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Select item 109424671.

Mitochondrial Raf1 Regulates Glutamine Catabolism

Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari

Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297

PMCID:: PMC10942467

Abstract Article PDF–6.5M

Select item 101602292.

More than just a histone deacetylase: cytoplasmic SIRT6 facilitates fatty acid oxidation through ACSL5 deacetylation: SIRT6-mediated ACSL5 deacetylation regulating FFA metabolism

Shuoshuo Li, Zengqiang Yuan

Acta Biochim Biophys Sin (Shanghai) 2023 Mar; 55(3): 525–527. Published online 2023 Mar 6. doi: 10.3724/abbs.2023030

PMCID:: PMC10160229

Article PDF–197K

Select item 98398683.

Lysophosphatidylcholine inhibits lung cancer cell proliferation by regulating fatty acid metabolism enzyme long‐chain acyl‐coenzyme A synthase 5

Linlin Zhang, Xuanqi Liu, Yifei Liu, Furong Yan, Yiming Zeng, Yuanlin Song, Hao Fang, Dongli Song, Xiangdong Wang

Clin Transl Med. 2023 Jan; 13(1): e1180. Published online 2023 Jan 13. doi: 10.1002/ctm2.1180

PMCID:: PMC9839868

Abstract Article PDF–8.1M

Select item 75113944.

A multi-ethnic meta-analysis identifies novel genes, including ACSL5, associated with amyotrophic lateral sclerosis

Ryoichi Nakamura, Kazuharu Misawa, Genki Tohnai, Masahiro Nakatochi, Sho Furuhashi, Naoki Atsuta, Naoki Hayashi, Daichi Yokoi, Hazuki Watanabe, Hirohisa Watanabe, Masahisa Katsuno, Yuishin Izumi, Kazuaki Kanai, Nobutaka Hattori, Mitsuya Morita, Akira Taniguchi, Osamu Kano, Masaya Oda, Kazumoto Shibuya, Satoshi Kuwabara, Naoki Suzuki, Masashi Aoki, Yasuyuki Ohta, Toru Yamashita, Koji Abe, Rina Hashimoto, Ikuko Aiba, Koichi Okamoto, Kouichi Mizoguchi, Kazuko Hasegawa, Yohei Okada, Tomohiko Ishihara, Osamu Onodera, Kenji Nakashima, Ryuji Kaji, Yoichiro Kamatani, Shiro Ikegawa, Yukihide Momozawa, Michiaki Kubo, Noriko Ishida, Naoko Minegishi, Masao Nagasaki, Gen Sobue

Commun Biol. 2020; 3: 526. Published online 2020 Sep 23. doi: 10.1038/s42003-020-01251-2

PMCID:: PMC7511394

Abstract Article PDF–1.4M

Select item 72170645.

ONECUT2 upregulation is associated with CpG hypomethylation at promoter‐proximal DNA in gastric cancer and triggers ACSL5

Eun‐Hye Seo, Hee‐Jin Kim, Jong‐Hwan Kim, Byungho Lim, Jong‐Lyul Park, Seon‐Young Kim, Sang‐Il Lee, Hyun‐Yong Jeong, Kyu‐Sang Song, Yong‐Sung Kim

Int J Cancer. 2020 Jun 15; 146(12): 3354–3368. Published online 2020 Mar 20. doi: 10.1002/ijc.32946

PMCID:: PMC7217064

Abstract Article PDF–3.3M

Select item 71699836.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 69812067.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS^G13D

Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch

Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9

PMCID:: PMC6981206

Abstract Article PDF–3.7M

Select item 68715228.

Splice-site variant in ACSL5: a marker promoting opposing effect on cell viability and protein expression

Iván Pérez-Núñez, Mohamad Karaky, María Fedetz, Cristina Barrionuevo, Guillermo Izquierdo, Fuencisla Matesanz, Antonio Alcina

Eur J Hum Genet. 2019 Dec; 27(12): 1836–1844. Published online 2019 May 3. doi: 10.1038/s41431-019-0414-5

PMCID:: PMC6871522

Abstract Article PDF–1.0M

Select item 66059909.

LOX and ACSL5 as potential relapse markers for pancreatic cancer patients

Weidong Ma, Ting Li, Si Wu, Jian Li, Xiuchao Wang, Hui Li

Cancer Biol Ther. 2019; 20(6): 787–798. Published online 2019 Feb 3. doi: 10.1080/15384047.2018.1564565

PMCID:: PMC6605990

Abstract Article PDF–2.2M

Select item 655243210.

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression

Jung-Sik Kim, Xiaoyuan He, Jie Liu, Zhijun Duan, Taeyeon Kim, Julia Gerard, Brian Kim, Manoj M. Pillai, William S. Lane, William S. Noble, Bogdan Budnik, Todd Waldman

J Biol Chem. 2019 May 31; 294(22): 8760–8772. Published online 2019 Apr 22. doi: 10.1074/jbc.RA119.007832

PMCID:: PMC6552432

Abstract Article PDF–3.5M

Select item 578004111.

Endosomal Rab cycles regulate Parkin-mediated mitophagy

Koji Yamano, Chunxin Wang, Shireen A Sarraf, Christian Münch, Reika Kikuchi, Nobuo N Noda, Yohei Hizukuri, Masato T Kanemaki, Wade Harper, Keiji Tanaka, Noriyuki Matsuda, Richard J Youle

eLife. 2018; 7: e31326. Published online 2018 Jan 23. doi: 10.7554/eLife.31326

PMCID:: PMC5780041

Abstract Article PDF–11M

Select item 570387812.

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery

Ramesh Kumar, Román González-Prieto, Zhenyu Xiao, Matty Verlaan-de Vries, Alfred C. O. Vertegaal

Nat Commun. 2017; 8: 1809. Published online 2017 Nov 27. doi: 10.1038/s41467-017-01900-x

PMCID:: PMC5703878

Abstract Article PDF–3.7M

Select item 554179813.

Acyl-CoA Synthetase 5 Promotes the Growth and Invasion of Colorectal Cancer Cells

Shihua Ding, Shaohui Tang, Min Wang, Donghai Wu, Haijian Guo

Can J Gastroenterol Hepatol. 2017; 2017: 7615736. Published online 2017 Jul 20. doi: 10.1155/2017/7615736

PMCID:: PMC5541798

Abstract Article PDF–4.6M

Select item 526093914.

Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease

Felipe Roberti Teixeira, Suzanne J. Randle, Shachi P. Patel, Tycho E.T. Mevissen, Grasilda Zenkeviciute, Tie Koide, David Komander, Heike Laman

Biochem J. 2016 Oct 15; 473(20): 3563–3580. Prepublished online 2016 Aug 8. Published online 2016 Oct 11. doi: 10.1042/BCJ20160387

PMCID:: PMC5260939

Abstract Article PDF–1.1M

Select item 511005315.

A splice variant in the ACSL5 gene relates migraine with fatty acid activation in mitochondria

Fuencisla Matesanz, María Fedetz, Cristina Barrionuevo, Mohamad Karaky, Antonio Catalá-Rabasa, Victor Potenciano, Raquel Bello-Morales, Jose-Antonio López-Guerrero, Antonio Alcina

Eur J Hum Genet. 2016 Nov; 24(11): 1572–1577. Published online 2016 May 18. doi: 10.1038/ejhg.2016.54

PMCID:: PMC5110053

Abstract Article PDF–998K

Select item 499245616.

Mitochondrial protein interaction mapping identifies new regulators of respiratory chain function

Brendan J. Floyd, Emily M. Wilkerson, Mike T. Veling, Catie E. Minogue, Chuanwu Xia, Emily T. Beebe, Russell L. Wrobel, Holly Cho, Laura S. Kremer, Charlotte L. Alston, Katarzyna A. Gromek, Brendan K. Dolan, Arne Ulbrich, Jonathan A. Stefely, Sarah L. Bohl, Kelly M. Werner, Adam Jochem, Michael S. Westphall, Jarred W. Rensvold, Robert W. Taylor, Holger Prokisch, Jung-Ja P. Kim, Joshua J. Coon, David J. Pagliarini

Mol Cell. Author manuscript; available in PMC 2017 Aug 18.

Published in final edited form as: Mol Cell. 2016 Aug 18; 63(4): 621–632. Published online 2016 Aug 4. doi: 10.1016/j.molcel.2016.06.033