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Select item 102374221.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 100729062.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 98231313.

Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth

David J. Wisniewski, Mariya S. Liyasova, Soumya Korrapati, Xu Zhang, Shashikala Ratnayake, Qingrong Chen, Samuel F. Gilbert, Alexis Catalano, Donna Voeller, Daoud Meerzaman, Udayan Guha, Natalie Porat-Shliom, Christina M. Annunziata, Stanley Lipkowitz

J Biol Chem. 2023 Jan; 299(1): 102766. Published online 2022 Dec 5. doi: 10.1016/j.jbc.2022.102766

PMCID:: PMC9823131

Abstract Article PDF–2.5M

Select item 97696984.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 95699555.

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation

Yulemi Gonzalez Quesada, Luc DesGroseillers

Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588

PMCID:: PMC9569955

Abstract Article PDF–2.1M

Select item 92792856.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 90982227.

FER-mediated phosphorylation and PIK3R2 recruitment on IRS4 promotes AKT activation and tumorigenesis in ovarian cancer cells

Yanchun Zhang, Xuexue Xiong, Qi Zhu, Jiali Zhang, Shengmiao Chen, Yuetong Wang, Jian Cao, Li Chen, Linjun Hou, Xi Zhao, Piliang Hao, Jian Chen, Min Zhuang, Dake Li, Gaofeng Fan

eLife. 2022; 11: e76183. Published online 2022 May 12. doi: 10.7554/eLife.76183

PMCID:: PMC9098222

Abstract Article PDF–2.3M

Select item 88970228.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 83071949.

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation

Sun-Ok Kim, Kyoung Sang Cho, Bo Yeon Kim, Kyung Ho Lee

Int J Mol Sci. 2021 Jul; 22(14): 7572. Published online 2021 Jul 15. doi: 10.3390/ijms22147572

PMCID:: PMC8307194

Abstract Article PDF–2.8M

Select item 816503010.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 803725611.

Loss of Fer Jeopardizes Metabolic Plasticity and Mitochondrial Homeostasis in Lung and Breast Carcinoma Cells

Linoy Mehazri, Sally Shpungin, Shai Bel, Uri Nir

Int J Mol Sci. 2021 Apr; 22(7): 3387. Published online 2021 Mar 25. doi: 10.3390/ijms22073387

PMCID:: PMC8037256

Abstract Article PDF–9.3M

Select item 782692912.

Fer and FerT Govern Mitochondrial Susceptibility to Metformin and Hypoxic Stress in Colon and Lung Carcinoma Cells

Odeya Marciano, Linoy Mehazri, Sally Shpungin, Alexander Varvak, Eldad Zacksenhaus, Uri Nir

Cells. 2021 Jan; 10(1): 97. Published online 2021 Jan 7. doi: 10.3390/cells10010097

PMCID:: PMC7826929

Abstract Article PDF–44M

Select item 779789913.

Phosphorylation of PKCδ by FER tips the balance from EGFR degradation to recycling

Ana Lonic, Freya Gehling, Leila Belle, Xiaochun Li, Nicole L. Schieber, Elizabeth V. Nguyen, Gregory J. Goodall, Robert G. Parton, Roger J. Daly, Yeesim Khew-Goodall

J Cell Biol. 2021 Feb 1; 220(2): e201902073. Published online 2021 Jan 7. doi: 10.1083/jcb.201902073

PMCID:: PMC7797899

Abstract Article PDF–8.3M

Select item 765725214.

Feline sarcoma‐related protein expression correlates with malignant aggressiveness and poor prognosis in renal cell carcinoma

Yasuyoshi Miyata, Shigeru Kanda, Hideki Sakai, Peter A. Greer

Cancer Sci. 2013 Jun; 104(6): 681–686. Published online 2013 Apr 18. doi: 10.1111/cas.12140

PMCID:: PMC7657252

Abstract Article PDF–1.4M

Select item 765424015.

Detection of novel paraja ring finger 2‐fer tyrosine kinase mRNA chimeras is associated with poor postoperative prognosis in non‐small cell lung cancer

Masanori Kawakami, Rie Ishikawa, Yosuke Amano, Mitsuhiro Sunohara, Kousuke Watanabe, Nobuya Ohishi, Yutaka Yatomi, Jun Nakajima, Masashi Fukayama, Takahide Nagase, Daiya Takai

Cancer Sci. 2013 Nov; 104(11): 1447–1454. Published online 2013 Sep 5. doi: 10.1111/cas.12250

PMCID:: PMC7654240

Abstract Article PDF–957K

Select item 754969916.

FER mediated HGF-independent regulation of HGFR/MET activates RAC1-PAK1 pathway to potentiate metastasis in ovarian cancer

Gaofeng Fan

Small GTPases. 2020; 11(3): 155–159. Published online 2017 Nov 3. doi: 10.1080/21541248.2017.1379931

PMCID:: PMC7549699

Abstract Article PDF–423K

Select item 742732717.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 692775418.

Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC

Hao Zeng, Johnny Castillo-Cabrera, Mika Manser, Bo Lu, Zinger Yang, Vaik Strande, Damien Begue, Raffaella Zamponi, Shumei Qiu, Frederic Sigoillot, Qiong Wang, Alicia Lindeman, John S Reece-Hoyes, Carsten Russ, Debora Bonenfant, Xiaomo Jiang, Youzhen Wang, Feng Cong

eLife. 2019; 8: e50223. Published online 2019 Nov 19. doi: 10.7554/eLife.50223

PMCID:: PMC6927754

Abstract Article PDF–5.1M

Select item 653078619.

Spatial Regulation of Signaling by the Coordinated Action of the Protein Tyrosine Kinases MET and FER

Jiali Zhang, Zuo Wang, Siwei Zhang, Yanxun Chen, Xuexue Xiong, Xiaojuan Li, Nicholas K. Tonks, Gaofeng Fan

Cell Signal. Author manuscript; available in PMC 2019 Oct 1.

Published in final edited form as: Cell Signal. 2018 Oct; 50: 100–110. Published online 2018 Jun 18. doi: 10.1016/j.cellsig.2018.06.006

PMCID:: PMC6530786

Abstract Article PDF–994K

Select item 619583220.

Electroporation-mediated Delivery of FER Gene Enhances Innate Immune Response and Improves Survival in a Murine Model of Pneumonia

Vladislav Dolgachev, Sreehari Panicker, Sanjay Balijepalli, Lane Kelly McCandless, Yue Yin, Samantha Swamy, MV Suresh, Matthew J. Delano, Mark R. Hemmila, Krishnan Raghavendran, David Machado-Aranda

Gene Ther. Author manuscript; available in PMC 2018 Dec 15.

Published in final edited form as: Gene Ther. 2018 Aug; 25(5): 359–375. Published online 2018 Jun 15. doi: 10.1038/s41434-018-0022-y

PMCID:: PMC6195832

Abstract Article PDF–1.8M

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