PMC Links for GEO Profiles (Select 130496485) - PMC

Select item 107177041.

Identification of the multivalent PDZ protein PDZK1 as a binding partner of sodium–coupled monocarboxylate transporter SMCT1 (SLC5A8) and SMCT2 (SLC5A12)

Sunena Srivastava, Kiyoshi Nakagawa, Xin He, Toru Kimura, Toshiyuki Fukutomi, Seiji Miyauchi, Hiroyuki Sakurai, Naohiko Anzai

J Physiol Sci. 2019 Mar; 69(2): 399–408. Published online 2019 Jan 2. doi: 10.1007/s12576-018-00658-1

PMCID:: PMC10717704

Abstract Article PDF–1.0M

Select item 89271122.

Gut-derived butyrate suppresses ocular surface inflammation

Laura Schaefer, Humberto Hernandez, Rosalind A. Coats, Zhiyuan Yu, Stephen C. Pflugfelder, Robert A. Britton, Cintia S. de Paiva

Sci Rep. 2022; 12: 4512. Published online 2022 Mar 16. doi: 10.1038/s41598-022-08442-3

Correction in:: Sci Rep. 2022; 12: 6581.

PMCID:: PMC8927112

Abstract Article PDF–1.7M

Select item 87442353.

Monocarboxylate transporter functions and neuroprotective effects of valproic acid in experimental models of amyotrophic lateral sclerosis

Asmita Gyawali, Sana Latif, Seung-Hye Choi, Seung Jae Hyeon, Hoon Ryu, Young-Sook Kang

J Biomed Sci. 2022; 29: 2. Published online 2022 Jan 10. doi: 10.1186/s12929-022-00785-3

PMCID:: PMC8744235

Abstract Article PDF–4.7M

Select item 75025084.

Reducing monocarboxylate transporter MCT1 worsens experimental diabetic peripheral neuropathy

Mithilesh Kumar Jha, Xanthe H. Ament, Fang Yang, Ying Liu, Michael J. Polydefkis, Luc Pellerin, Brett M. Morrison

Exp Neurol. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Exp Neurol. 2020 Nov; 333: 113415. Published online 2020 Jul 25. doi: 10.1016/j.expneurol.2020.113415

PMCID:: PMC7502508

Abstract Article PDF–1.0M

Select item 49438595.

Slc5a8, a Na⁺-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumor suppressor in colon that protects against colitis and colon cancer under low-fiber dietary conditions

Ashish Gurav, Sathish Sivaprakasam, Yangzom D. Bhutia, Thomas Boettger, Nagendra Singh, Vadivel Ganapathy

Biochem J. Author manuscript; available in PMC 2016 Jul 13.

Published in final edited form as: Biochem J. 2015 Jul 15; 469(2): 267–278. Published online 2015 May 18. doi: 10.1042/BJ20150242

PMCID:: PMC4943859

Abstract Article PDF–1.0M

Select item 49301566.

SLC transporters as a novel class of tumour suppressors: identity, function and molecular mechanisms

Yangzom D. Bhutia, Ellappan Babu, Sabarish Ramachandran, Shengping Yang, Muthusamy Thangaraju, Vadivel Ganapathy

Biochem J. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: Biochem J. 2016 May 1; 473(9): 1113–1124. doi: 10.1042/BJ20150751

PMCID:: PMC4930156

Abstract Article PDF–645K

Select item 38118687.

Molecular Mechanism of SLC5A8 Inactivation in Breast Cancer

Selvakumar Elangovan, Rajneesh Pathania, Sabarish Ramachandran, Sudha Ananth, Ravi N. Padia, Sonne R. Srinivas, Ellappan Babu, Lesleyann Hawthorn, Patricia V. Schoenlein, Thomas Boettger, Sylvia B. Smith, Puttur D. Prasad, Vadivel Ganapathy, Muthusamy Thangaraju

Mol Cell Biol. 2013 Oct; 33(19): 3920–3935. doi: 10.1128/MCB.01702-12

PMCID:: PMC3811868

Abstract Article PDF–3.6M

Select item 35724108.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 32598099.

Lactaturia and Loss of Sodium-dependent Lactate Uptake in the Colon of SLC5A8-deficient Mice

Henning Frank, Nicole Gröger, Martin Diener, Christoph Becker, Thomas Braun, Thomas Boettger

J Biol Chem. 2008 Sep 5; 283(36): 24729–24737. doi: 10.1074/jbc.M802681200

PMCID:: PMC3259809

Abstract Article PDF–559K

Select item 317805910.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 317607811.

Transport via SLC5A8 (SMCT1) Is Obligatory for 2-Oxothiazolidine-4-Carboxylate to Enhance Glutathione Production in Retinal Pigment Epithelial Cells

Ellappan Babu, Sudha Ananth, Rajalakshmi Veeranan-Karmegam, Veena Coothankandaswamy, Sylvia B. Smith, Thomas Boettger, Vadivel Ganapathy, Pamela M. Martin

Invest Ophthalmol Vis Sci. 2011 Jul; 52(8): 5749–5757. Published online 2011 Jul 27. doi: 10.1167/iovs.10-6825

PMCID:: PMC3176078

Abstract Article PDF–1.1M

Select item 302253412.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 295733513.

The probiotic Lactobacillus plantarum counteracts TNF-α-induced downregulation of SMCT1 expression and function

Alip Borthakur, Arivarasu N. Anbazhagan, Anoop Kumar, Geetu Raheja, Varsha Singh, Krishnamurthy Ramaswamy, Pradeep K. Dudeja

Am J Physiol Gastrointest Liver Physiol. 2010 Oct; 299(4): G928–G934. Published online 2010 Jul 29. doi: 10.1152/ajpgi.00279.2010

PMCID:: PMC2957335

Abstract Article

Select item 293462714.

Blockade of Dendritic Cell Development by Bacterial Fermentation Products Butyrate and Propionate through a Transporter (Slc5a8)-dependent Inhibition of Histone Deacetylases

Nagendra Singh, Muthusamy Thangaraju, Puttur D. Prasad, Pamela M. Martin, Nevin A. Lambert, Thomas Boettger, Stefan Offermanns, Vadivel Ganapathy

J Biol Chem. 2010 Sep 3; 285(36): 27601–27608. Published online 2010 Jul 2. doi: 10.1074/jbc.M110.102947

PMCID:: PMC2934627

Abstract Article PDF–1.7M

Select item 270348615.

Cloning and Functional Characterization of Human SMCT2 (SLC5A12) and Expression Pattern of the Transporter in Kidney

E. Gopal, N. S. Umapathy, P. M. Martin, S. Ananth, J. P. Gnana-Prakasam, H. Becker, C. A. Wagner, V. Ganapathy, P. D. Prasad

Biochim Biophys Acta. Author manuscript; available in PMC 2009 Jun 29.

Published in final edited form as: Biochim Biophys Acta. 2007 Nov; 1768(11): 2690–2697. Published online 2007 Jul 14. doi: 10.1016/j.bbamem.2007.06.031

PMCID:: PMC2703486

Abstract Article PDF–1.6M

Select item 141356816.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086

PMCID:: PMC1413568

Article PDF–99K

Select item 118672017.

Sodium-coupled and electrogenic transport of B-complex vitamin nicotinic acid by slc5a8, a member of the Na/glucose co-transporter gene family

Elangovan Gopal, You-Jun Fei, Seiji Miyauchi, Lina Zhuang, Puttur D. Prasad, Vadivel Ganapathy

Biochem J. 2005 May 15; 388(Pt 1): 309–316. Prepublished online 2005 Jan 14. Published online 2005 May 10. doi: 10.1042/BJ20041916

PMCID:: PMC1186720

Abstract Article PDF–146K

Select item 31099218.

RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki

Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600

PMCID:: PMC310992

Abstract Article PDF–3.4M

Select item 31098019.

Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes

Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki

Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100

PMCID:: PMC310980

Abstract Article PDF–1.4M

Select item 13924120.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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