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Select item 111315171.

Functions and pathologies of BiP and its interaction partners

J. Dudek, J. Benedix, S. Cappel, M. Greiner, C. Jalal, L. Müller, R. Zimmermann

Cell Mol Life Sci. 2009 May; 66(9): 1556–1569. Published online 2009 Jan 21. doi: 10.1007/s00018-009-8745-y

PMCID:: PMC11131517

Abstract Article PDF–2.1M

Select item 111131792.

ARTC1-mediated ADP-ribosylation of GRP78/BiP: a new player in endoplasmic-reticulum stress responses

Gaia Fabrizio, Simone Di Paola, Annalisa Stilla, Monica Giannotta, Carmen Ruggiero, Stephan Menzel, Friedrich Koch-Nolte, Michele Sallese, Maria Di Girolamo

Cell Mol Life Sci. 2015 Mar; 72(6): 1209–1225. Published online 2014 Oct 8. doi: 10.1007/s00018-014-1745-6

PMCID:: PMC11113179

Abstract Article PDF–1.7M

Select item 110741563.

The interaction of GRP78 and Zika virus E and NS1 proteins occurs in a chaperone-client manner

Wannapa Sornjai, Ploenphit Promma, Suphansa Priewkhiew, Suwipa Ramphan, Janejira Jaratsittisin, Pailin Jinagool, Nitwara Wikan, Michael Greenwood, David Murphy, Duncan R. Smith

Sci Rep. 2024; 14: 10407. Published online 2024 May 6. doi: 10.1038/s41598-024-61195-z

PMCID:: PMC11074156

Abstract Article PDF–3.5M

Select item 110725714.

GRP78 facilitates M2 macrophage polarization and tumour progression

Heng Zhang, Shao-Qiang Wang, Lin Hang, Chun-Fang Zhang, Li Wang, Chao-Jun Duan, Yuan-Da Cheng, Dong-Kai Wu, Ri Chen

Cell Mol Life Sci. 2021 Dec; 78(23): 7709–7732. Published online 2021 Oct 28. doi: 10.1007/s00018-021-03997-2

PMCID:: PMC11072571

Abstract Article PDF–14M

Select item 110290675.

Expression of ERp5 and GRP78 on the membrane of chronic lymphocytic leukemia cells: association with soluble MICA shedding

Leticia Huergo-Zapico, Ana P. Gonzalez-Rodriguez, Juan Contesti, Esther Gonzalez, Alejandro López-Soto, Azahara Fernandez-Guizan, Andrea Acebes-Huerta, Juan R. de los Toyos, Carlos Lopez-Larrea, Veronika Groh, Thomas Spies, Segundo Gonzalez

Cancer Immunol Immunother. 2012 Aug; 61(8): 1201–1210. Published online 2012 Jan 4. doi: 10.1007/s00262-011-1195-z

PMCID:: PMC11029067

Abstract Article PDF–755K

Select item 107989336.

lncRNA HOTAIRM1 Activated by HOXA4 Drives HUVEC Proliferation Through Direct Interaction with Protein Partner HSPA5

Yu Zhou, Qiang Wu, Xiangshu Long, Youfu He, Jing Huang

Inflammation. 2024; 47(1): 421–437. Published online 2023 Oct 29. doi: 10.1007/s10753-023-01919-x

PMCID:: PMC10798933

Abstract Article PDF–6.0M

Select item 107649587.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 106308858.

NRF3 suppresses squamous carcinogenesis, involving the unfolded protein response regulator HSPA5

Selina Gurri, Beat Siegenthaler, Michael Cangkrama, Gaetana Restivo, Marcel Huber, James Saliba, Reinhard Dummer, Volker Blank, Daniel Hohl, Sabine Werner

EMBO Mol Med. 2023 Nov; 15(11): e17761. Published online 2023 Oct 9. doi: 10.15252/emmm.202317761

PMCID:: PMC10630885

Abstract Article PDF–5.3M

Select item 106176739.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 1059101210.

Mechanistic characterization of disulfide bond reduction of an ERAD substrate mediated by cooperation between ERdj5 and BiP

Xiaohan Cai, Shogo Ito, Kentaro Noi, Michio Inoue, Ryo Ushioda, Yukinari Kato, Kazuhiro Nagata, Kenji Inaba

J Biol Chem. 2023 Nov; 299(11): 105274. Published online 2023 Sep 21. doi: 10.1016/j.jbc.2023.105274

PMCID:: PMC10591012

Abstract Article PDF–3.9M

Select item 1058822411.

Research progress on the GRP78 gene in the diagnosis, treatment and immunity of cervical cancer

Yingying Bai, Wenhua Wang, Yuemei Cheng, Yongxiu Yang

Eur J Med Res. 2023; 28: 447. Published online 2023 Oct 20. doi: 10.1186/s40001-023-01241-0

PMCID:: PMC10588224

Abstract Article PDF–1.4M

Select item 1058574312.

PLXNC1 interference alleviates the inflammatory injury, apoptosis and extracellular matrix degradation of IL-1β-exposed chondrocytes via suppressing GRP78 expression

Nan Meng, Lingwei Mao, Qinyi Jiang, Jishan Yuan, Linjuan Liu, Lei Wang

J Orthop Surg Res. 2023; 18: 784. Published online 2023 Oct 18. doi: 10.1186/s13018-023-04207-4

PMCID:: PMC10585743

Abstract Article PDF–5.6M

Select item 1049539613.

EP300 promotes ferroptosis via HSPA5 acetylation in pancreatic cancer

Yuan Wang, Yang Liu, Cong Wang, Rui Kang, Daolin Tang, Jiao Liu

Sci Rep. 2023; 13: 15004. Published online 2023 Sep 11. doi: 10.1038/s41598-023-42136-8

PMCID:: PMC10495396

Abstract Article PDF–1.7M

Select item 1046443614.

Unveiling the dark side of glucose-regulated protein 78 (GRP78) in cancers and other human pathology: a systematic review

Amos Olalekan Akinyemi, Kendall Elizabeth Simpson, Sunday Faith Oyelere, Maria Nur, Chrispus Mutuku Ngule, Bolaji Charles Dayo Owoyemi, Vivian Adiila Ayarick, Felix Femi Oyelami, Oluwafunminiyi Obaleye, Dave-Preston Esoe, Xiaoqi Liu, Zhiguo Li

Mol Med. 2023; 29: 112. Published online 2023 Aug 21. doi: 10.1186/s10020-023-00706-6

PMCID:: PMC10464436

Abstract Article PDF–4.1M

Select item 1035821615.

Insulin‐like growth factor binding protein‐2 and glucose‐regulated protein 78 kDa: Potential biomarkers affect prognosis in IDH‐wildtype glioblastoma patients

Abigail J. Harland, Claire M. Perks, Paul White, Kathreena M. Kurian, Hannah R. Barber

Cancer Med. 2023 Jul; 12(13): 14426–14439. Published online 2023 May 22. doi: 10.1002/cam4.6071

PMCID:: PMC10358216

Abstract Article PDF–6.9M

Select item 1030836516.

A mitochondrial SCF‐FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease

Yu Cao, Jing Zheng, Huayun Wan, Yuqiu Sun, Song Fu, Shanshan Liu, Baiyu He, Gaihong Cai, Yang Cao, Huanwei Huang, Qi Li, Yan Ma, She Chen, Fengchao Wang, Hui Jiang

EMBO J. 2023 Jul; 42(13): e113033. Published online 2023 Mar 10. doi: 10.15252/embj.2022113033

PMCID:: PMC10308365

Abstract Article PDF–5.2M

Select item 1029445117.

Disturbance of neuron–microglia crosstalk mediated by GRP78 in Neuropsychiatric systemic lupus erythematosus mice

Jingyi Xu, Chunshu Yang, Siyuan Zeng, Xuejiao Wang, Pingting Yang, Ling Qin

J Neuroinflammation. 2023; 20: 150. Published online 2023 Jun 26. doi: 10.1186/s12974-023-02832-8

PMCID:: PMC10294451

Abstract Article PDF–7.5M

Select item 1026697118.

Identification of heat shock protein family A member 5 (HSPA5) targets involved in nonalcoholic fatty liver disease

Aliya Rehati, Buzukela Abuduaini, Zhao Liang, Dong Chen, Fangping He

Genes Immun. 2023; 24(3): 124–129. Published online 2023 May 8. doi: 10.1038/s41435-023-00205-y

PMCID:: PMC10266971

Abstract Article PDF–1.7M

Select item 1026281119.

TRIM7/RNF90 promotes autophagy via regulation of ATG7 ubiquitination during L. monocytogenes infection

Jie Wang, Xiao Qin, Yulu Huang, Qunmei Zhang, Jinyong Pei, Yi Wang, Idan Goren, Shujun Ma, Zhishan Song, Yanzi Liu, Hongxia Xing, Hui Wang, Bo Yang

Autophagy. 2023; 19(6): 1844–1862. Published online 2023 Jan 1. doi: 10.1080/15548627.2022.2162706

PMCID:: PMC10262811

Abstract Article PDF–7.7M

Select item 1023742220.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233