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Select item 102536251.

Recombinant SARS-CoV-2 Spike Protein Stimulates Secretion of Chymase, Tryptase, and IL-1β from Human Mast Cells, Augmented by IL-33

Irene Tsilioni, Theoharis C. Theoharides

Int J Mol Sci. 2023 Jun; 24(11): 9487. Published online 2023 May 30. doi: 10.3390/ijms24119487

PMCID:: PMC10253625

Abstract Article PDF–1.1M

Select item 101796952.

Increased Chymase-Positive Mast Cells in High-Grade Mucoepidermoid Carcinoma of the Parotid Gland

Hiromi Nishimura, Denan Jin, Ichita Kinoshita, Masataka Taniuchi, Masaaki Higashino, Tetsuya Terada, Shinji Takai, Ryo Kawata

Int J Mol Sci. 2023 May; 24(9): 8267. Published online 2023 May 5. doi: 10.3390/ijms24098267

PMCID:: PMC10179695

Abstract Article PDF–7.9M

Select item 86576263.

Increase in Chymase-Positive Mast Cells in Recurrent Pleomorphic Adenoma and Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland

Ichita Kinoshita, Denan Jin, Masaaki Higashino, Tetsuya Terada, Yoshitaka Kurisu, Shinji Takai, Ryo Kawata

Int J Mol Sci. 2021 Dec; 22(23): 12613. Published online 2021 Nov 23. doi: 10.3390/ijms222312613

PMCID:: PMC8657626

Abstract Article PDF–7.9M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81273385.

The Angiotensin-(1-12)/Chymase Axis as an Alternate Component of the Tissue Renin Angiotensin System

Carlos M. Ferrario, Leanne Groban, Hao Wang, Che Ping Cheng, Jessica VonCannon, Kendra N Wright, Sun Xuming, Sarfaraz Ahmad

Mol Cell Endocrinol. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: Mol Cell Endocrinol. 2021 Jun 1; 529: 111119. Published online 2020 Dec 10. doi: 10.1016/j.mce.2020.111119

PMCID:: PMC8127338

Abstract Article PDF–495K

Select item 76138926.

Investigation into the Health Effects of Reduced Chymase Function Using Predicted Loss-of-Function Mutations in CMA1

Zammy Fairhurst-Hunter, Robin G. Walters, Alexander Zink, Kuang Lin, Yu Guo, Canqing Yu, Jun Lv, Liming Li, Daniel F. Freitag, Zhengming Chen, Iona Y. Millwood

J Cardiovasc Transl Res. 2022; 15(6): 1474–1476. Published online 2022 May 5. doi: 10.1007/s12265-022-10261-w

PMCID:: PMC7613892

Abstract Article PDF–593K

Select item 73849567.

Differential Expression of the Angiotensin-(1-12)/chymase Axis in Human Atrial Tissue

Hao Wang, Jasmina Varagic, Sayaka Nagata, Neal D. Kon, Sarfaraz Ahmad, Jessica L. VonCannon, Kendra N. Wright, Xuming Sun, Dwight Deal, Leanne Groban, Carlos M. Ferrario

J Surg Res. Author manuscript; available in PMC 2021 Sep 1.

Published in final edited form as: J Surg Res. 2020 Sep; 253: 173–184. Published online 2020 Apr 30. doi: 10.1016/j.jss.2020.03.051

PMCID:: PMC7384956

Abstract Article PDF–453K

Select item 73672728.

Serum chymase levels correlate with severe dengue warning signs and clinical fluid accumulation in hospitalized pediatric patients

Abhay P. S. Rathore, Manouri Senanayake, Arjuna Salinda Athapathu, Sunethra Gunasena, Irantha Karunaratna, Wei Yee Leong, Ting Lim, Chinmay Kumar Mantri, Annelies Wilder-Smith, Ashley L. St. John

Sci Rep. 2020; 10: 11856. Published online 2020 Jul 16. doi: 10.1038/s41598-020-68844-z

PMCID:: PMC7367272

Abstract Article PDF–3.4M

Select item 69360499.

Association between chymase gene polymorphisms and atrial fibrillation in Chinese Han population

Dongchen Zhou, Yuewei Chen, Jiaxin Wu, Jiabo Shen, Yushan Shang, Liangrong Zheng, Xudong Xie

BMC Cardiovasc Disord. 2019; 19: 321. Published online 2019 Dec 30. doi: 10.1186/s12872-019-01300-7

PMCID:: PMC6936049

Abstract Article PDF–498K

Select item 676327110.

Mast cell peptidases (carboxypeptidase A and chymase)-mediated hydrolysis of human angiotensin-(1–12) substrate

Sarfaraz Ahmad, Kendra N. Wright, Xuming Sun, Leanne Groban, Carlos M. Ferrario

Biochem Biophys Res Commun. Author manuscript; available in PMC 2019 Oct 22.

Published in final edited form as: Biochem Biophys Res Commun. 2019 Oct 22; 518(4): 651–656. Published online 2019 Aug 26. doi: 10.1016/j.bbrc.2019.08.098

PMCID:: PMC6763271

Abstract Article PDF–558K

Select item 616668211.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 603321112.

Chemerin 156F, generated by chymase cleavage of prochemerin, is elevated in joint fluids of arthritis patients

Lei Zhao, Yasuto Yamaguchi, Xiaomei Ge, William H. Robinson, John Morser, Lawrence L. K. Leung

Arthritis Res Ther. 2018; 20: 132. Published online 2018 Jul 4. doi: 10.1186/s13075-018-1615-y

PMCID:: PMC6033211

Abstract Article PDF–1.2M

Select item 584672113.

Transmembrane protease, serine 4 (TMPRSS4) is upregulated in IPF lungs and increases the fibrotic response in bleomycin-induced lung injury

Ana Valero-Jiménez, Joaquín Zúñiga, José Cisneros, Carina Becerril, Alfonso Salgado, Marco Checa, Ivette Buendía-Roldán, Criselda Mendoza-Milla, Miguel Gaxiola, Annie Pardo, Moisés Selman

PLoS One. 2018; 13(3): e0192963. Published online 2018 Mar 12. doi: 10.1371/journal.pone.0192963

PMCID:: PMC5846721

Abstract Article PDF–17M

Select item 531196614.

Hypoxia-induced angiotensin II by the lactate-chymase-dependent mechanism mediates radioresistance of hypoxic tumor cells

Guozhu Xie, Ying Liu, Qiwei Yao, Rong Zheng, Lanfang Zhang, Jie Lin, Zhaoze Guo, Shasha Du, Chen Ren, Quan Yuan, Yawei Yuan

Sci Rep. 2017; 7: 42396. Published online 2017 Feb 16. doi: 10.1038/srep42396

PMCID:: PMC5311966

Abstract Article PDF–2.0M

Select item 508109615.

Glycoproteomics Reveals Decorin Peptides with Anti-Myostatin Activity in Human Atrial Fibrillation

Javier Barallobre-Barreiro, Shashi K. Gupta, Anna Zoccarato, Rika Kitazume-Taneike, Marika Fava, Xiaoke Yin, Tessa Werner, Marc N Hirt, Anna Zampetaki, Alessandro Viviano, Mei Chong, Marshall Bern, Antonios Kourliouros, Nieves Domenech, Peter Willeit, Ajay M Shah, Marjan Jahangiri, Liliana Schaefer, Jens W. Fischer, Renato V. Iozzo, Rosa Viner, Thomas Thum, Joerg Heineke, Antoine Kichler, Kinya Otsu, Manuel Mayr

Circulation. Author manuscript; available in PMC 2017 Mar 13.

Published in final edited form as: Circulation. 2016 Sep 13; 134(11): 817–832. Published online 2016 Aug 24. doi: 10.1161/CIRCULATIONAHA.115.016423

PMCID:: PMC5081096

Abstract Article PDF–2.5M

Select item 487287916.

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

Javier Barallobre-Barreiro, Rahmi Oklu, Marc Lynch, Marika Fava, Ferheen Baig, Xiaoke Yin, Temo Barwari, David N. Potier, Hassan Albadawi, Marjan Jahangiri, Karen E. Porter, Michael T. Watkins, Sanjay Misra, Julianne Stoughton, Manuel Mayr

Cardiovasc Res. 2016 Jun 1; 110(3): 419–430. Published online 2016 Apr 11. doi: 10.1093/cvr/cvw075

PMCID:: PMC4872879

Abstract Article PDF–1.1M

Select item 412897217.

Mast cell chymase in keloid induces profibrotic response via transforming growth factor-β₁/Smad activation in keloid fibroblasts

Xianglin Dong, Chuanshan Zhang, Shaolin Ma, Hao Wen

Int J Clin Exp Pathol. 2014; 7(7): 3596–3607. Published online 2014 Jun 15.

PMCID:: PMC4128972

Abstract Article PDF–1.4M

Select item 411506218.

Development of Mast Cells and Importance of Their Tryptase and Chymase Serine Proteases in Inflammation and Wound Healing

Jeffrey Douaiher, Julien Succar, Luca Lancerotto, Michael F. Gurish, Dennis P. Orgill, Matthew J. Hamilton, Steven A. Krilis, Richard L. Stevens

Adv Immunol. Author manuscript; available in PMC 2014 Jul 29.

Published in final edited form as: Adv Immunol. 2014; 122: 211–252. doi: 10.1016/B978-0-12-800267-4.00006-7

PMCID:: PMC4115062

Abstract Article PDF–821K

Select item 403861119.

Altered Immunohistochemical Expression of Mast Cell Tryptase and Chymase in the Pathogenesis of Oral Submucous Fibrosis and Malignant Transformation of the Overlying Epithelium

Archana Yadav, Rajiv S. Desai, Bansari A. Bhuta, Jatinder S. Singh, Reema Mehta, Akash P. Nehete

PLoS One. 2014; 9(5): e98719. Published online 2014 May 29. doi: 10.1371/journal.pone.0098719

PMCID:: PMC4038611

Abstract Article PDF–14M

Select item 401948020.

Association of the Common Genetic Polymorphisms and Haplotypes of the Chymase Gene with Left Ventricular Mass in Male Patients with Symptomatic Aortic Stenosis

Ewa Orlowska-Baranowska, Jaroslaw Gora, Rafal Baranowski, Patrycjusz Stoklosa, Lucja Gadomska vel Betka, Ewa Pedzich-Placha, Malogrzata Milkowska, Marta K. Koblowska, Tomasz Hryniewiecki, Zbigniew Gaciong, Grzegorz Placha

PLoS One. 2014; 9(5): e96306. Published online 2014 May 13. doi: 10.1371/journal.pone.0096306

PMCID:: PMC4019480

Abstract Article PDF–648K

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