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Select item 111049781.

Frizzled 1 and Wnt1 as new potential therapeutic targets in the traumatically injured spinal cord

Pau González, Carlos González-Fernández, Yolanda Campos-Martín, Manuela Mollejo, Melissa Carballosa-Gautam, Alexander Marcillo, Michael Norenberg, Francisco Javier Rodríguez

Cell Mol Life Sci. 2020 Nov; 77(22): 4631–4662. Published online 2020 Jan 3. doi: 10.1007/s00018-019-03427-4

PMCID:: PMC11104978

Abstract Article PDF–20M

Select item 92626142.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 92057723.

Epigenetic repression of Wnt receptors in AD: a role for Sirtuin2-induced H4K16ac deacetylation of Frizzled1 and Frizzled7 promoters

Ernest Palomer, Núria Martín-Flores, Sarah Jolly, Patricia Pascual-Vargas, Stefano Benvegnù, Marina Podpolny, Samuel Teo, Kadi Vaher, Takashi Saito, Takaomi C. Saido, Paul Whiting, Patricia C. Salinas

Mol Psychiatry. 2022; 27(7): 3024–3033. Published online 2022 Mar 16. doi: 10.1038/s41380-022-01492-z

PMCID:: PMC9205772

Abstract Article PDF–2.6M

Select item 88099044.

Protein disulfide isomerase family 6 promotes the imatinib-resistance of renal cell carcinoma by regulation of Wnt3a-Frizzled1 axis

Yong Huang, Ping He, Juan Ding

Bioengineered. 2021; 12(2): 12157–12166. Published online 2021 Dec 7. doi: 10.1080/21655979.2021.2005218

PMCID:: PMC8809904

Abstract Article PDF–2.3M

Select item 82808455.

LINC00942 Promotes Tumor Proliferation and Metastasis in Lung Adenocarcinoma via FZD1 Upregulation

Ronghua Wang, Xiuyun Wang, Jingtao Zhang, Yanpei Liu

Technol Cancer Res Treat. 2021; 20: 1533033820977526. Published online 2021 Jul 13. doi: 10.1177/1533033820977526

PMCID:: PMC8280845

Abstract Article PDF–1.5M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 63914707.

Hypermethylation of Frizzled1 is associated with Wnt/β-catenin signaling inactivation in mesenchymal stem cells of patients with steroid-associated osteonecrosis

Fei Wu, Jing Jiao, Feng Liu, Yue Yang, Shanfeng Zhang, Zhenhua Fang, Zhipeng Dai, Zhibo Sun

Exp Mol Med. 2019 Feb; 51(2): 23. Published online 2019 Feb 26. doi: 10.1038/s12276-019-0220-8

PMCID:: PMC6391470

Abstract Article PDF–2.6M

Select item 63357188.

Biological Analysis of Gene Expression and Clinical Variables Suggest FZD1 as a Novel Biomarker for Patients with Kashin-Beck Disease, an Endemic Osteoarthritis in China

Xi Wang, Yujie Ning, Pan Zhang, Lei Yang, Cheng Li, Rong Zhou, Xiong Guo

Dis Markers. 2019; 2019: 3736198. Published online 2019 Jan 3. doi: 10.1155/2019/3736198

PMCID:: PMC6335718

Abstract Article PDF–868K

Select item 56367039.

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families

Oksana Voloshanenko, Philipp Gmach, Jan Winter, Dominique Kranz, Michael Boutros

FASEB J. 2017 Nov; 31(11): 4832–4844. Published online 2017 Jul 21. doi: 10.1096/fj.201700144R

PMCID:: PMC5636703

Abstract Article

Select item 553161110.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 551913411.

Frizzled are colonic epithelial receptors for Clostridium difficile toxin B

Liang Tao, Jie Zhang, Paul Meraner, Alessio Tovaglieri, Xiaoqian Wu, Ralf Gerhard, Xinjun Zhang, William B. Stallcup, Ji Miao, Xi He, Julian G. Hurdle, David T. Breault, Abraham L. Brass, Min Dong

Nature. Author manuscript; available in PMC 2017 Jul 20.

Published in final edited form as: Nature. 2016 Oct 20; 538(7625): 350–355. Published online 2016 Sep 28. doi: 10.1038/nature19799

PMCID:: PMC5519134

Abstract Article PDF–4.1M

Select item 504747712.

Transcriptional Regulation of Frizzled-1 in Human Osteoblasts by Sp1

Shibing Yu, Laura M. Yerges-Armstrong, Yanxia Chu, Joseph M. Zmuda, Yingze Zhang

PLoS One. 2016; 11(10): e0163277. Published online 2016 Oct 3. doi: 10.1371/journal.pone.0163277

PMCID:: PMC5047477

Abstract Article PDF–1.7M

Select item 434454913.

Dysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases

Silvia A. Purro, Soledad Galli, Patricia C. Salinas

J Mol Cell Biol. 2014 Feb; 6(1): 75–80. doi: 10.1093/jmcb/mjt049

PMCID:: PMC4344549

Abstract Article PDF–371K

Select item 415204014.

Sox9 regulates hyperexpression of Wnt1 and Fzd1 in human osteosarcoma tissues and cells

Huancai Liu, Yanchun Chen, Fenghua Zhou, Linlin Jie, Leidong Pu, Jie Ju, Fengjie Li, Zhigang Dai, Xin Wang, Shuanhu Zhou

Int J Clin Exp Pathol. 2014; 7(8): 4795–4805. Published online 2014 Jul 15.

PMCID:: PMC4152040

Abstract Article PDF–1016K

Select item 387553815.

WNT Signaling Pathway Gene Polymorphisms and Risk of Hepatic Fibrosis and Inflammation in HCV-Infected Patients

Yanhong Liu, Hashem B. El-Serag, Li Jiao, JuSeog Lee, David Moore, Luis M. Franco, Shahriar Tavakoli-Tabasi, Spiridon Tsavachidis, Jill Kuzniarek, David J. Ramsey, Donna L. White

PLoS One. 2013; 8(12): e84407. Published online 2013 Dec 30. doi: 10.1371/journal.pone.0084407

PMCID:: PMC3875538

Abstract Article PDF–298K

Select item 375892716.

E2F1 effects on osteoblast differentiation and mineralization are mediated through up-regulation of frizzled-1

Shibing Yu, Laura M Yerges-Armstrong, Yanxia Chu, Joseph M. Zmuda, Yingze Zhang

Bone. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: Bone. 2013 Oct; 56(2): 234–241. Published online 2013 Jun 24. doi: 10.1016/j.bone.2013.06.019

PMCID:: PMC3758927

Abstract Article PDF–2.5M

Select item 366018217.

Uncovering novel actors in astrocyte–neuron crosstalk in Parkinson’s disease: the Wnt/β-catenin signaling cascade as the common final pathway for neuroprotection and self-repair

Bianca Marchetti, Francesca L’Episcopo, Maria Concetta Morale, Cataldo Tirolo, Nuccio Testa, Salvo Caniglia, Maria Francesca Serapide, Stefano Pluchino

Eur J Neurosci. Author manuscript; available in PMC 2013 May 21.

Published in final edited form as: Eur J Neurosci. 2013 May; 37(10): 1550–1563. Published online 2013 Mar 5. doi: 10.1111/ejn.12166

PMCID:: PMC3660182

Abstract Article PDF–1.4M

Select item 360524918.

Invasive colon cancer, but not non-invasive adenomas induce a gradient effect of Wnt pathway receptor frizzled 1 (Fz1) expression in the tumor microenvironment

Kestutis Planutis, Marina Planutiene, Anthony V Nguyen, Mary Pat Moyer, Randall F Holcombe

J Transl Med. 2013; 11: 50. Published online 2013 Feb 26. doi: 10.1186/1479-5876-11-50

PMCID:: PMC3605249

Abstract Article PDF–2.2M

Select item 357404219.

Genome-wide association Scan of dental caries in the permanent dentition

Xiaojing Wang, John R Shaffer, Zhen Zeng, Ferdouse Begum, Alexandre R Vieira, Jacqueline Noel, Ida Anjomshoaa, Karen T Cuenco, Myoung-Keun Lee, James Beck, Eric Boerwinkle, Marilyn C Cornelis, Frank B Hu, David R Crosslin, Cathy C Laurie, Sarah C Nelson, Kimberly F Doheny, Elizabeth W Pugh, Deborah E Polk, Robert J Weyant, Richard Crout, Daniel W McNeil, Daniel E Weeks, Eleanor Feingold, Mary L Marazita

BMC Oral Health. 2012; 12: 57. Published online 2012 Dec 21. doi: 10.1186/1472-6831-12-57

PMCID:: PMC3574042

Abstract Article PDF–3.4M

Select item 347780420.

A Census of Human Soluble Protein Complexes

Pierre C. Havugimana, G. Traver Hart, Tamás Nepusz, Haixuan Yang, Andrei L. Turinsky, Zhihua Li, Peggy I. Wang, Daniel R. Boutz, Vincent Fong, Sadhna Phanse, Mohan Babu, Stephanie A. Craig, Pingzhao Hu, Cuihong Wan, James Vlasblom, Vaqaarun-Nisa Dar, Alexander Bezginov, Gregory W. Clark, Gabriel C. Wu, Shoshana J. Wodak, Elisabeth R.M. Tillier, Alberto Paccanaro, Edward M. Marcotte, Andrew Emili

Cell. Author manuscript; available in PMC 2013 Aug 31.

Published in final edited form as: Cell. 2012 Aug 31; 150(5): 1068–1081. doi: 10.1016/j.cell.2012.08.011

PMCID:: PMC3477804

Abstract Article PDF–7.7M

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