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Items: 1 to 20 of 494

1.
FA-SAT ncRNA interacts with PKM2 protein: depletion of this complex induces a switch from cell proliferation to apoptosis
Daniela Ferreira, Ana Escudeiro, Filomena Adega, Sandra I. Anjo, Bruno Manadas, Raquel Chaves
Cell Mol Life Sci. 2020 Apr; 77(7): 1371–1386. Published online 2019 Jul 25. doi: 10.1007/s00018-019-03234-x
PMCID:
PMC11104958
AbstractArticlePDF–2.9M
2.
CircPHGDH downregulation decreases papillary thyroid cancer progression through miR-122-5p/PKM2 axis
Jiying Shen, Zhirong Ma, Jin Yang, Tianzhen Qu, Yu Xia, Yingjie Xu, Ming Zhou, Weiwei Liu
BMC Cancer. 2024; 24: 511. Published online 2024 Apr 23. doi: 10.1186/s12885-024-12199-5
PMCID:
PMC11036668
AbstractArticlePDF–6.8M
3.
磷酸化PKM2调控糖尿病内皮依赖性血管舒张功能
鲁 斌, 唐 磊, 李 乐, 周 晓煜, 冷 一平, 全 承炫
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2023 May 28; 48(5): 663–670. Chinese. doi: 10.11817/j.issn.1672-7347.2023.220541
PMCID:
PMC10930405
AbstractArticlePDF–1.4M
4.
PKM2 promotes lymphatic metastasis of hypopharyngeal carcinoma via regulating epithelial-mesenchymal transition: an experimental research
Xin Zhou, Yanshi Li, Min Pan, Tao Lu, Chuan Liu, Zhihai Wang, Fengxiang Tang, Guohua Hu
Diagn Pathol. 2024; 19: 48. Published online 2024 Mar 2. doi: 10.1186/s13000-024-01474-5
PMCID:
PMC10907999
AbstractArticlePDF–12M
5.
Long noncoding RNA TMPO-AS1 accelerates glycolysis by regulating the miR-1270/PKM2 axis in colorectal cancer
Yingmin Jin, Aimin Jiang, Liying Sun, Yue Lu
BMC Cancer. 2024; 24: 238. Published online 2024 Feb 21. doi: 10.1186/s12885-024-11964-w
PMCID:
PMC10880273
AbstractArticlePDF–4.9M
6.
RBMX通过下调PKM2抑制膀胱癌细胞的增殖、迁移、侵袭和糖酵解
颜 秋霞, 曾 鹏, 黄 树强, 谭 翠钰, 周 秀琴, 乔 静, 赵 晓英, 冯 玲, 朱 振杰, 张 国志, 胡 鸿, 陈 彩蓉
Nan Fang Yi Ke Da Xue Xue Bao. 2024 Jan 20; 44(1): 9–16. Chinese. doi: 10.12122/j.issn.1673-4254.2024.01.02
PMCID:
PMC10878900
AbstractArticlePDF–2.9M
7.
TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence
Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang
Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6
PMCID:
PMC10764958
AbstractArticlePDF–4.4M
8.
Elevated plasma pyruvate kinase M2 concentrations are associated with the clinical severity and prognosis of coronary artery disease
Zi-wen Zhao, Yi-wei Xu, Xin-tao Zhang, Hang-hao Ma, Jing-kun Zhang, Xue Wu, Yu Huang
Biochem Med (Zagreb) 2024 Feb 15; 34(1): 010704. Published online 2023 Dec 15. doi: 10.11613/BM.2024.010704
PMCID:
PMC10731730
AbstractArticlePDF–211K
9.
GLUT-1/PKM2 loop dysregulation in patients with non-ST-segment elevation myocardial infarction promotes metainflammation
Francesco Canonico, Daniela Pedicino, Anna Severino, Ramona Vinci, Davide Flego, Eugenia Pisano, Alessia d’Aiello, Pellegrino Ciampi, Myriana Ponzo, Alice Bonanni, Astrid De Ciutiis, Sara Russo, Marianna Di Sario, Giulia Angelini, Piotr Szczepaniak, Alfonso Baldi, Boguslaw Kapelak, Karol Wierzbicki, Rocco A Montone, Domenico D’Amario, Massimo Massetti, Tomasz J Guzik, Filippo Crea, Giovanna Liuzzo
Cardiovasc Res. 2023 Nov; 119(16): 2653–2662. Published online 2022 Dec 13. doi: 10.1093/cvr/cvac184
PMCID:
PMC10730239
AbstractArticlePDF–531K
10.
PKM2 is a potential prognostic biomarker and related to immune infiltration in lung cancer
Lan Yin, Jiaying Shi, Jingfei Zhang, Xinyu Lin, Wenhao Jiang, Yingchuan Zhu, Yue Song, Yilu Lu, Yongxin Ma
Sci Rep. 2023; 13: 22243. Published online 2023 Dec 14. doi: 10.1038/s41598-023-49558-4
PMCID:
PMC10721847
AbstractArticlePDF–11M
11.
Pyruvate Kinase Differentially Alters Metabolic Signatures during Head and Neck Carcinogenesis
Pei-Chun Huang, Ching-Wen Chang, Yu-Cheng Lin, Chang-Yi Chen, Tsai-Ying Chen, Lu-Te Chuang, Chung-Ji Liu, Chien-Ling Huang, Wan-Chun Li
Int J Mol Sci. 2023 Dec; 24(23): 16639. Published online 2023 Nov 23. doi: 10.3390/ijms242316639
PMCID:
PMC10706023
AbstractArticlePDF–3.6M
12.
Transcription factor LHX9 (LIM Homeobox 9) enhances pyruvate kinase PKM2 activity to induce glycolytic metabolic reprogramming in cancer stem cells, promoting gastric cancer progression
Hongying Zhao, Rongke Jiang, Zhijing Feng, Xue Wang, Chunmei Zhang
J Transl Med. 2023; 21: 833. Published online 2023 Nov 18. doi: 10.1186/s12967-023-04658-7
PMCID:
PMC10657563
AbstractArticlePDF–2.4M
13.
The Complex Effects of PKM2 and PKM2:IP3R Disruption on Intracellular Ca2+ Handling and Cellular Functions
Fernanda O. Lemos, Ian de Ridder, Martin D. Bootman, Geert Bultynck, Jan B. Parys
Cells. 2023 Nov; 12(21): 2527. Published online 2023 Oct 26. doi: 10.3390/cells12212527
PMCID:
PMC10647343
AbstractArticlePDF–4.1M
14.
Circular RNA P4HB promotes glycolysis and tumor progression by binding with PKM2 in lung adenocarcinoma
Haoran Li, Haifa Guo, Qi Huang, Shaodong Wang, Xiao Li, Mantang Qiu
Respir Res. 2023; 24: 252. Published online 2023 Oct 25. doi: 10.1186/s12931-023-02563-7
PMCID:
PMC10601333
AbstractArticlePDF–8.0M
15.
UCHL1-PKM2 axis dysregulation is associated with promoted proliferation and invasiveness of urothelial bladder cancer cells
Yuhui Zheng, Dongliang Shi, Linlin Chen, Yinghong Yang, Meihong Yao
Aging (Albany NY) 2023 Oct 15; 15(19): 10593–10606. Published online 2023 Oct 9. doi: 10.18632/aging.205097
PMCID:
PMC10599732
AbstractArticlePDF–1.6M
16.
Non-metabolic enzyme function of PKM2 in hepatocellular carcinoma: A review
Shuangxia Zhang, Zhangxiu Liao, Shubo Li, Ying Luo
Medicine (Baltimore) 2023 Oct 20; 102(42): e35571. Published online 2023 Oct 20. doi: 10.1097/MD.0000000000035571
PMCID:
PMC10589597
AbstractArticlePDF–1.0M
17.
LncRNA FTO-IT1 promotes glycolysis and progression of hepatocellular carcinoma through modulating FTO-mediated N6-methyladenosine modification on GLUT1 and PKM2
Fan Wang, Yuhang Hu, Hongda Wang, Ping Hu, Hewei Xiong, Zhu Zeng, Shengbo Han, Decai Wang, Jie Wang, Yong Zhao, Yan Huang, Wenfeng Zhuo, Guozheng Lv, Gang Zhao
J Exp Clin Cancer Res. 2023; 42: 267. Published online 2023 Oct 16. doi: 10.1186/s13046-023-02847-2
PMCID:
PMC10578010
AbstractArticlePDF–8.7M
18.
Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex
Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté
J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123
PMCID:
PMC10480535
AbstractArticlePDF–2.4M
19.
LncRNA HClnc1 facilitates hepatocellular carcinoma progression by regulating PKM2 signaling and indicates poor survival outcome after hepatectomy
Qian Zhu, Zhengqing Lei, Chang Xu, Zheng Zhang, Zeqian Yu, Zhangjun Cheng, Pengfeng Xiao, Shufeng Li, Weiping Yu, Jiahua Zhou
Cancer Med. 2023 Jul; 12(13): 14526–14544. Published online 2023 May 22. doi: 10.1002/cam4.6117
PMCID:
PMC10358232
AbstractArticlePDF–20M
20.
Pyruvate Kinase M (PKM) binds ribosomes in a poly-ADP ribosylation dependent manner to induce translational stalling
Nevraj S Kejiou, Lena Ilan, Stefan Aigner, Enching Luo, Tori Tonn, Hakan Ozadam, Muyoung Lee, Gregory B Cole, Ines Rabano, Nishani Rajakulendran, Brian A Yee, Hamed S Najafabadi, Trevor F Moraes, Stephane Angers, Gene W Yeo, Can Cenik, Alexander F Palazzo
Nucleic Acids Res. 2023 Jul 7; 51(12): 6461–6478. Published online 2023 May 24. doi: 10.1093/nar/gkad440
PMCID:
PMC10325899
AbstractArticlePDF–1.6M

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