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Select item 101021261.

High ploidy large cytoplasmic megakaryocytes are hematopoietic stem cells regulators and essential for platelet production

Shen Y. Heazlewood, Tanveer Ahmad, Benjamin Cao, Huimin Cao, Melanie Domingues, Xuan Sun, Chad K. Heazlewood, Songhui Li, Brenda Williams, Madeline Fulton, Jacinta F. White, Tom Nebl, Christian M. Nefzger, Jose M. Polo, Benjamin T. Kile, Felix Kraus, Michael T. Ryan, Yu B. Sun, Peter F. M. Choong, Sarah L. Ellis, Minna-Liisa Anko, Susan K. Nilsson

Nat Commun. 2023; 14: 2099. Published online 2023 Apr 13. doi: 10.1038/s41467-023-37780-7

PMCID:: PMC10102126

Abstract Article PDF–4.4M

Select item 96038602.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 93135453.

Hepatocyte Deletion of IGF2 Prevents DNA Damage and Tumor Formation in Hepatocellular Carcinoma

Deepak Kumar, Manasi Das, Alexis Oberg, Debashis Sahoo, Panyisha Wu, Consuelo Sauceda, Lily Jih, Lesley G. Ellies, Magda T. Langiewicz, Supriya Sen, Nicholas J. G. Webster

Adv Sci (Weinh) 2022 Jul; 9(21): 2105120. Published online 2022 May 26. doi: 10.1002/advs.202105120

PMCID:: PMC9313545

Abstract Article PDF–7.7M

Select item 92260754.

hnRNPH1 recruits PTBP2 and SRSF3 to modulate alternative splicing in germ cells

Shenglei Feng, Jinmei Li, Hui Wen, Kuan Liu, Yiqian Gui, Yujiao Wen, Xiaoli Wang, Shuiqiao Yuan

Nat Commun. 2022; 13: 3588. Published online 2022 Jun 23. doi: 10.1038/s41467-022-31364-7

PMCID:: PMC9226075

Abstract Article PDF–9.8M

Select item 89002705.

The RNA-binding protein SRSF3 has an essential role in megakaryocyte maturation and platelet production

Shen Y. Heazlewood, Tanveer Ahmad, Monika Mohenska, Belinda B. Guo, Pradnya Gangatirkar, Emma C. Josefsson, Sarah L. Ellis, Madara Ratnadiwakara, Huimin Cao, Benjamin Cao, Chad K. Heazlewood, Brenda Williams, Madeline Fulton, Jacinta F. White, Mirana Ramialison, Susan K. Nilsson, Minna-Liisa Änkö

Blood. 2022 Mar 3; 139(9): 1359–1373. doi: 10.1182/blood.2021013826

PMCID:: PMC8900270

Abstract Article

Select item 87442576.

The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins

Mickaële Hémono, Alexandre Haller, Johana Chicher, Anne-Marie Duchêne, Richard Patryk Ngondo

BMC Biol. 2022; 20: 13. Published online 2022 Jan 10. doi: 10.1186/s12915-021-01213-y

PMCID:: PMC8744257

Abstract Article PDF–6.0M

Select item 85915417.

Regulated splicing of large exons is linked to phase‐separation of vertebrate transcription factors

Toshihiko Kawachi, Akio Masuda, Yoshihiro Yamashita, Jun‐ichi Takeda, Bisei Ohkawara, Mikako Ito, Kinji Ohno

EMBO J. 2021 Nov 15; 40(22): e107485. Published online 2021 Oct 4. doi: 10.15252/embj.2020107485

PMCID:: PMC8591541

Abstract Article PDF–5.9M

Select item 83294578.

Long Non-coding RNA T-uc.189 Modulates Neural Progenitor Cell Fate by Regulating Srsf3 During Mouse Cerebral Cortex Development

Meng Zhang, Junjie Zhou, Li Jiao, Longjiang Xu, Lin Hou, Bin Yin, Boqin Qiang, Shuaiyao Lu, Pengcheng Shu, Xiaozhong Peng

Front Neurosci. 2021; 15: 709684. Published online 2021 Jul 20. doi: 10.3389/fnins.2021.709684

PMCID:: PMC8329457

Abstract Article PDF–10M

Select item 83138639.

Srsf3 mediates alternative RNA splicing downstream of PDGFRα signaling in the facial mesenchyme

Brenna J. C. Dennison, Eric D. Larson, Rui Fu, Julia Mo, Katherine A. Fantauzzo

Development. 2021 Jul 15; 148(14): dev199448. Published online 2021 Jul 13. doi: 10.1242/dev.199448

PMCID:: PMC8313863

Abstract Article

Select item 831323910.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 826661711.

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins

Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer

Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490

PMCID:: PMC8266617

Abstract Article PDF–4.0M

Select item 794836112.

SRSF3 and SRSF7 modulate 3′UTR length through suppression or activation of proximal polyadenylation sites and regulation of CFIm levels

Oliver Daniel Schwich, Nicole Blümel, Mario Keller, Marius Wegener, Samarth Thonta Setty, Melinda Elaine Brunstein, Ina Poser, Igor Ruiz De Los Mozos, Beatrix Suess, Christian Münch, François McNicoll, Kathi Zarnack, Michaela Müller-McNicoll

Genome Biol. 2021; 22: 82. Published online 2021 Mar 11. doi: 10.1186/s13059-021-02298-y

PMCID:: PMC7948361

Abstract Article PDF–5.8M

Select item 793877013.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 729503314.

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant

Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely

Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089

PMCID:: PMC7295033

Abstract Article PDF–2.7M

Select item 724432115.

Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression

Stefan Meinke, Gesine Goldammer, A Ioana Weber, Victor Tarabykin, Alexander Neumann, Marco Preussner, Florian Heyd

eLife. 2020; 9: e56075. Published online 2020 Apr 27. doi: 10.7554/eLife.56075

PMCID:: PMC7244321

Abstract Article PDF–694K

Select item 676324716.

Degradation of splicing factor SRSF3 contributes to progressive liver disease

Deepak Kumar, Manasi Das, Consuelo Sauceda, Lesley G. Ellies, Karina Kuo, Purva Parwal, Mehak Kaur, Lily Jih, Gautam K. Bandyopadhyay, Douglas Burton, Rohit Loomba, Olivia Osborn, Nicholas J.G. Webster

J Clin Invest. 2019 Oct 1; 129(10): 4477–4491. Published online 2019 Sep 16. doi: 10.1172/JCI127374

PMCID:: PMC6763247

Abstract Article PDF–14M

Select item 661593117.

Loss of SRSF3 in Cardiomyocytes Leads to Decapping of Contraction-Related mRNAs and Severe Systolic Dysfunction

Paula Ortiz-Sánchez, María Villalba-Orero, Marina M. López-Olañeta, Javier Larrasa-Alonso, Fátima Sánchez-Cabo, Carlos Martí-Gómez, Emilio Camafeita, Jesús M. Gómez-Salinero, Laura Ramos-Hernández, Peter J. Nielsen, Jesús Vázquez, Michaela Müller-McNicoll, Pablo García-Pavía, Enrique Lara-Pezzi

Circ Res. 2019 Jul 5; 125(2): 170–183. Published online 2019 May 30. doi: 10.1161/CIRCRESAHA.118.314515

PMCID:: PMC6615931

Abstract Article PDF–5.1M

Select item 642810818.

Alternative polyadenylation dependent function of splicing factor SRSF3 contributes to cellular senescence

Ting Shen, Huan Li, Yifang Song, Li Li, Jinzhong Lin, Gang Wei, Ting Ni

Aging (Albany NY) 2019 Mar 15; 11(5): 1356–1388. Published online 2019 Mar 4. doi: 10.18632/aging.101836

PMCID:: PMC6428108

Abstract Article PDF–5.7M

Select item 629804019.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 624418320.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

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