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Select item 107200901.

Histone demethylase KDM4B accelerates the progression of glioblastoma via the epigenetic regulation of MYC stability

Zhongze Wang, Huarui Cai, Zekun Li, Wei Sun, Erhu Zhao, Hongjuan Cui

Clin Epigenetics. 2023; 15: 192. Published online 2023 Dec 13. doi: 10.1186/s13148-023-01608-4

PMCID:: PMC10720090

Abstract Article PDF–13M

Select item 100380572.

Histone demethylase KDM4B contributes to advanced clear cell renal carcinoma and association with copy number variations and cell cycle progression

Heting Tang, Yaping Guan, Zhihao Yuan, Tuanjie Guo, Xiangyin Tan, Yu Fan, Encheng Zhang, Xiang Wang

Epigenetics. 2023; 18(1): 2192319. Published online 2023 Mar 23. doi: 10.1080/15592294.2023.2192319

PMCID:: PMC10038057

Abstract Article PDF–3.7M

Select item 99224683.

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia

Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen

J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0

PMCID:: PMC9922468

Abstract Article PDF–4.9M

Select item 95475834.

Histone H3K9 demethylase JMJD2B/KDM4B promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells by regulating H3K9me2 on RUNX2

Pan Kang, Zhiming Wu, Yuxi Huang, Zhen Luo, Shaochuan Huo, Qunqun Chen

PeerJ. 2022; 10: e13862. Published online 2022 Oct 5. doi: 10.7717/peerj.13862

PMCID:: PMC9547583

Abstract Article PDF–11M

Select item 95403455.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 91197366.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 90790767.

Loss of KDM4B impairs osteogenic differentiation of OMSCs and promotes oral bone aging

Peng Deng, Insoon Chang, Jiongke Wang, Amr A. Badreldin, Xiyao Li, Bo Yu, Cun-Yu Wang

Int J Oral Sci. 2022; 14: 24. Published online 2022 May 7. doi: 10.1038/s41368-022-00175-3

PMCID:: PMC9079076

Abstract Article PDF–3.2M

Select item 90588368.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Abstract Article PDF–2.9M

Select item 86323359.

TP53/p53-FBXO22-TFEB controls basal autophagy to govern hormesis

Narumi Suzuki, Yoshikazu Johmura, Teh-Wei Wang, Toshiro Migita, Wenwen Wu, Rei Noguchi, Kiyoshi Yamaguchi, Yoichi Furukawa, Shuhei Nakamura, Ichiro Miyoshi, Tamotsu Yoshimori, Tomohiko Ohta, Makoto Nakanishi

Autophagy. 2021; 17(11): 3776–3793. Published online 2021 Mar 11. doi: 10.1080/15548627.2021.1897961

PMCID:: PMC8632335

Abstract Article PDF–17M

Select item 855114910.

KDM4B Overexpression Promotes the Growth, Migration, and Invasion of Rheumatoid Arthritis Fibroblast-Like Synoviocytes by Activating STAT3 Pathway

Xin Zhang, He Nan, Jialong Guo, Jinyu Liu

Biochem Genet. 2021; 59(6): 1427–1440. Published online 2021 Apr 28. doi: 10.1007/s10528-021-10042-1

PMCID:: PMC8551149

Abstract Article PDF–2.1M

Select item 831505111.

Targeting KDM4B that coactivates c-Myc-regulated metabolism to suppress tumor growth in castration-resistant prostate cancer

Meng-Jen Wu, Chih-Jung Chen, Ting-Yu Lin, Ying-Yuan Liu, Lin-Lu Tseng, Mei-Ling Cheng, Chih-Pin Chuu, Huai-Kuang Tsai, Wen-Ling Kuo, Hsing-Jien Kung, Wen-Ching Wang

Theranostics. 2021; 11(16): 7779–7796. Published online 2021 Jun 26. doi: 10.7150/thno.58729

PMCID:: PMC8315051

Abstract Article PDF–2.9M

Select item 826661712.

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins

Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer

Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490

PMCID:: PMC8266617

Abstract Article PDF–4.0M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 792072614.

IL-13 Augments Histone Demethylase JMJD2B/KDM4B Expression Levels, Activity, and Nuclear Translocation in Airway Fibroblasts in Asthma

Khuloud Bajbouj, Mahmood Y. Hachim, Rakhee K. Ramakrishnan, Huwaida Fazel, Jumana Mustafa, Shahed Alzaghari, Mahmoud Eladl, Jasmin Shafarin, Ronald Olivenstein, Qutayba Hamid

J Immunol Res. 2021; 2021: 6629844. Published online 2021 Feb 22. doi: 10.1155/2021/6629844

PMCID:: PMC7920726

Abstract Article PDF–1.9M

Select item 782062015.

Heterozygous Variants in KDM4B Lead to Global Developmental Delay and Neuroanatomical Defects

Anna R. Duncan, Antonio Vitobello, Stephan C. Collins, Valerie E. Vancollie, Christopher J. Lelliott, Lance Rodan, Jiahai Shi, Ann R. Seman, Emanuele Agolini, Antonio Novelli, Paolo Prontera, Maria J. Guillen Sacoto, Teresa Santiago-Sim, Aurélien Trimouille, Cyril Goizet, Mathilde Nizon, Ange-Line Bruel, Christophe Philippe, Patricia E. Grant, Monica H. Wojcik, Joan Stoler, Casie A. Genetti, Marieke F. van Dooren, Saskia M. Maas, Marielle Alders, Laurence Faivre, Arthur Sorlin, Grace Yoon, Binnaz Yalcin, Pankaj B. Agrawal

Am J Hum Genet. 2020 Dec 3; 107(6): 1170–1177. Published online 2020 Nov 23. doi: 10.1016/j.ajhg.2020.11.001

PMCID:: PMC7820620

Abstract Article PDF–1.6M

Select item 766420216.

Histone H3K9 Demethylase JMJD2B Plays a Role in LXRα-Dependent Lipogenesis

Ji-Hyun Kim, Dae Young Jung, Hye-Ran Kim, Myeong Ho Jung

Int J Mol Sci. 2020 Nov; 21(21): 8313. Published online 2020 Nov 5. doi: 10.3390/ijms21218313

PMCID:: PMC7664202

Abstract Article PDF–25M

Select item 741507917.

Association of JMJD2B and Hypoxia-Inducible Factor 1 Expressions with Poor Prognosis in Osteosarcoma

Xujian Liu, Qianqian Zhang, Yi Zhao, Jianjun Xun, Hongzeng Wu, Helin Feng

Anal Cell Pathol (Amst) 2020; 2020: 2563208. Published online 2020 Jul 31. doi: 10.1155/2020/2563208

PMCID:: PMC7415079

Abstract Article PDF–1.0M

Select item 725499318.

JMJD2B-induced amino acid alterations enhance the survival of colorectal cancer cells under glucose-deprivation via autophagy

Juan Tan, Hao-Lian Wang, Jie Yang, Qian-Qian Liu, Chun-Min Li, Yun-Qian Wang, Lin-Na Fu, Qin-Yan Gao, Ying-Xuan Chen, Jing-Yuan Fang

Theranostics. 2020; 10(13): 5763–5777. Published online 2020 Apr 27. doi: 10.7150/thno.38087

PMCID:: PMC7254993

Abstract Article PDF–3.3M

Select item 722080019.

Chromatin Regulators Mediate Anthracycline Sensitivity in Breast Cancer

Jose A. Seoane, Jacob G. Kirkland, Jennifer L. Caswell-Jin, Gerald R. Crabtree, Christina Curtis

Nat Med. Author manuscript; available in PMC 2020 May 13.

Published in final edited form as: Nat Med. 2019 Nov; 25(11): 1721–1727. Published online 2019 Nov 7. doi: 10.1038/s41591-019-0638-5

PMCID:: PMC7220800

Abstract Article PDF–4.4M

Select item 714571520.

Histone lysine demethylase KDM4B regulates the alternative splicing of the androgen receptor in response to androgen deprivation

Lingling Duan, Zhenhua Chen, Jun Lu, Yanping Liang, Ming Wang, Carlos M Roggero, Qing-Jun Zhang, Jason Gao, Yong Fang, Jiazheng Cao, Jian Lu, Hongwei Zhao, Andrew Dang, Rey-Chen Pong, Elizabeth Hernandez, Chun-Mien Chang, David T Hoang, Jung-Mo Ahn, Guanghua Xiao, Rui-tao Wang, Kai-jiang Yu, Payal Kapur, Josep Rizo, Jer-Tsong Hsieh, Junhang Luo, Zhi-Ping Liu

Nucleic Acids Res. 2019 Dec 16; 47(22): 11623–11636. Published online 2019 Oct 24. doi: 10.1093/nar/gkz1004

PMCID:: PMC7145715

Abstract Article PDF–6.1M

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