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Items: 1 to 20 of 68

1.
Co-localization of the sodium-glucose co-transporter-2 channel (SGLT-2) with endothelin ETA and ETB receptors in human cardiorenal tissue
Thomas L. Williams, Rhoda E. Kuc, Anna L. Paterson, George R. Abraham, Anna L. Pullinger, Janet J. Maguire, Sanjay Sinha, Peter J. Greasley, Philip Ambery, Anthony P. Davenport
Biosci Rep. 2024 Jun 26; 44(6): BSR20240604. Published online 2024 May 31. doi: 10.1042/BSR20240604
PMCID:
PMC11147812
AbstractArticlePDF–3.6M
2.
Role and molecular mechanisms of SGLT2 inhibitors in pathological cardiac remodeling (Review)
Bixian Chen, Jing Guo, Hongmei Ye, Xinyu Wang, Yufei Feng
Mol Med Rep. 2024 May; 29(5): 73. Published online 2024 Mar 11. doi: 10.3892/mmr.2024.13197
PMCID:
PMC10955520
AbstractArticlePDF–2.1M
3.
Inhibition of Sodium-Glucose Cotransporter-2 during Serum Deprivation Increases Hepatic Gluconeogenesis via the AMPK/AKT/FOXO Signaling Pathway
Jinmi Lee, Seok-Woo Hong, Min-Jeong Kim, Yu-Mi Lim, Sun Joon Moon, Hyemi Kwon, Se Eun Park, Eun-Jung Rhee, Won-Young Lee
Endocrinol Metab (Seoul) 2024 Feb; 39(1): 98–108. Published online 2024 Jan 3. doi: 10.3803/EnM.2023.1786
PMCID:
PMC10901661
AbstractArticlePDF–2.0M
4.
Transport and inhibition mechanism of the human SGLT2–MAP17 glucose transporter
Masahiro Hiraizumi, Tomoya Akashi, Kouta Murasaki, Hiroyuki Kishida, Taichi Kumanomidou, Nao Torimoto, Osamu Nureki, Ikuko Miyaguchi
Nat Struct Mol Biol. 2024; 31(1): 159–169. Published online 2023 Dec 6. doi: 10.1038/s41594-023-01134-0
PMCID:
PMC10803289
AbstractArticlePDF–11M
5.
A Transcriptome Array-Based Approach to Link SGLT-2 and Intrarenal Complement C5 Synthesis in Diabetic Nephropathy
Peter Korsten, Björn Tampe
Int J Mol Sci. 2023 Dec; 24(23): 17066. Published online 2023 Dec 2. doi: 10.3390/ijms242317066
PMCID:
PMC10707485
AbstractArticlePDF–1.5M
6.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
7.
Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer susceptibility: an updated meta-analysis
Yuwei Wang, Lili Huo, Changqing Yang, Xiaofeng He
Biosci Rep. 2023 Apr 26; 43(4): BSR20222553. Published online 2023 Apr 19. doi: 10.1042/BSR20222553
PMCID:
PMC10116338
AbstractArticlePDF–1.8M
8.
Assessment of community efforts to advance network-based prediction of protein–protein interactions
Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu
Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7
PMCID:
PMC10033937
AbstractArticlePDF–1.5M
9.
The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain
Lisa Marie Weber, Yulin Jia, Bastian Stielow, Stephen S Gisselbrecht, Yinghua Cao, Yanpeng Ren, Iris Rohner, Jessica King, Elisabeth Rothman, Sabrina Fischer, Clara Simon, Ignasi Forné, Andrea Nist, Thorsten Stiewe, Martha L Bulyk, Zhanxin Wang, Robert Liefke
Nucleic Acids Res. 2023 Jan 25; 51(2): 574–594. Published online 2022 Dec 20. doi: 10.1093/nar/gkac1188
PMCID:
PMC9881136
AbstractArticlePDF–4.4M
10.
Decreased expression of Glucagon-like peptide-1 receptor and Sodium-glucose co-transporter 2 in patients with proliferative diabetic retinopathy
Hui Chen, Xiongze Zhang, Nanying Liao, Yuying Ji, Lan Mi, Yuhong Gan, Yongyue Su, Feng Wen
Front Endocrinol (Lausanne) 2022; 13: 1020252. Published online 2022 Nov 17. doi: 10.3389/fendo.2022.1020252
PMCID:
PMC9712753
AbstractArticlePDF–5.6M
11.
Hepatic expression of sodium–glucose cotransporter 2 (SGLT2) in patients with chronic liver disease
Dan Nakano, Jun Akiba, Tsubasa Tsutsumi, Machiko Kawaguchi, Takafumi Yoshida, Hironori Koga, Takumi Kawaguchi
Med Mol Morphol. 2022; 55(4): 304–315. Published online 2022 Sep 21. doi: 10.1007/s00795-022-00334-9
PMCID:
PMC9606064
AbstractArticlePDF–1.1M
12.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
13.
circ_000166/miR-296 Aggravates the Process of Diabetic Renal Fibrosis by Regulating the SGLT2 Signaling Pathway in Renal Tubular Epithelial Cells
Sheng Chen
Dis Markers. 2022; 2022: 6103086. Published online 2022 May 16. doi: 10.1155/2022/6103086
PMCID:
PMC9126678
AbstractArticlePDF–2.3M
14.
Effects of Sodium-Glucose Cotransporter 2 on Amputation Events: A Systematic Review and Meta-Analysis of Randomized-Controlled Trials
Ray Meng See, Yao Neng Teo, Yao Hao Teo, Nicholas L. Syn, Alicia Swee Yan Yip, Shariel Leong, Caitlin Fern Wee, Alex Jia Yang Cheong, Chi-Hang Lee, Mark Yan-Yee Chan, Tiong Cheng Yeo, Raymond C.C. Wong, Peter Chang, Choon Chiet Hong, Ping Chai, Ching-Hui Sia
Pharmacology. 2022 Mar; 107(3-4): 123–130. Published online 2021 Dec 23. doi: 10.1159/000520903
PMCID:
PMC8985006
AbstractArticle
15.
An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity
Yuehui Zhang, Limin Shang, Jing Zhang, Yuchen Liu, Chaozhi Jin, Yanan Zhao, Xiaobo Lei, Wenjing Wang, Xia Xiao, Xiuyuan Zhang, Yujiao Liu, Linlin Liu, Meng-Wei Zhuang, Qingkun Mi, Chunyan Tian, Jianwei Wang, Fuchu He, Pei-Hui Wang, Jian Wang
Cell Chem Biol. 2022 Jan 20; 29(1): 5–18.e6. Published online 2021 Oct 20. doi: 10.1016/j.chembiol.2021.10.008
PMCID:
PMC8527578
AbstractArticlePDF–4.5M
16.
Treatment Response to SGLT2 Inhibitors: From Clinical Characteristics to Genetic Variations
Jasna Klen, Vita Dolžan
Int J Mol Sci. 2021 Sep; 22(18): 9800. Published online 2021 Sep 10. doi: 10.3390/ijms22189800
PMCID:
PMC8466905
AbstractArticlePDF–533K
17.
Exploring the Pleiotropic Genes and Therapeutic Targets Associated with Heart Failure and Chronic Kidney Disease by Integrating metaCCA and SGLT2 Inhibitors' Target Prediction
Huanqiang Li, Ziling Mai, Sijia Yu, Bo Wang, Wenguang Lai, Guanzhong Chen, Chunyun Zhou, Jin Liu, Yongquan Yang, Shiqun Chen, Yong Liu, Jiyan Chen
Biomed Res Int. 2021; 2021: 4229194. Published online 2021 Sep 8. doi: 10.1155/2021/4229194
PMCID:
PMC8443964
AbstractArticlePDF–1.1M
18.
Cardioprotection by SGLT2 Inhibitors—Does It All Come Down to Na+?
Maximilian Trum, Johannes Riechel, Stefan Wagner
Int J Mol Sci. 2021 Aug; 22(15): 7976. Published online 2021 Jul 26. doi: 10.3390/ijms22157976
PMCID:
PMC8347698
AbstractArticlePDF–2.2M
19.
Effects of SGLT2 inhibitors on stroke and its subtypes in patients with type 2 diabetes: a systematic review and meta-analysis
Wen-Hsuan Tsai, Shih-Ming Chuang, Sung-Chen Liu, Chun-Chuan Lee, Ming-Nan Chien, Ching-Hsiang Leung, Shu-Jung Liu, Hong-Mou Shih
Sci Rep. 2021; 11: 15364. Published online 2021 Jul 28. doi: 10.1038/s41598-021-94945-4
PMCID:
PMC8319393
AbstractArticlePDF–1.4M
20.
Sodium Glucose Co-Transporter 2 Inhibitors Ameliorate Endothelium Barrier Dysfunction Induced by Cyclic Stretch through Inhibition of Reactive Oxygen Species
Xiaoling Li, Gregor Römer, Raphaela P. Kerindongo, Jeroen Hermanides, Martin Albrecht, Markus W. Hollmann, Coert J. Zuurbier, Benedikt Preckel, Nina C. Weber
Int J Mol Sci. 2021 Jun; 22(11): 6044. Published online 2021 Jun 3. doi: 10.3390/ijms22116044
PMCID:
PMC8199893
AbstractArticlePDF–1.7M

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