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Items: 1 to 20 of 24

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Cathepsin H deficiency decreases hypoxia-ischemia-induced hippocampal atrophy in neonatal mice through attenuated TLR3/IFN-β signaling
Junjun Ni, Juan Zhao, Xinwen Zhang, Thomas Reinheckel, Vito Turk, Hiroshi Nakanishi
J Neuroinflammation. 2021; 18: 176. Published online 2021 Aug 10. doi: 10.1186/s12974-021-02227-7
PMCID:
PMC8353845
AbstractArticlePDF–3.3M
3.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
4.
STAT3 and STAT6 signaling pathways synergize to promote cathepsin secretion from macrophages via IRE1α activation
Dongyao Yan, Hao-Wei Wang, Robert L. Bowman, Johanna A. Joyce
Cell Rep. Author manuscript; available in PMC 2017 Aug 16.
Published in final edited form as: Cell Rep. 2016 Sep 13; 16(11): 2914–2927. doi: 10.1016/j.celrep.2016.08.035
PMCID:
PMC5559199
AbstractArticlePDF–1.0M
5.
Sensing Cytosolic RpsL by Macrophages Induces Lysosomal Cell Death and Termination of Bacterial Infection
Wenhan Zhu, Lili Tao, Marsha L. Quick, Johanna A. Joyce, Jie-Ming Qu, Zhao-Qing Luo
PLoS Pathog. 2015 Mar; 11(3): e1004704. Published online 2015 Mar 4. doi: 10.1371/journal.ppat.1004704
PMCID:
PMC4349785
AbstractArticlePDF–1.1M
6.
CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients
Tina Fløyel, Caroline Brorsson, Lotte B. Nielsen, Michela Miani, Claus Heiner Bang-Berthelsen, Martin Friedrichsen, Anne Julie Overgaard, Lukas A. Berchtold, Anna Wiberg, Pernille Poulsen, Lars Hansen, Silke Rosinger, Bernhard O. Boehm, Ramesh Ram, Quang Nguyen, Munish Mehta, Grant Morahan, Patrick Concannon, Regine Bergholdt, Jens H. Nielsen, Thomas Reinheckel, Matthias von Herrath, Allan Vaag, Decio Laks Eizirik, Henrik B. Mortensen, Joachim Størling, Flemming Pociot
Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28): 10305–10310. Published online 2014 Jun 30. doi: 10.1073/pnas.1402571111
PMCID:
PMC4104872
AbstractArticlePDF–1.0M
7.
Analysis of a lung defect in autophagy-deficient mouse strains
Heesun Cheong, Junmin Wu, Linda K Gonzales, Susan H Guttentag, Craig B Thompson, Tullia Lindsten
Autophagy. 2014 Jan 1; 10(1): 45–56. Published online 2013 Nov 11. doi: 10.4161/auto.26505
PMCID:
PMC4028323
AbstractArticlePDF–2.9M
8.
Alveolar progenitor and stem cells in lung development, renewal and cancer
Tushar J. Desai, Douglas G. Brownfield, Mark A. Krasnow
Nature. Author manuscript; available in PMC 2014 Sep 13.
Published in final edited form as: Nature. 2014 Mar 13; 507(7491): 190–194. Published online 2014 Feb 5. doi: 10.1038/nature12930
PMCID:
PMC4013278
AbstractArticlePDF–1.3M
9.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
10.
Lung epithelial branching program antagonizes alveolar differentiation
Daniel R. Chang, Denise Martinez Alanis, Rachel K. Miller, Hong Ji, Haruhiko Akiyama, Pierre D. McCrea, Jichao Chen
Proc Natl Acad Sci U S A. 2013 Nov 5; 110(45): 18042–18051. Published online 2013 Sep 20. doi: 10.1073/pnas.1311760110
PMCID:
PMC3831485
AbstractArticlePDF–2.2M
11.
Mutations in LRPAP1 Are Associated with Severe Myopia in Humans
Mohammed A. Aldahmesh, Arif O. Khan, Hisham Alkuraya, Nouran Adly, Shamsa Anazi, Ahmed A. Al-Saleh, Jawahir Y. Mohamed, Hadia Hijazi, Sarita Prabakaran, Marlene Tacke, Abdullah Al-Khrashi, Mais Hashem, Thomas Reinheckel, Abdullah Assiri, Fowzan S. Alkuraya
Am J Hum Genet. 2013 Aug 8; 93(2): 313–320. doi: 10.1016/j.ajhg.2013.06.002
PMCID:
PMC3738831
AbstractArticlePDF–1.6M
12.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
13.
Cathepsin H Functions as an Aminopeptidase in Secretory Vesicles for Production of Enkephalin and Galanin Peptide Neurotransmitters
W. Douglas Lu, Lydiane Funkelstein, Thomas Toneff, Thomas Reinheckel, Christoph Peters, Vivian Hook
J Neurochem. Author manuscript; available in PMC 2013 Aug 1.
Published in final edited form as: J Neurochem. 2012 Aug; 122(3): 512–522. Published online 2012 Jun 21. doi: 10.1111/j.1471-4159.2012.07788.x
PMCID:
PMC3417130
AbstractArticlePDF–618K
14.
Gene Targeting of the Cysteine Peptidase Cathepsin H Impairs Lung Surfactant in Mice
Frank Bühling, Martin Kouadio, Caroline E. Chwieralski, Ursula Kern, Jens M. Hohlfeld, Nicole Klemm, Nicole Friedrichs, Wera Roth, Jan M. Deussing, Christoph Peters, Thomas Reinheckel
PLoS One. 2011; 6(10): e26247. Published online 2011 Oct 12. doi: 10.1371/journal.pone.0026247
PMCID:
PMC3192174
AbstractArticlePDF–936K
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
Deletion of cathepsin H perturbs angiogenic switching, vascularization and growth of tumors in a mouse model of pancreatic islet cell cancer
Vasilena Gocheva, Xiaoping Chen, Christoph Peters, Thomas Reinheckel, Johanna A. Joyce
Biol Chem. Author manuscript; available in PMC 2011 Aug 1.
Published in final edited form as: Biol Chem. 2010 Aug; 391(8): 937–945. doi: 10.1515/BC.2010.080
PMCID:
PMC3126667
AbstractArticlePDF–859K
17.
Cathepsin H Is an Additional Convertase of Pro-granzyme B
Michael E. D'Angelo, Phillip I. Bird, Christoph Peters, Thomas Reinheckel, Joseph A. Trapani, Vivien R. Sutton
J Biol Chem. 2010 Jul 2; 285(27): 20514–20519. Published online 2010 Apr 30. doi: 10.1074/jbc.M109.094573
PMCID:
PMC2898313
AbstractArticlePDF–843K
18.
Transcriptional profiling of Wnt4 mutant mouse kidneys identifies genes expressed during nephron formation
M. Todd Valerius, Andrew P. McMahon
Gene Expr Patterns. Author manuscript; available in PMC 2009 May 1.
Published in final edited form as: Gene Expr Patterns. 2008 May; 8(5): 297–306. Published online 2008 Feb 9. doi: 10.1016/j.gep.2008.02.001
PMCID:
PMC2435058
AbstractArticlePDF–2.1M
19.
BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System
Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran
PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086
PMCID:
PMC1413568
ArticlePDF–99K
20.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M

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