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Select item 106277861.

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis

Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge

Life Sci Alliance. 2024 Jan; 7(1): e202302335. Published online 2023 Nov 6. doi: 10.26508/lsa.202302335

PMCID:: PMC10627786

Abstract Article PDF–5.2M

Select item 99169752.

An ELOVL2-Based Epigenetic Clock for Forensic Age Prediction: A Systematic Review

Ersilia Paparazzo, Vincenzo Lagani, Silvana Geracitano, Luigi Citrigno, Mirella Aurora Aceto, Antonio Malvaso, Francesco Bruno, Giuseppe Passarino, Alberto Montesanto

Int J Mol Sci. 2023 Feb; 24(3): 2254. Published online 2023 Jan 23. doi: 10.3390/ijms24032254

PMCID:: PMC9916975

Abstract Article PDF–12M

Select item 86747043.

ELOVL2 promotes cancer progression by inhibiting cell apoptosis in renal cell carcinoma

Ken Tanaka, Shuya Kandori, Shotaro Sakka, Satoshi Nitta, Kozaburo Tanuma, Masanobu Shiga, Yoshiyuki Nagumo, Hiromitsu Negoro, Takahiro Kojima, Bryan J. Mathis, Toru Shimazui, Makoto Watanabe, Taka-Aki Sato, Takafumi Miyamoto, Takashi Matsuzaka, Hitoshi Shimano, Hiroyuki Nishiyama

Oncol Rep. 2022 Feb; 47(2): 23. Published online 2021 Nov 26. doi: 10.3892/or.2021.8234

PMCID:: PMC8674704

Abstract Article PDF–1.9M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 75158985.

Improvements and inter-laboratory implementation and optimization of blood-based single-locus age prediction models using DNA methylation of the ELOVL2 promoter

Imene Garali, Mourad Sahbatou, Antoine Daunay, Laura G. Baudrin, Victor Renault, Yosra Bouyacoub, Jean-François Deleuze, Alexandre How-Kit

Sci Rep. 2020; 10: 15652. Published online 2020 Sep 24. doi: 10.1038/s41598-020-72567-6

PMCID:: PMC7515898

Abstract Article PDF–3.1M

Select item 74270236.

Association Between Genetic Variants in FADS1-FADS2 and ELOVL2 and Obesity, Lipid Traits, and Fatty Acids in Tunisian Population

Wided Khamlaoui, Sounira Mehri, Sonia Hammami, Souha Hammouda, Imed Chraeif, Roberto Elosua, Mohamed Hammami

Clin Appl Thromb Hemost. 2020 Jan-Dec; 26: 1076029620915286. Published online 2020 Jun 25. doi: 10.1177/1076029620915286

PMCID:: PMC7427023

Abstract Article PDF–234K

Select item 71699837.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 69239558.

MYCN and PRC1 cooperatively repress docosahexaenoic acid synthesis in neuroblastoma via ELOVL2

Yi Ding, Jie Yang, Yawen Ma, Tengteng Yao, Xingyu Chen, Shengfang Ge, Lihua Wang, Xianqun Fan

J Exp Clin Cancer Res. 2019; 38: 498. Published online 2019 Dec 19. doi: 10.1186/s13046-019-1492-5

PMCID:: PMC6923955

Abstract Article PDF–2.4M

Select item 68247219.

Genetic variants in ELOVL2 and HSD17B12 predict melanoma-specific survival

Wei Dai, Hongliang Liu, Xinyuan Xu, Ge Jie, Sheng Luo, Dakai Zhu, Christopher I. Amos, Shenying Fang, Jeffrey E. Lee, Xin Li, Hongmei Nan, Chunying Li, Qingyi Wei

Int J Cancer. Author manuscript; available in PMC 2019 Nov 15.

Published in final edited form as: Int J Cancer. 2019 Nov 15; 145(10): 2619–2628. Published online 2019 Feb 20. doi: 10.1002/ijc.32194

PMCID:: PMC6824721

Abstract Article PDF–508K

Select item 678524210.

Glioma Stem Cell Specific Super Enhancer Promotes Polyunsaturated Fatty Acid Synthesis to Support EGFR Signaling

Ryan C. Gimple, Reilly L. Kidwell, Leo J.Y. Kim, Tengqian Sun, Anthony D. Gromovsky, Qiulian Wu, Megan Wolf, Deguan Lv, Shruti Bhargava, Li Jiang, Briana C. Prager, Xiuxing Wang, Qing Ye, Zhe Zhu, Guoxin Zhang, Zhen Dong, Linjie Zhao, Derrick Lee, Junfeng Bi, Andrew E. Sloan, Paul S. Mischel, J. Mark Brown, Hu Cang, Tao Huan, Stephen C. Mack, Qi Xie, Jeremy N. Rich

Cancer Discov. Author manuscript; available in PMC 2020 Mar 1.

Published in final edited form as: Cancer Discov. 2019 Sep; 9(9): 1248–1267. Published online 2019 Jun 14. doi: 10.1158/2159-8290.CD-19-0061

PMCID:: PMC6785242

Abstract Article PDF–4.0M

Select item 669199511.

Human aging DNA methylation signatures are conserved but accelerated in cultured fibroblasts

Gabriel Sturm, Andres Cardenas, Marie-Abèle Bind, Steve Horvath, Shuang Wang, Yunzhang Wang, Sara Hägg, Michio Hirano, Martin Picard

Epigenetics. 2019; 14(10): 961–976. Published online 2019 Jun 12. doi: 10.1080/15592294.2019.1626651

PMCID:: PMC6691995

Abstract Article PDF–5.3M

Select item 649516312.

DHA intake interacts with ELOVL2 and ELOVL5 genetic variants to influence polyunsaturated fatty acids in human milk

Yixia Wu (吴义霞), Yan Wang (王烟), Huimin Tian (田慧敏), Tong Lu (通逯), Miao Yu (于苗), Wenhui Xu (徐文慧), Guoliang Liu (刘国良), Lin Xie (谢林)

J Lipid Res. 2019 May; 60(5): 1043–1049. Published online 2019 Mar 26. doi: 10.1194/jlr.M090951

PMCID:: PMC6495163

Abstract Article PDF–649K

Select item 612269713.

FADS1-FADS2 and ELOVL2 gene polymorphisms in susceptibility to autism spectrum disorders in Chinese children

Caihong Sun, Mingyang Zou, Xuelai Wang, Wei Xia, Yongjuan Ma, Shuang Liang, Yanqiu Hao, Lijie Wu, Songbin Fu

BMC Psychiatry. 2018; 18: 283. Published online 2018 Sep 4. doi: 10.1186/s12888-018-1868-7

PMCID:: PMC6122697

Abstract Article PDF–1.7M

Select item 597549314.

Roderick C. Slieker, Caroline L. Relton, Tom R. Gaunt, P. Eline Slagboom, Bastiaan T. Heijmans

Epigenetics Chromatin. 2018; 11: 25. Published online 2018 May 30. doi: 10.1186/s13072-018-0191-3

PMCID:: PMC5975493

Abstract Article PDF–1.6M

Select item 586189015.

Systemic Age-Associated DNA Hypermethylation of ELOVL2 Gene: In Vivo and In Vitro Evidences of a Cell Replication Process

Maria Giulia Bacalini, Joris Deelen, Chiara Pirazzini, Marco De Cecco, Cristina Giuliani, Catia Lanzarini, Francesco Ravaioli, Elena Marasco, Diana van Heemst, H. Eka D. Suchiman, Roderick Slieker, Enrico Giampieri, Rina Recchioni, Fiorella Mercheselli, Stefano Salvioli, Giovanni Vitale, Fabiola Olivieri, Annemieke M. W. Spijkerman, Martijn E. T. Dollé, John M. Sedivy, Gastone Castellani, Claudio Franceschi, Pieternella E. Slagboom, Paolo Garagnani

J Gerontol A Biol Sci Med Sci. 2017 Aug; 72(8): 1015–1023. Published online 2016 Sep 26. doi: 10.1093/gerona/glw185

Correction in:: J Gerontol A Biol Sci Med Sci. 2017 May; 72(5): 729.

PMCID:: PMC5861890

Abstract Article PDF–2.8M

Select item 553161116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 508288217.

Estrogen Enhances the Expression of the Polyunsaturated Fatty Acid Elongase Elovl2 via ERα in Breast Cancer Cells

Amanda González-Bengtsson, Abolfazl Asadi, Hui Gao, Karin Dahlman-Wright, Anders Jacobsson

PLoS One. 2016; 11(10): e0164241. Published online 2016 Oct 27. doi: 10.1371/journal.pone.0164241

PMCID:: PMC5082882

Abstract Article PDF–2.3M

Select item 469007318.

Single Nucleotide Polymorphisms in the FADS Gene Cluster but not the ELOVL2 Gene are Associated with Serum Polyunsaturated Fatty Acid Composition and Development of Allergy (in a Swedish Birth Cohort)

Malin Barman, Staffan Nilsson, Åsa Torinsson Naluai, Anna Sandin, Agnes E. Wold, Ann-Sofie Sandberg

Nutrients. 2015 Dec; 7(12): 10100–10115. Published online 2015 Dec 3. doi: 10.3390/nu7125521

PMCID:: PMC4690073

Abstract Article PDF–660K

Select item 464794119.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 412386220.

Genome-Wide Association Study of Plasma N6 Polyunsaturated Fatty Acids within the CHARGE Consortium

Weihua Guan, Brian T. Steffen, Rozenn N. Lemaitre, Jason H.Y. Wu, Toshiko Tanaka, Ani Manichaikul, Millennia Foy, Stephen S. Rich, Lu Wang, Jennifer A. Nettleton, Weihong Tang, Xiangjun Gu, Stafania Bandinelli, Irena B. King, Barbara McKnight, Bruce M. Psaty, David Siscovick, Luc Djousse, Yii-Der Ida Chen, Luigi Ferrucci, Myriam Fornage, Dariush Mozafarrian, Michael Y. Tsai, Lyn M. Steffen

Circ Cardiovasc Genet. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Circ Cardiovasc Genet. 2014 Jun; 7(3): 321–331. Published online 2014 May 13. doi: 10.1161/CIRCGENETICS.113.000208

PMCID:: PMC4123862

Abstract Article PDF–430K

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