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Select item 109696301.

UROMODULIN – A LINK BETWEEN SODIUM EXCRETION AND ALTERATION IN CIRCADIAN BLOOD PRESSURE PATTERN IN PREHYPERTENSIVES

Josipa Josipović, Livija Šimičević, Živka Dika, Nikola Bulj, Mislav Vrsalović, Bojan Jelaković

Acta Clin Croat. 2023 Aug; 62(2): 313–322. Published online 2023 Aug. doi: 10.20471/acc.2023.62.02.09

PMCID:: PMC10969630

Abstract Article PDF–376K

Select item 108246552.

The Versatile Role of Uromodulin in Renal Homeostasis and Its Relevance in Chronic Kidney Disease

Tomoaki Takata, Hajime Isomoto

Intern Med. 2024 Jan 1; 63(1): 17–23. Published online 2023 Jan 15. doi: 10.2169/internalmedicine.1342-22

PMCID:: PMC10824655

Abstract Article PDF–596K

Select item 105472243.

Healthy Women Have Higher Systemic Uromodulin Levels: Identification of Uromodulin as an Estrogen Responsive Gene

Azuma Nanamatsu, Radmila Micanovic, Shehnaz Khan, Tarek M. El-Achkar, Kaice A. LaFavers

Kidney360. 2023 Sep; 4(9): e1302–e1307. Published online 2023 Jun 21. doi: 10.34067/KID.0000000000000197

PMCID:: PMC10547224

Abstract Article PDF–758K

Select item 104033504.

Longitudinal effects of a common UMOD variant on kidney function, blood pressure, cognitive and physical function in older women and men

Engi Abdel–Hady Algharably, Linda Elizabeth Villagomez Fuentes, Sarah Toepfer, Maximilian König, Vera Regitz-Zagrosek, Lars Bertram, Juliane Bolbrinker, Ilja Demuth, Reinhold Kreutz

J Hum Hypertens. 2023; 37(8): 709–717. Published online 2022 Nov 28. doi: 10.1038/s41371-022-00781-y

PMCID:: PMC10403350

Abstract Article PDF–865K

Select item 100864945.

A founder UMOD variant is a common cause of hereditary nephropathy in the British population

Manoj K Valluru, Noelle KX Chung, Mark Gilchrist, Laura Butland, Jackie Cook, Anna Takou, Abhijit Dixit, Michael N Weedon, Albert C M Ong, The Genomics England Research Consortium

J Med Genet. 2023 Apr; 60(4): 397–405. Published online 2022 Aug 29. doi: 10.1136/jmg-2022-108704

PMCID:: PMC10086494

Abstract Article PDF–3.8M

Select item 96494236.

Effect of a common UMOD variant on kidney function, blood pressure, cognitive and physical function in a community-based cohort of older adults

Linda Elizabeth Villagomez Fuentes, Engi Abdel–Hady Algharably, Sarah Toepfer, Maximilian König, Ilja Demuth, Lars Bertram, Reinhold Kreutz, Juliane Bolbrinker

J Hum Hypertens. 2022; 36(11): 983–988. Published online 2021 Sep 30. doi: 10.1038/s41371-021-00608-2

PMCID:: PMC9649423

Abstract Article PDF–557K

Select item 93881137.

An intermediate-effect size variant in UMOD confers risk for chronic kidney disease

Eric Olinger, Céline Schaeffer, Kendrah Kidd, Elhussein A. E. Elhassan, Yurong Cheng, Inès Dufour, Guglielmo Schiano, Holly Mabillard, Elena Pasqualetto, Patrick Hofmann, Daniel G. Fuster, Andreas D. Kistler, Ian J. Wilson, Stanislav Kmoch, Laure Raymond, Thomas Robert, Genomics England Research Consortium, Kai-Uwe Eckardt, Anthony J. Bleyer, Sr., Anna Köttgen, Peter J. Conlon, Michael Wiesener, John A. Sayer, Luca Rampoldi, Olivier Devuyst

Proc Natl Acad Sci U S A. 2022 Aug 16; 119(33): e2114734119. Published online 2022 Aug 10. doi: 10.1073/pnas.2114734119

PMCID:: PMC9388113

Abstract Article PDF–1.8M

Select item 89307698.

Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH

Alena Stsiapanava, Chenrui Xu, Shunsuke Nishio, Ling Han, Nao Yamakawa, Marta Carroni, Kathryn Tunyasuvunakool, John Jumper, Daniele de Sanctis, Bin Wu, Luca Jovine

Nat Struct Mol Biol. 2022; 29(3): 190–193. Published online 2022 Mar 10. doi: 10.1038/s41594-022-00729-3

PMCID:: PMC8930769

Abstract Article PDF–5.3M

Select item 88057369.

A Lower Ratio of Uromodulin to Osteopontin in Deceased Donor Urine is Associated with Favorable Kidney Graft Outcomes

Sherry G. Mansour, Caroline Liu, Yaqi Jia, Peter P. Reese, Isaac E. Hall, Tarek M. El-Achkar, Kaice A. LaFavers, Wassim Obeid, Joe M. El-Khoury, Avi Z. Rosenberg, Parnaz Daneshpajouhnejad, Mona D. Doshi, Enver Akalin, Jonathan S. Bromberg, Meera N. Harhay, Sumit Mohan, Thangamani Muthukumar, Bernd Schröppel, Pooja Singh, Francis L. Weng, Heather R. Thiessen-Philbrook, Chirag R. Parikh

Transplantation. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: Transplantation. 2021 Apr 1; 105(4): 876–885. doi: 10.1097/TP.0000000000003299

PMCID:: PMC8805736

Abstract Article PDF–682K

Select item 862061610.

UMOD Polymorphisms Associated with Kidney Function, Serum Uromodulin and Risk of Mortality among Patients with Chronic Kidney Disease, Results from the C-STRIDE Study

Jinwei Wang, Lili Liu, Kevin He, Bixia Gao, Fang Wang, Minghui Zhao, Luxia Zhang, on behalf of the Chinese Cohort Study of Chronic Kidney Disease (C-STRIDE)

Genes (Basel) 2021 Nov; 12(11): 1687. Published online 2021 Oct 23. doi: 10.3390/genes12111687

PMCID:: PMC8620616

Abstract Article PDF–983K

Select item 822867211.

Polymorphism in the GATM Locus Associated with Dialysis-Independent Chronic Kidney Disease but Not Dialysis-Dependent Kidney Failure

Špela Šalamon, Sebastjan Bevc, Robert Ekart, Radovan Hojs, Uroš Potočnik

Genes (Basel) 2021 Jun; 12(6): 834. Published online 2021 May 28. doi: 10.3390/genes12060834

PMCID:: PMC8228672

Abstract Article PDF–271K

Select item 796225212.

The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex

Xin Wang, Wei Jiang, Shuo Luo, Xiaoyu Yang, Changnan Wang, Bingying Wang, Yongjun Dang, Yin Shen, Dengke K. Ma

Mol Brain. 2021; 14: 54. Published online 2021 Mar 16. doi: 10.1186/s13041-021-00767-w

PMCID:: PMC7962252

Abstract Article PDF–6.5M

Select item 778339513.

Extratubular Polymerized Uromodulin Induces Leukocyte Recruitment and Inflammation In Vivo

Roland Immler, Bärbel Lange-Sperandio, Tobias Steffen, Heike Beck, Ina Rohwedder, Jonas Roth, Matteo Napoli, Georg Hupel, Frederik Pfister, Bastian Popper, Bernd Uhl, Hanna Mannell, Christoph A. Reichel, Volker Vielhauer, Jürgen Scherberich, Markus Sperandio, Monika Pruenster

Front Immunol. 2020; 11: 588245. Published online 2020 Dec 22. doi: 10.3389/fimmu.2020.588245

PMCID:: PMC7783395

Abstract Article PDF–9.7M

Select item 773761914.

Cryo‐EM structure of native human uromodulin, a zona pellucida module polymer

Alena Stsiapanava, Chenrui Xu, Martina Brunati, Sara Zamora‐Caballero, Céline Schaeffer, Marcel Bokhove, Ling Han, Hans Hebert, Marta Carroni, Shigeki Yasumasu, Luca Rampoldi, Bin Wu, Luca Jovine

EMBO J. 2020 Dec 15; 39(24): e106807. Published online 2020 Nov 16. doi: 10.15252/embj.2020106807

PMCID:: PMC7737619

Abstract Article PDF–4.6M

Select item 761111015.

Mechanistic Interactions of Uromodulin with the Thick Ascending Limb: Perspectives in Physiology and Hypertension

Philipp Boder, Sheon Mary, Patrick B. Mark, James Leiper, Anna F. Dominiczak, Sandosh Padmanabhan, Luca Rampoldi, Christian Delles

J Hypertens. Author manuscript; available in PMC 2021 Aug 1.

Published in final edited form as: J Hypertens. 2021 Aug 1; 39(8): 1490–1504. doi: 10.1097/HJH.0000000000002861

PMCID:: PMC7611110

Abstract Article PDF–1.2M

Select item 748612416.

The cryo-EM structure of the human uromodulin filament core reveals a unique assembly mechanism

Jessica J Stanisich, Dawid S Zyla, Pavel Afanasyev, Jingwei Xu, Anne Kipp, Eric Olinger, Olivier Devuyst, Martin Pilhofer, Daniel Boehringer, Rudi Glockshuber

eLife. 2020; 9: e60265. Published online 2020 Aug 20. doi: 10.7554/eLife.60265

PMCID:: PMC7486124

Abstract Article PDF–2.5M

Select item 746272417.

Association of serum uromodulin with mortality and cardiovascular disease in the elderly—the Cardiovascular Health Study

Dominik Steubl, Petra Buzkova, Pranav S Garimella, Joachim H Ix, Prasad Devarajan, Michael R Bennett, Paulo H M Chaves, Michael G Shlipak, Nisha Bansal, Mark J Sarnak

Nephrol Dial Transplant. 2020 Aug; 35(8): 1399–1405. Published online 2019 Mar 21. doi: 10.1093/ndt/gfz008

PMCID:: PMC7462724

Abstract Article PDF–279K

Select item 744906718.

A novel likely pathogenic variant in the UMOD gene in a family with autosomal dominant tubulointerstitial kidney disease: a case report

Ying Wang, Haibo Liu, Qingnan He, Zhuwen Yi, Yongzhen Li, Xiqiang Dang

BMC Nephrol. 2020; 21: 368. Published online 2020 Aug 26. doi: 10.1186/s12882-020-02022-1

PMCID:: PMC7449067

Abstract Article PDF–1.0M

Select item 741354119.

Serum uromodulin is inversely associated with arterial hypertension and the vasoconstrictive prohormone CT-proET-1 in the population-based KORA F4 study

Cornelia Then, Barbara Thorand, Holger L. Then, Christa Meisinger, Margit Heier, Annette Peters, Wolfgang Koenig, Wolfgang Rathmann, Martin Bidlingmaier, Andreas Lechner, Martin Reincke, Jürgen E. Scherberich, Jochen Seissler

PLoS One. 2020; 15(8): e0237364. Published online 2020 Aug 7. doi: 10.1371/journal.pone.0237364

PMCID:: PMC7413541

Abstract Article PDF–455K

Select item 729829820.

BGL3 lncRNA mediates retention of the BRCA1/BARD1 complex at DNA damage sites

Zhaohua Hu, Shaojie Mi, Ting Zhao, Changmin Peng, Yihan Peng, Lulu Chen, Wenge Zhu, Yi Yao, Qibin Song, Xiangpan Li, Xinzhi Li, Chenxi Jia, Huadong Pei

EMBO J. 2020 Jun 17; 39(12): e104133. Published online 2020 Apr 29. doi: 10.15252/embj.2019104133

PMCID:: PMC7298298

Abstract Article PDF–1.5M

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