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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 87242782.

Mutations of MSH5 in nonobstructive azoospermia (NOA) and rescued via in vivo gene editing

Min Chen, Chencheng Yao, Yingying Qin, Xiuhong Cui, Peng Li, Zhiyong Ji, Limei Lin, Haowei Wu, Zhi Zhou, Yaoting Gui, Zheng Li, Fei Gao

Signal Transduct Target Ther. 2022; 7: 1. Published online 2022 Jan 3. doi: 10.1038/s41392-021-00710-4

PMCID:: PMC8724278

Article PDF–1.6M

Select item 72480693.

The BCL-2 pathway preserves mammalian genome integrity by eliminating recombination-defective oocytes

Elias ElInati, Agata P. Zielinska, Afshan McCarthy, Nada Kubikova, Valdone Maciulyte, Shantha Mahadevaiah, Mahesh N. Sangrithi, Obah Ojarikre, Dagan Wells, Kathy K. Niakan, Melina Schuh, James M. A. Turner

Nat Commun. 2020; 11: 2598. Published online 2020 May 25. doi: 10.1038/s41467-020-16441-z

PMCID:: PMC7248069

Abstract Article PDF–4.7M

Select item 57850334.

MORC2B is essential for meiotic progression and fertility

Baolu Shi, Jiangyang Xue, Jian Zhou, Seth D. Kasowitz, Yuanwei Zhang, Guanxiang Liang, Yongjuan Guan, Qinghua Shi, Mingxi Liu, Jiahao Sha, Xiaoyan Huang, P. Jeremy Wang

PLoS Genet. 2018 Jan; 14(1): e1007175. Published online 2018 Jan 12. doi: 10.1371/journal.pgen.1007175

PMCID:: PMC5785033

Abstract Article PDF–19M

Select item 54512305.

Transcription factors SOHLH1 and SOHLH2 coordinate oocyte differentiation without affecting meiosis I

Yong-Hyun Shin, Yu Ren, Hitomi Suzuki, Kayla J. Golnoski, Hyo won Ahn, Vasil Mico, Aleksandar Rajkovic

J Clin Invest. 2017 Jun 1; 127(6): 2106–2117. Published online 2017 May 15. doi: 10.1172/JCI90281

PMCID:: PMC5451230

Abstract Article PDF–6.0M

Select item 53931456.

Mutations in MSH5 in primary ovarian insufficiency

Ting Guo, Shidou Zhao, Shigang Zhao, Min Chen, Guangyu Li, Xue Jiao, Zhao Wang, Yueran Zhao, Yingying Qin, Fei Gao, Zi-Jiang Chen

Hum Mol Genet. 2017 Apr 15; 26(8): 1452–1457. Published online 2017 Feb 8. doi: 10.1093/hmg/ddx044

PMCID:: PMC5393145

Abstract Article PDF–615K

Select item 49702137.

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA

Xiaoyun Liu, Yan Jiao, Yanhong Cao, Nan Deng, Yonghui Ma, Karen A. Hasty, Andrew Kang, Hong Chen, John M. Stuart, Weikuan Gu

BMC Immunol. 2016; 17: 25. Published online 2016 Aug 2. doi: 10.1186/s12865-016-0163-y

PMCID:: PMC4970213

Abstract Article PDF–2.5M

Select item 36643628.

Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression

Adriana C. Ene, Stephanie Park, Winfried Edelmann, Teruko Taketo

Dev Biol. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Dev Biol. 2013 May 1; 377(1): 213–223. Published online 2013 Feb 4. doi: 10.1016/j.ydbio.2013.01.027

Correction in:: Dev Biol. 2020 Aug 13

PMCID:: PMC3664362

Abstract Article PDF–5.1M

Select item 35724109.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 317805910.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 317164911.

Evidence for a direct involvement of hMSH5 in promoting ionizing radiation induced apoptosis

JOSHUA D. TOMPKINS, XILING WU, YEN-LIN CHU, CHENGTAO HER

Exp Cell Res. Author manuscript; available in PMC 2011 Sep 13.

Published in final edited form as: Exp Cell Res. 2009 Aug 15; 315(14): 2420–2432. Published online 2009 May 12. doi: 10.1016/j.yexcr.2009.05.004

PMCID:: PMC3171649

Abstract Article PDF–1.9M

Select item 302253412.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 265636213.

Reassessment of the Role of Mut S Homolog 5 in Ig Class Switch Recombination Shows Lack of Involvement in cis- and trans-Switching

Jeroen E. J. Guikema, Carol E. Schrader, Niek G. J. Leus, Anna Ucher, Erin K. Linehan, Uwe Werling, Winfried Edelmann, Janet Stavnezer

J Immunol. Author manuscript; available in PMC 2009 Dec 15.

Published in final edited form as: J Immunol. 2008 Dec 15; 181(12): 8450–8459. doi: 10.4049/jimmunol.181.12.8450

PMCID:: PMC2656362

Abstract Article PDF–1.8M

Select item 248352314.

Extensive meiotic asynapsis in mice antagonises meiotic silencing of unsynapsed chromatin and consequently disrupts meiotic sex chromosome inactivation

Shantha K. Mahadevaiah, Déborah Bourc'his, Dirk G. de Rooij, Timothy H. Bestor, James M.A. Turner, Paul S. Burgoyne

J Cell Biol. 2008 Jul 28; 182(2): 263–276. doi: 10.1083/jcb.200710195

PMCID:: PMC2483523

Abstract Article PDF–2.9M

Select item 217124315.

Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I

Nadine K. Kolas, Anton Svetlanov, Michelle L. Lenzi, Frank P. Macaluso, Steven M. Lipkin, R. Michael Liskay, John Greally, Winfried Edelmann, Paula E. Cohen

J Cell Biol. 2005 Nov 7; 171(3): 447–458. doi: 10.1083/jcb.200506170

PMCID:: PMC2171243

Abstract Article PDF–4.2M

Select item 185537016.

Role for Msh5 in the regulation of Ig class switch recombination

Hideharu Sekine, Ricardo C. Ferreira, Qiang Pan-Hammarström, Robert R. Graham, Beth Ziemba, Sandra S. de Vries, Jiabin Liu, Keli Hippen, Thearith Koeuth, Ward Ortmann, Akiko Iwahori, Margaret K. Elliott, Steven Offer, Cara Skon, Likun Du, Jill Novitzke, Annette T. Lee, Nianxi Zhao, Joshua D. Tompkins, David Altshuler, Peter K. Gregersen, Charlotte Cunningham-Rundles, Reuben S. Harris, Chengtao Her, David L. Nelson, Lennart Hammarström, Gary S. Gilkeson, Timothy W. Behrens

Proc Natl Acad Sci U S A. 2007 Apr 24; 104(17): 7193–7198. Published online 2007 Apr 4. doi: 10.1073/pnas.0700815104

PMCID:: PMC1855370

Abstract Article PDF–865K

Select item 119025617.

Surveillance of Different Recombination Defects in Mouse Spermatocytes Yields Distinct Responses despite Elimination at an Identical Developmental Stage

Marco Barchi, Shantha Mahadevaiah, Monica Di Giacomo, Frédéric Baudat, Dirk G. de Rooij, Paul S. Burgoyne, Maria Jasin, Scott Keeney

Mol Cell Biol. 2005 Aug; 25(16): 7203–7215. doi: 10.1128/MCB.25.16.7203-7215.2005

PMCID:: PMC1190256

Abstract Article PDF–1.7M

Select item 54553218.

Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants

Monica Di Giacomo, Marco Barchi, Frédéric Baudat, Winfried Edelmann, Scott Keeney, Maria Jasin

Proc Natl Acad Sci U S A. 2005 Jan 18; 102(3): 737–742. Published online 2005 Jan 7. doi: 10.1073/pnas.0406212102

PMCID:: PMC545532

Abstract Article PDF–651K

Select item 40380419.

Analysis of the Gene-Dense Major Histocompatibility Complex Class III Region and Its Comparison to Mouse

Tao Xie, Lee Rowen, Begoña Aguado, Mary Ellen Ahearn, Anup Madan, Shizhen Qin, R. Duncan Campbell, Leroy Hood

Genome Res. 2003 Dec; 13(12): 2621–2636. doi: 10.1101/gr.1736803

PMCID:: PMC403804

Abstract Article PDF–901K

Select item 31657220.

MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice

Burkhard Kneitz, Paula E. Cohen, Elena Avdievich, Liyin Zhu, Michael F. Kane, Harry Hou, Jr., Richard D. Kolodner, Raju Kucherlapati, Jeffrey W. Pollard, Winfried Edelmann

Genes Dev. 2000 May 1; 14(9): 1085–1097.

PMCID:: PMC316572

Abstract Article PDF–8.3M

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