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Items: 1 to 20 of 107

1.
Transcription factor NKX2–1 drives serine and glycine synthesis addiction in cancer
Elien Heylen, Paulien Verstraete, Linde Van Aerschot, Shauni L. Geeraerts, Tom Venken, Kalina Timcheva, David Nittner, Jelle Verbeeck, Jonathan Royaert, Marion Gijbels, Anne Uyttebroeck, Heidi Segers, Diether Lambrechts, Jan Cools, Kim De Keersmaecker, Kim R. Kampen
Br J Cancer. 2023 May 11; 128(10): 1862–1878. Published online 2023 Mar 17. doi: 10.1038/s41416-023-02216-y
PMCID:
PMC10147615
AbstractArticlePDF–4.2M
2.
Exploring the values, preferences, and information needs of patients with NKX2-1-related disorders: A qualitative study protocol
Carmen Martín-Gómez, Juan Dario Ortigoza-Escobar, Laia Nou-Fontanet, Juan M. Molina-Linde, Anne-Catherine Bachoud-Lévi, Juliane Léger, Juan Antonio Blasco-Amaro, NKX2-1-Related Disorders Guideline Working Group
PLoS One. 2023; 18(2): e0281573. Published online 2023 Feb 9. doi: 10.1371/journal.pone.0281573
PMCID:
PMC9910649
AbstractArticlePDF–508K
3.
Relationship between brain metastasis and thyroid transcription factor 1
Engin Kut, Serkan Menekşe
Sci Rep. 2023; 13: 1945. Published online 2023 Feb 2. doi: 10.1038/s41598-023-29236-1
PMCID:
PMC9895054
AbstractArticlePDF–963K
4.
Transcriptional Circuitry of NKX2-1 and SOX1 Defines an Unrecognized Lineage Subtype of Small-Cell Lung Cancer
Ranran Kong, Ayushi S. Patel, Takashi Sato, Feng Jiang, Seungyeul Yoo, Li Bao, Abhilasha Sinha, Yang Tian, Maya Fridrikh, Shuhui Liu, Jie Feng, Xijing He, Jiantao Jiang, Yuefeng Ma, Karina Grullon, Dawei Yang, Charles A. Powell, Mary Beth Beasley, Jun Zhu, Eric L. Snyder, Shaomin Li, Hideo Watanabe
Am J Respir Crit Care Med. 2022 Dec 15; 206(12): 1480–1494. Published online 2022 Jul 18. doi: 10.1164/rccm.202110-2358OC
PMCID:
PMC9757094
AbstractArticlePDF–3.5M
5.
Optimized thyroid transcription factor-1 core promoter-driven microRNA-7 expression effectively inhibits the growth of human non-small-cell lung cancer cells
Shipeng CHEN, Lian GUAN, Xu ZHAO, Jing YANG, Longqing CHEN, Mengmeng GUO, Juanjuan ZHAO, Chao CHEN, Ya ZHOU, Yong HAN, Lin XU
J Zhejiang Univ Sci B. 2022 Nov 15; 23(11): 915–930. doi: 10.1631/jzus.B2200116
PMCID:
PMC9676096
AbstractArticlePDF–4.0M
6.
The in vivo Interaction Landscape of Histones H3.1 and H3.3
Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins
Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411
PMCID:
PMC9540345
AbstractArticlePDF–3.9M
7.
FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma
Grace Orstad, Gabriela Fort, Timothy J Parnell, Alex Jones, Chris Stubben, Brian Lohman, Katherine L. Gillis, Walter Orellana, Rushmeen Tariq, Olaf Klingbeil, Klaus Kaestner, Christopher R. Vakoc, Benjamin T. Spike, Eric L. Snyder
Dev Cell. Author manuscript; available in PMC 2023 Aug 8.
Published in final edited form as: Dev Cell. 2022 Aug 8; 57(15): 1866–1882.e10. Published online 2022 Jul 13. doi: 10.1016/j.devcel.2022.06.017
PMCID:
PMC9378547
AbstractArticlePDF–3.2M
8.
Altered pituitary morphology as a sign of benign hereditary chorea caused by TITF1/NKX2.1 mutations
Steffi Thust, Liana Veneziano, Michael H. Parkinson, Kailash P. Bhatia, Elide Mantuano, Cristina Gonzalez-Robles, Indran Davagnanam, Paola Giunti
Neurogenetics. 2022; 23(2): 91–102. Published online 2022 Jan 25. doi: 10.1007/s10048-021-00680-3
PMCID:
PMC8960566
AbstractArticlePDF–1.1M
9.
SRGN-Triggered Aggressive and Immunosuppressive Phenotype in a Subset of TTF-1–Negative Lung Adenocarcinomas
Ichidai Tanaka, Delphine Dayde, Mei Chee Tai, Haruki Mori, Luisa M Solis, Satyendra C Tripathi, Johannes F Fahrmann, Nese Unver, Gargy Parhy, Rekha Jain, Edwin R Parra, Yoshiko Murakami, Clemente Aguilar-Bonavides, Barbara Mino, Muge Celiktas, Dilsher Dhillon, Julian Phillip Casabar, Masahiro Nakatochi, Francesco Stingo, Veera Baladandayuthapani, Hong Wang, Hiroyuki Katayama, Jennifer B Dennison, Philip L Lorenzi, Kim-Anh Do, Junya Fujimoto, Carmen Behrens, Edwin J Ostrin, Jaime Rodriguez-Canales, Tetsunari Hase, Takayuki Fukui, Taisuke Kajino, Seiichi Kato, Yasushi Yatabe, Waki Hosoda, Koji Kawaguchi, Kohei Yokoi, Toyofumi F Chen-Yoshikawa, Yoshinori Hasegawa, Adi F Gazdar, Ignacio I Wistuba, Samir Hanash, Ayumu Taguchi
J Natl Cancer Inst. 2022 Feb; 114(2): 290–301. Published online 2021 Sep 15. doi: 10.1093/jnci/djab183
PMCID:
PMC8826620
AbstractArticlePDF–2.5M
10.
NKX2.1 run‐on mutation associated to familial brain–lung–thyroid syndrome
Elena Cavaliere, Anna Jolanda Gortan, Nadia Passon, Dora Fabbro, Dario Marin, Miryam Carecchio, Federica Baldan, Sara Carmela Credendino, Rosa Gallo, Paola Cogo, Giuseppe Damante, Gabriella De Vita
Clin Genet. 2021 Jul; 100(1): 114–116. Published online 2021 Mar 29. doi: 10.1111/cge.13961
PMCID:
PMC8251915
AbstractArticlePDF–642K
11.
TTF-1 and c-MYC-defined Phenotypes of Large Cell Neuroendocrine Carcinoma and Delta-like Protein 3 Expression for Treatment Selection
Aya Miyagawa-Hayashino, Satoru Okada, Naoko Takeda-Miyata, Yasutoshi Takashima, Tadaaki Yamada, Yoshizumi Takemura, Junji Uchino, Masayoshi Inoue, Koichi Takayama, Eiichi Konishi
Appl Immunohistochem Mol Morphol. 2021 Apr; 29(4): 313–320. Published online 2020 Oct 7. doi: 10.1097/PAI.0000000000000875
PMCID:
PMC8132912
AbstractArticlePDF–493K
12.
Deletion of conserved non‐coding sequences downstream from NKX2‐1: A novel disease‐causing mechanism for benign hereditary chorea
Jun Liao, Keith A. Coffman, Joseph Locker, Quasar S. Padiath, Bruce Nmezi, Robyn A. Filipink, Jie Hu, Malini Sathanoori, Suneeta Madan‐Khetarpal, Marianne McGuire, Allison Schreiber, Rocio Moran, Neil Friedman, Lori Hoffner, Aleksandar Rajkovic, Svetlana A. Yatsenko, Urvashi Surti
Mol Genet Genomic Med. 2021 Apr; 9(4): e1647. Published online 2021 Mar 5. doi: 10.1002/mgg3.1647
PMCID:
PMC8123744
AbstractArticlePDF–1.0M
13.
CRISPRi-mediated functional analysis of NKX2-1-binding sites in the lung
William D. Stuart, Iris M. Fink-Baldauf, Koichi Tomoshige, Minzhe Guo, Yutaka Maeda
Commun Biol. 2021; 4: 568. Published online 2021 May 12. doi: 10.1038/s42003-021-02083-4
PMCID:
PMC8115294
AbstractArticlePDF–3.4M
14.
A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition
Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington
Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331
PMCID:
PMC8045932
AbstractArticlePDF–1.9M
15.
The E3 ubiquitin ligase HECW1 targets thyroid transcription factor 1 (TTF1/NKX2.1) for its degradation in the ubiquitin-proteasome system
Jia Liu, Su Dong, Lian Li, Heather Wang, Jing Zhao, Yutong Zhao
Cell Signal. Author manuscript; available in PMC 2020 Nov 2.
Published in final edited form as: Cell Signal. 2019 Jun; 58: 91–98. Published online 2019 Mar 5. doi: 10.1016/j.cellsig.2019.03.005
PMCID:
PMC7604857
AbstractArticlePDF–738K
16.
TTF-1与小细胞肺癌一线化疗敏感性及预后的相关性分析
王 冰睿, 丰 暖, 石 新艳, 綦 琦, 迟 晓蕊, 宋 婷婷, 李 红梅
Zhongguo Fei Ai Za Zhi. 2020 Jul 20; 23(7): 547–553. Chinese. doi: 10.3779/j.issn.1009-3419.2020.101.27
PMCID:
PMC7406437
AbstractArticlePDF–1.2M
17.
Reciprocal expression of trefoil factor‐1 and thyroid transcription factor‐1 in lung adenocarcinomas
Daisuke Matsubara, Taichiro Yoshimoto, Manabu Soda, Yusuke Amano, Atsushi Kihara, Toko Funaki, Takeshi Ito, Yuji Sakuma, Tomoki Shibano, Shunsuke Endo, Koichi Hagiwara, Shumpei Ishikawa, Masashi Fukayama, Yoshinori Murakami, Hiroyuki Mano, Toshiro Niki
Cancer Sci. 2020 Jun; 111(6): 2183–2195. Published online 2020 Apr 30. doi: 10.1111/cas.14403
PMCID:
PMC7293082
AbstractArticlePDF–1.3M
18.
Spectrum of somatic EGFR, KRAS, BRAF, PTEN mutations and TTF-1 expression in Brazilian lung cancer patients
JULIANA G. CARNEIRO, PATRICIA G. COUTO, LUCIANA BASTOS-RODRIGUES, MARIA APARECIDA C. BICALHO, PAULA V. VIDIGAL, ALYNE VILHENA, NILSON F. AMARAL, ALLEN E. BALE, EITAN FRIEDMAN, LUIZ DE MARCO
Genet Res (Camb) 2014; 96: e002. Published online 2014 Mar 5. doi: 10.1017/S0016672314000032
PMCID:
PMC7045132
AbstractArticlePDF–159K
19.
Comparative analysis of TTF‐1 binding DNA regions in small‐cell lung cancer and non‐small‐cell lung cancer
Satoshi Hokari, Yusuke Tamura, Atsushi Kaneda, Akihiro Katsura, Masato Morikawa, Fumihiko Murai, Shogo Ehata, Shuichi Tsutsumi, Yuichi Ishikawa, Hiroyuki Aburatani, Toshiaki Kikuchi, Kohei Miyazono, Daizo Koinuma
Mol Oncol. 2020 Feb; 14(2): 277–293. Published online 2019 Dec 15. doi: 10.1002/1878-0261.12608
PMCID:
PMC6998394
AbstractArticlePDF–4.1M
20.
Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC
Hao Zeng, Johnny Castillo-Cabrera, Mika Manser, Bo Lu, Zinger Yang, Vaik Strande, Damien Begue, Raffaella Zamponi, Shumei Qiu, Frederic Sigoillot, Qiong Wang, Alicia Lindeman, John S Reece-Hoyes, Carsten Russ, Debora Bonenfant, Xiaomo Jiang, Youzhen Wang, Feng Cong
eLife. 2019; 8: e50223. Published online 2019 Nov 19. doi: 10.7554/eLife.50223
PMCID:
PMC6927754
AbstractArticlePDF–5.1M

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