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Select item 109982321.

MAPK15 controls cellular responses to oxidative stress by regulating NRF2 activity and expression of its downstream target genes

Lorenzo Franci, Giulia Vallini, Franca Maria Bertolino, Vittoria Cicaloni, Giovanni Inzalaco, Mattia Cicogni, Laura Tinti, Laura Calabrese, Virginia Barone, Laura Salvini, Pietro Rubegni, Federico Galvagni, Mario Chiariello

Redox Biol. 2024 Jun; 72: 103131. Published online 2024 Mar 28. doi: 10.1016/j.redox.2024.103131

PMCID:: PMC10998232

Abstract Article PDF–11M

Select item 107787002.

Mitogen-Activated Protein Kinase 15 Is a New Predictive Biomarker and Potential Therapeutic Target for Ovarian Cancer

Qiu-Hua Zhong, Andy T. Y. Lau, Yan-Ming Xu

Int J Mol Sci. 2024 Jan; 25(1): 109. Published online 2023 Dec 20. doi: 10.3390/ijms25010109

PMCID:: PMC10778700

Abstract Article PDF–1.6M

Select item 100729063.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 92828344.

MAPK15 protects from oxidative stress‐dependent cellular senescence by inducing the mitophagic process

Lorenzo Franci, Alessandro Tubita, Franca Maria Bertolino, Alessandro Palma, Giuseppe Cannino, Carmine Settembre, Andrea Rasola, Elisabetta Rovida, Mario Chiariello

Aging Cell. 2022 Jul; 21(7): e13620. Published online 2022 Jun 1. doi: 10.1111/acel.13620

PMCID:: PMC9282834

Abstract Article PDF–4.8M

Select item 92792855.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 88970226.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 74273278.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 73220679.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 658119710.

Gain of additional BIRC3 protein functions through 3′UTR-mediated protein complex formation

Shih-Han Lee, Christine Mayr

Mol Cell. Author manuscript; available in PMC 2020 May 16.

Published in final edited form as: Mol Cell. 2019 May 16; 74(4): 701–712.e9. Published online 2019 Apr 1. doi: 10.1016/j.molcel.2019.03.006

PMCID:: PMC6581197

Abstract Article PDF–2.0M

Select item 618762511.

MAPK15 is part of the ULK complex and controls its activity to regulate early phases of the autophagic process

David Colecchia, Francesca Dapporto, Serena Tronnolone, Laura Salvini, Mario Chiariello

J Biol Chem. 2018 Oct 12; 293(41): 15962–15976. Published online 2018 Aug 21. doi: 10.1074/jbc.RA118.002527

PMCID:: PMC6187625

Abstract Article PDF–4.8M

Select item 571445712.

Primary Cilium Formation and Ciliary Protein Trafficking Is Regulated by the Atypical MAP Kinase MAPK15 in Caenorhabditis elegans and Human Cells

Anna Kazatskaya, Stefanie Kuhns, Nils J. Lambacher, Julie E. Kennedy, Andrea G. Brear, Gavin J. McManus, Piali Sengupta, Oliver E. Blacque

Genetics. 2017 Dec; 207(4): 1423–1440. Published online 2017 Oct 10. doi: 10.1534/genetics.117.300383

PMCID:: PMC5714457

Abstract Article PDF–3.0M

Select item 566346513.

A Global Analysis of The Receptor Tyrosine Kinase – Protein Phosphatase Interactome

Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar

Mol Cell. Author manuscript; available in PMC 2017 Oct 31.

Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 347–360. Published online 2017 Jan 5. doi: 10.1016/j.molcel.2016.12.004

PMCID:: PMC5663465

Abstract Article PDF–2.1M

Select item 560747014.

The Atypical MAP Kinase SWIP-13/ERK8 Regulates Dopamine Transporters through a Rho-Dependent Mechanism

Daniel P. Bermingham, J. Andrew Hardaway, Osama Refai, Christian R. Marks, Sam L. Snider, Sarah M. Sturgeon, William C. Spencer, Roger J. Colbran, David M. Miller, III, Randy D. Blakely

J Neurosci. 2017 Sep 20; 37(38): 9288–9304. doi: 10.1523/JNEUROSCI.1582-17.2017

PMCID:: PMC5607470

Abstract Article PDF–4.0M

Select item 553161115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 499150616.

MAPK15 upregulation promotes cell proliferation and prevents DNA damage in male germ cell tumors

Matteo Rossi, David Colecchia, Gennaro Ilardi, Mario Acunzo, Giovanni Nigita, Federica Sasdelli, Angela Celetti, Angela Strambi, Stefania Staibano, Carlo Maria Croce, Mario Chiariello

Oncotarget. 2016 Apr 12; 7(15): 20981–20998. Published online 2016 Mar 14. doi: 10.18632/oncotarget.8044

PMCID:: PMC4991506

Abstract Article PDF–9.0M

Select item 482457217.

MAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation

David Colecchia, Matteo Rossi, Federica Sasdelli, Sveva Sanzone, Angela Strambi, Mario Chiariello

Autophagy. 2015 Oct; 11(10): 1790–1802. Published online 2015 Aug 20. doi: 10.1080/15548627.2015.1084454

PMCID:: PMC4824572

Abstract Article PDF–1.3M

Select item 481147118.

ERK8 is a novel HuR kinase that regulates tumour suppressor PDCD4 through a miR-21 dependent mechanism

Urszula Liwak-Muir, Christine C. Dobson, Thet Naing, Quinlan Wylie, Lucia Chehade, Stephen D. Baird, Pranesh K. Chakraborty, Martin Holcik

Oncotarget. 2016 Jan 12; 7(2): 1439–1450. Published online 2015 Nov 22. doi: 10.18632/oncotarget.6363

PMCID:: PMC4811471

Abstract Article PDF–2.9M

Select item 465299719.

Overexpression of MAPK15 in gastric cancer is associated with copy number gain and contributes to the stability of c-Jun

Dong-Hao Jin, Jeeyun Lee, Kyoung Mee Kim, Sung Kim, Duk-Hwan Kim, Joobae Park

Oncotarget. 2015 Aug 21; 6(24): 20190–20203. Published online 2015 May 19. doi: 10.18632/oncotarget.4171

PMCID:: PMC4652997

Abstract Article PDF–2.8M

Select item 461721120.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

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