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Items: 1 to 20 of 29

1.
CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1
Dongbao Li, Yuhong Wang, Chao Dong, Tao Chen, Anqi Dong, Jiayu Ren, Weikang Li, Gege Shu, Jiaoyang Yang, Wenhao Shen, Lei Qin, Lin Hu, Jin Zhou
Oncogene. 2023; 42(2): 83–98. Published online 2022 Nov 12. doi: 10.1038/s41388-022-02537-x
PMCID:
PMC9816059
AbstractArticlePDF–7.6M
2.
Troy/Tnfrsf19 marks epidermal cells that govern interfollicular epidermal renewal and cornification
Kai Kretzschmar, Kim E. Boonekamp, Margit Bleijs, Priyanca Asra, Mandy Koomen, Susana M. Chuva de Sousa Lopes, Barbara Giovannone, Hans Clevers
Stem Cell Reports. 2021 Sep 14; 16(9): 2379–2394. Published online 2021 Aug 5. doi: 10.1016/j.stemcr.2021.07.007
PMCID:
PMC8452520
AbstractArticlePDF–4.3M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
TROY signals through JAK1-STAT3 to promote glioblastoma cell migration and resistance
Zonghui Ding, Jean M. Kloss, Serdar Tuncali, Nhan L. Tran, Joseph C. Loftus
Neoplasia. 2020 Sep; 22(9): 352–364. Published online 2020 Jul 3. doi: 10.1016/j.neo.2020.06.005
PMCID:
PMC7338993
AbstractArticlePDF–2.1M
5.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
6.
A Four-gene Transcript Score to Predict Metastatic-lethal Progression in Men Treated for Localized Prostate Cancer: Development and Validation Studies
Anqi Cheng, Shanshan Zhao, Liesel M. FitzGerald, Jonathan L. Wright, Suzanne Kolb, R. Jeffrey Karnes, Robert B. Jenkins, Elai Davicioni, Elaine A. Ostrander, Ziding Feng, Jian-Bing Fan, James Y. Dai, Janet L. Stanford
Prostate. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: Prostate. 2019 Oct; 79(14): 1589–1596. Published online 2019 Aug 2. doi: 10.1002/pros.23882
PMCID:
PMC6715522
AbstractArticlePDF–558K
7.
Immunohistochemical Analysis of LGR5 and TROY Expression in Gastric Carcinogenesis Demonstrates an Inverse Trend
Samaneh Saberi, Abbas Piryaei, Esmat Mirabzadeh, Maryam Esmaeili, Toktam Karimi, Sara Momtaz, Afshin Abdirad, Niloofar Sodeifi, Mohammad Ali Mohagheghi, Hossein Baharvand, Marjan Mohammadi
Iran Biomed J. 2019 Mar; 23(2): 107–120. doi: 10.29252/.23.2.107
PMCID:
PMC6707110
AbstractArticlePDF–1.8M
8.
The inherited variations of a p53-responsive enhancer in 13q12.12 confer lung cancer risk by attenuating TNFRSF19 expression
Lipei Shao, Xianglin Zuo, Yin Yang, Yu Zhang, Nan Yang, Bin Shen, Jianying Wang, Xuchun Wang, Ruilei Li, Guangfu Jin, Dawei Yu, Yuan Chen, Luan Sun, Zhen Li, Qiaofen Fu, Zhibin Hu, Xiao Han, Xin Song, Hongbin Shen, Yujie Sun
Genome Biol. 2019; 20: 103. Published online 2019 May 24. doi: 10.1186/s13059-019-1696-1
PMCID:
PMC6533720
AbstractArticlePDF–5.6M
9.
TROY interacts with RKIP to promote glioma development
Xiujie Liu, Yinghui Bao, Wei Meng, Ping Yang, Yi An, Jie Ma, Yujie Tang, Zhigang Liu, Yan Lu, Jianfeng Zhou, Yong Zhang, Jifeng Feng, Xiaofei Gao, Zhida Su, Yingyan Pu, Cheng He
Oncogene. 2019; 38(9): 1544–1559. Published online 2018 Oct 18. doi: 10.1038/s41388-018-0503-x
PMCID:
PMC6372479
AbstractArticlePDF–6.5M
10.
PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival
Zonghui Ding, Harshil Dhruv, Aneta Kwiatkowska-Piwowarczyk, Rosamaria Ruggieri, Jean Kloss, Marc Symons, Patrick Pirrotte, Jennifer M. Eschbacher, Nhan L. Tran, Joseph C. Loftus
Neoplasia. 2018 Oct; 20(10): 1045–1058. Published online 2018 Sep 13. doi: 10.1016/j.neo.2018.08.008
PMCID:
PMC6140379
AbstractArticlePDF–999K
11.
Novel Signaling Complex Between TROY and EGFR Mediates Glioblastoma Cell Invasion
Zonghui Ding, Alison Roos, Jean Kloss, Harshil Dhruv, Sen Peng, Patrick Pirrotte, Jennifer M. Eschbacher, Nhan L. Tran, Joseph C. Loftus
Mol Cancer Res. Author manuscript; available in PMC 2019 Feb 1.
Published in final edited form as: Mol Cancer Res. 2018 Feb; 16(2): 322–332. Published online 2017 Nov 8. doi: 10.1158/1541-7786.MCR-17-0454
PMCID:
PMC5805628
AbstractArticlePDF–1.0M
12.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
13.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
14.
Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint
Melanie L. Bailey, Tejomayee Singh, Patricia Mero, Jason Moffat, Philip Hieter
Genetics. 2015 Nov; 201(3): 885–895. Published online 2015 Sep 8. doi: 10.1534/genetics.115.180653
PMCID:
PMC4649658
AbstractArticlePDF–1.8M
15.
Gene–Smoking Interactions Identify Several Novel Blood Pressure Loci in the Framingham Heart Study
Yun J. Sung, Lisa de las Fuentes, Karen L. Schwander, Jeannette Simino, Dabeeru C. Rao
Am J Hypertens. 2015 Mar; 28(3): 343–354. Published online 2014 Sep 3. doi: 10.1093/ajh/hpu149
PMCID:
PMC4402348
AbstractArticlePDF–38M
16.
New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing
Fernanda Luisa Basei, Gabriela Vaz Meirelles, Germanna Lima Righetto, Deivid Lucas dos Santos Migueleti, Juliana Helena Costa Smetana, Jörg Kobarg
Proteome Sci. 2015; 13: 11. Published online 2015 Feb 26. doi: 10.1186/s12953-015-0065-6
PMCID:
PMC4367857
AbstractArticlePDF–3.1M
17.
TROY Interacts with Rho Guanine Nucleotide Dissociation Inhibitor α (RhoGDIα) to Mediate Nogo-induced Inhibition of Neurite Outgrowth
Yan Lu, Xiujie Liu, Jianfeng Zhou, Aijun Huang, Jiazhen Zhou, Cheng He
J Biol Chem. 2013 Nov 22; 288(47): 34276–34286. Published online 2013 Oct 15. doi: 10.1074/jbc.M113.519744
PMCID:
PMC3837168
AbstractArticlePDF–2.5M
18.
TROY (TNFRSF19) promotes glioblastoma cell survival signaling and therapeutic resistance
Joseph C. Loftus, Harshil Dhruv, Serdar Tuncali, Jean Kloss, Zhongbo Yang, Cassie A. Schumacher, Brian Cao, Bart O. Williams, Jennifer M. Eschbacher, Julianna T.D. Ross, Nhan L. Tran
Mol Cancer Res. Author manuscript; available in PMC 2014 Aug 1.
Published in final edited form as: Mol Cancer Res. 2013 Aug; 11(8): 865–874. Published online 2013 May 22. doi: 10.1158/1541-7786.MCR-13-0008
PMCID:
PMC3748253
AbstractArticlePDF–1.1M
19.
Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women
Caroline S. Fox, Yongmei Liu, Charles C. White, Mary Feitosa, Albert V. Smith, Nancy Heard-Costa, Kurt Lohman, GIANT Consortium, MAGIC Consortium, GLGC Consortium, Andrew D. Johnson, Meredith C. Foster, Danielle M. Greenawalt, Paula Griffin, Jinghong Ding, Anne B. Newman, Fran Tylavsky, Iva Miljkovic, Stephen B. Kritchevsky, Lenore Launer, Melissa Garcia, Gudny Eiriksdottir, J. Jeffrey Carr, Vilmunder Gudnason, Tamara B. Harris, L. Adrienne Cupples, Ingrid B. Borecki
PLoS Genet. 2012 May; 8(5): e1002695. Published online 2012 May 10. doi: 10.1371/journal.pgen.1002695
PMCID:
PMC3349734
AbstractArticlePDF–377K
20.
Novel Associations for Hypothyroidism Include Known Autoimmune Risk Loci
Nicholas Eriksson, Joyce Y. Tung, Amy K. Kiefer, David A. Hinds, Uta Francke, Joanna L. Mountain, Chuong B. Do
PLoS One. 2012; 7(4): e34442. Published online 2012 Apr 6. doi: 10.1371/journal.pone.0034442
PMCID:
PMC3321023
AbstractArticlePDF–750K

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