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Select item 111941101.

Single-molecule imaging reveals a direct role of CTCF’s zinc fingers in SA interaction and cluster-dependent RNA recruitment

Jonas Huber, Nicoleta-Loredana Tanasie, Sarah Zernia, Johannes Stigler

Nucleic Acids Res. 2024 Jun 24; 52(11): 6490–6506. Published online 2024 May 14. doi: 10.1093/nar/gkae391

PMCID:: PMC11194110

Abstract Article PDF–2.1M

Select item 105658762.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 102374223.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 100062244.

Different NIPBL requirements of cohesin-STAG1 and cohesin-STAG2

Dácil Alonso-Gil, Ana Cuadrado, Daniel Giménez-Llorente, Miriam Rodríguez-Corsino, Ana Losada

Nat Commun. 2023; 14: 1326. Published online 2023 Mar 10. doi: 10.1038/s41467-023-36900-7

PMCID:: PMC10006224

Abstract Article PDF–2.7M

Select item 99786355.

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons

Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson

J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888

PMCID:: PMC9978635

Abstract Article PDF–10M

Select item 95403456.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 93485767.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 92792858.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 91631739.

Potential role of STAG1 mutations in genetic predisposition to childhood hematological malignancies

Claudia Saitta, Stefano Rebellato, Laura Rachele Bettini, Giovanni Giudici, Nicolò Panini, Eugenio Erba, Valentina Massa, Franziska Auer, Ulrike Friedrich, Julia Hauer, Andrea Biondi, Grazia Fazio, Giovanni Cazzaniga

Blood Cancer J. 2022 Jun; 12(6): 88. Published online 2022 Jun 2. doi: 10.1038/s41408-022-00683-9

PMCID:: PMC9163173

Article PDF–955K

Select item 911973610.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 874895811.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 856534712.

STAG2 loss-of-function affects short-range genomic contacts and modulates the basal-luminal transcriptional program of bladder cancer cells

Laia Richart, Eleonora Lapi, Vera Pancaldi, Mirabai Cuenca-Ardura, Enrique Carrillo-de-Santa Pau, Miguel Madrid-Mencía, Hélène Neyret-Kahn, François Radvanyi, Juan Antonio Rodríguez, Yasmina Cuartero, François Serra, François Le Dily, Alfonso Valencia, Marc A Marti-Renom, Francisco X Real

Nucleic Acids Res. 2021 Nov 8; 49(19): 11005–11021. Published online 2021 Oct 14. doi: 10.1093/nar/gkab864

PMCID:: PMC8565347

Abstract Article PDF–8.4M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 810809314.

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary

Cell. Author manuscript; available in PMC 2021 May 10.

Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050

PMCID:: PMC8108093

Abstract Article PDF–3.5M

Select item 794842515.

USP13 interacts with cohesin and regulates its ubiquitination in human cells

Xiaoyuan He, Jung-Sik Kim, Laura A. Diaz-Martinez, Cecil Han, William S. Lane, Bogdan Budnik, Todd Waldman

J Biol Chem. 2021 Jan-Jun; 296: 100194. Published online 2020 Dec 20. doi: 10.1074/jbc.RA120.015762

PMCID:: PMC7948425

Abstract Article PDF–1.2M

Select item 790491316.

PD-L1 regulates genomic stability via interaction with cohesin-SA1 in the nucleus

Wen Zhang, Jiali Jin, Yanjin Wang, Lan Fang, Liu Min, Xinbo Wang, Lin Ding, Linjun Weng, Tan Xiao, Tianhua Zhou, Ping Wang

Signal Transduct Target Ther. 2021; 6: 81. Published online 2021 Feb 25. doi: 10.1038/s41392-021-00463-0

PMCID:: PMC7904913

Article PDF–1.4M

Select item 726699317.

STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers

Petra van der Lelij, Joseph A Newman, Simone Lieb, Julian Jude, Vittorio Katis, Thomas Hoffmann, Matthias Hinterndorfer, Gerd Bader, Norbert Kraut, Mark A Pearson, Jan-Michael Peters, Johannes Zuber, Opher Gileadi, Mark Petronczki

Life Sci Alliance. 2020 Jul; 3(7): e202000725. Published online 2020 May 28. doi: 10.26508/lsa.202000725

PMCID:: PMC7266993

Abstract Article PDF–2.7M

Select item 688117118.

A conserved ATP- and Scc2/4-dependent activity for cohesin in tethering DNA molecules

Pilar Gutierrez-Escribano, Matthew D. Newton, Aida Llauró, Jonas Huber, Loredana Tanasie, Joseph Davy, Isabel Aly, Ricardo Aramayo, Alex Montoya, Holger Kramer, Johannes Stigler, David S. Rueda, Luis Aragon

Sci Adv. 2019 Nov; 5(11): eaay6804. Published online 2019 Nov 27. doi: 10.1126/sciadv.aay6804

PMCID:: PMC6881171

Abstract Article PDF–3.4M

Select item 684243819.

Cohesin members Stag1 and Stag2 display distinct roles in chromatin accessibility and topological control of HSC self-renewal and differentiation

Aaron D. Viny, Robert L. Bowman, Yu Liu, Vincent-Philippe Lavallée, Shira E. Eisman, Wenbin Xiao, Benjamin H. Durham, Anastasia Navitski, Jane Park, Stephanie Braunstein, Besmira Alija, Abdul Karzai, Isabelle S. Csete, Matthew Witkin, Elham Azizi, Timour Baslan, Christopher J. Ott, Dana Pe’er, Job Dekker, Richard Koche, Ross L. Levine

Cell Stem Cell. Author manuscript; available in PMC 2020 Nov 7.

Published in final edited form as: Cell Stem Cell. 2019 Nov 7; 25(5): 682–696.e8. Published online 2019 Sep 5. doi: 10.1016/j.stem.2019.08.003

PMCID:: PMC6842438

Abstract Article PDF–3.4M

Select item 677813720.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

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