatty acid flux

Xiaodong Zhang, Bradlee L. Heckmann, Latoya E. Campbell, Jun Liu

Biochim Biophys Acta. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Biochim Biophys Acta. 2017 Oct; 1862(10 Pt B): 1146–1154. Published online 2017 Jun 21. doi: 10.1016/j.bbalip.2017.06.007

PMCID:: PMC5890940

Abstract Article PDF–1.0M

Select item 573141812.

G0S2 represses PI3K/mTOR signaling and increases sensitivity to PI3K/mTOR pathway inhibitors in breast cancer

Christina Y. Yim, Emmanuel Bikorimana, Ema Khan, Joshua M. Warzecha, Leah Shin, Jennifer Rodriguez, Ethan Dmitrovsky, Sarah J. Freemantle, Michael J. Spinella

Cell Cycle. 2017; 16(21): 2146–2155. Published online 2017 Sep 14. doi: 10.1080/15384101.2017.1371884

PMCID:: PMC5731418

Abstract Article PDF–1.2M

Select item 570393013.

Palmitate induces fat accumulation by activating C/EBPβ-mediated G0S2 expression in HepG2 cells

Nai-Qian Zhao, Xiao-Yan Li, Li Wang, Zi-Ling Feng, Xi-Fen Li, Yan-Fang Wen, Jin-Xiang Han

World J Gastroenterol. 2017 Nov 21; 23(43): 7705–7715. Published online 2017 Nov 21. doi: 10.3748/wjg.v23.i43.7705

PMCID:: PMC5703930

Abstract Article PDF–1.2M

Select item 469506014.

Inhibition of adipose triglyceride lipase (ATGL) by the putative tumor suppressor G0S2 or a small molecule inhibitor attenuates the growth of cancer cells

Rachid Zagani, Wissal El-Assaad, Isabelle Gamache, Jose G. Teodoro

Oncotarget. 2015 Sep 29; 6(29): 28282–28295. Published online 2015 Jul 31. doi: 10.18632/oncotarget.5061

PMCID:: PMC4695060

Abstract Article PDF–6.3M

Select item 423961015.

A Peptide Derived from G₀/G₁ Switch Gene 2 Acts as Noncompetitive Inhibitor of Adipose Triglyceride Lipase

Ines K. Cerk, Barbara Salzburger, Andras Boeszoermenyi, Christoph Heier, Christoph Pillip, Matthias Romauch, Martina Schweiger, Irina Cornaciu, Achim Lass, Robert Zimmermann, Rudolf Zechner, Monika Oberer

J Biol Chem. 2014 Nov 21; 289(47): 32559–32570. Published online 2014 Sep 25. doi: 10.1074/jbc.M114.602599

PMCID:: PMC4239610

Abstract Article PDF–1.8M

Select item 402608716.

Mice lacking G0S2 are lean and cold-tolerant

Tian Ma, Alexandra GN Lopez-Aguiar, Aihua Li, Yun Lu, David Sekula, Eugene E Nattie, Sarah Freemantle, Ethan Dmitrovsky

Cancer Biol Ther. 2014 May 1; 15(5): 643–650. Published online 2014 Feb 20. doi: 10.4161/cbt.28251

PMCID:: PMC4026087

Abstract Article PDF–1.6M

Select item 394694117.

G0S2 Inhibits the Proliferation of K562 Cells by Interacting with Nucleolin in the Cytosol

Takeshi Yamada, Chun Shik Park, Ye Shen, Karen R. Rabin, H. Daniel Lacorazza

Leuk Res. Author manuscript; available in PMC 2015 Feb 1.

Published in final edited form as: Leuk Res. 2014 Feb; 38(2): 210–217. Published online 2013 Oct 14. doi: 10.1016/j.leukres.2013.10.006

PMCID:: PMC3946941

Abstract Article PDF–4.0M

Select item 374116018.

The G0/G1 Switch Gene 2 Is an Important Regulator of Hepatic Triglyceride Metabolism

Yinfang Wang, Yahui Zhang, Hang Qian, Juan Lu, Zhifeng Zhang, Xinwen Min, Mingjian Lang, Handong Yang, Nanping Wang, Peng Zhang

PLoS One. 2013; 8(8): e72315. Published online 2013 Aug 12. doi: 10.1371/journal.pone.0072315

PMCID:: PMC3741160

Abstract Article PDF–1.4M

Select item 366119319.

Repression of exogenous gene expression by the retinoic acid target gene G0S2

TIAN MA, JESSICA P. DONG, DAVID J. SEKULA, DENNIS LIANG FEI, WILLIAM W. LAMPH, MICHAEL HENDERSON, YUN LU, STEVEN BLUMEN, SARAH J. FREEMANTLE, ETHAN DMITROVSKY

Int J Oncol. 2013 May; 42(5): 1743–1753. Published online 2013 Mar 28. doi: 10.3892/ijo.2013.1876

PMCID:: PMC3661193

Abstract Article PDF–696K

Select item 355934720.

Modulation of Cytokine Release and Gene Expression by the Immunosuppressive Domain of gp41 of HIV-1

Joachim Denner, Magdalena Eschricht, Michael Lauck, Marwan Semaan, Philipp Schlaermann, Hyunmi Ryu, Levent Akyüz

PLoS One. 2013; 8(1): e55199. Published online 2013 Jan 30. doi: 10.1371/journal.pone.0055199

PMCID:: PMC3559347

Abstract Article PDF–1.0M

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