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Select item 111617561.

Phosphorylation of DNA-binding domains of CLOCK–BMAL1 complex for PER-dependent inhibition in circadian clock of mammalian cells

Yuta Otobe, Eui Min Jeong, Shunsuke Ito, Yuta Shinohara, Nobuhiro Kurabayashi, Atsu Aiba, Yoshitaka Fukada, Jae Kyoung Kim, Hikari Yoshitane

Proc Natl Acad Sci U S A. 2024 Jun 4; 121(23): e2316858121. Published online 2024 May 28. doi: 10.1073/pnas.2316858121

PMCID:: PMC11161756

Abstract Article PDF–4.4M

Select item 111469872.

Regulation of clock genes

Y. Liu, C. Heintzen, J. Loros, J. C. Dunlap

Cell Mol Life Sci. 1999 Aug; 55(10): 1195–1205. doi: 10.1007/s000180050366

PMCID:: PMC11146987

Abstract Article PDF–717K

Select item 110886513.

Chronic circadian rhythm disorder induces heart failure with preserved ejection fraction-like phenotype through the Clock-sGC-cGMP-PKG1 signaling pathway

Yiyang Che, Yuuki Shimizu, Takumi Hayashi, Junya Suzuki, Zhongyue Pu, Kazuhito Tsuzuki, Shingo Narita, Rei Shibata, Toyoaki Murohara

Sci Rep. 2024; 14: 10777. Published online 2024 May 11. doi: 10.1038/s41598-024-61710-2

PMCID:: PMC11088651

Abstract Article PDF–9.4M

Select item 110270884.

Circadian Influence on the Microbiome Improves Heart Failure Outcomes

Priya Mistry, Cristine J. Reitz, Tarak Nath Khatua, Mina Rasouli, Kaitlyn Oliphant, Martin E Young, Emma Allen-Vercoe, Tami A. Martino

J Mol Cell Cardiol. Author manuscript; available in PMC 2024 Apr 19.

Published in final edited form as: J Mol Cell Cardiol. 2020 Dec; 149: 54–72. Published online 2020 Sep 19. doi: 10.1016/j.yjmcc.2020.09.006

PMCID:: PMC11027088

Abstract Article PDF–3.1M

Select item 109176605.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107533586.

Clock gene Per3 deficiency disrupts circadian alterations of gut microbiota in mice : Per3 deficiency disrupts circadian alterations

Xiaoxian Xie, Haoshen Xu, Ruonan Shu, Lei Sun, Mengya Zhang, Qinglian Hu, Kai Zhu, Zezhi Li, Fengchun Wu

Acta Biochim Biophys Sin (Shanghai) 2023 Dec 25; 55(12): 2004–2007. Published online 2023 Nov 15. doi: 10.3724/abbs.2023257

PMCID:: PMC10753358

Article PDF–690K

Select item 106194927.

An aging-susceptible circadian rhythm controls cutaneous antiviral immunity

Stephen J. Kirchner, Vivian Lei, Paul T. Kim, Meera Patel, Jessica L. Shannon, David Corcoran, Dalton Hughes, Diana K. Waters, Kafui Dzirasa, Detlev Erdmann, Jörn Coers, Amanda S. MacLeod, Jennifer Y. Zhang

JCI Insight. 2023 Oct 23; 8(20): e171548. Published online 2023 Oct 23. doi: 10.1172/jci.insight.171548

PMCID:: PMC10619492

Abstract Article PDF–6.6M

Select item 104146368.

miR34a-5p impedes CLOCK expression in chronodisruptive C57BL/6J mice and potentiates pro-atherogenic manifestations

Hitarthi Vyas, Aliasgar Vohra, Kapil Upadhyay, Menaka Thounaojam, Ravirajsinh Jadeja, Nilay Dalvi, Manuela Bartoli, Ranjitsinh Devkar

PLoS One. 2023; 18(8): e0283591. Published online 2023 Aug 10. doi: 10.1371/journal.pone.0283591

PMCID:: PMC10414636

Abstract Article PDF–2.7M

Select item 102974599.

Circadian Disruption Primes Myofibroblasts for Accelerated Activation as a Mechanism Underpinning Fibrotic Progression in Non-Alcoholic Fatty Liver Disease

Elliot Jokl, Jessica Llewellyn, Kara Simpson, Oluwatobi Adegboye, James Pritchett, Leo Zeef, Ian Donaldson, Varinder S. Athwal, Huw Purssell, Oliver Street, Lucy Bennett, Indra Neil Guha, Neil A. Hanley, Qing-Jun Meng, Karen Piper Hanley

Cells. 2023 Jun; 12(12): 1582. Published online 2023 Jun 8. doi: 10.3390/cells12121582

PMCID:: PMC10297459

Abstract Article PDF–4.5M

Select item 953946110.

A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development

Hongyan Yuan, Bo Xie, Xia Yu, Cheng Lin, Meng Li, Yixin Zhang, Xuqiang Zou, Mingjie Lu, Manzhu Zhao, Xiujie Wen

Front Physiol. 2022; 13: 981311. Published online 2022 Sep 23. doi: 10.3389/fphys.2022.981311

PMCID:: PMC9539461

Abstract Article PDF–4.3M

Select item 935708411.

Neuronal Bmal1 regulates retinal angiogenesis and neovascularization in mice

Vijay K. Jidigam, Onkar B. Sawant, Rebecca D. Fuller, Kenya Wilcots, Rupesh Singh, Richard A. Lang, Sujata Rao

Commun Biol. 2022; 5: 792. Published online 2022 Aug 6. doi: 10.1038/s42003-022-03774-2

PMCID:: PMC9357084

Abstract Article PDF–3.0M

Select item 917779412.

Circadian Regulator CLOCK Drives Immunosuppression in Glioblastoma

Wenjing Xuan, Wen-Hao Hsu, Fatima Khan, Madeline Dunterman, Lizhi Pang, Derek A. Wainwright, Atique U. Ahmed, Amy B. Heimberger, Maciej S. Lesniak, Peiwen Chen

Cancer Immunol Res. Author manuscript; available in PMC 2022 Dec 3.

Published in final edited form as: Cancer Immunol Res. 2022 Jun 3; 10(6): 770–784. doi: 10.1158/2326-6066.CIR-21-0559

PMCID:: PMC9177794

Abstract Article PDF–3.4M

Select item 896734213.

The microbiota coordinates diurnal rhythms in innate immunity with the circadian clock

John F. Brooks, II, Cassie L. Behrendt, Kelly A. Ruhn, Syann Lee, Prithvi Raj, Joseph S. Takahashi, Lora V. Hooper

Cell. Author manuscript; available in PMC 2022 Mar 30.

Published in final edited form as: Cell. 2021 Aug 5; 184(16): 4154–4167.e12. Published online 2021 Jul 28. doi: 10.1016/j.cell.2021.07.001

PMCID:: PMC8967342

Abstract Article PDF–2.9M

Select item 886643614.

Effects of fatty acid metabolites on nocturia

Tatsuya Ihara, Hiroshi Shimura, Sachiko Tsuchiya, Mie Kanda, Satoru Kira, Norifumi Sawada, Masayuki Takeda, Takahiko Mitsui, Eiji Shigetomi, Yoichi Shinozaki, Schuichi Koizumi

Sci Rep. 2022; 12: 3050. Published online 2022 Feb 23. doi: 10.1038/s41598-022-07096-5

PMCID:: PMC8866436

Abstract Article PDF–3.2M

Select item 874629415.

Circadian key component CLOCK/BMAL1 interferes with segmentation clock in mouse embryonic organoids

Yasuhiro Umemura, Nobuya Koike, Yoshiki Tsuchiya, Hitomi Watanabe, Gen Kondoh, Ryoichiro Kageyama, Kazuhiro Yagita

Proc Natl Acad Sci U S A. 2022 Jan 4; 119(1): e2114083119. Published online 2021 Dec 20. doi: 10.1073/pnas.2114083119

PMCID:: PMC8746294

Abstract Article PDF–3.2M

Select item 863544616.

Heart neurons use clock genes to control myocyte proliferation

Emmanouil Tampakakis, Harshi Gangrade, Stephanie Glavaris, Myo Htet, Sean Murphy, Brian Leei Lin, Ting Liu, Amir Saberi, Matthew Miyamoto, William Kowalski, Yoh-Suke Mukouyama, Gabsang Lee, Liliana Minichiello, Chulan Kwon

Sci Adv. 2021 Dec; 7(49): eabh4181. Published online 2021 Dec 1. doi: 10.1126/sciadv.abh4181

PMCID:: PMC8635446

Abstract Article PDF–6.2M

Select item 863228317.

Mitochondrial autophagy and cell survival is regulated by the circadian Clock gene in cardiac myocytes during ischemic stress

Inna Rabinovich-Nikitin, Mina Rasouli, Cristine J. Reitz, Illana Posen, Victoria Margulets, Rimpy Dhingra, Tarak N. Khatua, James A. Thliveris, Tami A. Martino, Lorrie A. Kirshenbaum

Autophagy. 2021; 17(11): 3794–3812. Published online 2021 Aug 7. doi: 10.1080/15548627.2021.1938913

PMCID:: PMC8632283

Abstract Article PDF–11M

Select item 859816518.

Susceptibility rhythm to bacterial endotoxin in myeloid clock-knockout mice

Veronika Lang, Sebastian Ferencik, Bharath Ananthasubramaniam, Achim Kramer, Bert Maier

eLife. 2021; 10: e62469. Published online 2021 Oct 18. doi: 10.7554/eLife.62469

PMCID:: PMC8598165

Abstract Article PDF–1.2M

Select item 854040519.

Biphasic Roles of Clock Genes and Bone Morphogenetic Proteins in Gonadotropin Expression by Mouse Gonadotrope Cells

Yoshiaki Soejima, Nahoko Iwata, Yasuhiro Nakano, Koichiro Yamamoto, Atsuhito Suyama, Takahiro Nada, Fumio Otsuka

Int J Mol Sci. 2021 Oct; 22(20): 11186. Published online 2021 Oct 17. doi: 10.3390/ijms222011186

PMCID:: PMC8540405

Abstract Article PDF–2.2M

Select item 853576320.

Antisense-Induced Downregulation of Clock Genes in the Shell Region of the Nucleus Accumbens Reduces Binge Drinking in Mice

Rishi Sharma, Hunter Puckett, Micaela Kemerling, Meet Parikh, Pradeep Sahota, Mahesh Thakkar

Alcohol Clin Exp Res. Author manuscript; available in PMC 2022 Mar 1.

Published in final edited form as: Alcohol Clin Exp Res. 2021 Mar; 45(3): 530–542. Published online 2021 Feb 19. doi: 10.1111/acer.14549

PMCID:: PMC8535763

Abstract Article PDF–2.5M

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