PMC Links for GEO Profiles (Select 117866743) - PMC

Chune Yu, Dan Luo, Jing Yu, Min Zhang, Xiaobo Zheng, Guangchao Xu, Jiaxin Wang, Huiling Wang, Yufei Xu, Ke Jiang, Jie Xu, Xuelei Ma, Jing Jing, Hubing Shi

Oncogene. 2022; 41(2): 191–203. Published online 2021 Oct 30. doi: 10.1038/s41388-021-02077-w

PMCID:: PMC8732282

Abstract Article PDF–6.3M

Select item 76933564.

GRB7 is an oncogenic driver and potential therapeutic target in oesophageal adenocarcinoma

Jovana R Gotovac, David SH Liu, Michael J Yates, Julia V Milne, Arthi A Macpherson, Kaylene J Simpson, Guy D Eslick, Catherine Mitchell, Cuong P Duong, Wayne A Phillips, Nicholas J Clemons

J Pathol. 2020 Nov; 252(3): 317–329. Published online 2020 Sep 15. doi: 10.1002/path.5528

PMCID:: PMC7693356

Abstract Article PDF–4.9M

Select item 76459945.

Upregulated GRB7 promotes proliferation and tumorigenesis of Bladder Cancer via Phospho-AKT Pathway

Yingchun Zheng, Yuanyuan Pei, Le Yang, Zhi Zeng, Jie Wang, Guie Xie, Lan Wang, Jie Yuan

Int J Biol Sci. 2020; 16(16): 3221–3230. Published online 2020 Oct 23. doi: 10.7150/ijbs.49410

PMCID:: PMC7645994

Abstract Article PDF–1.8M

Select item 71699836.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 69812067.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS^G13D

Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch

Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9

PMCID:: PMC6981206

Abstract Article PDF–3.7M

Select item 67426468.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 65625609.

Grb7, a Critical Mediator of EGFR/ErbB Signaling, in Cancer Development and as a Potential Therapeutic Target

Pei-Yu Chu, Yu-Ling Tai, Tang-Long Shen

Cells. 2019 May; 8(5): 435. Published online 2019 May 10. doi: 10.3390/cells8050435

PMCID:: PMC6562560

Abstract Article PDF–789K

Select item 648818310.

Epigenetically altered miR-193a-3p promotes HER2 positive breast cancer aggressiveness by targeting GRB7

Yiyin Tang, Siyuan Yang, Maohua Wang, Dequan Liu, Yang Liu, Ying Zhang, Qian Zhang

Int J Mol Med. 2019 Jun; 43(6): 2352–2360. Published online 2019 Apr 15. doi: 10.3892/ijmm.2019.4167

PMCID:: PMC6488183

Abstract Article PDF–1021K

Select item 600568511.

Grb7 Protein RA Domain Oligomerization

Malika P. Godamudunage, Albert Foster, Darius Warren, Barbara A. Lyons

J Mol Recognit. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: J Mol Recognit. 2017 Aug; 30(8): 10.1002/jmr.2620. Published online 2017 Mar 14. doi: 10.1002/jmr.2620

PMCID:: PMC6005685

Abstract Article PDF–1.1M

Select item 574355812.

Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways

Kangmei Chen, Michelle Xin Liu, Celia Sze-Ling Mak, Mingo Ming-Ho Yung, Thomas Ho-Yin Leung, Dakang Xu, Siew-Fei Ngu, Karen Kar-Loen Chan, Huijuan Yang, Hextan Yuen-Sheung Ngan, David Wai Chan

Theranostics. 2018; 8(2): 423–436. Published online 2018 Jan 1. doi: 10.7150/thno.22377

PMCID:: PMC5743558

Abstract Article PDF–2.5M

Select item 524578013.

Grb7 and Hax1 may colocalize partially to mitochondria in EGF treated SKBR3 cells and their interaction can affect Caspase3 cleavage of Hax1

Lei Qian, Andrew M. Bradford, Peter H. Cooke, Barbara A. Lyons

J Mol Recognit. Author manuscript; available in PMC 2017 Jan 19.

Published in final edited form as: J Mol Recognit. 2016 Jul; 29(7): 318–333. Published online 2016 Feb 12. doi: 10.1002/jmr.2533

PMCID:: PMC5245780

Abstract Article PDF–3.0M

Select item 489171014.

Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7

Menachem J. Gunzburg, Ketav Kulkarni, Gabrielle M. Watson, Nigus D. Ambaye, Mark P. Del Borgo, Rebecca Brandt, Stephanie C. Pero, Patrick Perlmutter, Matthew C. J. Wilce, Jacqueline A. Wilce

Sci Rep. 2016; 6: 27060. Published online 2016 Jun 3. doi: 10.1038/srep27060

PMCID:: PMC4891710

Abstract Article PDF–1.7M

Select item 488219015.

Widespread expansion of protein interaction capabilities by alternative splicing

Xinping Yang, Jasmin Coulombe-Huntington, Shuli Kang, Gloria M. Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun A. Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran-Frigola, Andrew MacWilliams, Samuel J. Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, Song Yi, Maria D. Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong J. Zhou, Kourosh Salehi-Ashtiani, Benoit Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal

Cell. Author manuscript; available in PMC 2017 Feb 11.

Published in final edited form as: Cell. 2016 Feb 11; 164(4): 805–817. doi: 10.1016/j.cell.2016.01.029

PMCID:: PMC4882190

Abstract Article PDF–1.9M

Select item 463766916.

Grb7 gene amplification and protein expression by FISH and IHC in ovarian cancer

Manman Zeng, Zhu Yang, Xiaoyu Hu, Yi Liu, Xiaotao Yang, Hailong Ran, Yanan Li, Xu Li, Qiubo Yu

Int J Clin Exp Pathol. 2015; 8(9): 11296–11304. Published online 2015 Sep 1.

PMCID:: PMC4637669

Abstract Article PDF–886K

Select item 438092817.

Phospho-tyrosine dependent protein–protein interaction network

Arndt Grossmann, Nouhad Benlasfer, Petra Birth, Anna Hegele, Franziska Wachsmuth, Luise Apelt, Ulrich Stelzl

Mol Syst Biol. 2015 Mar; 11(3): 0794. Published online 2015 Mar 26. doi: 10.15252/msb.20145968

PMCID:: PMC4380928

Abstract Article PDF–1.9M

Select item 426658818.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 413655219.

Grb7 binds to Hax-1 and undergoes an intramolecular domain association that offers a model for Grb7 regulation

Sharareh Siamakpour-Reihani, Tabitha A. Peterson, Andrew M. Bradford, Haroula J. Argiros, Laura Lowell Haas, Siamee N. Lor, Zachary M. Haulsee, Anne M. Spuches, Dennis L. Johnson, Larry R. Rohrschneider, Charles Brad Shuster, Barbara A. Lyons

J Mol Recognit. Author manuscript; available in PMC 2014 Aug 18.

Published in final edited form as: J Mol Recognit. 2011 Mar-Apr; 24(2): 314–321. doi: 10.1002/jmr.1062

PMCID:: PMC4136552

Abstract Article PDF–520K

Select item 409656720.

Grb7 and Filamin-a associate and are colocalized to cell membrane ruffles upon EGF stimulation

Prakash Paudyal, Sanjay Shrestha, Thushara Madanayake, Charles B. Shuster, Larry R. Rohrschneider, Aaron Rowland, Barbara A. Lyons

J Mol Recognit. Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: J Mol Recognit. 2013 Nov; 26(11): 532–541. doi: 10.1002/jmr.2297

PMCID:: PMC4096567

Abstract Article PDF–2.2M

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