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Items: 1 to 20 of 80

1.
Association of TMEM106B with Cortical APOE Gene Expression in Neurodegenerative Conditions
Cynthia Picard, Justin Miron, Judes Poirier
Genes (Basel) 2024 Apr; 15(4): 416. Published online 2024 Mar 26. doi: 10.3390/genes15040416
PMCID:
PMC11049136
AbstractArticlePDF–2.4M
2.
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia
Jordan D. Marks, Virginia Estades Ayuso, Yari Carlomagno, Mei Yue, Tiffany W. Todd, Ying Hao, Ziyi Li, Zachary T. McEachin, Anantharaman Shantaraman, Duc M. Duong, Lillian M. Daughrity, Karen Jansen-West, Wei Shao, Anna Calliari, Jesus Gonzalez Bejarano, Michael DeTure, Bailey Rawlinson, Monica Castanedes Casey, Meredith T. Lilley, Megan H. Donahue, Vidhya Maheswari Jawahar, Bradley F. Boeve, Ronald C. Petersen, David S. Knopman, Björn Oskarsson, Neill R. Graff-Radford, Zbigniew K. Wszolek, Dennis W. Dickson, Keith A. Josephs, Yue A. Qi, Nicholas T. Seyfried, Michael E. Ward, Yong-Jie Zhang, Mercedes Prudencio, Leonard Petrucelli, Casey N. Cook
Sci Transl Med. Author manuscript; available in PMC 2024 Feb 5.
Published in final edited form as: Sci Transl Med. 2024 Jan 17; 16(730): eadf9735. Published online 2024 Jan 17. doi: 10.1126/scitranslmed.adf9735
PMCID:
PMC10841341
AbstractArticlePDF–1.7M
3.
C-terminal TMEM106B fragments in human brain correlate with disease-associated TMEM106B haplotypes
Cristina T. Vicente, Jolien Perneel, Sarah Wynants, Bavo Heeman, Marleen Van den Broeck, Matt Baker, Simon Cheung, Júlia Faura, Ian R A Mackenzie, Rosa Rademakers
Brain. 2023 Oct; 146(10): 4055–4064. Published online 2023 Apr 26. doi: 10.1093/brain/awad133
PMCID:
PMC10545506
AbstractArticlePDF–570K
4.
TMEM106B Fibrils from FTLD Patients and Healthy Controls
James D. Greenwood, Wyatt C. Powell, Maciej A. Walczak
ACS Chem Neurosci. Author manuscript; available in PMC 2023 Sep 27.
Published in final edited form as: ACS Chem Neurosci. 2023 Aug 16; 14(16): 2827–2829. Published online 2023 Aug 2. doi: 10.1021/acschemneuro.3c00482
PMCID:
PMC10528478
AbstractArticlePDF–822K
5.
The major TMEM106B dementia risk allele affects TMEM106B protein levels, fibril formation, and myelin lipid homeostasis in the ageing human hippocampus
Jun Yup Lee, Dylan J Harney, Jonathan D Teo, John B Kwok, Greg T. Sutherland, Mark Larance, Anthony S Don
Mol Neurodegener. 2023; 18: 63. Published online 2023 Sep 19. doi: 10.1186/s13024-023-00650-3
Correction in:
Mol Neurodegener. 2024; 19: 21.
PMCID:
PMC10510131
AbstractArticlePDF–4.0M
6.
TMEM106B aggregation in neurodegenerative diseases: linking genetics to function
Hai-Shan Jiao, Peng Yuan, Jin-Tai Yu
Mol Neurodegener. 2023; 18: 54. Published online 2023 Aug 10. doi: 10.1186/s13024-023-00644-1
PMCID:
PMC10413548
AbstractArticlePDF–2.1M
7.
TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry
Jim Baggen, Maarten Jacquemyn, Leentje Persoons, Els Vanstreels, Valerie E. Pye, Antoni G. Wrobel, Valeria Calvaresi, Stephen R. Martin, Chloë Roustan, Nora B. Cronin, Eamonn Reading, Hendrik Jan Thibaut, Thomas Vercruysse, Piet Maes, Frederik De Smet, Angie Yee, Toey Nivitchanyong, Marina Roell, Natalia Franco-Hernandez, Herve Rhinn, Alusha Andre Mamchak, Maxime Ah Young-Chapon, Eric Brown, Peter Cherepanov, Dirk Daelemans
Cell. 2023 Aug 3; 186(16): 3427–3442.e22. doi: 10.1016/j.cell.2023.06.005
PMCID:
PMC10409496
AbstractArticlePDF–13M
8.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
9.
Amyloid fibrils in disease FTLD-TDP are composed of TMEM106B not TDP-43
Yi Xiao Jiang, Qin Cao, Michael R. Sawaya, Romany Abskharon, Peng Ge, Michael DeTure, Dennis W. Dickson, Janine Y. Fu, Rachel R. Ogorzalek Loo, Joseph A. Loo, David S. Eisenberg
Nature. Author manuscript; available in PMC 2023 Jan 17.
Published in final edited form as: Nature. 2022 May; 605(7909): 304–309. Published online 2022 Mar 28. doi: 10.1038/s41586-022-04670-9
PMCID:
PMC9844993
AbstractArticlePDF–5.7M
10.
Identification of TMEM106B amyloid fibrils provides an updated view of TMEM106B biology in health and disease
Jolien Perneel, Rosa Rademakers
Acta Neuropathol. 2022; 144(5): 807–819. Published online 2022 Sep 2. doi: 10.1007/s00401-022-02486-5
PMCID:
PMC9547799
AbstractArticlePDF–4.5M
11.
TMEM106B Acts as a Modifier of Cognitive and Motor Functions in Amyotrophic Lateral Sclerosis
Arianna Manini, Antonia Ratti, Alberto Brusati, Alessio Maranzano, Isabella Fogh, Silvia Peverelli, Stefano Messina, Davide Gentilini, Federico Verde, Barbara Poletti, Claudia Morelli, Vincenzo Silani, Nicola Ticozzi
Int J Mol Sci. 2022 Aug; 23(16): 9276. Published online 2022 Aug 17. doi: 10.3390/ijms23169276
PMCID:
PMC9408885
AbstractArticlePDF–772K
12.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
13.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
14.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M
15.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
16.
Age-dependent formation of TMEM106B amyloid filaments in human brains
Manuel Schweighauser, Diana Arseni, Mehtap Bacioglu, Melissa Huang, Sofia Lövestam, Yang Shi, Yang Yang, Wenjuan Zhang, Abhay Kotecha, Holly J. Garringer, Ruben Vidal, Grace I. Hallinan, Kathy L. Newell, Airi Tarutani, Shigeo Murayama, Masayuki Miyazaki, Yuko Saito, Mari Yoshida, Kazuko Hasegawa, Tammaryn Lashley, Tamas Revesz, Gabor G. Kovacs, John van Swieten, Masaki Takao, Masato Hasegawa, Bernardino Ghetti, Maria Grazia Spillantini, Benjamin Ryskeldi-Falcon, Alexey G. Murzin, Michel Goedert, Sjors H. W. Scheres
Nature. 2022; 605(7909): 310–314. Published online 2022 Mar 28. doi: 10.1038/s41586-022-04650-z
PMCID:
PMC9095482
AbstractArticlePDF–18M
17.
C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy
Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell
Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116
PMCID:
PMC9037554
AbstractArticlePDF–4.1M
18.
Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases
Andrew Chang, Xinyu Xiang, Jing Wang, Carolyn Lee, Tamta Arakhamia, Marija Simjanoska, Chi Wang, Yari Carlomagno, Guoan Zhang, Shikhar Dhingra, Manon Thierry, Jolien Perneel, Bavo Heeman, Lauren M. Forgrave, Michael DeTure, Mari L. DeMarco, Casey N. Cook, Rosa Rademakers, Dennis Dickson, Leonard Petrucelli, Michael H. B. Stowell, Ian R. A. Mackenzie, Anthony W. P. Fitzpatrick
Cell. Author manuscript; available in PMC 2023 Apr 14.
Published in final edited form as: Cell. 2022 Apr 14; 185(8): 1346–1355.e15. Published online 2022 Mar 4. doi: 10.1016/j.cell.2022.02.026
PMCID:
PMC9018563
AbstractArticlePDF–2.0M
19.
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396
PMCID:
PMC8552907
AbstractArticlePDF–3.9M
20.
Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs
Katherine M. Almasy, Jonathan P. Davies, Lars Plate
Mol Cell Proteomics. 2021; 20: 100120. Published online 2021 Jun 27. doi: 10.1016/j.mcpro.2021.100120
PMCID:
PMC8236078
AbstractArticlePDF–4.6M

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