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Select item 106068201.

Thrombin-Induced COX-2 Expression and PGE₂ Synthesis in Human Tracheal Smooth Muscle Cells: Role of PKCδ/Pyk2-Dependent AP-1 Pathway Modulation

Chien-Chung Yang, I-Ta Lee, Yan-Jyun Lin, Wen-Bin Wu, Li-Der Hsiao, Chuen-Mao Yang

Int J Mol Sci. 2023 Oct; 24(20): 15130. Published online 2023 Oct 13. doi: 10.3390/ijms242015130

PMCID:: PMC10606820

Abstract Article PDF–5.9M

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 100729063.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 95758074.

High expression of PYK2 is associated with poor prognosis and cancer progression in early-stage cervical carcinoma

Can Zhang, Xinghua Zhu, Yong Li, Jia Shao, Haibo Xu, Lei Chen, Youli Dan, Hua Jin, Aiqin He

Medicine (Baltimore) 2022 Oct 14; 101(41): e31178. Published online 2022 Oct 14. doi: 10.1097/MD.0000000000031178

PMCID:: PMC9575807

Abstract Article PDF–983K

Select item 91529725.

Proline-rich tyrosine kinase Pyk2 regulates deep vein thrombosis

Stefania Momi, Jessica Canino, Mauro Vismara, Luca Galgano, Emanuela Falcinelli, Giuseppe Guglielmini, Giulia Ciarrocca Taranta, Gianni Francesco Guidetti, Paolo Gresele, Mauro Torti, Ilaria Canobbio

Haematologica. 2022 Jun 1; 107(6): 1374–1383. Published online 2022 Feb 10. doi: 10.3324/haematol.2021.279703

PMCID:: PMC9152972

Abstract Article PDF–1.1M

Select item 87005926.

Pyk2 Stabilizes Striatal Medium Spiny Neuron Structure and Striatal-Dependent Action

Shannon L. Gourley, Kolluru D. Srikanth, Ellen P. Woon, Hava Gil-Henn

Cells. 2021 Dec; 10(12): 3442. Published online 2021 Dec 7. doi: 10.3390/cells10123442

PMCID:: PMC8700592

Abstract Article PDF–2.9M

Select item 83766397.

Colon and liver tissue damage detection using methylated SESN3 and PTK2B genes in circulating cell-free DNA in patients with acute graft-versus-host disease

Miguel Waterhouse, Sandra Pennisi, Dietmar Pfeifer, Max Deuter, Nikolas von Bubnoff, Florian Scherer, Tim Strüssmann, Claudia Wehr, Justus Duyster, Hartmut Bertz, Jürgen Finke, Jesus Duque-Afonso

Bone Marrow Transplant. 2021; 56(2): 327–333. Published online 2020 Oct 20. doi: 10.1038/s41409-020-01090-z

Correction in:: Bone Marrow Transplant. 2021; 56(10): 2616.

PMCID:: PMC8376639

Abstract Article PDF–709K

Select item 80464198.

The AXL-PYK2-PKCα axis as a nexus of stemness circuits in TNBC

Lohit Khera, Yaron Vinik, Flavio Maina, Sima Lev

Life Sci Alliance. 2021 Jun; 4(6): e202000985. Published online 2021 Mar 30. doi: 10.26508/lsa.202000985

PMCID:: PMC8046419

Abstract Article PDF–4.1M

Select item 78760009.

Rab22a-NeoF1 fusion protein promotes osteosarcoma lung metastasis through its secretion into exosomes

Li Zhong, Dan Liao, Jingjing Li, Wenqiang Liu, Jingxuan Wang, Cuiling Zeng, Xin Wang, Zhiliang Cao, Ruhua Zhang, Miao Li, Kuntai Jiang, Yi-Xin Zeng, Jianhua Sui, Tiebang Kang

Signal Transduct Target Ther. 2021; 6: 59. Published online 2021 Feb 11. doi: 10.1038/s41392-020-00414-1

PMCID:: PMC7876000

Abstract Article PDF–7.6M

Select item 773653110.

Inhibition of Pyk2 and Src activity improves Cx43 gap junction intercellular communication

Li Zheng, Andrew J. Trease, Kenichi Katsurada, Gaelle Spagnol, Hanjun Li, Wen Shi, Bin Duan, Kaushik P. Patel, Paul L. Sorgen

J Mol Cell Cardiol. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: J Mol Cell Cardiol. 2020 Dec; 149: 27–40. Published online 2020 Sep 18. doi: 10.1016/j.yjmcc.2020.09.004

PMCID:: PMC7736531

Abstract Article PDF–3.0M

Select item 752704911.

Pyk2 Regulates Human Papillomavirus Replication by Tyrosine Phosphorylation of the E2 Protein

Leny Jose, Marsha DeSmet, Elliot J. Androphy

J Virol. 2020 Oct; 94(20): e01110-20. Prepublished online 2020 Jul 29. Published online 2020 Sep 29. doi: 10.1128/JVI.01110-20

PMCID:: PMC7527049

Abstract Article PDF–1.8M

Select item 742732712.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 735800913.

CD56 regulates human NK cell cytotoxicity through Pyk2

Justin T Gunesch, Amera L Dixon, Tasneem AM Ebrahim, Melissa M Berrien-Elliott, Swetha Tatineni, Tejas Kumar, Everardo Hegewisch-Solloa, Todd A Fehniger, Emily M Mace

eLife. 2020; 9: e57346. Published online 2020 Jun 8. doi: 10.7554/eLife.57346

PMCID:: PMC7358009

Abstract Article PDF–3.1M

Select item 698120614.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS^G13D

Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch

Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9

PMCID:: PMC6981206

Abstract Article PDF–3.7M

Select item 674197515.

Interaction between Liprin-α and GIT1 Is Required for AMPA Receptor Targeting

Jaewon Ko, Seho Kim, Juli G. Valtschanoff, Hyewon Shin, Jae-Ran Lee, Morgan Sheng, Richard T. Premont, Richard J. Weinberg, Eunjoon Kim

J Neurosci. 2003 Mar 1; 23(5): 1667–1677. doi: 10.1523/JNEUROSCI.23-05-01667.2003

PMCID:: PMC6741975

Abstract Article PDF–1.3M

Select item 669413216.

HENA, heterogeneous network-based data set for Alzheimer’s disease

Elena Sügis, Jerome Dauvillier, Anna Leontjeva, Priit Adler, Valerie Hindie, Thomas Moncion, Vincent Collura, Rachel Daudin, Yann Loe-Mie, Yann Herault, Jean-Charles Lambert, Henning Hermjakob, Tal Pupko, Jean-Christophe Rain, Ioannis Xenarios, Jaak Vilo, Michel Simonneau, Hedi Peterson

Sci Data. 2019; 6: 151. Published online 2019 Aug 14. doi: 10.1038/s41597-019-0152-0

PMCID:: PMC6694132

Abstract Article PDF–2.8M

Select item 653226017.

PYK2 promotes HER2-positive breast cancer invasion

Shaymaa IK. Al-Juboori, Jayakumar Vadakekolathu, Sarra Idri, Sarah Wagner, Dimitrios Zafeiris, Joshua RD. Pearson, Rukaia Almshayakhchi, Michele Caraglia, Vincenzo Desiderio, Amanda K. Miles, David J. Boocock, Graham R. Ball, Tarik Regad

J Exp Clin Cancer Res. 2019; 38: 210. Published online 2019 May 22. doi: 10.1186/s13046-019-1221-0

PMCID:: PMC6532260

Abstract Article PDF–4.3M

Select item 652770518.

FAK and Pyk2 activity promote TNF-α and IL-1β-mediated pro-inflammatory gene expression and vascular inflammation

James M. Murphy, Kyuho Jeong, Yelitza A. R. Rodriguez, Jung-Hyun Kim, Eun-Young Erin Ahn, Ssang-Taek Steve Lim

Sci Rep. 2019; 9: 7617. Published online 2019 May 20. doi: 10.1038/s41598-019-44098-2

PMCID:: PMC6527705

Abstract Article PDF–2.9M

Select item 623068719.

The human ion channel TRPM2 modulates neuroblastoma cell survival and mitochondrial function through Pyk2, CREB, and MCU activation

Iwona Hirschler-Laszkiewicz, Shu-jen Chen, Lei Bao, JuFang Wang, Xue-Qian Zhang, Santhanam Shanmughapriya, Kerry Keefer, Muniswamy Madesh, Joseph Y. Cheung, Barbara A. Miller

Am J Physiol Cell Physiol. 2018 Oct 1; 315(4): C571–C586. Published online 2018 Jul 18. doi: 10.1152/ajpcell.00098.2018

PMCID:: PMC6230687

Abstract Article

Select item 615515120.

PYK2 negatively regulates the Hippo pathway in TNBC by stabilizing TAZ protein

Amir Kedan, Nandini Verma, Ashish Saroha, Michal Shreberk-Shaked, Anna-Katharina Müller, Nishanth Ulhas Nair, Sima Lev

Cell Death Dis. 2018 Oct; 9(10): 985. Published online 2018 Sep 24. doi: 10.1038/s41419-018-1005-z

PMCID:: PMC6155151

Abstract Article PDF–5.4M

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