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Select item 105658761.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 104700532.

Diverse p120RasGAP interactions with doubly phosphorylated partners EphB4, p190RhoGAP, and Dok1

Kimberly J. Vish, Amy L. Stiegler, Titus J. Boggon

J Biol Chem. 2023 Sep; 299(9): 105098. Published online 2023 Jul 27. doi: 10.1016/j.jbc.2023.105098

PMCID:: PMC10470053

Abstract Article PDF–3.2M

Select item 85735223.

Docking protein 1 and free fatty acids are associated with insulin resistance in patients with type 2 diabetes mellitus

Xiaoqin Ha, Xiaoling Cai, Huizhe Cao, Jie Li, Bo Yang, Ruru Jiang, Xin Li, Bin Li, Yuan Xin

J Int Med Res. 2021 Nov; 49(11): 03000605211048293. Published online 2021 Nov 2. doi: 10.1177/03000605211048293

PMCID:: PMC8573522

Abstract Article PDF–519K

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 68858765.

Nck adapter proteins promote podosome biogenesis facilitating extracellular matrix degradation and cancer invasion

Sankar P. Chaki, Rola Barhoumi, Gonzalo M. Rivera

Cancer Med. 2019 Dec; 8(17): 7385–7398. Published online 2019 Oct 22. doi: 10.1002/cam4.2640

PMCID:: PMC6885876

Abstract Article PDF–2.0M

Select item 55316116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 55283027.

Characterization of DOK1, a candidate tumor suppressor gene, in epithelial ovarian cancer

Pierre-Luc Mercier, Magdalena Bachvarova, Marie Plante, Jean Gregoire, Marie-Claude Renaud, Karim Ghani, Bernard Têtu, Isabelle Bairati, Dimcho Bachvarov

Mol Oncol. 2011 Oct; 5(5): 438–453. Published online 2011 Jul 26. doi: 10.1016/j.molonc.2011.07.003

PMCID:: PMC5528302

Abstract Article PDF–1.6M

Select item 49195728.

Subcellular compartmentalization of docking protein-1 contributes to progression in colorectal cancer

Teresa Friedrich, Michaela Söhn, Tobias Gutting, Klaus-Peter Janssen, Hans-Michael Behrens, Christoph Röcken, Matthias P.A. Ebert, Elke Burgermeister

EBioMedicine. 2016 Jun; 8: 159–172. Published online 2016 May 5. doi: 10.1016/j.ebiom.2016.05.003

PMCID:: PMC4919572

Abstract Article PDF–2.5M

Select item 48317879.

RASSF1A and DOK1 Promoter Methylation Levels in Hepatocellular Carcinoma, Cirrhotic and Non-Cirrhotic Liver, and Correlation with Liver Cancer in Brazilian Patients

Oscar C. Araújo, Agatha S. Rosa, Arlete Fernandes, Christian Niel, Cristiane A. Villela-Nogueira, Vera Pannain, Natalia M. Araujo

PLoS One. 2016; 11(4): e0153796. Published online 2016 Apr 14. doi: 10.1371/journal.pone.0153796

PMCID:: PMC4831787

Abstract Article PDF–384K

Select item 461721110.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 447998611.

An Alternative Phosphorylation Switch in Integrin β2 (CD18) Tail for Dok1 Binding

Sebanti Gupta, Joel Chia-Yeong Chit, Chen Feng, Anirban Bhunia, Suet-Mien Tan, Surajit Bhattacharjya

Sci Rep. 2015; 5: 11630. Published online 2015 Jun 25. doi: 10.1038/srep11630

PMCID:: PMC4479986

Abstract Article PDF–2.1M

Select item 438092812.

Phospho-tyrosine dependent protein–protein interaction network

Arndt Grossmann, Nouhad Benlasfer, Petra Birth, Anna Hegele, Franziska Wachsmuth, Luise Apelt, Ulrich Stelzl

Mol Syst Biol. 2015 Mar; 11(3): 0794. Published online 2015 Mar 26. doi: 10.15252/msb.20145968

PMCID:: PMC4380928

Abstract Article PDF–1.9M

Select item 436785713.

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing

Fernanda Luisa Basei, Gabriela Vaz Meirelles, Germanna Lima Righetto, Deivid Lucas dos Santos Migueleti, Juliana Helena Costa Smetana, Jörg Kobarg

Proteome Sci. 2015; 13: 11. Published online 2015 Feb 26. doi: 10.1186/s12953-015-0065-6

PMCID:: PMC4367857

Abstract Article PDF–3.1M

Select item 430206814.

Phosphorylation of Dok1 by Abl family kinases inhibits CrkI transforming activity

Khong Y. Ng, Taofei Yin, Kazuya Machida, Yi I. Wu, Bruce J. Mayer

Oncogene. Author manuscript; available in PMC 2015 Nov 14.

Published in final edited form as: Oncogene. 2015 May 14; 34(20): 2650–2659. Published online 2014 Jul 21. doi: 10.1038/onc.2014.210

PMCID:: PMC4302068

Abstract Article PDF–696K

Select item 419578715.

Dok1 and Dok2 proteins regulate natural killer cell development and function

Javier Celis-Gutierrez, Marilyn Boyron, Thierry Walzer, Pier Paolo Pandolfi, Stipan Jonjić, Daniel Olive, Marc Dalod, Eric Vivier, Jacques A Nunès

EMBO J. 2014 Sep 1; 33(17): 1928–1940. Published online 2014 Jun 24. doi: 10.15252/embj.201387404

PMCID:: PMC4195787

Abstract Article PDF–1.8M

Select item 401446316.

Epstein-Barr Virus Down-Regulates Tumor Suppressor DOK1 Expression

Maha Siouda, Cecilia Frecha, Rosita Accardi, Jiping Yue, Cyrille Cuenin, Henri Gruffat, Evelyne Manet, Zdenko Herceg, Bakary S. Sylla, Massimo Tommasino

PLoS Pathog. 2014 May; 10(5): e1004125. Published online 2014 May 8. doi: 10.1371/journal.ppat.1004125