PMC Links for GEO Profiles (Select 116493906) - PMC

Select item 105306951.

POLD4 Promotes Glioma Cell Proliferation and Suppressive Immune Microenvironment: A Pan-Cancer Analysis Integrated with Experimental Validation

Cheng Jiang, Fei Fan, Weiming Xu, Xiaobing Jiang

Int J Mol Sci. 2023 Sep; 24(18): 13919. Published online 2023 Sep 10. doi: 10.3390/ijms241813919

PMCID:: PMC10530695

Abstract Article PDF–19M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 74432163.

Circular RNA circ_0026359 Enhances Cisplatin Resistance in Gastric Cancer via Targeting miR-1200/POLD4 Pathway

Zongyao Zhang, Xin Yu, Bo Zhou, Jiajia Zhang, Jiacong Chang

Biomed Res Int. 2020; 2020: 5103272. Published online 2020 Aug 13. doi: 10.1155/2020/5103272

PMCID:: PMC7443216

Abstract Article PDF–1.6M

Select item 73060054.

Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer

Shaokun Shu, Hua-Jun Wu, Jennifer Y. Ge, Rhamy Zeid, Isaac S. Harris, Bojana Jovanović, Katherine Murphy, Binbin Wang, Xintao Qiu, Jennifer E. Endress, Jaime Reyes, Klothilda Lim, Alba Font-Tello, Sudeepa Syamala, Tengfei Xiao, Chandra Sekhar Reddy Chilamakuri, Evangelia K. Papachristou, Clive D’Santos, Jayati Anand, Kunihiko Hinohara, Wei Li, Thomas O. McDonald, Adrienne Luoma, Rebecca J. Modiste, Quang-De Nguyen, Brittany Michel, Paloma Cejas, Cigall Kadoch, Jacob D. Jaffe, Kai W. Wucherpfennig, Jun Qi, X. Shirley Liu, Henry Long, Myles Brown, Jason S. Carroll, Joan S. Brugge, James Bradner, Franziska Michor, Kornelia Polyak

Mol Cell. Author manuscript; available in PMC 2021 Jun 18.

Published in final edited form as: Mol Cell. 2020 Jun 18; 78(6): 1096–1113.e8. Published online 2020 May 15. doi: 10.1016/j.molcel.2020.04.027

PMCID:: PMC7306005

Abstract Article PDF–3.2M

Select item 67632215.

Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress

Cecilia Domínguez Conde, Özlem Yüce Petronczki, Safa Baris, Katharina L. Willmann, Enrico Girardi, Elisabeth Salzer, Stefan Weitzer, Rico Chandra Ardy, Ana Krolo, Hanna Ijspeert, Ayca Kiykim, Elif Karakoc-Aydiner, Elisabeth Förster-Waldl, Leo Kager, Winfried F. Pickl, Giulio Superti-Furga, Javier Martínez, Joanna I. Loizou, Ahmet Ozen, Mirjam van der Burg, Kaan Boztug

J Clin Invest. 2019 Oct 1; 129(10): 4194–4206. Published online 2019 Aug 26. doi: 10.1172/JCI128903

PMCID:: PMC6763221

Abstract Article PDF–9.2M

Select item 64240256.

Human DNA polymerase delta is a pentameric holoenzyme with a dimeric p12 subunit

Prashant Khandagale, Doureradjou Peroumal, Kodavati Manohar, Narottam Acharya

Life Sci Alliance. 2019 Apr; 2(2): e201900323. Published online 2019 Mar 18. doi: 10.26508/lsa.201900323

PMCID:: PMC6424025

Abstract Article PDF–2.8M

Select item 55316117.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 39722068.

Proteolysis of the Human DNA Polymerase Delta Smallest Subunit p12 by μ-Calpain in Calcium-Triggered Apoptotic HeLa Cells

Xiaoting Fan, Qian Zhang, Chao You, Yuanxia Qian, Jing Gao, Peng Liu, Huiqing Chen, Huifang Song, Yan Chen, Keping Chen, Yajing Zhou

PLoS One. 2014; 9(4): e93642. Published online 2014 Apr 1. doi: 10.1371/journal.pone.0093642

PMCID:: PMC3972206

Abstract Article PDF–998K

Select item 39257309.

The tail that wags the dog: p12, the smallest subunit of DNA polymerase δ, is degraded by ubiquitin ligases in response to DNA damage and during cell cycle progression

Marietta YWT Lee, Sufang Zhang, Szu Hua Sharon Lin, Xiaoxiao Wang, Zbigniew Darzynkiewicz, Zhongtao Zhang, Ernest YC Lee

Cell Cycle. 2014 Jan 1; 13(1): 23–31. Published online 2013 Dec 3. doi: 10.4161/cc.27407

PMCID:: PMC3925730

Abstract Article PDF–1.3M

Select item 382581710.

Dynamics of Enzymatic Interactions During Short Flap Human Okazaki Fragment Processing by Two forms of Human DNA Polymerase δ

Szu Hua Sharon Lin, Xiaoxiao Wang, Sufang Zhang, Zhongtao Zhang, Ernest Y.C. Lee, Marietta Y.W.T. Lee

DNA Repair (Amst) Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: DNA Repair (Amst). 2013 Nov; 12(11): 10.1016/j.dnarep.2013.08.008. Published online 2013 Sep 10. doi: 10.1016/j.dnarep.2013.08.008

PMCID:: PMC3825817

Abstract Article PDF–6.3M

Select item 379852111.

Degradation of p12 Subunit by CRL4^Cdt2 E3 Ligase Inhibits Fork Progression after DNA Damage

Kenta Terai, Etsuko Shibata, Tarek Abbas, Anindya Dutta

J Biol Chem. 2013 Oct 18; 288(42): 30509–30514. Published online 2013 Sep 10. doi: 10.1074/jbc.C113.505586

PMCID:: PMC3798521

Abstract Article PDF–1.1M

Select item 379525312.

A Novel Function of CRL4^Cdt2: REGULATION OF THE SUBUNIT STRUCTURE OF DNA POLYMERASE δ IN RESPONSE TO DNA DAMAGE AND DURING THE S PHASE

Sufang Zhang, Hong Zhao, Zbiegniew Darzynkiewicz, Pengbo Zhou, Zhongtao Zhang, Ernest Y. C. Lee, Marietta Y. W. T. Lee

J Biol Chem. 2013 Oct 11; 288(41): 29550–29561. Published online 2013 Aug 2. doi: 10.1074/jbc.M113.490466

PMCID:: PMC3795253

Abstract Article PDF–2.0M

Select item 356195013.

Regulation of error-prone translesion synthesis by Spartan/C1orf124

Myoung Shin Kim, Yuka Machida, Ajay A. Vashisht, James A. Wohlschlegel, Yuan-Ping Pang, Yuichi J. Machida

Nucleic Acids Res. 2013 Feb; 41(3): 1661–1668. Published online 2012 Dec 18. doi: 10.1093/nar/gks1267

PMCID:: PMC3561950

Abstract Article PDF–6.1M

Select item 356151714.

Identification of RNF8 as a Ubiquitin Ligase Involved in Targeting the p12 Subunit of DNA Polymerase δ for Degradation in Response to DNA Damage

Sufang Zhang, Yajing Zhou, Ali Sarkeshik, John R. Yates, III, Timothy M. Thomson, Zhongtao Zhang, Ernest Y. C. Lee, Marietta Y. W. T. Lee

J Biol Chem. 2013 Feb 1; 288(5): 2941–2950. Published online 2012 Dec 11. doi: 10.1074/jbc.M112.423392

Correction in:: J Biol Chem. 2014 Jan 17; 289(3): 1212.

PMCID:: PMC3561517

Abstract Article PDF–1.9M

Select item 319070415.

Studies on Human DNA Polymerase ϵ and GINS Complex and Their Role in DNA Replication

Vladimir P. Bermudez, Andrea Farina, Vineetha Raghavan, Inger Tappin, Jerard Hurwitz

J Biol Chem. 2011 Aug 19; 286(33): 28963–28977. Published online 2011 Jun 24. doi: 10.1074/jbc.M111.256289

PMCID:: PMC3190704

Abstract Article PDF–3.1M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 286066017.

The p12 subunit of human polymerase delta modulates the rate and fidelity of DNA synthesis

Xiao Meng, Yajing Zhou, Ernest Y. C. Lee, Marietta Y. W. T. Lee, David N. Frick

Biochemistry. Author manuscript; available in PMC 2011 May 4.

Published in final edited form as: Biochemistry. 2010 May 4; 49(17): 3545–3554. doi: 10.1021/bi100042b

PMCID:: PMC2860660

Abstract Article PDF–1.3M

Select item 253273018.

The Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase δ

Nives Selak, Csanád Z. Bachrati, Igor Shevelev, Tobias Dietschy, Barbara van Loon, Anette Jacob, Ulrich Hübscher, Joerg D. Hoheisel, Ian D. Hickson, Igor Stagljar

Nucleic Acids Res. 2008 Sep; 36(16): 5166–5179. Published online 2008 Aug 5. doi: 10.1093/nar/gkn498

PMCID:: PMC2532730

Abstract Article PDF–8.8M

Select item 51531619.

Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions

Yutaka Suzuki, Riu Yamashita, Matsuyuki Shirota, Yuta Sakakibara, Joe Chiba, Junko Mizushima-Sugano, Kenta Nakai, Sumio Sugano

Genome Res. 2004 Sep; 14(9): 1711–1718. doi: 10.1101/gr.2435604

PMCID:: PMC515316

Abstract Article PDF–181K

Select item 13924120.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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