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Select item 111144941.

Oct-1 cooperates with the TATA binding initiation complex to control rapid transcription of human iNOS

Sylvie Reveneau, Thodoris G. Petrakis, Christopher E. Goldring, Aurélie Chantôme, Jean-François Jeannin, Alena Pance

Cell Mol Life Sci. 2012 Aug; 69(15): 2609–2619. Published online 2012 Feb 19. doi: 10.1007/s00018-012-0939-z

PMCID:: PMC11114494

Abstract Article PDF–477K

Select item 109332672.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 108129213.

Transcriptional Coactivator BOB1 (OBF1, OCA-B) Modulates the Specificity of DNA Recognition by the POU-Domain Factors OCT1 and OCT2 in a Monomeric Configuration

Igor B. Nazarov, Danil S. Zilov, Mikhail N. Gordeev, Evgenii V. Potapenko, Nataliya Yeremenko, Alexey N. Tomilin

Biomolecules. 2024 Jan; 14(1): 123. Published online 2024 Jan 17. doi: 10.3390/biom14010123

PMCID:: PMC10812921

Abstract Article PDF–1.5M

Select item 105658764.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 97696985.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 97534496.

Upregulation of IL‐8, osteonectin, and myonectin mRNAs by intermittent hypoxia via OCT1‐ and NRF2‐mediated mechanisms in skeletal muscle cells

Shin Takasawa, Ryogo Shobatake, Asako Itaya‐Hironaka, Mai Makino, Tomoko Uchiyama, Sumiyo Sakuramoto‐Tsuchida, Yoshinori Takeda, Hiroyo Ota, Akiyo Yamauchi

J Cell Mol Med. 2022 Dec; 26(24): 6019–6031. Published online 2022 Dec 1. doi: 10.1111/jcmm.17618

PMCID:: PMC9753449

Abstract Article PDF–510K

Select item 95403457.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 94754628.

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold

Wenjing Yang, Beili Wang, Qian Yu, Te Liu, Tong Li, Tongtong Tian, Anli Jin, Lin Ding, Wei Chen, Hao Wang, Jingrong Xian, Baishen Pan, Jian Zhou, Jia Fan, Xinrong Yang, Wei Guo

Theranostics. 2022; 12(14): 6189–6206. Published online 2022 Aug 21. doi: 10.7150/thno.72134

PMCID:: PMC9475462

Abstract Article PDF–4.6M

Select item 93691629.

Substrates of the Human Brain Proton-Organic Cation Antiporter and Comparison with Organic Cation Transporter 1 Activities

David A. Doetsch, Salim Ansari, Ole Jensen, Lukas Gebauer, Christof Dücker, Jürgen Brockmöller, Alexandra Sachkova

Int J Mol Sci. 2022 Aug; 23(15): 8430. Published online 2022 Jul 29. doi: 10.3390/ijms23158430

PMCID:: PMC9369162

Abstract Article PDF–1.4M

Select item 927928510.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 911973611.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 882889512.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 881934313.

Hypoxia‐inducible lncRNA MIR210HG interacting with OCT1 is involved in glioblastoma multiforme malignancy

Kuo‐Hao Ho, Chwen‐Ming Shih, Ann‐Jeng Liu, Ku‐Chung Chen

Cancer Sci. 2022 Feb; 113(2): 540–552. Published online 2021 Dec 23. doi: 10.1111/cas.15240

PMCID:: PMC8819343

Abstract Article PDF–2.9M

Select item 862828814.

Positive feedback loop of lncRNA FAM201A/miR-146a-5p/POU2F1 regulates IL-1β-induced chondrocyte injury in vitro

Kaifeng Gan, Wei Wu, Jie Li, Dingli Xu, Yunpeng Liu, Mingguang Bi, Liangjie Lu, Jin Li

Mol Med Rep. 2022 Jan; 25(1): 20. Published online 2021 Nov 18. doi: 10.3892/mmr.2021.12536

PMCID:: PMC8628288

Abstract Article PDF–3.6M

Select item 858402015.

OCT1 Is a Poor Prognostic Factor for Breast Cancer Patients and Promotes Cell Proliferation via Inducing NCAPH

Takuya Ogura, Kotaro Azuma, Junichiro Sato, Keiichi Kinowaki, Ken-Ichi Takayama, Toshihiko Takeiwa, Hidetaka Kawabata, Satoshi Inoue

Int J Mol Sci. 2021 Nov; 22(21): 11505. Published online 2021 Oct 25. doi: 10.3390/ijms222111505

PMCID:: PMC8584020

Abstract Article PDF–1.4M

Select item 845843916.

Primate-specific stress-induced transcription factor POU2F1Z protects human neuronal cells from stress

Alexander G. Stepchenko, Tatiana N. Portseva, Ivan A. Glukhov, Alina P. Kotnova, Bella M. Lyanova, Sofia G. Georgieva, Elizaveta V. Pankratova

Sci Rep. 2021; 11: 18808. Published online 2021 Sep 22. doi: 10.1038/s41598-021-98323-y

PMCID:: PMC8458439

Abstract Article PDF–1.8M

Select item 822039117.

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα

Evelyn Ramberger, Valeria Sapozhnikova, Elisabeth Kowenz-Leutz, Karin Zimmermann, Nathalie Nicot, Petr V. Nazarov, Daniel Perez-Hernandez, Ulf Reimer, Philipp Mertins, Gunnar Dittmar, Achim Leutz

iScience. 2021 Jun 25; 24(6): 102686. Published online 2021 Jun 4. doi: 10.1016/j.isci.2021.102686

PMCID:: PMC8220391

Abstract Article PDF–4.4M

Select item 816503018.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 767054819.

Transcription factor Oct1 protects against hematopoietic stress and promotes acute myeloid leukemia

Jillian L. Jafek, Arvind Shakya, Pei-Yi Tai, Andrea Ibarra, Heejoo Kim, Jessica Maddox, Jeffrey Chumley, Gerald J. Spangrude, Rodney R. Miles, Todd W. Kelley, Dean Tantin

Exp Hematol. Author manuscript; available in PMC 2020 Nov 17.

Published in final edited form as: Exp Hematol. 2019 Aug; 76: 38–48.e2. Published online 2019 Jul 8. doi: 10.1016/j.exphem.2019.07.002

PMCID:: PMC7670548

Abstract Article PDF–1.2M

Select item 756688120.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

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